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Drug disposition alterations in liver disease: extrahepatic effects in cholestasis and nonalcoholic steatohepatitis

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Martyn Howard, Jill Barber, Naved Alizai & Amin Rostami-Hodjegan. (2018) Dose adjustment in orphan disease populations: the quest to fulfill the requirements of physiologically based pharmacokinetics. Expert Opinion on Drug Metabolism & Toxicology 14:12, pages 1315-1330.
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Pei-Li Zhu, Si-Yuan Pan, Shu-Feng Zhou, Yi Zhang, Xiao-Yan Wang, Nan Sun, Zhu-Sheng Chu, Zhi-Ling Yu & Kam-Ming Ko. (2015) Effects of combined dietary supplementation with fenofibrate and Schisandrae Fructus pulp on lipid and glucose levels and liver function in normal and hypercholesterolemic mice. Drug Design, Development and Therapy 9, pages 923-935.
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Yue Zu, Yanan Liu, Lulu Lan, Chen Zhu, Chengliang Zhang & Dong Liu. (2023) Consecutive baicalin treatment relieves its accumulation in rats with intrahepatic cholestasis by increasing MRP2 expression. Heliyon 9:1, pages e12689.
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Ronaldo Morales Junior, João Paulo Telles, Shaina Ying‐Ching Kwiatkowski, Vanessa D'Amaro Juodinis, Daniela Carla de Souza & Silvia Regina Cavani Jorge Santos. (2023) Pharmacokinetic and pharmacodynamic considerations of antibiotics and antifungals in liver transplantation recipients. Liver Transplantation 29:1, pages 91-102.
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Joseph L. Jilek, Kayla L. Frost, Solène Marie, Cassandra M. Myers, Michael Goedken, Stephen H. Wright & Nathan J. Cherrington. (2022) Attenuated Ochratoxin A Transporter Expression in a Mouse Model of Nonalcoholic Steatohepatitis Protects against Proximal Convoluted Tubule Toxicity. Drug Metabolism and Disposition 50:10, pages 1389-1395.
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Sonal Sharma, Jonathan G. Stine, Thomas Verbeek & Dmitri Bezinover. (2022) Management of Patients With Non-alcoholic Steatohepatitis Undergoing Liver Transplantation: Considerations for the Anesthesiologist. Journal of Cardiothoracic and Vascular Anesthesia 36:8, pages 2616-2627.
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Yu Wang, Haihong Hu, Jing Nie, Hui Zhou, Lushan Yu & Su Zeng. (2022) Inhibiting uptake activity of organic anion transporter 2 by bile acids. Drug Metabolism and Pharmacokinetics 43, pages 100448.
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O. Laatikainen, S. Sneck & M. Turpeinen. (2021) Medication-related adverse events in health care—what have we learned? A narrative overview of the current knowledge. European Journal of Clinical Pharmacology 78:2, pages 159-170.
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Catherine M. Pastor & Valérie Vilgrain. (2021) Steatosis Alters the Activity of Hepatocyte Membrane Transporters in Obese Rats. Cells 10:10, pages 2733.
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Tao Hu & Hongbing Wang. 2021. Transporters and Drug‐Metabolizing Enzymes in Drug Toxicity. Transporters and Drug‐Metabolizing Enzymes in Drug Toxicity 307 337 .
Ziwei Li, Yuanfeng Lyu, Jiajia Zhao, Dan Li, Zhixiu Lin, Kenneth Kin Wah To, Xiaoyu Yan & Zhong Zuo. (2021) Disease Status–Dependent Drug–Herb Interactions: NASH Lowered the Risk of Hepatotoxicity in Rats Coadministered With Simvastatin and Gardenia jasminoides J. Ellis. Frontiers in Pharmacology 12.
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Yvonne S. Lin, Kenneth E. Thummel, Brice D. Thompson, Rheem A. Totah & Christi W. Cho. 2021. Enzyme Kinetics in Drug Metabolism. Enzyme Kinetics in Drug Metabolism 481 550 .
Sheena Sharma, Deepak Suresh Ahire & Bhagwat Prasad. (2020) Utility of Quantitative Proteomics for Enhancing the Predictive Ability of Physiologically Based Pharmacokinetic Models Across Disease States. The Journal of Clinical Pharmacology 60:S1.
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Zi-Rui Huang, Min Chen, Wei-Ling Guo, Tian-Tian Li, Bin Liu, Wei-Dong Bai, Lian-Zhong Ai, Ping-Fan Rao, Li Ni & Xu-Cong Lv. (2020) Monascus purpureus-fermented common buckwheat protects against dyslipidemia and non-alcoholic fatty liver disease through the regulation of liver metabolome and intestinal microbiome. Food Research International 136, pages 109511.
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Zi-Rui Huang, Jia-Cong Deng, Qiu-Yi Li, Ying-Jia Cao, Yi-Chen Lin, Wei-Dong Bai, Bin Liu, Ping-Fan Rao, Li Ni & Xu-Cong Lv. (2020) Protective Mechanism of Common Buckwheat ( Fagopyrum esculentum Moench.) against Nonalcoholic Fatty Liver Disease Associated with Dyslipidemia in Mice Fed a High-Fat and High-Cholesterol Diet . Journal of Agricultural and Food Chemistry 68:24, pages 6530-6543.
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Varun Takyar, Anand Nath, Andrea Beri, Ahmed M. Gharib & Yaron Rotman. (2017) How healthy are the “Healthy volunteers”? Penetrance of NAFLD in the biomedical research volunteer pool. Hepatology 66:3, pages 825-833.
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Bhagwat Prasad, Marc Vrana, Aanchal Mehrotra, Katherine Johnson & Deepak Kumar Bhatt. (2017) The Promises of Quantitative Proteomics in Precision Medicine. Journal of Pharmaceutical Sciences 106:3, pages 738-744.
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Luisa Pozzo, Andrea Vornoli, Ilaria Coppola, Clara Maria Della Croce, Lucia Giorgetti, Pier Giovanni Gervasi & Vincenzo Longo. (2016) Effect of HFD/STZ on expression of genes involved in lipid, cholesterol and glucose metabolism in rats. Life Sciences 166, pages 149-156.
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Tomas Laho, John D. Clarke, Anika L. Dzierlenga, Hui Li, David M. Klein, Michael Goedken, Stanislav Micuda & Nathan J. Cherrington. (2016) Effect of nonalcoholic steatohepatitis on renal filtration and secretion of adefovir. Biochemical Pharmacology 115, pages 144-151.
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Amandla Atilano-Roque, Gavriel Roda, Uma Fogueri, Jennifer J. Kiser & Melanie S. Joy. (2016) Effect of Disease Pathologies on Transporter Expression and Function. The Journal of Clinical Pharmacology 56, pages S205-S221.
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Yaofeng Cheng, Chris Freeden, Yueping Zhang, Pamela Abraham, Hong Shen, Debra Wescott, W. Griffith Humphreys, Jinping Gan & Yurong Lai. (2016) Biliary excretion of pravastatin and taurocholate in rats with bile salt export pump (Bsep) impairment. Biopharmaceutics & Drug Disposition 37:5, pages 276-286.
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Hao Chen, Xiaotao Huang, Jianbin Min, Weirong Li, Rong Zhang, Wei Zhao, Changhui Liu, Lang Yi, Suiqing Mi, Ningsheng Wang, Qi Wang & Chenchen Zhu. (2016) Geniposidic acid protected against ANIT-induced hepatotoxity and acute intrahepatic cholestasis, due to Fxr-mediated regulation of Bsep and Mrp2. Journal of Ethnopharmacology 179, pages 197-207.
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