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Expert Opinion on Drug Metabolism & Toxicology Volume 9, 2013 - Issue 6
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Metabolic and toxicological considerations of the opioid replacement therapy and analgesic drugs: methadone and buprenorphine

David E MoodyUniversity of Utah College of Pharmacy, Department of Pharmacology and Toxicology, 417 Wakara Way, Suite 2111, Salt Lake City, Utah, UT 84108, USA+1 801 581 5117; +1 801 581 5034; [email protected]
, PhD (Associate Director Center for Human Toxicology, Research Professor)
Pages 675-697 | Published online: 29 Mar 2013

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Ricardo Jorge Dinis-Oliveira. (2016) Metabolomics of methadone: clinical and forensic toxicological implications and variability of dose response. Drug Metabolism Reviews 48:4, pages 568-576.
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Juliusz Kosel, Piotr Bobik & Michał Tomczyk. (2016) Buprenorphine – the unique opioid adjuvant in regional anesthesia. Expert Review of Clinical Pharmacology 9:3, pages 375-383.
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Jon Andsnes Berg, Jan Schjøtt, Kjell O Fossan & Bettina Riedel. (2015) Cross-reactivity of the CEDIA buprenorphine assay in drugs-of-abuse screening: influence of dose and metabolites of opioids. Substance Abuse and Rehabilitation 6, pages 131-139.
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Michael Soyka. (2015) New developments in the management of opioid dependence: focus on sublingual buprenorphine–naloxone. Substance Abuse and Rehabilitation 6, pages 1-14.
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Articles from other publishers (13)

Eve Allen, Sona Samadian, Gary Altobelli, Jacinta Johnson & Chris Holmwood. (2023) Exploring patient experience and satisfaction with depot buprenorphine formulations: A mixed‐methods study. Drug and Alcohol Review 42:4, pages 791-802.
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Mina Ansari, Yasna Rostam-Abadi, Shahab Baheshmat, Marziyeh Hamzehzadeh, Jaleh Gholami, Ramin Mojtabai & Afarin Rahimi-Movaghar. (2021) Buprenorphine abuse and health risks in Iran: A systematic review. Drug and Alcohol Dependence 226, pages 108871.
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Amanda M. Raines, Nicholas P. Allan, Shelby J. McGrew, Caroline V. Gooch, Marie Wyatt, C. Laurel Franklin & Norman B. Schmidt. (2020) A computerized anxiety sensitivity intervention for opioid use disorders: A pilot investigation among veterans. Addictive Behaviors 104, pages 106285.
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J.A. Jeevendra MartynJianren MaoEdward A. Bittner. (2019) Opioid Tolerance in Critical Illness. New England Journal of Medicine 380:4, pages 365-378.
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Renée J. G. Arnold, Jun Tang, Joshua Schrecker & Cheryl Hild. (2018) Impact of Definitive Drug–Drug Interaction Testing on Medication Management and Patient Care. Drugs - Real World Outcomes 5:4, pages 217-224.
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Janet K. Coller, Daniel T. Barratt & Andrew A. Somogyi. 2016. Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents. Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents 565 577 .
T Lewis, J Dinh & JS Leeder. (2015) Genetic determinants of fetal opiate exposure and risk of neonatal abstinence syndrome: Knowledge deficits and prospects for future research. Clinical Pharmacology & Therapeutics 98:3, pages 309-320.
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Mimi Stokke Opdal, Margrete Arnesen, Lill Dannevig Müller, Ingunn Hullstein, Karim Sayed, Odd Brørs, Marianne Kringen, Solbjørg Sagedal, Knut Gjesdal & Peter Krajci. (2015) Effects of Hemodialysis on Methadone Pharmacokinetics and QTc. Clinical Therapeutics 37:7, pages 1594-1599.
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Chee M. Ng, Erin Dombrowsky, Hopi Lin, Michelle E. Erlich, David E. Moody, Jeffrey S. Barrett & Walter K. Kraft. (2015) Population Pharmacokinetic Model of Sublingual Buprenorphine in Neonatal Abstinence Syndrome. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 35:7, pages 670-680.
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David E. Moody, Fenyun Liu & Wenfang B. Fang. (2015) Azole Antifungal Inhibition of Buprenorphine, Methadone and Oxycodone In Vitro Metabolism. Journal of Analytical Toxicology 39:5, pages 374-386.
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John F. Carlquist, David E. Moody, Stacey Knight, Eric G. Johnson, Wenfang B. Fang, John A. Huntinghouse, Jeffrey S. Rollo, Lynn R. Webster & Jeffrey L. Anderson. (2015) A Possible Mechanistic Link Between the CYP2C19 Genotype, the Methadone Metabolite Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidene (EDDP), and Methadone-Induced Corrected QT Interval Prolongation in a Pilot Study. Molecular Diagnosis & Therapy 19:2, pages 131-138.
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Deborah French. (2013) The challenges of LC–MS/MS analysis of opiates and opioids in urine. Bioanalysis 5:22, pages 2803-2820.
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D. E. Moody, F. Liu & W. B. Fang. (2013) In vitro Inhibition of Methadone and Oxycodone Cytochrome P450-Dependent Metabolism: Reversible Inhibition by H2-Receptor Agonists and Proton-Pump Inhibitors. Journal of Analytical Toxicology 37:8, pages 476-485.
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