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Developments in delivery of medications for inner ear disease

, MD PhD & , MD
Pages 639-650 | Published online: 06 Apr 2013

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Xu Liu, Mingshuang Li, Hugh Smyth & Feng Zhang. (2018) Otic drug delivery systems: formulation principles and recent developments. Drug Development and Industrial Pharmacy 44:9, pages 1395-1408.
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Andrea Ciorba & Alessandro Martini. (2014) Regeneration in the mammalian inner ear: A glimpse into the future. Hearing, Balance and Communication 12:1, pages 1-5.
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Erdem Yildiz, Anselm J. Gadenstaetter, Matthias Gerlitz, Lukas D. Landegger, Rudolfs Liepins, Michael Nieratschker, Rudolf Glueckert, Hinrich Staecker, Clemens Honeder & Christoph Arnoldner. (2023) Investigation of inner ear drug delivery with a cochlear catheter in piglets as a representative model for human cochlear pharmacokinetics. Frontiers in Pharmacology 14.
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Goodarzi Zahra, Karami Esmaeil, Faridan Mohammad, Ali Rashidy-Pour, Mohammadi Mahdi, Akbari Mahdi & Khavanin Ali. (2022) Combined effects of the exposure to silver nanoparticles and noise on hearing function and cochlea structure of the male rats. Life Sciences 304, pages 120724.
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Zipei Zhang, Xiyu Li, Wei Zhang & Daniel S. Kohane. (2020) Drug Delivery across Barriers to the Middle and Inner Ear. Advanced Functional Materials 31:44, pages 2008701.
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Céline Jaudoin, Florence Agnely, Yann Nguyen, Evelyne Ferrary & Amélie Bochot. (2021) Nanocarriers for drug delivery to the inner ear: Physicochemical key parameters, biodistribution, safety and efficacy. International Journal of Pharmaceutics 592, pages 120038.
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Vishal Raghu, Yugandhar Ramakrishna, Robert F. Burkard & Soroush G. Sadeghi. (2020) A novel intracochlear injection method for rapid drug delivery to vestibular end organs. Journal of Neuroscience Methods 341, pages 108689.
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Manel Abbes, Karim Belharet, Hassen Mekki & Gerard Poisson. (2019) Permanent Magnets based Actuator for Microrobots Navigation. Permanent Magnets based Actuator for Microrobots Navigation.
Ryotaro Omichi, Seiji B Shibata, Cynthia C Morton & Richard J H Smith. (2019) Gene therapy for hearing loss. Human Molecular Genetics 28:R1, pages R65-R79.
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Stefanie Kennon-McGill, Melissa M. Clemens & Mitchell R. McGill. (2019) Expression of drug metabolizing enzymes and transporters in the cochlea: Implications for drug delivery and ototoxicity. Hearing Research 379, pages 98-102.
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A. I. Kryukov, N. L. Kunelskaya, E. A. Shershunova, I. E. Rebrov, V. A. Yamshchikov, E. V. Garov, G. Yu. Tsarapkin & V. V. Mishchenko. (2019) Topical drug administration to the inner ear. Modern state of the problem and development perspectives. Vestnik otorinolaringologii 84:5, pages 6.
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R. Glueckert, L. Johnson Chacko, H. Rask-Andersen, W. Liu, S. Handschuh & A. Schrott-Fischer. (2018) Anatomical basis of drug delivery to the inner ear. Hearing Research 368, pages 10-27.
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Manel Abbes, Mouna Souissi, Karim Belharet, Hassen Mekki & Gerard Poisson. (2018) A Novel Remote-Center-of-Motion Serial Manipulator for Inner Ear Drug Delivery. A Novel Remote-Center-of-Motion Serial Manipulator for Inner Ear Drug Delivery.
Lisa L. Cunningham & Debara L. Tucci. (2017) Hearing Loss in Adults. New England Journal of Medicine 377:25, pages 2465-2473.
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Chenkai Dai, Mohamed Lehar, Daniel Q. Sun, Lani Swarthout RVT, John P. Carey, Tim MacLachlan, Doug Brough, Hinrich Staecker, Alexandra M. Della Santina, Timothy E. Hullar & Charles C. Della Santina. (2017) Rhesus Cochlear and Vestibular Functions Are Preserved After Inner Ear Injection of Saline Volume Sufficient for Gene Therapy Delivery. Journal of the Association for Research in Otolaryngology 18:4, pages 601-617.
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Bradley L. Njaa. 2017. Pathologic Basis of Veterinary Disease. Pathologic Basis of Veterinary Disease 1223 1264.e1 .
S. K. Plontke, G. Götze, T. Rahne & A. Liebau. (2016) Intracochlear drug delivery in combination with cochlear implantsIntracochleäre Medikamentenapplikation in Verbindung mit Cochleaimplantaten. HNO 65:S1, pages 19-28.
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JOHNSON H. Y. CHUNG, SINA NAFICY, GORDON G. WALLACE, SINA NAFICY & STEPHEN O'LEARY. (2016) Inkjet-Printed Alginate Microspheres as Additional Drug Carriers for Injectable Hydrogels. Advances in Polymer Technology 35:4, pages 439-446.
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S. K. Plontke, G. Götze, T. Rahne & A. Liebau. (2016) Intracochleäre Medikamentenapplikation in Verbindung mit CochleaimplantatenIntracochlear drug delivery in combination with cochlear implants. HNO 64:11, pages 797-807.
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Stefan K. Plontke, Jared J. Hartsock, Ruth M. Gill & Alec N. Salt. (2016) Intracochlear Drug Injections through the Round Window Membrane: Measures to Improve Drug Retention. Audiology and Neurotology 21:2, pages 72-79.
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Hinrich Staecker, Lloyd Klickstein & Douglas E. Brough. 2016. Translational Research in Audiology, Neurotology, and the Hearing Sciences. Translational Research in Audiology, Neurotology, and the Hearing Sciences 197 217 .
Naila El Kechai, Florence Agnely, Elisabeth Mamelle, Yann Nguyen, Evelyne Ferrary & Amélie Bochot. (2015) Recent advances in local drug delivery to the inner ear. International Journal of Pharmaceutics 494:1, pages 83-101.
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Naila El Kechai, Amélie Bochot, Nicolas Huang, Yann Nguyen, Evelyne Ferrary & Florence Agnely. (2015) Effect of liposomes on rheological and syringeability properties of hyaluronic acid hydrogels intended for local injection of drugs. International Journal of Pharmaceutics 487:1-2, pages 187-196.
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Takayuki Nakagawa. (2014) Strategies for developing novel therapeutics for sensorineural hearing loss. Frontiers in Pharmacology 5.
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Anthony T. Cacace, Tom Brozoski, Bruce Berkowitz, Carol Bauer, Boris Odintsov, Magnus Bergkvist, James Castracane, Jinsheng Zhang & Avril Genene Holt. (2014) Manganese enhanced magnetic resonance imaging (MEMRI): A powerful new imaging method to study tinnitus. Hearing Research 311, pages 49-62.
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Bin Na Hong & Tong Ho Kang. (2014) Distinction between auditory electrophysiological responses in type 1 and type 2 diabetic animal models. Neuroscience Letters 566, pages 309-314.
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zahra goodarzi, esmaeil karami, Mohammad Faridan, Ali Rashidy-Pour, Mahdi mohammadi, Mehdi akbari & Ali Khavanin. (2022) Combined Effects of the Exposure to Silver Nanoparticles and Noise on Hearing Function and Cochlea Structure in Male Rats. SSRN Electronic Journal.
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