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Review

Stereoselectivity in drug metabolism

Pages 149-158 | Published online: 11 Apr 2007

Keep up to date with the latest research on this topic with citation updates for this article.

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Dong-Hyun Kim. (2023) Interaction of drugs with gut microbiota modulators. Drug Metabolism Reviews 55:3, pages 181-194.
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Leyla Karadurmus, Mehmet Gumustas, Nurgul K. Bakirhan & Sibel A. Ozkan. (2023) Chiral Sensing as a Future Challenge in Electroanalytical Chemistry: Cyclodextrin-Based Chiral Sensors. Critical Reviews in Analytical Chemistry 53:3, pages 498-519.
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Jing Gu, Zheng Sui, Chunshu Fang & Qunyou Tan. (2017) Stereochemical considerations in pharmacokinetic processes of representative antineoplastic agents. Drug Metabolism Reviews 49:4, pages 438-450.
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Christian Höcht, Facundo Martín Bertera, Julieta Sofía Del Mauro & Carlos Alberto Taira. (2014) Models for evaluating the pharmacokinetics and pharmacodynamics for β-blockers. Expert Opinion on Drug Metabolism & Toxicology 10:4, pages 525-541.
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Ping Zhang, Zhigang Shen, Xinyuan Xu, Wentao Zhu, Ziheng Dang, Xinru Wang, Donghui Liu & Zhiqiang Zhou. (2012) Stereoselective degradation of metalaxyl and its enantiomers in rat and rabbit hepatic microsomes in vitro. Xenobiotica 42:6, pages 580-586.
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Y. L. Song, W. H. Jing, H. Y. Zhao, R. Yan, P. T. Li & Y. T. Wang. (2012) Stereoselective metabolism of (±)-praeruptorin A, a calcium channel blocker from Peucedani Radix, in pooled liver microsomes of rats and humans. Xenobiotica 42:3, pages 231-237.
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Eva Choong, Maria Dobrinas, Pierre-Alain Carrupt & Chin B Eap. (2010) The permeability P-glycoprotein: a focus on enantioselectivity and brain distribution. Expert Opinion on Drug Metabolism & Toxicology 6:8, pages 953-965.
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Christian Höcht, Facundo Martín Bertera, Marcos Alejandro Mayer & Carlos Alberto Taira. (2010) Issues in drug metabolism of major antihypertensive drugs: β-blockers, calcium channel antagonists and angiotensin receptor blockers. Expert Opinion on Drug Metabolism & Toxicology 6:2, pages 199-211.
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W. Zhu, Z. Dang, J. Qiu, Y. Liu, C. Lv, J. Diao & Z. Zhou. (2009) Species differences for stereoselective metabolism of ethofumesate and its enantiomers in vitro. Xenobiotica 39:9, pages 649-655.
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Imran Ali, Kishwar Saleem, Iqbal Hussain, VinayD. Gaitonde & HassanY. Aboul‐Enein. (2009) Polysaccharides Chiral Stationary Phases in Liquid Chromatography. Separation & Purification Reviews 38:2, pages 97-147.
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H. H. Yoo, N. S. Kim, J. Lee, D. R. Sohn, C. Jin & D. H. Kim. (2009) Characterization of human cytochrome P450 enzymes involved in the biotransformation of eperisone. Xenobiotica 39:1, pages 1-10.
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