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Expert Opinion on Drug Delivery Volume 10, 2013 - Issue 5
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The future of prodrugs – design by quantum mechanics methods

Rafik KaramanAl-Quds University, Faculty of Pharmacy, Department of Bioorganic & Pharmaceutical Chemistry, P.O. Box 20002 Jerusalem, Palestine+972 2 2790413; +972 2 2790413; [email protected]
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Beesan FattashAl-Quds University, Faculty of Pharmacy, Department of Bioorganic & Pharmaceutical Chemistry, P.O. Box 20002 Jerusalem, Palestine+972 2 2790413; +972 2 2790413; [email protected]
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Alaa QtaitAl-Quds University, Faculty of Pharmacy, Department of Bioorganic & Pharmaceutical Chemistry, P.O. Box 20002 Jerusalem, Palestine+972 2 2790413; +972 2 2790413; [email protected]
Pages 713-729 | Published online: 31 Mar 2013

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Read on this site (2)

Wajd Amly & Rafik Karaman. (2016) Recent updates in utilizing prodrugs in drug delivery (2013–2015). Expert Opinion on Drug Delivery 13:4, pages 571-591.
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Rafik Karaman. (2014) Using predrugs to optimize drug candidates. Expert Opinion on Drug Discovery 9:12, pages 1405-1419.
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Articles from other publishers (14)

Nannan Wang, Yunsen Zhang, Wei Wang, Zhuyifan Ye, Hongyu Chen, Guanghui Hu & Defang Ouyang. (2023) How can machine learning and multiscale modeling benefit ocular drug development?. Advanced Drug Delivery Reviews 196, pages 114772.
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André M. de Oliveira & Mithun Rudrapal. 2022. Computer Aided Drug Design (CADD): From Ligand-Based Methods to Structure-Based Approaches. Computer Aided Drug Design (CADD): From Ligand-Based Methods to Structure-Based Approaches 1 15 .
Morteza Rezaeisadat, Nafiseh Salehi & Abdol-Khalegh Bordbar. (2021) Inclusion of Levodopa into β-Cyclodextrin: A Comprehensive Computational Study. ACS Omega 6:37, pages 23814-23825.
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Kuan-Ju Chen, Adam J. Plaunt, Franziska G. Leifer, Jeong Yeon Kang & David Cipolla. (2021) Recent advances in prodrug-based nanoparticle therapeutics. European Journal of Pharmaceutics and Biopharmaceutics 165, pages 219-243.
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Zeinab Breijyeh & Rafik Karaman. (2021) Enzyme Models—From Catalysis to Prodrugs. Molecules 26:11, pages 3248.
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Oraas Adnanhatem, Falah Shareef Abed Suhail & Amer Mousa Juda. (2020) Optimized Programs and Methods Required for the Computational Study of Beta Blockers. Journal of Physics: Conference Series 1664:1, pages 012088.
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Milica Markovic, Shimon Ben-Shabat & Arik Dahan. (2020) Computational Simulations to Guide Enzyme-Mediated Prodrug Activation. International Journal of Molecular Sciences 21:10, pages 3621.
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Martin Kotev, Laurie Sarrat & Constantino Diaz Gonzalez. 2020. Quantum Mechanics in Drug Discovery. Quantum Mechanics in Drug Discovery 231 255 .
Shalki Choudhary & Om Silakari. (2019) hCES1 and hCES2 mediated activation of epalrestat-antioxidant mutual prodrugs: Unwinding the hydrolytic mechanism using in silico approaches. Journal of Molecular Graphics and Modelling 91, pages 148-163.
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Ken Ling, Fang Men, Wei-Ci Wang, Ya-Qun Zhou, Hao-Wen Zhang & Da-Wei Ye. (2017) Carbon Monoxide and Its Controlled Release: Therapeutic Application, Detection, and Development of Carbon Monoxide Releasing Molecules (CORMs). Journal of Medicinal Chemistry 61:7, pages 2611-2635.
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Baoji Du, Dan Li, Jin Wang & Erkang Wang. (2017) Designing metal-contained enzyme mimics for prodrug activation. Advanced Drug Delivery Reviews 118, pages 78-93.
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. 2016. Bio-Targets and Drug Delivery Approaches. Bio-Targets and Drug Delivery Approaches 77 104 .
Muthukumarasamy Karthikeyan & Renu VyasMuthukumarasamy Karthikeyan & Renu Vyas. 2014. Practical Chemoinformatics. Practical Chemoinformatics 317 374 .
Rafik Karaman. (2013) Prodrugs Design Based on Inter- and Intramolecular Chemical Processes. Chemical Biology & Drug Design 82:6, pages 643-668.
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