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Expert Opinion on Drug Metabolism & Toxicology Volume 10, 2014 - Issue 7

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The role of formulation on the pharmacokinetics of antiretroviral drugs

Diane ET BastiaansRadboud University Nijmegen Medical Centre, Department of Pharmacy, Nijmegen, The Netherlands+31 24 3616405; +31 24 3668755; [email protected]

, PharmD,

Tim R CresseyChiang Mai University, Program for HIV Prevention and Treatment (IRD URI 174), Department of Medical Technology, Chiang Mai, Thailand;Harvard School of Public Health, Boston, MA, USA

, PhD (Faculty of Associated Medical Sciences) ,

Herman VromansUtrecht University, Utrecht Institute for Pharmaceutical Sciences (UIPS), Department of Pharmaceutics, Utrecht, The Netherlands

, PharmD PhD &

David M BurgerRadboud University Nijmegen Medical Centre, Department of Pharmacy, Nijmegen, The Netherlands+31 24 3616405; +31 24 3668755; [email protected]

, PharmD PhD

Pages 1019-1037 | Published online: 30 May 2014

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https://doi.org/10.1517/17425255.2014.925879
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Shaghayegh Mohsenian Naghani, Mark MPM Jansen, Tessa Jaspers, Diane Bastiaans & David Burger. (2023) Crushing lopinavir/ritonavir tablets does not result in lower exposure to lopinavir/ritonavir in adult patients with COVID-19. European Journal of Hospital Pharmacy 30:e1, pages e106-e108.
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Anne M. Schijvens, Saskia N. de Wildt, Elisabeth A. M. Cornelissen, Fransje H. S. van Hesteren, Michiel F. Schreuder & Rob ter Heine. (2020) Low Bioavailability of Oral Tacrolimus Suspension in Pediatric Kidney Transplant Patients. Clinical Pharmacokinetics 59:11, pages 1483-1485.
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Anna Halling Folkmar Andersen & Martin Tolstrup. (2020) The Potential of Long-Acting, Tissue-Targeted Synthetic Nanotherapy for Delivery of Antiviral Therapy Against HIV Infection. Viruses 12:4, pages 412.
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Dario CattaneoSara BaldelliValeria CozziEmilio ClementiDeborah J. E. Marriott & Cristina Gervasoni. (2020) Impact of Therapeutic Drug Monitoring of Antiretroviral Drugs in Routine Clinical Management of People Living With HIV: A Narrative Review. Therapeutic Drug Monitoring 42:1, pages 64-74.
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Oluwatomide Adeoye, Jaime Conceição, Patrícia A. Serra, Andreia Bento da Silva, Noélia Duarte, Rita C. Guedes, Marta C. Corvo, Ana Aguiar-Ricardo, László Jicsinszky, Teresa Casimiro & Helena Cabral-Marques. (2020) Cyclodextrin solubilization and complexation of antiretroviral drug lopinavir: In silico prediction; Effects of derivatization, molar ratio and preparation method. Carbohydrate Polymers 227, pages 115287.
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Stephen E. Gerrard, Jennifer Walsh, Niya Bowers, Smita Salunke & Susan Hershenson. (2019) Innovations in Pediatric Drug Formulations and Administration Technologies for Low Resource Settings. Pharmaceutics 11:10, pages 518.
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Anthony J. Garcia-Prats, Susan E. Purchase, Muhammad Osman, Heather R. Draper, H. Simon Schaaf, Lubbe Wiesner, Paolo Denti & Anneke C. Hesseling. (2019) Pharmacokinetics, Safety, and Dosing of Novel Pediatric Levofloxacin Dispersible Tablets in Children with Multidrug-Resistant Tuberculosis Exposure. Antimicrobial Agents and Chemotherapy 63:4.
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Sai Archana Krovi, Matthew D. Gallovic, Austin M. Keller, Menakshi Bhat, Pamela Tiet, Naihan Chen, Michael A. Collier, Elizabeth G. Gurysh, Erica N. Pino, Monica M. Johnson, M. Shamim Hasan Zahid, Mackenzie L. Cottrell, Jason R. Pirone, Angela D. Kashuba, Jesse J. Kwiek, Eric M. Bachelder & Kristy M. Ainslie. (2018) Injectable long-acting human immunodeficiency virus antiretroviral prodrugs with improved pharmacokinetic profiles. International Journal of Pharmaceutics 552:1-2, pages 371-377.
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Diane E. T. Bastiaans, Sibyl P. M. Geelen, Eline G. Visser, Michiel van der Flier, Clementien L. Vermont, Angela P. H. Colbers, Monique Roukens, David M. Burger & Annemarie M. C. van Rossum. (2018) Pharmacokinetics, Short-term Safety and Efficacy of the Approved Once-daily Darunavir/Ritonavir Dosing Regimen in HIV-infected Children. Pediatric Infectious Disease Journal 37:10, pages 1008-1010.
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Kimberly Adkison, Allen Wolstenholme, Yu Lou, Zhiping Zhang, Amy Eld, Teodora Perger, Harald Vangerow, Katy Hayward, Mark Shaefer & Cynthia McCoig. (2018) Effect of Sorbitol on the Pharmacokinetic Profile of Lamivudine Oral Solution in Adults: An Open-Label, Randomized Study. Clinical Pharmacology & Therapeutics 103:3, pages 402-408.
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Darren M. Moss, Paul Domanico, Melynda Watkins, Seonghee Park, Ryan Randolph, Steve Wring, Rajith Kumar Reddy Rajoli, James Hobson, Steve Rannard, Marco Siccardi & Andrew Owen. (2017) Simulating Intestinal Transporter and Enzyme Activity in a Physiologically Based Pharmacokinetic Model for Tenofovir Disoproxil Fumarate. Antimicrobial Agents and Chemotherapy 61:7.
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Esther J. H. Janssen, Diane E. T. Bastiaans, Pyry A. J. Välitalo, Annemarie M. C. van Rossum, Evelyne Jacqz-Aigrain, Hermione Lyall, Catherijne A. J. Knibbe & David M. Burger. (2017) Dose evaluation of lamivudine in human immunodeficiency virus-infected children aged 5 months to 18 years based on a population pharmacokinetic analysis. British Journal of Clinical Pharmacology 83:6, pages 1287-1297.
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Emily Huesgen, Kathryn E. DeSear, Eric F. Egelund, Renata Smith, Blake Max & Jennifer Janelle. (2016) A HAART-Breaking Review of Alternative Antiretroviral Administration: Practical Considerations with Crushing and Enteral Tube Scenarios. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 36:11, pages 1145-1165.
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Thomas N. Kakuda, Anne Brochot, Bruce Green, Steven Nijs, Peter Vis, Magda Opsomer, Frank L. Tomaka & Richard M. W. Hoetelmans. (2016) Pharmacokinetics and Pharmacokinetic/Pharmacodynamic Relationships of Etravirine in HIV-1-Infected, Treatment-Experienced Children and Adolescents in PIANO. The Journal of Clinical Pharmacology 56:11, pages 1395-1405.
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Alejandro Sosnik & Robin Augustine. (2016) Challenges in oral drug delivery of antiretrovirals and the innovative strategies to overcome them. Advanced Drug Delivery Reviews 103, pages 105-120.
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Adrienne F. Schlatter, Andrew R. Deathe & Rachel C. Vreeman. (2016) The Need for Pediatric Formulations to Treat Children with HIV. AIDS Research and Treatment 2016, pages 1-8.
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Sergio R. Ribone, Esteban M. Schenfeld, Marcela Madrid, Adriana B. Pierini & Mario A. Quevedo. (2016) Evaluation and synthesis of AZT prodrugs with optimized chemical stabilities: experimental and theoretical analyses. New J. Chem. 40:3, pages 2383-2392.
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