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Review

Physiologically based approaches towards the prediction of pharmacokinetics: in vitro–in vivo extrapolation

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Pages 865-878 | Published online: 21 Nov 2007

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Miyoung Yoon, Jerry L. Campbell, Melvin E. Andersen & Harvey J. Clewell. (2012) Quantitative in vitro to in vivo extrapolation of cell-based toxicity assay results. Critical Reviews in Toxicology 42:8, pages 633-652.
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M. Moiz Mumtaz, Meredith Ray, Susan R. Crowell, Deborah Keys, Jeffrey Fisher & Patricia Ruiz. (2012) Translational Research to Develop a Human PBPK Models Tool Kit—Volatile Organic Compounds (VOCs). Journal of Toxicology and Environmental Health, Part A 75:1, pages 6-24.
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Jennifer B Dressman, Kirstin Thelen & Stefan Willmann. (2011) An update on computational oral absorption simulation. Expert Opinion on Drug Metabolism & Toxicology 7:11, pages 1345-1364.
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Karen Rowland Yeo, Mohsen Aarabi, Masoud Jamei & Amin Rostami-Hodjegan. (2011) Modeling and predicting drug pharmacokinetics in patients with renal impairment. Expert Review of Clinical Pharmacology 4:2, pages 261-274.
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Melvin E. Andersen, Mustafa Al-Zoughool, Maxine Croteau, Margit Westphal & Daniel Krewski. (2010) The Future of Toxicity Testing. Journal of Toxicology and Environmental Health, Part B 13:2-4, pages 163-196.
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Pascal Espié, Dominique Tytgat, Maria-Laura Sargentini-Maier, Italo Poggesi & Jean-Baptiste Watelet. (2009) Physiologically based pharmacokinetics (PBPK). Drug Metabolism Reviews 41:3, pages 391-407.
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James M. Gallo. (2010) Pharmacokinetic/ Pharmacodynamic‐Driven Drug Development. Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine 77:4, pages 381-388.
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Aki T. Heikkinen, Timo Korjamo, Varpu Lepikkö & Jukka Mönkkönen. (2010) Effects of Experimental Setup on the Apparent Concentration Dependency of Active Efflux Transport in in Vitro Cell Permeation Experiments . Molecular Pharmaceutics 7:2, pages 605-617.
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Deepak Dalvie, Ping Kang, Michael Zientek, Cathie Xiang, Sue Zhou & R. Scott Obach. (2008) Effect of Intestinal Glucuronidation in Limiting Hepatic Exposure and Bioactivation of Raloxifene in Humans and Rats. Chemical Research in Toxicology 21:12, pages 2260-2271.
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Michael B. Bolger, Robert Fraczkiewicz & Viera Lukacova. 2008. Drug Bioavailability. Drug Bioavailability 453 495 .
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