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Maryam Mirahmad, Reyhaneh Sabourian, Mohammad Mahdavi, Bagher Larijani & Maliheh Safavi. (2022) In vitro cell-based models of drug-induced hepatotoxicity screening: progress and limitation. Drug Metabolism Reviews 54:2, pages 161-193.
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Richard J. Weaver, Catherine Betts, Eric A.G. Blomme, Helga H.J. Gerets, Klaus Gjervig Jensen, Philip G. Hewitt, Satu Juhila, Gilles Labbe, Michael J. Liguori, Natalie Mesens, Monday O. Ogese, Mikael Persson, Jan Snoeys, James L. Stevens, Tracy Walker & B. Kevin Park. (2017) Test systems in drug discovery for hazard identification and risk assessment of human drug-induced liver injury. Expert Opinion on Drug Metabolism & Toxicology 13:7, pages 767-782.
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Articles from other publishers (38)
Lu Yan, Catherine Jane Messner, Mingming Tian, Xiao Gou, Laura Suter-Dick & Xiaowei Zhang. (2022) Evaluation of dioxin induced transcriptomic responses in a 3D human liver microtissue model. Environmental Research 210, pages 112906.
Crossref
Crossref
Sitong Sun, Manshu Wang, Yu Yuan, Shuo Wang, Haoran Ding, Chenrui Liang, Xiaomeng Li, Simiao Fan & Yubo Li. (2022) A new strategy for the rapid identification and validation of direct toxicity targets of psoralen-induced hepatotoxicity. Toxicology Letters 363, pages 11-26.
Crossref
Crossref
Christopher Hadjittofi, Michael Feretis, Jack Martin, Simon Harper & Emmanuel Huguet. (2021) Liver regeneration biology: Implications for liver tumour therapies. World Journal of Clinical Oncology 12:12, pages 1101-1156.
Crossref
Crossref
Nicolas Fischer & Thomas Efferth. (2021) The impact of “omics” technologies for grapevine (Vitis vinifera) research. Journal of Berry Research 11:4, pages 567-581.
Crossref
Crossref
Yonela Ntamo, Khanyisani Ziqubu, Nireshni Chellan, Bongani B. Nkambule, Tawanda M. Nyambuya, Sithandiwe E. Mazibuko-Mbeje, Kwazikwakhe B. Gabuza, Fabio Marcheggiani, Luca Tiano & Phiwayinkosi V. Dludla. (2021) Drug-Induced Liver Injury: Clinical Evidence of N-Acetyl Cysteine Protective Effects. Oxidative Medicine and Cellular Longevity 2021, pages 1-12.
Crossref
Crossref
Nicolás Lundahl Ciano-Petersen, Pablo Cabezudo-García, Sergio Muñiz-Castrillo, Jérôme Honnorat, Pedro Jesús Serrano-Castro & Begoña Oliver-Martos. (2021) Current Status of Biomarkers in Anti-N-Methyl-D-Aspartate Receptor Encephalitis. International Journal of Molecular Sciences 22:23, pages 13127.
Crossref
Crossref
Daniel Desaulniers, Paule Vasseur, Abigail Jacobs, M. Cecilia Aguila, Norman Ertych & Miriam N. Jacobs. (2021) Integration of Epigenetic Mechanisms into Non-Genotoxic Carcinogenicity Hazard Assessment: Focus on DNA Methylation and Histone Modifications. International Journal of Molecular Sciences 22:20, pages 10969.
Crossref
Crossref
Humna Sajjad, Saiqa Imtiaz, Tayyaba Noor, Yusra Hasan Siddiqui, Anila Sajjad & Muhammad Zia. (2021) Cancer models in preclinical research: A chronicle review of advancement in effective cancer research. Animal Models and Experimental Medicine 4:2, pages 87-103.
Crossref
Crossref
Danqing Huang, Xiaoxuan Zhang, Xiao Fu, Yan Zu, Weijian Sun & Yuanjin Zhao. (2021) Liver spheroids on chips as emerging platforms for drug screening. Engineered Regeneration 2, pages 246-256.
Crossref
Crossref
Dilys Lam, Phuc-Loi Luu, Jenny Z. Song, Wenjia Qu, Gail P. Risbridger, Mitchell G. Lawrence, Jennifer Lu, Matt Trau, Darren Korbie, Susan J. Clark, Ruth Pidsley & Clare Stirzaker. (2020) Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels. Clinical Epigenetics 12:1.
Crossref
Crossref
Erin Milner, Michael Ainsworth, Matthew McDonough, Benjamin Stevens, Johannah Buehrer, Richard Delzell, Cameron Wilson & Jason Barnhill. (2020) Emerging Three-Dimensional Hepatic Models in Relation to Traditional Two-Dimensional In Vitro Assays for Evaluating Drug Metabolism and Hepatoxicity. Medicine in Drug Discovery 8, pages 100060.
Crossref
Crossref
Marie-Lynn Cuypers, Hugues Chanteux, Eric Gillent, Pierre Bonnaillie, Kenneth Saunders, Claire Beckers, Claude Delatour, Sylvie Dell’Aiera, Anna-Lena Ungell & Johan Nicolaï. (2020)
(–)-
N
-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-
N
-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
. Drug Metabolism and Disposition 48:11, pages 1121-1128.
Crossref
Crossref
Merrie Mosedale & Paul B. Watkins. (2020) Understanding Idiosyncratic Toxicity: Lessons Learned from Drug-Induced Liver Injury. Journal of Medicinal Chemistry 63:12, pages 6436-6461.
Crossref
Crossref
Sylvie Ricard-Blum & Adriana E. Miele. (2020) Omic approaches to decipher the molecular mechanisms of fibrosis, and design new anti-fibrotic strategies. Seminars in Cell & Developmental Biology 101, pages 161-169.
Crossref
Crossref
Rachid Jellali, Myriam Lereau Bernier, Yannick Tauran, Françoise Gilard, Mathieu Danoy, Taketomo Kido, Atsushi Miyajima, Yasuyuki Sakai & Eric Leclerc. (2020) Metabolomic profiling during the differentiation of human induced pluripotent stem cells into hepatocyte-like cells. Differentiation 112, pages 17-26.
Crossref
Crossref
Richard J. Weaver, Eric A. Blomme, Amy E. Chadwick, Ian M. Copple, Helga H. J. Gerets, Christopher E. Goldring, Andre Guillouzo, Philip G. Hewitt, Magnus Ingelman-Sundberg, Klaus Gjervig Jensen, Satu Juhila, Ursula Klingmüller, Gilles Labbe, Michael J. Liguori, Cerys A. Lovatt, Paul Morgan, Dean J. Naisbitt, Raymond H. H. Pieters, Jan Snoeys, Bob van de Water, Dominic P. Williams & B. Kevin Park. (2019) Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models. Nature Reviews Drug Discovery 19:2, pages 131-148.
Crossref
Crossref
Devin Hunt, Megan Branson, Victoria Gifford, Elizabeth Putnam & Mark Pershouse. 2020. Information Resources in Toxicology. Information Resources in Toxicology
453
469
.
Terezinha M. Souza, Jos C. S. Kleinjans & Danyel G. J. Jennen. 2019. Big Data in Predictive Toxicology. Big Data in Predictive Toxicology
214
241
.
Jian Jiang, Charlie D. Pieterman, Gökhan Ertaylan, Ralf L. M. Peeters & Theo M. C. M. de Kok. (2019) The application of omics-based human liver platforms for investigating the mechanism of drug-induced hepatotoxicity in vitro. Archives of Toxicology 93:11, pages 3067-3098.
Crossref
Crossref
Steven Hiemstra, Sreenivasa C. Ramaiahgari, Steven Wink, Giulia Callegaro, Maarten Coonen, John Meerman, Danyel Jennen, Karen van den Nieuwendijk, Anita Dankers, Jan Snoeys, Hans de Bont, Leo Price & Bob van de Water. (2019) High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability. Archives of Toxicology 93:10, pages 2895-2911.
Crossref
Crossref
J. Jiang, S. Messner, J.M. Kelm, M. van Herwijnen, D.G.J. Jennen, J.C. Kleinjans & T.M. de Kok. (2019) Human 3D multicellular microtissues: An upgraded model for the in vitro mechanistic investigation of inflammation-associated drug toxicity. Toxicology Letters 312, pages 34-44.
Crossref
Crossref
Claire G. Jeong, Gianni Dal Negro, Spiro Getsios & Jason E. Ekert. 2019. Microfluidic Cell Culture Systems. Microfluidic Cell Culture Systems
121
158
.
Antonio Rosato, Leonardo Tenori, Marta Cascante, Pedro Ramon De Atauri Carulla, Vitor A. P. Martins dos Santos & Edoardo Saccenti. (2018) From correlation to causation: analysis of metabolomics data using systems biology approaches. Metabolomics 14:4.
Crossref
Crossref
E.L. LeCluyse, L.M. Norona, J.A. Akingbasote, L.S. Howell, J.L. Woodhead, M.J. Cross, A.B. Roth & C.E. Goldring. 2018. Comprehensive Toxicology. Comprehensive Toxicology
651
712
.
Paul B. Watkins & Merrie Mosedale. 2017. Schiff's Diseases of the Liver. Schiff's Diseases of the Liver
774
798
.
Jarno E. J. Wolters, Simone G. J. van Breda, Florian Caiment, Sandra M. Claessen, Theo M. C. M. de Kok & Jos C. S. Kleinjans. (2017) Nuclear and Mitochondrial DNA Methylation Patterns Induced by Valproic Acid in Human Hepatocytes. Chemical Research in Toxicology 30:10, pages 1847-1854.
Crossref
Crossref
Barbara B. Raddatz, Ingo Spitzbarth, Katja A. Matheis, Arno Kalkuhl, Ulrich Deschl, Wolfgang Baumgärtner & Reiner Ulrich. (2017) Microarray-Based Gene Expression Analysis for Veterinary Pathologists: A Review. Veterinary Pathology 54:5, pages 734-755.
Crossref
Crossref
Zhao Peng, Liangkai Chen, Andreas K. Nüssler, Liegang Liu & Wei Yang. (2017) Current sights for mechanisms of deoxynivalenol-induced hepatotoxicity and prospective views for future scientific research: A mini review. Journal of Applied Toxicology 37:5, pages 518-529.
Crossref
Crossref
M Mosedale & PB Watkins. (2017) Drug-induced liver injury: Advances in mechanistic understanding that will inform risk management. Clinical Pharmacology & Therapeutics 101:4, pages 469-480.
Crossref
Crossref
Emanuel Raschi & Fabrizio De Ponti. (2017) Drug-induced liver injury: Towards early prediction and risk stratification. World Journal of Hepatology 9:1, pages 30.
Crossref
Crossref
Christoph Funk & Adrian Roth. (2016) Current limitations and future opportunities for prediction of DILI from in vitro. Archives of Toxicology 91:1, pages 131-142.
Crossref
Crossref
Chie Furihata, Takashi Watanabe, Takayoshi Suzuki, Shuichi Hamada & Madoka Nakajima. (2016) Collaborative studies in toxicogenomics in rodent liver in JEMS·MMS; a useful application of principal component analysis on toxicogenomics. Genes and Environment 38:1.
Crossref
Crossref
Suzanna HuppelschotenBob van de Water. (2016)
Drug-Induced Liver Injury and TNFα Signaling: From
In Vivo
Understanding to
In Vitro
Testing Approaches
. Applied In Vitro Toxicology 2:4, pages 197-206.
Crossref
Crossref
Katrin Zeilinger, Nora Freyer, Georg Damm, Daniel Seehofer & Fanny Knöspel. (2016)
Cell sources for
in vitro
human liver cell culture models
. Experimental Biology and Medicine 241:15, pages 1684-1698.
Crossref
Crossref
Ruani N. Fernando, Umesh Chaudhari, Sylvia E. Escher, Jan G. Hengstler, J?rgen Hescheler, Paul Jennings, Hector C. Keun, Jos C. S. Kleinjans, Raivo Kolde, Laxmikanth Kollipara, Annette Kopp-Schneider, Alice Limonciel, Harshal Nemade, Filomain Nguemo, Hedi Peterson, Pilar Prieto, Robim M. Rodrigues, Agapios Sachinidis, Christoph Sch?fer, Albert Sickmann, Dimitry Spitkovsky, Regina St?ber, Simone G. J. van Breda, Bob van de Water, Manon Vivier, Ren? P. Zahedi, Mathieu Vinken & Vera Rogiers. (2016) ?Watching the Detectives? report of the general assembly of the EU project DETECTIVE Brussels, 24?25 November 2015. Archives of Toxicology 90:6, pages 1529-1539.
Crossref
Crossref
M. José Gómez-Lechón, Laia Tolosa & M. Teresa Donato. (2016)
Metabolic activation and drug-induced liver injury:
in vitro
approaches for the safety risk assessment of new drugs
. Journal of Applied Toxicology 36:6, pages 752-768.
Crossref
Crossref
Franck A. Atienzar, Eric A. Blomme, Minjun Chen, Philip Hewitt, J. Gerry Kenna, Gilles Labbe, Frederic Moulin, Francois Pognan, Adrian B. Roth, Laura Suter-Dick, Okechukwu Ukairo, Richard J. Weaver, Yvonne Will & Donna M. Dambach. (2016) Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans. BioMed Research International 2016, pages 1-20.
Crossref
Crossref
Christine Lin & Salman R. Khetani. (2016) Advances in Engineered Liver Models for Investigating Drug-Induced Liver Injury. BioMed Research International 2016, pages 1-20.
Crossref
Crossref