732
Views
72
CrossRef citations to date
0
Altmetric
Reviews

Clinical translation of folate receptor-targeted therapeutics

, , & , PhD
Pages 901-908 | Published online: 05 Jun 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Shufeng Yan, Qingqing Huang, Jincan Chen, Xiaorong Song, Zhuo Chen, Mingdong Huang, Peng Xu & Juncheng Zhang. (2019) Tumor-targeting photodynamic therapy based on folate-modified polydopamine nanoparticles. International Journal of Nanomedicine 14, pages 6799-6812.
Read now
Ying Zhou, Kenji Unno, Elizabeth Hyjek, Hui Liu, Todd Zimmerman, Subhradip Karmakar, Karson S. Putt, Jiayin Shen, Philip S. Low & Amittha Wickrema. (2018) Expression of functional folate receptors in multiple myeloma. Leukemia & Lymphoma 59:12, pages 2982-2989.
Read now
Loredana Serpe, Margherita Gallicchio, Roberto Canaparo & Franco Dosio. (2014) Targeted treatment of folate receptor-positive platinum-resistant ovarian cancer and companion diagnostics, with specific focus on vintafolide and etarfolatide. Pharmacogenomics and Personalized Medicine 7, pages 31-42.
Read now
Umberto Leone Roberti Maggiore, Filippo Bellati, Ilary Ruscito, Maria Luisa Gasparri, Franco Alessandri, Pier Luigi Venturini & Simone Ferrero. (2013) Monoclonal antibodies therapies for ovarian cancer. Expert Opinion on Biological Therapy 13:5, pages 739-764.
Read now

Articles from other publishers (68)

Pavitra Varaganti, Viswanath Buddolla, Buddolla Anantha Lakshmi & Young-Joon Kim. (2023) Recent advances in using folate receptor 1 (FOLR1) for cancer diagnosis and treatment, with an emphasis on cancers that affect women. Life Sciences 326, pages 121802.
Crossref
Naveen Rajana, Aare Mounika, Padakanti Sandeep Chary, Valamla Bhavana, Anuradha Urati, Dharmendra Khatri, Shashi Bala Singh & Neelesh Kumar Mehra. (2022) Multifunctional hybrid nanoparticles in diagnosis and therapy of breast cancer. Journal of Controlled Release 352, pages 1024-1047.
Crossref
Yafang Qin, Xingguo Tang, Jintai Chen, Jingcong Huang, Dingding Wang, Xianhuan Zhang, Yangli Zhang, Fenglin Wu & Jinquan Wang. (2022) An LHRH peptide-conjugated ruthenium(II) complex as tumor-targeted theranostic anticancer agent. Inorganic Chemistry Communications 136, pages 109166.
Crossref
Patrycja Guzik, Hsin-Yu Fang, Luisa M. Deberle, Martina Benešová, Susan Cohrs, Silvan D. Boss, Simon M. Ametamey, Roger Schibli & Cristina Müller. (2021) Identification of a PET Radiotracer for Imaging of the Folate Receptor-α: A Potential Tool to Select Patients for Targeted Tumor Therapy. Journal of Nuclear Medicine 62:10, pages 1475-1481.
Crossref
Taylor Hanley, Raviraj Vankayala, Chi-Hua Lee, Jack C. Tang, Joshua M. Burns & Bahman Anvari. (2021) Phototheranostics Using Erythrocyte-Based Particles. Biomolecules 11:5, pages 729.
Crossref
Antonella Grigoletto, Tommaso Tedeschini, Elena Canato & Gianfranco Pasut. (2020) The evolution of polymer conjugation and drug targeting for the delivery of proteins and bioactive molecules. WIREs Nanomedicine and Nanobiotechnology 13:3.
Crossref
Silvano Gnesin, Joachim Müller, Irene A. Burger, Alexander Meisel, Marco Siano, Martin Früh, Matthias Choschzick, Cristina Müller, Roger Schibli, Simon M. Ametamey, Philipp A. Kaufmann, Valerie Treyer, John O. Prior & Niklaus Schaefer. (2020) Radiation dosimetry of 18F-AzaFol: A first in-human use of a folate receptor PET tracer. EJNMMI Research 10:1.
Crossref
Taylor M. Hanley, Raviraj Vankayala, Jenny T. Mac, David D. Lo & Bahman Anvari. (2020) Acute Immune Response of Micro- and Nanosized Erythrocyte-Derived Optical Particles in Healthy Mice. Molecular Pharmaceutics 17:10, pages 3900-3914.
Crossref
Albert Gandioso, Anna Rovira, Huayun Shi, Peter J. Sadler & Vicente Marchán. (2020) Unexpected photoactivation pathways in a folate-receptor-targeted trans -diazido Pt( iv ) anticancer pro-drug . Dalton Transactions 49:34, pages 11828-11834.
Crossref
Priti Tagde, Giriraj T Kulkarni, Dinesh Kumar Mishra & Prashant Kesharwani. (2020) Recent advances in folic acid engineered nanocarriers for treatment of breast cancer. Journal of Drug Delivery Science and Technology 56, pages 101613.
Crossref
Yuhua Weng, Qianqian Huang, Chunhui Li, Yongfeng Yang, Xiaoxia Wang, Jie Yu, Yuanyu Huang & Xing-Jie Liang. (2020) Improved Nucleic Acid Therapy with Advanced Nanoscale Biotechnology. Molecular Therapy - Nucleic Acids 19, pages 581-601.
Crossref
Dinglin Zhang & Jianxiang Zhang. (2020) Surface engineering of nanomaterials with phospholipid-polyethylene glycol-derived functional conjugates for molecular imaging and targeted therapy. Biomaterials 230, pages 119646.
Crossref
Melek Karaca & Yıldız Özsoy. 2019. Nanoarchitectonics in Biomedicine. Nanoarchitectonics in Biomedicine 411 436 .
Bhagyashri Joshi, Sukhada S. Shevade, Prajakta Dandekar & Padma V. Devarajan. 2019. Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis. Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis 407 431 .
Horacio Cabral, Kanjiro Miyata, Kensuke Osada & Kazunori Kataoka. (2018) Block Copolymer Micelles in Nanomedicine Applications. Chemical Reviews 118:14, pages 6844-6892.
Crossref
Gerardo J. Ramírez-Nava, Clara L. Santos-Cuevas, Isaac Chairez & Liliana Aranda-Lara. (2017) Multimodal molecular 3D imaging for the tumoral volumetric distribution assessment of folate-based biosensors. Medical & Biological Engineering & Computing 56:7, pages 1135-1148.
Crossref
Cristina Müller, Patrycja Guzik, Klaudia Siwowska, Susan Cohrs, Raffaella Schmid & Roger Schibli. (2018) Combining Albumin-Binding Properties and Interaction with Pemetrexed to Improve the Tissue Distribution of Radiofolates. Molecules 23:6, pages 1465.
Crossref
Ksenia Lisova, Maxim Sergeev, Susan Evans-Axelsson, Andreea D. Stuparu, Seval Beykan, Jeffrey Collins, Jason Jones, Michael Lassmann, Ken Herrmann, David Perrin, Jason T. Lee, Roger Slavik & R. Michael van Dam. (2018) Microscale radiosynthesis, preclinical imaging and dosimetry study of [18F]AMBF3-TATE: A potential PET tracer for clinical imaging of somatostatin receptors. Nuclear Medicine and Biology 61, pages 36-44.
Crossref
Marta Overchuk & Gang Zheng. (2018) Overcoming obstacles in the tumor microenvironment: Recent advancements in nanoparticle delivery for cancer theranostics. Biomaterials 156, pages 217-237.
Crossref
Jiayin Shen, Yingwen Hu, Karson S. Putt, Sunil Singhal, Haiyong Han, Daniel W. Visscher, Linda M. Murphy & Philip S. Low. (2017) Assessment of folate receptor alpha and beta expression in selection of lung and pancreatic cancer patients for receptor targeted therapies. Oncotarget 9:4, pages 4485-4495.
Crossref
Marcos Fernández, Faiza Javaid & Vijay Chudasama. (2018) Advances in targeting the folate receptor in the treatment/imaging of cancers. Chemical Science 9:4, pages 790-810.
Crossref
E. Péraudeau, L. Cronier, A. Monvoisin, P. Poinot, C. Mergault, F. Guilhot, I. Tranoy-Opalinski, B. Renoux, S. Papot & J. Clarhaut. (2018) Enhancing tumor response to targeted chemotherapy through up-regulation of folate receptor α expression induced by dexamethasone and valproic acid. Journal of Controlled Release 269, pages 36-44.
Crossref
Stefania Ferrari, Leda Severi, Cecilia Pozzi, Antonio Quotadamo, Glauco Ponterini, Lorena Losi, Gaetano Marverti & Maria Paola Costi. 2018. Ovarian Cycle. Ovarian Cycle 473 513 .
Daxiang Cui. 2018. Handbook of Nanomaterials for Cancer Theranostics. Handbook of Nanomaterials for Cancer Theranostics 305 349 .
Dah-Shyong Yu, Hui-Yu Yan & Chia-Lun Wu. (2017) Folate receptor expression in bladder cancer and its correlation with tumor behaviors and clinical outcome. Journal of Cancer Research and Practice 4:4, pages 130-133.
Crossref
Ilaria Colombo, Marta Overchuk, Juan Chen, Raymond M. Reilly, Gang Zheng & Stephanie Lheureux. (2017) Molecular imaging in drug development: Update and challenges for radiolabeled antibodies and nanotechnology. Methods 130, pages 23-35.
Crossref
Magdalena Ceborska. (2017) Folate appended cyclodextrins for drug, DNA, and siRNA delivery. European Journal of Pharmaceutics and Biopharmaceutics 120, pages 133-145.
Crossref
Pritam Thapa, Mengjie Li, Radha Karki, Moses Bio, Pallavi Rajaputra, Gregory Nkepang, Sukyung Woo & Youngjae You. (2017) Folate-PEG Conjugates of a Far-Red Light-Activatable Paclitaxel Prodrug to Improve Selectivity toward Folate Receptor-Positive Cancer Cells. ACS Omega 2:10, pages 6349-6360.
Crossref
Dian-Jang Lee, Eva Kessel, Taavi Lehto, Xueying Liu, Naoto Yoshinaga, Kärt Padari, Ying-Chen Chen, Susanne Kempter, Satoshi Uchida, Joachim O. Rädler, Margus Pooga, Ming-Thau Sheu, Kazunori Kataoka & Ernst Wagner. (2017) Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia . Bioconjugate Chemistry 28:9, pages 2393-2409.
Crossref
M. Michael Dcona, Jonathon E. Sheldon, Deboleena Mitra & Matthew C.T. Hartman. (2017) Light induced drug release from a folic acid-drug conjugate. Bioorganic & Medicinal Chemistry Letters 27:3, pages 466-469.
Crossref
Ana M. Martínez, Marta Benito, Elena Pérez & María D. Blanco. 2017. Nanostructures for Cancer Therapy. Nanostructures for Cancer Therapy 329 350 .
Daxiang Cui. 2017. Gastric Cancer Prewarning and Early Diagnosis System. Gastric Cancer Prewarning and Early Diagnosis System 195 238 .
Even Walseng, Christopher G. Nelson, Junpeng Qi, Alex R. Nanna, William R. Roush, Rajib K. Goswami, Subhash.C. Sinha, Terrence R. BurkeJr.Jr. & Christoph Rader. (2016) Chemically Programmed Bispecific Antibodies in Diabody Format. Journal of Biological Chemistry 291:37, pages 19661-19673.
Crossref
V.B. Kraus, G. McDaniel, J.L. Huebner, T.V. Stabler, C.F. Pieper, S.W. Shipes, N.A. Petry, P.S. Low, J. Shen, T.A. McNearney & P. Mitchell. (2016) Direct in vivo evidence of activated macrophages in human osteoarthritis. Osteoarthritis and Cartilage 24:9, pages 1613-1621.
Crossref
Renáta Farkas, Klaudia Siwowska, Simon M. Ametamey, Roger Schibli, Nicholas P. van der Meulen & Cristina Müller. (2016) 64 Cu- and 68 Ga-Based PET Imaging of Folate Receptor-Positive Tumors: Development and Evaluation of an Albumin-Binding NODAGA–Folate . Molecular Pharmaceutics 13:6, pages 1979-1987.
Crossref
Liliana Aranda-Lara, Guillermina Ferro-Flores, Flor de María Ramírez, Blanca Ocampo-García, Clara Santos-Cuevas, Lorenza Díaz-Nieto & Keila Isaac-Olivé. (2016) Improved radiopharmaceutical based on 99mTc-Bombesin–folate for breast tumour imaging. Nuclear Medicine Communications 37:4, pages 377-386.
Crossref
Cheng Fang, Kun Wang, Chaoting Zeng, Chongwei Chi, Wenting Shang, Jinzuo Ye, Yamin Mao, Yingfang Fan, Jian Yang, Nan Xiang, Ning Zeng, Wen Zhu, Chihua Fang & Jie Tian. (2016) Illuminating necrosis: From mechanistic exploration to preclinical application using fluorescence molecular imaging with indocyanine green. Scientific Reports 6:1.
Crossref
Héctor Mendoza-Nava, Guillermina Ferro-Flores, Flor de María Ramírez, Blanca Ocampo-García, Clara Santos-Cuevas, Liliana Aranda-Lara, Erika Azorín-Vega, Enrique Morales-Avila & Keila Isaac-Olivé. (2016) 177 Lu-Dendrimer Conjugated to Folate and Bombesin with Gold Nanoparticles in the Dendritic Cavity: A Potential Theranostic Radiopharmaceutical . Journal of Nanomaterials 2016, pages 1-11.
Crossref
Song Hua, Jiahua Yu, Jun Shang, Haowen Zhang, Jie Du, Yushuo Zhang, Fei Chen, Yuan Zhou & Fenju Liu. (2016) Effective tumor-targeted delivery of etoposide using chitosan nanoparticles conjugated with folic acid and sulfobetaine methacrylate. RSC Advances 6:94, pages 91192-91200.
Crossref
Raj Kumar Thapa, Ju Yeon Choi, Biki Gupta, Thiruganesh Ramasamy, Bijay Kumar Poudel, Sae Kwang Ku, Yu Seok Youn, Han Gon Choi, Chul Soon Yong & Jong Oh Kim. (2016) Liquid crystalline nanoparticles encapsulating cisplatin and docetaxel combination for targeted therapy of breast cancer. Biomaterials Science 4:9, pages 1340-1350.
Crossref
Liliana Aranda-Lara, Guillermina Ferro-Flores, Erika Azorín-Vega, Flor de María Ramírez, Nallely Jiménez-Mancilla, Blanca Ocampo-García, Clara Santos-Cuevas & Keila Isaac-Olivé. (2016) Synthesis and evaluation of Lys 1 (α,γ-Folate)Lys 3 ( 177 Lu-DOTA)-Bombesin(1-14) as a potential theranostic radiopharmaceutical for breast cancer. Applied Radiation and Isotopes 107, pages 214-219.
Crossref
Daxiang Cui. 2016. Advances in Nanotheranostics II. Advances in Nanotheranostics II 225 271 .
Masaharu Somiya & Shun'ichi Kuroda. (2015) Development of a virus-mimicking nanocarrier for drug delivery systems: The bio-nanocapsule. Advanced Drug Delivery Reviews 95, pages 77-89.
Crossref
Myoung Hyoun Kim, Woo Hyoung Kim, Chang Guhn Kim & Dae-Weung Kim. (2015) Synthesis and Evaluation of 99mTc-Labeled Folate-Tripeptide Conjugate as a Folate Receptor-Targeted Imaging Agent in a Tumor-Bearing Mouse Model. Nuclear Medicine and Molecular Imaging 49:3, pages 200-207.
Crossref
Daxiang Cui, Chunlei Zhang, Bing Liu, Yi Shu, Tong Du, Dan Shu, Kan Wang, Fangping Dai, Yanlei Liu, Chao Li, Fei Pan, Yuming Yang, Jian Ni, Hui Li, Beate Brand-Saberi & Peixuan Guo. (2015) Regression of Gastric Cancer by Systemic Injection of RNA Nanoparticles Carrying both Ligand and siRNA. Scientific Reports 5:1.
Crossref
Ignace Vergote & Christopher P. Leamon. (2015) Vintafolide: a novel targeted therapy for the treatment of folate receptor expressing tumors. Therapeutic Advances in Medical Oncology 7:4, pages 206-218.
Crossref
Sanja A. Farkas, Rahel Befekadu, Victoria Hahn-Str?mberg & Torbj?rn K. Nilsson. (2015) DNA methylation and expression of the folate transporter genes in colorectal cancer. Tumor Biology 36:7, pages 5581-5590.
Crossref
Jiayin Shen, Karson S. Putt, Daniel W. Visscher, Linda Murphy, Cynthia Cohen, Sunil Singhal, George Sandusky, Yang Feng, Dimiter S. Dimitrov & Philip S. Low. (2015) Assessment of folate receptor-β expression in human neoplastic tissues. Oncotarget 6:16, pages 14700-14709.
Crossref
Taku NagaiYuko FurushoHua LiKazuhisa HasuiSumika MatsukitaKazunobu SueyoshiMasakazu YanagiMasaki HataeSonshin TakaoTakami Matsuyama. (2015) Production of a High-affinity Monoclonal Antibody Reactive with Folate Receptors Alpha and Beta. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy 34:3, pages 181-190.
Crossref
Ignace B. Vergote, Christian Marth & Robert L. Coleman. (2015) Role of the folate receptor in ovarian cancer treatment: evidence, mechanism, and clinical implications. Cancer and Metastasis Reviews 34:1, pages 41-52.
Crossref
Laura Wortmann, Shaista Ilyas, Daniel Niznansky, Martin Valldor, Karim Arroub, Nadja Berger, Kamil Rahme, Justin Holmes & Sanjay Mathur. (2014) Bioconjugated Iron Oxide Nanocubes: Synthesis, Functionalization, and Vectorization. ACS Applied Materials & Interfaces 6:19, pages 16631-16642.
Crossref
Yehuda G. Assaraf, Christopher P. Leamon & Joseph A. Reddy. (2014) The folate receptor as a rational therapeutic target for personalized cancer treatment. Drug Resistance Updates 17:4-6, pages 89-95.
Crossref
I Fuso Nerini, L Morosi, M Zucchetti, A Ballerini, R Giavazzi & M D?Incalci. (2014) Intratumor Heterogeneity and Its Impact on Drug Distribution and Sensitivity. Clinical Pharmacology & Therapeutics 96:2, pages 224-238.
Crossref
Alan H. Maurer, Philip Elsinga, Stefano Fanti, Binh Nguyen, Wim J.G. Oyen & Wolfgang A. Weber. (2014) Imaging the Folate Receptor on Cancer Cells with 99m Tc-Etarfolatide: Properties, Clinical Use, and Future Potential of Folate Receptor Imaging . Journal of Nuclear Medicine 55:5, pages 701-704.
Crossref
Luís Novo, Enrico Mastrobattista, Cornelus F. van Nostrum & Wim E. Hennink. (2014) Targeted Decationized Polyplexes for Cell Specific Gene Delivery. Bioconjugate Chemistry 25:4, pages 802-812.
Crossref
Christian Bailly. 2014. Outstanding Marine Molecules. Outstanding Marine Molecules 377 386 .
Whitney S Graybill & Robert L Coleman. (2014) Vintafolide: a novel targeted agent for epithelial ovarian cancer. Future Oncology 10:4, pages 541-548.
Crossref
Christian Bailly. (2013) Cell-targeted cytotoxics: a new generation of cytotoxic agents for cancer treatment. Phytochemistry Reviews 13:1, pages 171-181.
Crossref
Su-Eon Jin, Hyo-Eon Jin & Soon-Sun Hong. (2014) Targeted Delivery System of Nanobiomaterials in Anticancer Therapy: From Cells to Clinics. BioMed Research International 2014, pages 1-23.
Crossref
Sophie-Dorothee Clas, Rosa I. Sanchez & Rebecca Nofsinger. (2014) Chemistry-enabled drug delivery (prodrugs): recent progress and challenges. Drug Discovery Today 19:1, pages 79-87.
Crossref
Yingjuan Lu, Kristin N. Wollak, Vicky A. Cross, Elaine Westrick, Leroy W. Wheeler, Torian W. Stinnette, Jeremy F. Vaughn, Spencer J. Hahn, Le-Cun Xu, Iontcho R. Vlahov & Christopher P. Leamon. (2014) Folate receptor-targeted aminopterin therapy is highly effective and specific in experimental models of autoimmune uveitis and autoimmune encephalomyelitis. Clinical Immunology 150:1, pages 64-77.
Crossref
Paola B. Arimondo, Nicolas Guilbaud & Christian Bailly. 2014. Cancer Drug Design and Discovery. Cancer Drug Design and Discovery 177 191 .
Vanessa M. Peterson, Cesar M. Castro, Jaehoon ChungNathan C. Miller, Adeeti V. Ullal, Maria D. CastanoRichard T. Penson, Hakho LeeMichael J. Birrer & Ralph Weissleder. (2013) Ascites analysis by a microfluidic chip allows tumor-cell profiling. Proceedings of the National Academy of Sciences 110:51.
Crossref
Zhi-Yao He, Xia-Wei Wei, Min Luo, Shun-Tao Luo, Yang Yang, Yi-Yi Yu, Yan Chen, Cui-Cui Ma, Xiao Liang, Fu-Chun Guo, Ting-Hong Ye, Hua-Shan Shi, Guo-Bo Shen, Wei Wang, Feng-Ming Gong, Gu He, Li Yang, Xia Zhao, Xiang-Rong Song & Yu-Quan Wei. (2013) Folate-linked lipoplexes for short hairpin RNA targeting claudin-3 delivery in ovarian cancer xenografts. Journal of Controlled Release 172:3, pages 679-689.
Crossref
Bivash Mandal, Himanshu Bhattacharjee, Nivesh Mittal, Hongkee Sah, Pavan Balabathula, Laura A. Thoma & George C. Wood. (2013) Core–shell-type lipid–polymer hybrid nanoparticles as a drug delivery platform. Nanomedicine: Nanotechnology, Biology and Medicine 9:4, pages 474-491.
Crossref
Lucia M. A. Crane, Rick G. Pleijhuis, Marleen van Oosten & Gooitzen M. van Dam. 2013. Ovarian Neoplasm Imaging. Ovarian Neoplasm Imaging 479 496 .
Tracy A. Denison & You Han Bae. 2013. Cancer Targeted Drug Delivery. Cancer Targeted Drug Delivery 337 362 .
Devalingam Mahalingam & Tyler J. Curiel. 2013. Cancer Immunotherapy. Cancer Immunotherapy 335 376 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.