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Expert Opinion on Drug Metabolism & Toxicology Volume 10, 2014 - Issue 10
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ADMET considerations when prescribing novel therapeutics to treat restless legs syndrome

Stefano de BiaseUniversity of Udine Medical School, Department of Experimental and Clinical Medical Sciences, Neurology Unit, Udine, Italy;“S. Maria della Misericordia” University Hospital, Department of Neurosciences, Udine, Italy
, MD,
Giovanni Merlino“S. Maria della Misericordia” University Hospital, Department of Neurosciences, Udine, Italy
, MD PhD,
Simone LorenzutUniversity of Udine Medical School, Department of Experimental and Clinical Medical Sciences, Neurology Unit, Udine, Italy;“S. Maria della Misericordia” University Hospital, Department of Neurosciences, Udine, Italy
, MD,
Mariarosaria ValenteUniversity of Udine Medical School, Department of Experimental and Clinical Medical Sciences, Neurology Unit, Udine, Italy;“S. Maria della Misericordia” University Hospital, Department of Neurosciences, Udine, Italy
, MD &
Gian Luigi GigliUniversity of Udine Medical School, Department of Experimental and Clinical Medical Sciences, Neurology Unit, Udine, Italy;“S. Maria della Misericordia” University Hospital, Department of Neurosciences, Udine, Italy;University of Udine Medical School, Piazza Santa Maria della Misercordia, 15, 33100 Udine, Italy+39 0 432 989264; +39 0 432 989263; [email protected]
, MD (Professor, Director of Neurology)
Pages 1365-1380 | Published online: 22 Aug 2014

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Chukwunonso K. Nwabufo, Omozojie P. Aigbogun, Kevin J.H Allen, Madeline N. Owens, Jeremy S. Lee, Christopher P. Phenix & Ed S. Krol. (2021) Employing in vitro metabolism to guide design of F-labelled PET probes of novel α-synuclein binding bifunctional compounds. Xenobiotica 51:8, pages 885-900.
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Stefano de Biase, Gaia Pellitteri, Gian Luigi Gigli & Mariarosaria Valente. (2019) Advancing synthetic therapies for the treatment of restless legs syndrome. Expert Opinion on Pharmacotherapy 20:16, pages 1971-1980.
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Articles from other publishers (4)

Amanda Scanga, Anne-Louise Lafontaine & Marta Kaminska. (2023) An overview of the effects of levodopa and dopaminergic agonists on sleep disorders in Parkinson’s disease. Journal of Clinical Sleep Medicine 19:6, pages 1133-1144.
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Ting Wang, Leting Yang, Jing Hua, Huiru Xie, Xuehua Jiang & Ling Wang. (2016) Simultaneous bioanalysis of rasagiline and its major metabolites in human plasma by LC–MS/MS: Application to a clinical pharmacokinetic study. Journal of Pharmaceutical and Biomedical Analysis 125, pages 280-285.
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. (2016) Targinact for restless legs syndrome:. Drug and Therapeutics Bulletin 54:4, pages 42-45.
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Christina Kontoghiorghe, Annita Kolnagou & George Kontoghiorghes. (2015) Phytochelators Intended for Clinical Use in Iron Overload, Other Diseases of Iron Imbalance and Free Radical Pathology. Molecules 20:11, pages 20841-20872.
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