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ABCB1 and ABCG2 expression in the placenta and fetus: an interspecies comparison

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Pages 1385-1398 | Published online: 26 Aug 2010

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Lyrialle W. Han, Chunying Gao & Qingcheng Mao. (2018) An update on expression and function of P-gp/ABCB1 and BCRP/ABCG2 in the placenta and fetus. Expert Opinion on Drug Metabolism & Toxicology 14:8, pages 817-829.
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Rebecca Schnepf & Oliver Zolk. (2013) Effect of the ATP-binding cassette transporter ABCG2 on pharmacokinetics: experimental findings and clinical implications. Expert Opinion on Drug Metabolism & Toxicology 9:3, pages 287-306.
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Melanie A. Felmlee & Qing Zhang. 2022. Drug Transporters. Drug Transporters 393 412 .
Michael D. Reed & Donald R. Mattison. 2022. Clinical Pharmacology During Pregnancy. Clinical Pharmacology During Pregnancy 79 92 .
Francesco Traccis, Valeria Serra, Claudia Sagheddu, Mauro Congiu, Pierluigi Saba, Gabriele Giua, Paola Devoto, Roberto Frau, Joseph Francois Cheer & Miriam Melis. (2021) Prenatal THC Does Not Affect Female Mesolimbic Dopaminergic System in Preadolescent Rats. International Journal of Molecular Sciences 22:4, pages 1666.
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Thomas Efferth, Onat Kadioglu, Mohamed E. M. Saeed, Ean-Jeong Seo, Armelle T. Mbaveng & Victor Kuete. (2020) Medicinal plants and phytochemicals against multidrug-resistant tumor cells expressing ABCB1, ABCG2, or ABCB5: a synopsis of 2 decades. Phytochemistry Reviews 20:1, pages 7-53.
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Carolina Rocha-Pereira, Carolina I. Ghanem, Renata Silva, Alfredo G. Casanova, Margarida Duarte-Araújo, Salomé Gonçalves-Monteiro, Emília Sousa, Maria de Lourdes Bastos & Fernando Remião. (2020) P-glycoprotein activation by 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5) in rat distal ileum: ex vivo and in vivo studies. Toxicology and Applied Pharmacology 386, pages 114832.
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Lenka Tupova, Martina Ceckova, Csilla Ambrus, Ales Sorf, Zuzana Ptackova, Zsuzsanna Gaborik & Frantisek Staud. (2019) Interactions between Maraviroc and the ABCB1, ABCG2, and ABCC2 Transporters: An Important Role in Transplacental Pharmacokinetics. Drug Metabolism and Disposition 47:9, pages 954-960.
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Changqing Tang, Chunyan Luo, Yimin Hua, Kaiyu Zhou, Hongyu Duan, Fan Ma, Yi Zhang, Yifei Li, Dajian Qiu & Chuan Wang. (2019) Placental P-glycoprotein inhibition enhances susceptibility to Di-(2-ethylhexyl)-phthalate induced cardiac malformations in mice: A possibly promising target for congenital heart defects prevention. PLOS ONE 14:5, pages e0214873.
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Milan Hano, Lenka Tomášová, Mário Šereš, Lucia Pavlíková, Albert Breier & Zdena Sulová. (2018) Interplay between P-Glycoprotein Expression and Resistance to Endoplasmic Reticulum Stressors. Molecules 23:2, pages 337.
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Thomas Efferth & Manfred Volm. (2017) Multiple resistance to carcinogens and xenobiotics: P-glycoproteins as universal detoxifiers. Archives of Toxicology 91:7, pages 2515-2538.
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Anand A. Joshi, Soniya S. Vaidya, Marie V. St-Pierre, Andrei M. Mikheev, Kelly E. Desino, Abner N. Nyandege, Kenneth L. Audus, Jashvant D. Unadkat & Phillip M. Gerk. (2016) Placental ABC Transporters: Biological Impact and Pharmaceutical Significance. Pharmaceutical Research 33:12, pages 2847-2878.
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Martha L. Bustos, Yang Zhao, Huijun Chen, Steve N. Caritis & Raman Venkataramanan. (2016) Polymorphisms in CYP1A1 and CYP3A5 Genes Contribute to the Variability in Granisetron Clearance and Exposure in Pregnant Women with Nausea and Vomiting . Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 36:12, pages 1238-1244.
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Graham J. Burton, Abigail L. Fowden & Kent L. Thornburg. (2016) Placental Origins of Chronic Disease. Physiological Reviews 96:4, pages 1509-1565.
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Lili Liu, Liang Zhou, Shuiwang Hu, Shanyu Zhou, Yingyu Deng, Ming Dong, Jianxun Huang, Yuli Zeng, Xiaoyan Chen, Na Zhao, Hongling Li & Zhenhua Ding. (2016) Down-regulation of ABCG2 and ABCB4 transporters in the placenta of rats exposed to cadmium. Oncotarget 7:25, pages 38154-38163.
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Yaqiong Zu, Zhiyong Yang, Songshan Tang, Ying Han & Jun Ma. (2014) Effects of P-Glycoprotein and Its Inhibitors on Apoptosis in K562 Cells. Molecules 19:9, pages 13061-13075.
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Valeria Feinshtein, Offer Erez, Zvi Ben-Zvi, Tamar Eshkoli, Boaz Sheizaf, Eyal Sheiner & Gershon Holcberg. (2013) Cannabidiol enhances xenobiotic permeability through the human placental barrier by direct inhibition of breast cancer resistance protein: an ex vivo study. American Journal of Obstetrics and Gynecology 209:6, pages 573.e1-573.e15.
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Valeria Feinshtein, Offer Erez, Zvi Ben-Zvi, Noam Erez, Tamar Eshkoli, Boaz Sheizaf, Eyal Sheiner, Mahmud Huleihel & Gershon Holcberg. (2013) Cannabidiol changes P-gp and BCRP expression in trophoblast cell lines. PeerJ 1, pages e153.
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Pritam Sahota, James Popp, Jerry Hardisty & Chirukandath GopinathDavid Christ. 2013. Toxicologic Pathology. Toxicologic Pathology 55 76 .
Michael D. Reed & Donald R. Mattison. 2013. Clinical Pharmacology During Pregnancy. Clinical Pharmacology During Pregnancy 73 87 .
G Moreno-Sanz, O Sasso, A Guijarro, O Oluyemi, R Bertorelli, A Reggiani & D Piomelli. (2012) Pharmacological characterization of the peripheral FAAH inhibitor URB937 in female rodents: interaction with the Abcg2 transporter in the blood-placenta barrier. British Journal of Pharmacology 167:8, pages 1620-1628.
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M. Kummu, E. Sieppi, K. Wallin, A. Rautio, K. V?h?kangas & P. Myllynen. (2012) Cadmium inhibits ABCG2 transporter function in BeWo choriocarcinoma cells and MCF-7 cells overexpressing ABCG2. Placenta 33:10, pages 859-865.
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