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Regulation of drug transporter expression and function in the placenta

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Jakub Hofman, Radim Kučera, Zuzana Neumanova, Jiri Klimes, Martina Ceckova & Frantisek Staud. (2016) Placental passage of olomoucine II, but not purvalanol A, is affected by p-glycoprotein (ABCB1), breast cancer resistance protein (ABCG2) and multidrug resistance-associated proteins (ABCCs). Xenobiotica 46:5, pages 416-423.
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Articles from other publishers (37)

Christine Gong, Lynn N. Bertagnolli, David W. Boulton & Paola Coppola. (2023) A Literature Review of Changes in Phase II Drug-Metabolizing Enzyme and Drug Transporter Expression during Pregnancy. Pharmaceutics 15:11, pages 2624.
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Péter Szatmári & Eszter Ducza. (2023) Changes in Expression and Function of Placental and Intestinal P-gp and BCRP Transporters during Pregnancy. International Journal of Molecular Sciences 24:17, pages 13089.
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Gautam Vijaywargi, Sivacharan Kollipara, Tausif Ahmed & Siddharth Chachad. (2022) Predicting transporter mediated drug–drug interactions via static and dynamic physiologically based pharmacokinetic modeling: A comprehensive insight on where we are now and the way forward. Biopharmaceutics & Drug Disposition 44:3, pages 195-220.
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Lukas Cerveny, Sara Karbanova, Rona Karahoda, Hana Horackova, Lucie Jiraskova, Mohammed Naji Husaen Ali & Frantisek Staud. (2023) Assessment of the role of nucleoside transporters, P-glycoprotein, breast cancer resistance protein, and multidrug resistance-associated protein 2 in the placental transport of entecavir using in vitro, ex vivo, and in situ methods. Toxicology and Applied Pharmacology 463, pages 116427.
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Jung-Hung Chen, I-Hsin Lin, Thomas Y. Hsueh, Jeffrey W. Dalley & Tung-Hu Tsai. (2022) Pharmacokinetics and transplacental transfer of codeine and codeine metabolites from Papaver somniferum L.. Journal of Ethnopharmacology 298, pages 115623.
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Michiko Yamashita & Udo R. Markert. (2021) Overview of Drug Transporters in Human Placenta. International Journal of Molecular Sciences 22:23, pages 13149.
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Chuan Wang, Dan Ma, Yimin Hua & Hongyu Duan. (2021) Modulation of Placental Breast Cancer Resistance Protein by HDAC1 in Mice: Implications for Optimization of Pharmacotherapy During Pregnancy. Reproductive Sciences 28:12, pages 3540-3546.
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Lukas Cerveny, Padma Murthi & Frantisek Staud. (2021) HIV in pregnancy: Mother-to-child transmission, pharmacotherapy, and toxicity. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1867:10, pages 166206.
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Xiaolei Wang, Pengyu Chen, Lixia Zhao, Lingyan Zhu & Fengchang Wu. (2021) Transplacental Behaviors of Organophosphate Tri- and Diesters Based on Paired Human Maternal and Cord Whole Blood: Efficiencies and Impact Factors. Environmental Science & Technology 55:5, pages 3091-3100.
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Antonio Ragusa, Alessandro Svelato, Criselda Santacroce, Piera Catalano, Valentina Notarstefano, Oliana Carnevali, Fabrizio Papa, Mauro Ciro Antonio Rongioletti, Federico Baiocco, Simonetta Draghi, Elisabetta D'Amore, Denise Rinaldo, Maria Matta & Elisabetta Giorgini. (2021) Plasticenta: First evidence of microplastics in human placenta. Environment International 146, pages 106274.
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Neelima Anup, Nimeet Desai, Kuldeep Rajpoot & Rakesh Kumar Tekade. 2021. Biopharmaceutics and Pharmacokinetics Considerations. Biopharmaceutics and Pharmacokinetics Considerations 145 162 .
Sascha C.T. Nicklisch & Amro Hamdoun. (2020) Disruption of small molecule transporter systems by Transporter‐Interfering Chemicals (TICs). FEBS Letters 594:23, pages 4158-4185.
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Lenka Tupova, Birgit Hirschmugl, Simona Sucha, Veronika Pilarova, Virág Székely, Éva Bakos, Lucie Novakova, Csilla Özvegy-Laczka, Christian Wadsack & Martina Ceckova. (2020) Interplay of drug transporters P-glycoprotein (MDR1), MRP1, OATP1A2 and OATP1B3 in passage of maraviroc across human placenta. Biomedicine & Pharmacotherapy 129, pages 110506.
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Xi Wang, Yanqin Song, Di Wu, Qian Li, Shanshan Lu, Xiaosu Li, Hua Huang & Jun Zhang. (2020) Inter-individual variations and modulators of MDR1 transport activity in human placenta. Placenta 97, pages 46-50.
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Joana Bicker, Gilberto Alves, Amílcar Falcão & Ana Fortuna. (2020) Timing in drug absorption and disposition: The past, present, and future of chronopharmacokinetics. British Journal of Pharmacology 177:10, pages 2215-2239.
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Maria Ellfolk, Aleksi Tornio, Mikko Niemi, Maarit K. Leinonen, Anna‐Maria Lahesmaa‐Korpinen & Heli Malm. (2020) Placental transporter‐mediated drug interactions and offspring congenital anomalies. British Journal of Clinical Pharmacology 86:5, pages 868-879.
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Irving Steinberg. 2019. Cardiac Problems in Pregnancy, 4th Edition. Cardiac Problems in Pregnancy, 4th Edition 433 455 .
Qingquan Zeng, Mengru Bai, Cui Li, Shuanghui Lu, Zhiyuan Ma, Yunchun Zhao, Hui Zhou, Huidi Jiang, Dongli Sun & Caihong Zheng. (2019) Multiple Drug Transporters Contribute to the Placental Transfer of Emtricitabine. Antimicrobial Agents and Chemotherapy 63:8.
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Arne Gessner, Jörg König & Martin F. Fromm. (2019) Clinical Aspects of Transporter‐Mediated Drug–Drug Interactions. Clinical Pharmacology & Therapeutics 105:6, pages 1386-1394.
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S. Karbanova, L. Cerveny, L. Jiraskova, R. Karahoda, M. Ceckova, Z. Ptackova & F. Staud. (2019) Transport of ribavirin across the rat and human placental barrier: Roles of nucleoside and ATP-binding cassette drug efflux transporters. Biochemical Pharmacology 163, pages 60-70.
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Najwa Najjar, Eliza R. McColl, Andrea Weckman, Kevin C. Kain & Micheline Piquette‐Miller. (2019) Dysregulation of solute carrier transporters in malaria‐infected pregnant mice. Parasite Immunology 41:4.
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Maria Botsivali & Soterios A. Kyrtopoulos. (2019) Transplacental exposure to carcinogens and risks to children: evidence from biomarker studies and the utility of omic profiling. Archives of Toxicology.
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Norman R. SaundersKatarzyna M. DziegielewskaKjeld Møllgård & Mark D. Habgood. (2019) Recent Developments in Understanding Barrier Mechanisms in the Developing Brain: Drugs and Drug Transporters in Pregnancy, Susceptibility or Protection in the Fetal Brain?. Annual Review of Pharmacology and Toxicology 59:1, pages 487-505.
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Frantisek Staud & Rona Karahoda. (2018) Trophoblast: The central unit of fetal growth, protection and programming. The International Journal of Biochemistry & Cell Biology 105, pages 35-40.
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Lukas Cerveny, Zuzana Ptackova, Martina Ceckova, Rona Karahoda, Sara Karbanova, Lucie Jiraskova, Susan L. Greenwood, Jocelyn D. Glazier & Frantisek Staud. (2018) Equilibrative Nucleoside Transporter 1 (ENT1, SLC29A1 ) Facilitates Transfer of the Antiretroviral Drug Abacavir across the Placenta . Drug Metabolism and Disposition 46:11, pages 1817-1826.
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Lukas Cerveny, Zuzana Ptackova, Marketa Durisova & Frantisek Staud. (2018) Interactions of protease inhibitors atazanavir and ritonavir with ABCB1, ABCG2, and ABCC2 transporters: Effect on transplacental disposition in rats. Reproductive Toxicology 79, pages 57-65.
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Lucie Jiraskova, Lukas Cerveny, Sara Karbanova, Zuzana Ptackova & Frantisek Staud. (2018) Expression of Concentrative Nucleoside Transporters ( SLC28A ) in the Human Placenta: Effects of Gestation Age and Prototype Differentiation-Affecting Agents . Molecular Pharmaceutics 15:7, pages 2732-2741.
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Harvey J Kliman, Sarah B Quaratella, Alessandra C Setaro, Erin C Siegman, Zarrin T Subha, Reshef Tal, Kristin M Milano & Theodore L Steck. (2018) Pathway of Maternal Serotonin to the Human Embryo and Fetus. Endocrinology 159:4, pages 1609-1629.
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S. Karbanova, L. Cerveny, M. Ceckova, Z. Ptackova, L. Jiraskova, S. Greenwood & F. Staud. (2017) Role of nucleoside transporters in transplacental pharmacokinetics of nucleoside reverse transcriptase inhibitors zidovudine and emtricitabine. Placenta 60, pages 86-92.
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Mengru Bai, Zhiyuan Ma, Dongli Sun, Caihong Zheng, Yayun Weng, Xi Yang, Ting Jiang & Huidi Jiang. (2017) Multiple drug transporters mediate the placental transport of sulpiride. Archives of Toxicology 91:12, pages 3873-3884.
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Hong-Yu Duan, Dan Ma, Kai-Yu Zhou, Tao Wang, Yi Zhang, Yi-Fei Li, Jin-Lin Wu, Yi-Min Hua & Chuan Wang. (2017) Effect of Histone Deacetylase Inhibition on the Expression of Multidrug Resistance-associated Protein 2 in a Human Placental Trophoblast Cell Line. Chinese Medical Journal 130:11, pages 1352-1360.
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Aizati N. A. Daud, Jorieke E. H. Bergman, Monika P. Oktora, Wilhelmina S. Kerstjens-Frederikse, Henk Groen, Jens H. Bos, Eelko Hak & Bob Wilffert. (2017) Maternal use of drug substrates of placental transporters and the effect of transporter-mediated drug interactions on the risk of congenital anomalies. PLOS ONE 12:3, pages e0173530.
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Karel Allegaert & John N. Van Den Anker. 2017. Fetal and Neonatal Physiology. Fetal and Neonatal Physiology 208 221.e4 .
Susanna Esposito, Rossana Tenconi, Valentina Preti, Elena Groppali & Nicola Principi. (2016) Chemotherapy against cancer during pregnancy. Medicine 95:38, pages e4899.
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Paul Brownbill, Igor Chernyavsky, Barbara Bottalico, Gernot Desoye, Stefan Hansson, Gerry Kenna, Lisbeth E. Knudsen, Udo R. Markert, Nicola Powles-Glover, Henning Schneider & Lopa Leach. (2016) An international network (PlaNet) to evaluate a human placental testing platform for chemicals safety testing in pregnancy. Reproductive Toxicology 64, pages 191-202.
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Stein Schalkwijk, Rick Greupink, Angela P. Colbers, Alfons C. Wouterse, Vivienne G. M. Verweij, Joris van Drongelen, Marga Teulen, Daphne van den Oetelaar, David M. Burger & Frans G. M. Russel. (2016) Placental transfer of the HIV integrase inhibitor dolutegravir in an ex vivo human cotyledon perfusion model . Journal of Antimicrobial Chemotherapy 71:2, pages 480-483.
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Emma M. Lofthouse, Suzanne Brooks, Jane K. Cleal, Mark A. Hanson, Kirsten R. Poore, Ita M. O'Kelly & Rohan M. Lewis. (2015) Glutamate cycling may drive organic anion transport on the basal membrane of human placental syncytiotrophoblast. The Journal of Physiology 593:20, pages 4549-4559.
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