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Expert Opinion on Drug Metabolism & Toxicology Volume 9, 2013 - Issue 9
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In vitro approaches to investigate cytochrome P450 activities: update on current status and their applicability

Chin Eng OngMonash University Sunway Campus, Jeffrey Cheah School of Medicine and Health Sciences, Jalan Lagoon Selatan, 46150 Bandar Sunway, Selangor, Malaysia+603 551 44918; [email protected]
, PhD,
Yan PanInternational Medical University, School of Medical Sciences, 126, Jalan Jalil Perkasa 19, Bukit Jalil, 57000 Kuala Lumpur, Malaysia
, PhD,
Joon Wah MakInternational Medical University, School of Medical Sciences, 126, Jalan Jalil Perkasa 19, Bukit Jalil, 57000 Kuala Lumpur, Malaysia
&
Rusli IsmailUniversiti Sains Malaysia, Institute for Research in Molecular Medicine, Pharmacogenetics Research Group, 16150 Kubang Kerian, Kelantan, Malaysia
Pages 1097-1113 | Published online: 17 May 2013

Citations (10)

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Read on this site (2)

Yan Pan & Eng Chin Ong. (2017) Cytochrome P450 2W1 (CYP2W1) – ready for use as the biomarker and drug target for cancer?. Xenobiotica 47:10, pages 923-932.
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Danyi Lu, Dong Dong, Zhong Liu, Yifei Wang & Baojian Wu. (2015) Metabolism elucidation of BJ-B11 (a heat shock protein 90 inhibitor) by human liver microsomes: identification of main contributing enzymes. Expert Opinion on Drug Metabolism & Toxicology 11:7, pages 1029-1040.
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Articles from other publishers (8)

Boon Hooi Tan, Yan Pan, Uma Devi Palanisamy, Iekhsan Othman, Nafees Ahmed, Beow Chin Yap & Chin Eng Ong. (2019) Expression of cytochrome P450 2C9 (CYP2C9) in Escherichia coli and its functional characterization. Asia Pacific Journal of Molecular Biology and Biotechnology, pages 43-55.
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Michele Gottardi & Nina Cedergreen. (2019) The synergistic potential of azole fungicides does not directly correlate to the inhibition of cytochrome P450 activity in aquatic invertebrates. Aquatic Toxicology 207, pages 187-196.
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Francisco Esteves, Diana Campelo, Philippe Urban, Sophie Bozonnet, Thomas Lautier, José Rueff, Gilles Truan & Michel Kranendonk. (2018) Human cytochrome P450 expression in bacteria: Whole-cell high-throughput activity assay for CYP1A2, 2A6 and 3A4. Biochemical Pharmacology 158, pages 134-140.
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David M. Burger, Lindsey H. M. te Brake & Rob E. Aarnoutse. 2018. Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions. Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions 15 47 .
Michele Gottardi, Andreas Kretschmann & Nina Cedergreen. (2015) Measuring cytochrome P450 activity in aquatic invertebrates: a critical evaluation of in vitro and in vivo methods. Ecotoxicology 25:2, pages 419-430.
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Iwona Wilk-Zasadna, Camilla Bernasconi, Olavi Pelkonen & Sandra Coecke. (2015) Biotransformation in vitro: An essential consideration in the quantitative in vitro-to-in vivo extrapolation (QIVIVE) of toxicity data. Toxicology 332, pages 8-19.
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Xinwen Wang, Hao-Jie Zhu, Juliana Munoz, Bill J. Gurley & John S. Markowitz. (2015) An ex vivo approach to botanical–drug interactions: A proof of concept study. Journal of Ethnopharmacology 163, pages 149-156.
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Hui Xin Ong, Daniela Traini, Giulia Ballerin, Lucy Morgan, Lachlan Buddle, Santo Scalia & Paul M. Young. (2014) Combined Inhaled Salbutamol and Mannitol Therapy for Mucus Hyper-secretion in Pulmonary Diseases. The AAPS Journal 16:2, pages 269-280.
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