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Insights on the human microbiome and its xenobiotic metabolism: what is known about its effects on human physiology?

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Ramy K. Aziz, Shaimaa M. Hegazy, Reem Yasser, Mariam R. Rizkallah & Marwa T. ElRakaiby. (2018) Drug pharmacomicrobiomics and toxicomicrobiomics: from scattered reports to systematic studies of drug–microbiome interactions. Expert Opinion on Drug Metabolism & Toxicology 14:10, pages 1043-1055.
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Houkai Li, Jiaojiao He & Wei Jia. (2016) The influence of gut microbiota on drug metabolism and toxicity. Expert Opinion on Drug Metabolism & Toxicology 12:1, pages 31-40.
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Almut Heinken, Johannes Hertel, Geeta Acharya, Dmitry A. Ravcheev, Malgorzata Nyga, Onyedika Emmanuel Okpala, Marcus Hogan, Stefanía Magnúsdóttir, Filippo Martinelli, Bram Nap, German Preciat, Janaka N. Edirisinghe, Christopher S. Henry, Ronan M. T. Fleming & Ines Thiele. (2023) Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine. Nature Biotechnology.
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Hui-Qing Chen, Jin-Yu Gong, Kai Xing, Mou-Ze Liu, Huan Ren & Jian-Quan Luo. (2022) Pharmacomicrobiomics: Exploiting the Drug-Microbiota Interactions in Antihypertensive Treatment. Frontiers in Medicine 8.
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Akhileshwar Kumar Srivastava, Dhruv Kumar, Divya Singh & Rajesh Kumar Singh. 2022. Xenobiotics in Chemical Carcinogenesis. Xenobiotics in Chemical Carcinogenesis 217 243 .
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Almut Heinken, Arianna Basile, Johannes Hertel, Cyrille Thinnes & Ines Thiele. (2021) Genome-Scale Metabolic Modeling of the Human Microbiome in the Era of Personalized Medicine. Annual Review of Microbiology 75:1, pages 199-222.
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Fiona Pham, Fabien Moinard-Butot, Clélia Coutzac & Nathalie Chaput. (2021) Cancer and immunotherapy: a role for microbiota composition. European Journal of Cancer 155, pages 145-154.
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Paulina Średnicka, Edyta Juszczuk-Kubiak, Michał Wójcicki, Monika Akimowicz & Marek Ł. Roszko. (2021) Probiotics as a biological detoxification tool of food chemical contamination: A review. Food and Chemical Toxicology 153, pages 112306.
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Lorenza Lucidi, Mauro Pettorruso, Federica Vellante, Francesco Di Carlo, Franca Ceci, Maria Chiara Santovito, Ilenia Di Muzio, Michele Fornaro, Antonio Ventriglio, Carmine Tomasetti, Alessandro Valchera, Alessandro Gentile, Yong-Ku Kim, Giovanni Martinotti, Silvia Fraticelli, Massimo Di Giannantonio & Domenico De Berardis. (2021) Gut Microbiota and Bipolar Disorder: An Overview on a Novel Biomarker for Diagnosis and Treatment. International Journal of Molecular Sciences 22:7, pages 3723.
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Lisa Lemoine, Ralf Dieckmann, Sascha Al Dahouk, Szilvia Vincze, Andreas Luch & Tewes Tralau. (2020) Microbially competent 3D skin: a test system that reveals insight into host–microbe interactions and their potential toxicological impact. Archives of Toxicology 94:10, pages 3487-3502.
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Radislav Nakov & Tsvetelina Velikova. (2020) Chemical Metabolism of Xenobiotics by Gut Microbiota. Current Drug Metabolism 21:4, pages 260-269.
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Jolantha Beyerle, Andreana N. Holowatyj, Mariam Haffa, Eva Frei, Biljana Gigic, Petra Schrotz-King, Juergen Boehm, Nina Habermann, Marie Stiborova, Dominique Scherer, Torsten Kölsch, Stephanie Skender, Nikolaus Becker, Esther Herpel, Martin Schneider, Alexis Ulrich, Peter Schirmacher, Jenny Chang-Claude, Hermann Brenner, Michael Hoffmeister, Ulrike Haug, Robert W. Owen & Cornelia M. Ulrich. (2020) Expression Patterns of Xenobiotic-Metabolizing Enzymes in Tumor and Adjacent Normal Mucosa Tissues among Patients with Colorectal Cancer: The ColoCare Study. Cancer Epidemiology, Biomarkers & Prevention 29:2, pages 460-469.
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Jason M. Koontz, Blair C. R. Dancy, Cassandra L. Horton, Jonathan D. Stallings, Valerie T. DiVito & John A. Lewis. (2019) The Role of the Human Microbiome in Chemical Toxicity. International Journal of Toxicology 38:4, pages 251-264.
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Gerard Clarke, Kiran V. Sandhu, Brendan T. Griffin, Timothy G. Dinan, John F. Cryan & Niall P. Hyland. (2019) Gut Reactions: Breaking Down Xenobiotic–Microbiome Interactions. Pharmacological Reviews 71:2, pages 198-224.
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Viktoriia Burkina, Martin Krøyer Rasmussen, Yelyzaveta Oliinychenko & Galia Zamaratskaia. (2019) Porcine cytochrome 2A19 and 2E1. Basic & Clinical Pharmacology & Toxicology 124:1, pages 32-39.
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Andrew Whang, Ravinder Nagpal & Hariom Yadav. (2019) Bi-directional drug-microbiome interactions of anti-diabetics. EBioMedicine 39, pages 591-602.
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Jing Zhan, Yiran Liang, Donghui Liu, Xiaoran Ma, Peize Li, Chang Liu, Xueke Liu, Peng Wang & Zhiqiang Zhou. (2018) Antibiotics may increase triazine herbicide exposure risk via disturbing gut microbiota. Microbiome 6:1.
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Walter R Terra, Renata O Dias, Pedro L Oliveira, Clélia Ferreira & Thiago M Venancio. (2018) Transcriptomic analyses uncover emerging roles of mucins, lysosome/secretory addressing and detoxification pathways in insect midguts. Current Opinion in Insect Science 29, pages 34-40.
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F. Oesch, E. Fabian & Robert Landsiedel. (2018) Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models. Archives of Toxicology 92:8, pages 2411-2456.
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Christian Riebeling, Andreas Luch & Tewes Tralau. (2018) Skin toxicology and 3Rs-Current challenges for public health protection. Experimental Dermatology 27:5, pages 526-536.
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Min Sun Choi, Jun Sang Yu, Hye Hyun Yoo & Dong-Hyun Kim. (2018) The role of gut microbiota in the pharmacokinetics of antihypertensive drugs. Pharmacological Research 130, pages 164-171.
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Nicholas A. Stella, Kimberly M. Brothers, Jake D. Callaghan, Angelina M. Passerini, Cihad Sigindere, Preston J. Hill, Xinyu Liu, Daniel J. Wozniak & Robert M. Q. Shanks. (2018) An IgaA/UmoB Family Protein from Serratia marcescens Regulates Motility, Capsular Polysaccharide Biosynthesis, and Secondary Metabolite Production. Applied and Environmental Microbiology 84:6.
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Jeon-Kyung Kim, Min Sun Choi, Jin-Ju Jeong, Su-Min Lim, In Sook Kim, Hye Hyun Yoo & Dong-Hyun Kim. (2018) Effect of Probiotics on Pharmacokinetics of Orally Administered Acetaminophen in Mice. Drug Metabolism and Disposition 46:2, pages 122-130.
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Adiel C. Rios, Pawan Kumar Maurya, Mariana Pedrini, Maiara Zeni-Graiff, Elson Asevedo, Rodrigo B. Mansur, Andrea Wieck, Rodrigo Grassi-Oliveira, Roger S. McIntyre, Mirian A.F. Hayashi & Elisa Brietzke. (2017) Microbiota abnormalities and the therapeutic potential of probiotics in the treatment of mood disorders. Reviews in the Neurosciences 28:7, pages 739-749.
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Stavros Bashiardes, Timur Tuganbaev, Sara Federici & Eran Elinav. (2017) The microbiome in anti-cancer therapy. Seminars in Immunology 32, pages 74-81.
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Ines Thiele, Catherine M. Clancy, Almut Heinken & Ronan M.T. Fleming. (2017) Quantitative systems pharmacology and the personalized drug–microbiota–diet axis. Current Opinion in Systems Biology 4, pages 43-52.
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Tewes Tralau & Andreas Luch. (2017) The human microbiome, from Achilles armour to Nessus’ shirt. Archives of Toxicology 91:7, pages 2699-2701.
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Juliane Sowada, Lisa Lemoine, Karsten Schön, Christoph Hutzler, Andreas Luch & Tewes Tralau. (2017) Toxification of polycyclic aromatic hydrocarbons by commensal bacteria from human skin. Archives of Toxicology 91:6, pages 2331-2341.
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Jean-Marie Nicolas, François Bouzom, Chanteux Hugues & Anna-Lena Ungell. (2017) Oral drug absorption in pediatrics: the intestinal wall, its developmental changes and current tools for predictions. Biopharmaceutics & Drug Disposition 38:3, pages 209-230.
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Nancy J. Ames, Alexandra Ranucci, Brad Moriyama & Gwenyth R. Wallen. (2017) The Human Microbiome and Understanding the 16S rRNA Gene in Translational Nursing Science. Nursing Research 66:2, pages 184-197.
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Rodney R. Dietert. (2017) The microbiome-immune-host defense barrier complex (microimmunosome) and developmental programming of noncommunicable diseases. Reproductive Toxicology 68, pages 49-58.
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Peter Spanogiannopoulos, Elizabeth N. Bess, Rachel N. Carmody & Peter J. Turnbaugh. (2016) The microbial pharmacists within us: a metagenomic view of xenobiotic metabolism. Nature Reviews Microbiology 14:5, pages 273-287.
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John William Honour. (2015) Historical perspective: gut dysbiosis and hypertension. Physiological Genomics 47:10, pages 443-446.
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Dong-Hyun Kim. (2015) Gut Microbiota-Mediated Drug-Antibiotic Interactions. Drug Metabolism and Disposition 43:10, pages 1581-1589.
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