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Drug Evaluations

Pharmacokinetic evaluation of fingolimod for the treatment of multiple sclerosis

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Laura Dumitrescu, Athanasios Papathanasiou, Catalina Coclitu, Afagh Garjani, Nikos Evangelou, Cris S. Constantinescu, Bogdan Ovidiu Popescu & Radu Tanasescu. (2023) An update on the use of sphingosine 1-phosphate receptor modulators for the treatment of relapsing multiple sclerosis. Expert Opinion on Pharmacotherapy 24:4, pages 495-509.
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Katja Thomas, Undine Proschmann & Tjalf Ziemssen. (2017) Fingolimod hydrochloride for the treatment of relapsing remitting multiple sclerosis. Expert Opinion on Pharmacotherapy 18:15, pages 1649-1660.
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Catalina Coclitu, Cris S. Constantinescu & Radu Tanasescu. (2016) The future of multiple sclerosis treatments. Expert Review of Neurotherapeutics 16:12, pages 1341-1356.
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Emanuele D’Amico, Carmela Leone, Cinzia Caserta & Francesco Patti. (2015) Oral drugs in multiple sclerosis therapy: an overview and a critical appraisal. Expert Review of Neurotherapeutics 15:7, pages 803-824.
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Articles from other publishers (8)

Elissa M. Milford, Lara Meital, Anna Kuballa, Michael C. Reade & Fraser D. Russell. (2022) Fingolimod does not prevent syndecan-4 shedding from the endothelial glycocalyx in a cultured human umbilical vein endothelial cell model of vascular injury. Intensive Care Medicine Experimental 10:1.
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Claudia Fracasso, Alice Passoni, Laura Brambilla, Renato Mantegazza, Silvia Rossi, Marco Gobbi & Jacopo Lucchetti. (2022) A Validated HPLC-MS/MS Method for Quantification of Fingolimod and Fingolimod-Phosphate in Human Plasma: Application to Patients with Relapsing–Remitting Multiple Sclerosis. Applied Sciences 12:12, pages 6102.
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Amnon A. Berger, Emily R. Sottosanti, Ariel Winnick, Jonathan Izygon, Kevin Berardino, Elyse M. Cornett, Alan D. Kaye, Giustino Varrassi, Omar Viswanath & Ivan Urits. (2021) Monomethyl Fumarate (MMF, Bafiertam) for the Treatment of Relapsing Forms of Multiple Sclerosis (MS). Neurology International 13:2, pages 207-223.
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Noelyn Anne Hung, Fernando Guillermo Costa, Cheung‐Tak Hung & Mónica Esther Rosenberg. (2020) Bioequivalence Study of 2 Capsule Formulations of Fingolimod 0.5 mg Assessing Both Parent Drug and Active Metabolite in New Zealand Healthy Subjects (Truncated Design). Clinical Pharmacology in Drug Development 9:5, pages 610-620.
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Claudia Mara Ribeiro, Sayonara Rangel Oliveira, Daniela Frizon Alfieri, Tamires Flauzino, Damacio Ramón Kaimen-Maciel, Andréa Name Colado Simão, Michael Maes & Edna Maria Vissoci Reiche. (2019) Tumor necrosis factor alpha (TNF-α) and its soluble receptors are associated with disability, disability progression and clinical forms of multiple sclerosis. Inflammation Research 68:12, pages 1049-1059.
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Mehrdad Gholamzad, Masoumeh Ebtekar, Mehdi Shafiee Ardestani, Maryam Azimi, Zeinab Mahmodi, Mohammad Javad Mousavi & Saeed Aslani. (2018) A comprehensive review on the treatment approaches of multiple sclerosis: currently and in the future. Inflammation Research 68:1, pages 25-38.
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Sophie Steeland, Sara Van Ryckeghem, Griet Van Imschoot, Riet De Rycke, Wendy Toussaint, Leen Vanhoutte, Christian Vanhove, Filip De Vos, Roosmarijn E. Vandenbroucke & Claude Libert. (2017) TNFR1 inhibition with a Nanobody protects against EAE development in mice. Scientific Reports 7:1.
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Nicola De Stefano, Diego G. Silva & Michael H. Barnett. (2017) Effect of Fingolimod on Brain Volume Loss in Patients with Multiple Sclerosis. CNS Drugs 31:4, pages 289-305.
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