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Improving inhaler technique, adherence to therapy and the precision of dosing: major challenges for pulmonary drug delivery

, PhD

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Read on this site (6)

Nathalie Wauthoz, Rémi Rosière & Karim Amighi. (2021) Inhaled cytotoxic chemotherapy: clinical challenges, recent developments, and future prospects. Expert Opinion on Drug Delivery 18:3, pages 333-354.
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Pieter Nicolaas Richard Dekhuijzen, Federico Lavorini & Omar S Usmani. (2016) Patients’ perspectives and preferences in the choice of inhalers: the case for Respimat® or HandiHaler®. Patient Preference and Adherence 10, pages 1561-1572.
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Timothy E Albertson, Richart Harper, Susan Murin & Christian Sandrock. (2015) Patient considerations in the treatment of COPD: focus on the new combination inhaler umeclidinium/vilanterol. Patient Preference and Adherence 9, pages 235-242.
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Mark Elphick, Dirk von Hollen, John N Pritchard, Kurt Nikander, Lucy EA Hardaker & Ross HM Hatley. (2015) Factors to consider when selecting a nebulizer for a new inhaled drug product development program. Expert Opinion on Drug Delivery 12:8, pages 1375-1387.
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Massimo Corradi, Henry Chrystyn, Borja G Cosio, Michal Pirozynski, Stelios Loukides, Renaud Louis, Monica Spinola & Omar S Usmani. (2014) NEXThaler, an innovative dry powder inhaler delivering an extrafine fixed combination of beclometasone and formoterol to treat large and small airways in asthma. Expert Opinion on Drug Delivery 11:9, pages 1497-1506.
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Articles from other publishers (41)

Popat Kumbhar, Jaskiran Kaur, Gabriele De Rubis, Keshav Raj Paudel, Parteek Prasher, Vyoma K Patel, Leander Corrie, Dinesh Kumar Chellappan, Gaurav Gupta, Sachin Kumar Singh, Vandana Patravale, John Disouza & Kamal Dua. (2023) Inhalation drug delivery in combating pulmonary infections: Advances and challenges. Journal of Drug Delivery Science and Technology 89, pages 105022.
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SURAJ CHOUDHARY & APARAJITA PATIL. (2023) AMELIORATION IN APPROACHES FOR ENHANCED PULMONARY DRUG DELIVERY. Asian Journal of Pharmaceutical and Clinical Research, pages 18-29.
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Heba Banat, Rita Ambrus & Ildikó Csóka. (2023) Drug combinations for inhalation: Current products and future development addressing disease control and patient compliance. International Journal of Pharmaceutics 643, pages 123070.
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Rocio Fernández-Parra, Pascaline Pey, Carol Reinero & Mauro Malvè. (2023) Salbutamol transport and deposition in healthy cat airways under different breathing conditions and particle sizes. Frontiers in Veterinary Science 10.
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Joshua Borris, Heather Cook, Sulgi Chae, Kathryn A. Walker & Mary Lynn McPherson. (2023) Evaluation of Peak Inspiratory Flow Rate in Hospitalized Palliative Care Patients with COPD. Pharmacy 11:4, pages 113.
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Jacqueline O’Toole, Meera Krishnan, Kristin Riekert & Michelle N. Eakin. (2022) Understanding barriers to and strategies for medication adherence in COPD: a qualitative study. BMC Pulmonary Medicine 22:1.
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Valentina Ruggiero, Rita P. Aquino, Pasquale Del Gaudio, Pietro Campiglia & Paola Russo. (2022) Post-COVID Syndrome: The Research Progress in the Treatment of Pulmonary sequelae after COVID-19 Infection. Pharmaceutics 14:6, pages 1135.
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Gao Zhen, Liu Yingying & Dong Jingcheng. (2022) Drug Therapies for COPD: A Bibliometric Review From 1980 to 2021. Frontiers in Pharmacology 13.
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Andrew R. Clark. (2022) Half a Century of Technological Advances in Pulmonary Drug Delivery: A Personal Perspective. Frontiers in Drug Delivery 2.
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Daljeet Singh Dhanjal, Parvarish Sharma, Meenu Mehta, Murtaza M Tambuwala, Parteek Prasher, Keshav R Paudel, Gang Liu, Shakti D Shukla, Philip M Hansbro, Dinesh Kumar Chellappan, Kamal Dua & Saurabh Satija. (2022) Concepts of advanced therapeutic delivery systems for the management of remodeling and inflammation in airway diseases. Future Medicinal Chemistry 14:4, pages 271-288.
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Stephen P. Newman. (2022) Fine Particle Fraction: The Good and the Bad. Journal of Aerosol Medicine and Pulmonary Drug Delivery 35:1, pages 2-10.
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Vinit V. Agnihotri, Chandrakantsing V. Pardeshi & Sanjay J. Surana. 2021. Drug Delivery Devices and Therapeutic Systems. Drug Delivery Devices and Therapeutic Systems 213 245 .
Debabrata Ghosh Dastidar, Dipanjan Ghosh, Swarnasree Ghosh & Gopal Chakrabarti. 2021. Targeting Cellular Signalling Pathways in Lung Diseases. Targeting Cellular Signalling Pathways in Lung Diseases 847 902 .
Ajay Kumar Thakur, Bharti Kaundle & Inderbir Singh. 2020. Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems. Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems 475 491 .
Brahmeshwar Mishra & Juhi Singh. 2020. Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems. Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems 57 95 .
Jeffry G. WeersYoen-Ju SonMark GluskerAlfred HaynesDaniel HuangNani KadrichuJohn LeXue LiRichard MalcolmsonDanforth P. MillerThomas E. TararaKeith UngAndy Clark. (2019) Idealhalers Versus Realhalers: Is It Possible to Bypass Deposition in the Upper Respiratory Tract?. Journal of Aerosol Medicine and Pulmonary Drug Delivery 32:2, pages 55-69.
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Wolfram Windisch, Sarah Bettina Schwarz, Friederike Sophie Magnet, Michael Dreher, Claudia Schmoor, Jan Hendrik Storre & Verena Knipel. (2018) Using web-based videos to improve inhalation technique in COPD patients requiring hospitalization: A randomized controlled trial. PLOS ONE 13:10, pages e0201188.
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Stephen P. Newman. (2018) Delivering drugs to the lungs: The history of repurposing in the treatment of respiratory diseases. Advanced Drug Delivery Reviews 133, pages 5-18.
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Sinthia Z. Bosnic-Anticevich, Biljana Cvetkovski, Elizabeth A. Azzi, Pamela Srour, Rachel Tan & Vicky Kritikos. (2018) Identifying Critical Errors: Addressing Inhaler Technique in the Context of Asthma Management. Pulmonary Therapy 4:1, pages 1-12.
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Terence E. Taylor, Yaniv Zigel, Céline De Looze, Imran Sulaiman, Richard W. Costello & Richard B. Reilly. (2018) Advances in Audio-Based Systems to Monitor Patient Adherence and Inhaler Drug Delivery. Chest 153:3, pages 710-722.
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Sinthia Zrinka Bosnic-Anticevich. (2018) Continued Innovation in Respiratory Care: The Importance of Inhaler Devices. Tuberculosis and Respiratory Diseases 81:2, pages 91.
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Nathalie Wauthoz, Ismaël Hennia, Bieke Dejaeger, Susana Ecenarro & Karim Amighi. (2017) Proposed algorithm for healthcare professionals based on product characteristics and in vitro performances in different use conditions using formoterol-based marketed products for inhalation. International Journal of Pharmaceutics 530:1-2, pages 415-429.
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Stephen P Newman. (2017) Drug delivery to the lungs: challenges and opportunities. Therapeutic Delivery 8:8, pages 647-661.
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Elizabeth Azzi, Pamela Srour, Carol Armour, Cynthia Rand & Sinthia Bosnic-Anticevich. (2017) Practice makes perfect: self-reported adherence a positive marker of inhaler technique maintenance. npj Primary Care Respiratory Medicine 27:1.
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Sven L. Klijn, Mickaël Hiligsmann, Silvia M. A. A. Evers, Miguel Román-Rodríguez, Thys van der Molen & Job F. M. van Boven. (2017) Effectiveness and success factors of educational inhaler technique interventions in asthma & COPD patients: a systematic review. npj Primary Care Respiratory Medicine 27:1.
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Paola Rogliani, Luigino Calzetta, Angelo Coppola, Francesco Cavalli, Josuel Ora, Ermanno Puxeddu, Maria Gabriella Matera & Mario Cazzola. (2017) Optimizing drug delivery in COPD: The role of inhaler devices. Respiratory Medicine 124, pages 6-14.
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. (2017) Selecting the best device to deliver inhaled chronic obstructive pulmonary disease therapy in elderly patients requires an individualized approach. Drugs & Therapy Perspectives 33:3, pages 119-123.
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Sinthia Z. Bosnic-Anticevich. (2017) Inhaler device handling: have we really started to address the problem?. European Respiratory Journal 49:2, pages 1700120.
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A. Lewis, S. Torvinen, P. N. R. Dekhuijzen, H. Chrystyn, A. T. Watson, M. Blackney & A. Plich. (2016) The economic burden of asthma and chronic obstructive pulmonary disease and the impact of poor inhalation technique with commonly prescribed dry powder inhalers in three European countries. BMC Health Services Research 16:1.
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Alexandra Lelia Dima, Marijn de Bruin & Eric Van Ganse. (2016) Mapping the Asthma Care Process: Implications for Research and Practice. The Journal of Allergy and Clinical Immunology: In Practice 4:5, pages 868-876.
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Federico Lavorini, Claudia Mannini, Elisa Chellini & Giovanni A. Fontana. (2016) Optimising Inhaled Pharmacotherapy for Elderly Patients with Chronic Obstructive Pulmonary Disease: The Importance of Delivery Devices. Drugs & Aging 33:7, pages 461-473.
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Jeffry G Weers. (2016) Enhanced design of inhaled therapeutics: what does the future hold?. Therapeutic Delivery 7:3, pages 145-148.
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Sandra R. Wilson, Meghan Halley & Sarah Knowles. 2016. Health Disparities in Respiratory Medicine. Health Disparities in Respiratory Medicine 105 133 .
Adam Bohr & Moritz Beck-Broichsitter. (2015) Generation of tailored aerosols for inhalative drug delivery employing recent vibrating-mesh nebulizer systems. Therapeutic Delivery 6:5, pages 621-636.
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Jeffry Weers. (2015) Inhaled antimicrobial therapy – Barriers to effective treatment. Advanced Drug Delivery Reviews 85, pages 24-43.
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Eckhard Beubler & Peter Dittrich. (2015) About the Therapy of Laryngotracheitis (Croup): Significance of Rectal Dosage Forms. Pharmacology 95:5-6, pages 300-302.
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Thiago Caon, Liang Jin, Cláudia M. O. Simões, Raymond S. Norton & Joseph A. Nicolazzo. (2014) Enhancing the Buccal Mucosal Delivery of Peptide and Protein Therapeutics. Pharmaceutical Research 32:1, pages 1-21.
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John N Pritchard & Rachael D Giles. (2014) Opportunities in respiratory drug delivery. Therapeutic Delivery 5:12, pages 1261-1273.
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Terence E. Taylor, Martin S. Holmes, Imran Sulaiman, Shona D'Arcy, Richard W. Costello & Richard B. Reilly. (2014) An acoustic method to automatically detect pressurized metered dose inhaler actuations. An acoustic method to automatically detect pressurized metered dose inhaler actuations.
P.N. Richard Dekhuijzen, Leif Bjermer, Federico Lavorini, Vincent Ninane, Mathieu Molimard & John Haughney. (2014) Guidance on handheld inhalers in asthma and COPD guidelines. Respiratory Medicine 108:5, pages 694-700.
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Federico Lavorini, Giovanni A. Fontana & Omar S. Usmani. (2014) New Inhaler Devices - The Good, the Bad and the Ugly. Respiration 88:1, pages 3-15.
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