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Hepatobiliary transporters in drug-induced cholestasis: a perspective on the current identifying tools

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Neel Deferm, Tom De Vocht, Bing Qi, Pieter Van Brantegem, Eva Gijbels, Mathieu Vinken, Peter de Witte, Thomas Bouillon & Pieter Annaert. (2019) Current insights in the complexities underlying drug-induced cholestasis. Critical Reviews in Toxicology 49:6, pages 520-548.
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Petar D. Petrov, M. Leonor Fernández-Murga, Mireia López-Riera, M. José Goméz-Lechón, Jose V. Castell & Ramiro Jover. (2018) Predicting drug-induced cholestasis: preclinical models. Expert Opinion on Drug Metabolism & Toxicology 14:7, pages 721-738.
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Lisa Chedik, Arnaud Bruyere, Astrid Bacle, Sophie Potin, Marc Le Vée & Olivier Fardel. (2018) Interactions of pesticides with membrane drug transporters: implications for toxicokinetics and toxicity. Expert Opinion on Drug Metabolism & Toxicology 14:7, pages 739-752.
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Ágnes Telbisz & László Homolya. (2016) Recent advances in the exploration of the bile salt export pump (BSEP/ABCB11) function. Expert Opinion on Therapeutic Targets 20:4, pages 501-514.
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M. Teresa Donato, Gloria Gallego-Ferrer & Laia Tolosa. (2022) In Vitro Models for Studying Chronic Drug-Induced Liver Injury. International Journal of Molecular Sciences 23:19, pages 11428.
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Juyang Huang, Qin Wang, Mengying Chen, Yanan Bi, Hong Shi & Kun Zhou. (2020) Effects of psoralen on hepatic bile acid transporters in rats. Human & Experimental Toxicology 40:6, pages 1012-1021.
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Y Yang, L Liu, M Xu, X Zhang, L Wang, Q He, M Xu & X Jiang. (2020) Tanshinone ⅡA may alleviate rifampin-induced cholestasis by regulating the expression and function of NTCP. Human & Experimental Toxicology 40:6, pages 1003-1011.
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Yi-Shin Huang, Tien-En Chang, Chin-Lin Perng & Yi-Hsiang Huang. (2021) The association of transporter ABCC2 (MRP2) genetic variation and drug-induced hyperbilirubinemia. Journal of the Chinese Medical Association 84:2, pages 129-135.
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Yujie Yang, Lei Liu, Xiqian Zhang, Xuehua Jiang & Ling Wang. (2019) Tanshinone IIA prevents rifampicin‐induced liver injury by regulating BSEP/NTCP expression via epigenetic activation of NRF2. Liver International 40:1, pages 141-154.
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Carolin Lackner & Alexander S. Knisely. 2020. Pathologie. Pathologie 63 116 .
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Maria Fotoulaki, Styliani Giza, Milan JirsaTassos Grammatikopoulos, Rosa Miquel, Prodromos Hytiroglou, Ioannis TsitouridisA.S. Knisely. (2019) Beyond an Obvious Cause of Cholestasis in a Toddler: Compound Heterozygosity for ABCB11 Mutations . Pediatrics 143:5.
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Eva Gijbels, Vânia Vilas-Boas, Neel Deferm, Lindsey Devisscher, Hartmut Jaeschke, Pieter Annaert & Mathieu Vinken. (2019) Mechanisms and in vitro models of drug-induced cholestasis. Archives of Toxicology 93:5, pages 1169-1186.
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Tea Omanović Kolarić, Vjera Ninčević, Robert Smolić, Martina Smolić & George Y Wu. (2019) Mechanisms of Hepatic Cholestatic Drug Injury. Journal of Clinical and Translational Hepatology 7:X, pages 1-7.
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Stef De Lombaerde, Sara Neyt, Christian Vanhove & Filip De Vos. 2019. Experimental Cholestasis Research. Experimental Cholestasis Research 87 98 .
Eva Gijbels & Mathieu Vinken. 2019. Experimental Cholestasis Research. Experimental Cholestasis Research 1 14 .
M. Leonor Fernández-Murga, Petar D. Petrov, Isabel Conde, Jose V. Castell, M. José Goméz-Lechón & Ramiro Jover. (2018) Advances in drug-induced cholestasis: Clinical perspectives, potential mechanisms and in vitro systems. Food and Chemical Toxicology 120, pages 196-212.
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Nayana George, Minjun Chen, Nancy Yuen, Christine M. Hunt & Ayako Suzuki. (2018) Interplay of gender, age and drug properties on reporting frequency of drug-induced liver injury. Regulatory Toxicology and Pharmacology 94, pages 101-107.
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Stef De Lombaerde, Ken Kersemans, Sara Neyt, Jeroen Verhoeven, Christian Vanhove & Filip De Vos. (2018) Evaluating Hepatobiliary Transport with 18 F-Labeled Bile Acids: The Effect of Radiolabel Position and Bile Acid Structure on Radiosynthesis and In Vitro and In Vivo Performance . Contrast Media & Molecular Imaging 2018, pages 1-9.
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Yi-Fei Li, Jia-Sheng Wu, Yuan-Yuan Li, Yan Dai, Min Zheng, Jia-Kai Zeng, Guo-Feng Wang, Tian-Ming Wang, Wen-Kai Li, Xue-Yan Zhang, Ming Gu, Cheng Huang, Li Yang, Zheng-Tao Wang & Yue-Ming Ma. (2017) Chicken bile powder protects against α-naphthylisothiocyanate-induced cholestatic liver injury in mice. Oncotarget 8:57, pages 97137-97152.
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Stef De Lombaerde, Sara Neyt, Ken Kersemans, Jeroen Verhoeven, Lindsey Devisscher, Hans Van Vlierberghe, Christian Vanhove & Filip De Vos. (2017) Synthesis, in vitro and in vivo evaluation of 3?-[18F]fluorocholic acid for the detection of drug-induced cholestasis in mice. PLOS ONE 12:3, pages e0173529.
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Gerhard F. Ecker. 2017. Transporters as Drug Targets. Transporters as Drug Targets 107 118 .
Luisa Pozzo, Andrea Vornoli, Ilaria Coppola, Clara Maria Della Croce, Lucia Giorgetti, Pier Giovanni Gervasi & Vincenzo Longo. (2016) Effect of HFD/STZ on expression of genes involved in lipid, cholesterol and glucose metabolism in rats. Life Sciences 166, pages 149-156.
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Zainab M. Mahdi, Uta Synal-Hermanns, Aylin Yoker, Kaspar P. Locher & Bruno Stieger. (2016) Role of Multidrug Resistance Protein 3 in Antifungal-Induced Cholestasis. Molecular Pharmacology 90:1, pages 23-34.
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Houfu Liu & Jasminder Sahi. (2016) Role of Hepatic Drug Transporters in Drug Development. The Journal of Clinical Pharmacology 56, pages S11-S22.
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Stefanie D. Krämer, Hélène E. Aschmann, Maja Hatibovic, Katharina F. Hermann, Claudia S. Neuhaus, Cyrill Brunner & Sara Belli. (2016) When barriers ignore the “rule-of-five”. Advanced Drug Delivery Reviews 101, pages 62-74.
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