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Expert Opinion on Drug Delivery Volume 11, 2014 - Issue 7
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Spray-congealed microparticles for drug delivery – an overview of factors influencing their production and characteristics

Ching Mien OhNational University of Singapore, Department of Pharmacy, GEA-NUS Pharmaceutical Processing Research Laboratory, Faculty of Science, Block S4, 18 Science Drive 4, 117543, Singapore
, BSc (Hons),
Qiyun GuoHealth Sciences Authority, 150 Cantonment Road, Cantonment Centre, Blk A, #01-02, 089762, Singapore
, PhD,
Paul Wan Sia HengNational University of Singapore, Department of Pharmacy, GEA-NUS Pharmaceutical Processing Research Laboratory, Faculty of Science, Block S4, 18 Science Drive 4, 117543, Singapore+65 6516 3506; +65 6779 1554; [email protected]
, PhD &
Lai Wah ChanNational University of Singapore, Department of Pharmacy, GEA-NUS Pharmaceutical Processing Research Laboratory, Faculty of Science, Block S4, 18 Science Drive 4, 117543, Singapore+65 6516 3506; +65 6779 1554; [email protected]
, PhD
Pages 1047-1060 | Published online: 22 May 2014

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Hongyi Ouyang, Soon Jun Ang, Zong Yang Lee, Tze Ning Hiew, Paul Wan Sia Heng & Lai Wah Chan. (2022) Effect of drug load and lipid–wax blends on drug release and stability from spray-congealed microparticles. Pharmaceutical Development and Technology 27:10, pages 1069-1082.
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Articles from other publishers (12)

Archana Mahapatra, Sharmila Patil & Jyoti Dhakane-Lad. 2024. Handbook of Nutraceuticals. Handbook of Nutraceuticals 1 21 .
Alessandro Candiani, Andrea Milanesi, Andrea Foglio Bonda, Giada Diana, Elia Bari, Lorena Segale, Maria Luisa Torre & Lorella Giovannelli. (2022) Solid Lipid Microparticles by Spray Congealing of Water/Oil Emulsion: An Effective/Versatile Loading Strategy for a Highly Soluble Drug. Pharmaceutics 14:12, pages 2805.
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Serena Bertoni, Dritan Hasa, Beatrice Albertini, Beatrice Perissutti, Mario Grassi, Dario Voinovich & Nadia Passerini. (2022) Better and greener: sustainable pharmaceutical manufacturing technologies for highly bioavailable solid dosage forms. Drug Delivery and Translational Research 12:8, pages 1843-1858.
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Jayne de Abreu Figueiredo, Carlos Ramon de Paula Silva, Matheus Felipe Souza Oliveira, Laís Bruno Norcino, Pedro Henrique Campelo, Diego Alvarenga Botrel & Soraia Vilela Borges. (2022) Microencapsulation by spray chilling in the food industry: Opportunities, challenges, and innovations. Trends in Food Science & Technology 120, pages 274-287.
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Serena Bertoni, Beatrice Albertini, Joanna Ronowicz-Pilarczyk, Natalia Calonghi & Nadia Passerini. (2021) Solvent-Free Fabrication of Biphasic Lipid-Based Microparticles with Tunable Structure. Pharmaceutics 14:1, pages 54.
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Hongyi Ouyang, Chen Yee Ang, Paul Wan Sia Heng & Lai Wah Chan. (2019) Effects of Drug Particle Size and Lipid Additives on Drug Release from Paraffin Wax Formulations Prepared by Spray Congealing Technique. AAPS PharmSciTech 20:7.
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Serena Bertoni, Beatrice Albertini & Nadia Passerini. (2019) Spray Congealing: An Emerging Technology to Prepare Solid Dispersions with Enhanced Oral Bioavailability of Poorly Water Soluble Drugs. Molecules 24:19, pages 3471.
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Serena Bertoni, Luisa S Dolci, Beatrice Albertini & Nadia Passerini. (2018) Spray congealing: a versatile technology for advanced drug-delivery systems. Therapeutic Delivery 9:11, pages 833-845.
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Vivian Boesso Oriani, Izabela Dutra Alvim, Bruno Nicolau Paulino, Fernanda Ramalho Procópio, Glaucia Maria Pastore & Míriam Dupas Hubinger. (2018) The influence of the storage temperature on the stability of lipid microparticles containing ginger oleoresin. Food Research International 109, pages 472-480.
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Luisa Duque, Martin Körber & Roland Bodmeier. (2018) Impact of change of matrix crystallinity and polymorphism on ovalbumin release from lipid-based implants. European Journal of Pharmaceutical Sciences 117, pages 128-137.
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Claudia Engelmann & Udo Kragl. (2018) Spray congealing as innovative technique for enzyme encapsulation. Journal of Chemical Technology & Biotechnology 93:1, pages 191-197.
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Ching Mien Oh, Paul Wan Sia Heng & Lai Wah Chan. (2014) A Study on the Impact of Hydroxypropyl Methylcellulose on the Viscosity of PEG Melt Suspensions Using Surface Plots and Principal Component Analysis. AAPS PharmSciTech 16:2, pages 466-477.
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