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Expert Opinion on Drug Delivery Volume 10, 2013 - Issue 2
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Abuse-deterrent and tamper-resistant opioids: how valuable are novel formulations in thwarting non-medical use?

Laura M LourençoMassachusetts College of Pharmacy and Health Sciences, Boston, MA, USA
, PharmD,
Michele MatthewsMassachusetts College of Pharmacy and Health Sciences, Boston, MA, USA;Harvard Medical School, Brigham & Women's Hospital, Pain Management Center, Department of Anesthesiology, Perioperative and Pain Medicine, 850 Boylston Street, Suite 320, Chestnut Hill, MA 02467, USA+1 617 732 9046; +1 617 732 9050; [email protected]
, PharmD &
Robert N JamisonHarvard Medical School, Brigham & Women's Hospital, Pain Management Center, Department of Anesthesiology, Perioperative and Pain Medicine, 850 Boylston Street, Suite 320, Chestnut Hill, MA 02467, USA+1 617 732 9046; +1 617 732 9050; [email protected]
, PhD
Pages 229-240 | Published online: 20 Dec 2012

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Maciej Gasior, Mary Bond & Richard Malamut. (2016) Routes of abuse of prescription opioid analgesics: a review and assessment of the potential impact of abuse-deterrent formulations. Postgraduate Medicine 128:1, pages 85-96.
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David J Mastropietro & Hossein Omidian. (2015) Abuse-deterrent formulations: Part 2: commercial products and proprietary technologies. Expert Opinion on Pharmacotherapy 16:3, pages 305-323.
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Michael E Schatman & Beth D Darnall. (2014) A practical and ethical solution to the opioid scheduling conundrum. Journal of Pain Research 7, pages 1-3.
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Caroline Victorri-Vigneau, Cedric Collin, Catherine Messina-Gourlot, Christel Raffournier, Michel Mallaret, Jérôme Besse, Marie-Anne Courne, Nathalie Richard, Véronique Sébille & Philippe Arnaud. (2014) Designing a tool allowing for a standardized assessment of resistance to drug diversion. Expert Opinion on Drug Delivery 11:7, pages 995-1004.
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Articles from other publishers (17)

Marc López‐Cano, Joan Font, Ester Aso, Kristoffer Sahlholm, Gisela Cabré, Jesús Giraldo, Yves De Koninck, Jordi Hernando, Amadeu Llebaria, Víctor Fernández‐Dueñas & Francisco Ciruela. (2021) Remote local photoactivation of morphine produces analgesia without opioid‐related adverse effects. British Journal of Pharmacology 180:7, pages 958-974.
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Parmita Phaugat, Suchitra Nishal & Rakhi Dhiman. (2022) Abuse-Deterrent Formulations in Constraining the Abuse Potential of Prescription Medicines: A Myth or Truth. Current Drug Delivery 19:4, pages 466-478.
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Yatan Pal Singh Balhara, Shalini Singh & Sanjay Kalra. (2020) Pragmatic Opioid Use in Painful Diabetic Neuropathy. European Endocrinology 16:1, pages 21.
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Keith Humphreys & Harold A. Pollack. 2020. The Palgrave Handbook of American Mental Health Policy. The Palgrave Handbook of American Mental Health Policy 259 295 .
Kunthel By, Jana K. McAninch, Stephine L. Keeton, Alex Secora, Cynthia J. Kornegay, Catherine S. Hwang, Thomas Ly & Mark S. Levenson. (2018) Important statistical considerations in the evaluation of post-market studies to assess whether opioids with abuse-deterrent properties result in reduced abuse in the community. Pharmacoepidemiology and Drug Safety 27:5, pages 473-478.
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Christopher M. Jones, Pradip K. Muhuri & Peter G. Lurie. (2017) Trends in the Nonmedical Use of OxyContin, United States, 2006 to 2013. The Clinical Journal of Pain 33:5, pages 452-461.
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Andreas Kimergård, Paolo Deluca, Peter Hindersson & Torben Breindahl. (2016) How Resistant to Tampering are Codeine Containing Analgesics on the Market? Assessing the Potential for Opioid Extraction. Pain and Therapy 5:2, pages 187-201.
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Howard D. Chilcoat, Paul M. Coplan, Venkatesh Harikrishnan & Louis Alexander. (2016) Decreased diversion by doctor-shopping for a reformulated extended release oxycodone product (OxyContin). Drug and Alcohol Dependence 165, pages 221-228.
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Nalini Vadivelu, Erika Schermer, Gopal Kodumudi & Jack M. Berger. (2016) The Clinical Applications of Extended-Release Abuse-Deterrent Opioids. CNS Drugs 30:7, pages 637-646.
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Carmen Walter, Claudia Knothe & Jörn Lötsch. (2015) Abuse-Deterrent Opioid Formulations: Pharmacokinetic and Pharmacodynamic Considerations. Clinical Pharmacokinetics 55:7, pages 751-767.
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Dylan C Jurcik, Ayesha H Sundaram & Robert N Jamison. (2015) Chronic pain, negative affect, and prescription opioid abuse. Current Opinion in Psychology 5, pages 42-49.
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Jeffrey Bratberg, Bill McLaughlin & Scott Brewster. (2015) Opioid overdose prevention. Journal of the American Pharmacists Association 55:5, pages 470-477.
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Icilio Cavero & Henry Holzgrefe. (2015) 14th Annual Meeting of the Safety Pharmacology Society: Threading through peripheral and central nervous system presentations. Journal of Pharmacological and Toxicological Methods 75, pages 143-157.
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Robert N. Jamison & Jianren Mao. (2015) Opioid Analgesics. Mayo Clinic Proceedings 90:7, pages 957-968.
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Grace EC Frankel. (2014) Opioid misuse in Canada and critical appraisal of aberrant behavior screening tools. World Journal of Anesthesiology 3:1, pages 61.
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Alexandra Nielsen & Wayne Wakeland. 2014. Simulation and Modeling Methodologies, Technologies and Applications. Simulation and Modeling Methodologies, Technologies and Applications 169 181 .
Esther Papaseit, Clara Pérez-Mañá, Marta Torrens & Magí Farré. (2013) Reacciones adversas de medicamentos relacionadas con el abuso y formas farmacéuticas disuasorias. Medicina Clínica 141:10, pages 454-458.
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