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Mackenzie Hadi, Yixi Chen, Viktoriia Starokozhko, Marjolijn T. Merema & Geny M.M. Groothuis. (2012) Mouse Precision-Cut Liver Slices as an ex Vivo Model To Study Idiosyncratic Drug-Induced Liver Injury. Chemical Research in Toxicology 25:9, pages 1938-1947.
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Thomas Efferth & Henry Johannes Greten. 2012. Recent Trends in Medicinal Plants Research. Recent Trends in Medicinal Plants Research
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Paul M. van Midwoud, Marjolijn T. Merema, Elisabeth Verpoorte & Geny M.M. Groothuis. (2011) Microfluidics Enables Small-Scale Tissue-Based Drug Metabolism Studies with Scarce Human Tissue. JALA: Journal of the Association for Laboratory Automation 16:6, pages 468-476.
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Hans-Udo Kasper, Elisabeth Konze, Nikolina Kutinová Canová, Hans Peter Dienes & Volker Dries. (2011) Cryopreservation of precision cut tissue slices (PCTS): Investigation of morphology and reactivity. Experimental and Toxicologic Pathology 63:6, pages 575-580.
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Paul M. van Midwoud, Marjolijn T. Merema, Niek Verweij, Geny M.M. Groothuis & Elisabeth Verpoorte. (2011) Hydrogel embedding of precision-cut liver slices in a microfluidic device improves drug metabolic activity. Biotechnology and Bioengineering 108:6, pages 1404-1412.
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M.G.L. Elferink, P. Olinga, E.M. van Leeuwen, S. Bauerschmidt, J. Polman, W.G. Schoonen, S.H. Heisterkamp & G.M.M. Groothuis. (2011) Gene expression analysis of precision-cut human liver slices indicates stable expression of ADME-Tox related genes. Toxicology and Applied Pharmacology 253:1, pages 57-69.
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Ansar A. Khan, Edwin C.Y. Chow, Robert J. Porte, K. Sandy Pang & Geny M.M. Groothuis. (2011) The role of lithocholic acid in the regulation of bile acid detoxication, synthesis, and transport proteins in rat and human intestine and liver slices. Toxicology in Vitro 25:1, pages 80-90.
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Paul M. van Midwoud, Elisabeth Verpoorte & Geny M. M. Groothuis. (2011) Microfluidic devices for in vitro studies on liver drug metabolism and toxicity. Integrative Biology 3:5, pages 509.
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Paul M. van Midwoud, Joost Janssen, Marjolijn T. Merema, Inge A. M. de Graaf, Geny M. M. Groothuis & Elisabeth Verpoorte. (2010) On-line HPLC Analysis System for Metabolism and Inhibition Studies in Precision-Cut Liver Slices. Analytical Chemistry 83:1, pages 84-91.
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Gabriel Baverel, Sophie Renault, Hassan Faiz, Maha El Hage, Catherine Gauthier, Agnès Duplany, Bernard Ferrier & Guy Martin. 2011. Drug Safety Evaluation. Drug Safety Evaluation
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Inge A M de Graaf, Peter Olinga, Marina H de Jager, Marjolijn T Merema, Ruben de Kanter, Esther G van de Kerkhof & Geny M M Groothuis. (2010) Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies. Nature Protocols 5:9, pages 1540-1551.
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Ansar A. Khan, Bieuwke S. Dragt, Robert J. Porte & Geny M.M. Groothuis. (2010) Regulation of VDR expression in rat and human intestine and liver – Consequences for CYP3A expression. Toxicology in Vitro 24:3, pages 822-829.
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Paul M. van Midwoud, Marjolijn T. Merema, Elisabeth Verpoorte & Geny M. M. Groothuis. (2010) A microfluidic approach for in vitro assessment of interorgan interactions in drug metabolism using intestinal and liver slices. Lab on a Chip 10:20, pages 2778.
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Sigridur A. Ásgeirsdóttir, Eduard G. Talman, Inge A. de Graaf, Jan A.A.M. Kamps, Simon C. Satchell, Peter W. Mathieson, Marcel H.J. Ruiters & Grietje Molema. (2010) Targeted transfection increases siRNA uptake and gene silencing of primary endothelial cells in vitro — A quantitative study. Journal of Controlled Release 141:2, pages 241-251.
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Christiane Guguen-Guillouzo & Andre Guillouzo. 2010. Hepatocytes. Hepatocytes
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Matijs van Meurs, Neng F. Kurniati, Francis M. Wulfert, Sigridur A. Asgeirsdottir, Inge A. de Graaf, Simon C. Satchell, Peter W. Mathieson, Rianne M. Jongman, Philipp Kümpers, Jan G. Zijlstra, Peter Heeringa & Grietje Molema. (2009) Shock-induced stress induces loss of microvascular endothelial Tie2 in the kidney which is not associated with reduced glomerular barrier function. American Journal of Physiology-Renal Physiology 297:2, pages F272-F281.
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Ansar A. Khan, Edwin C.Y. Chow, Anne-miek M.A. van Loenen-Weemaes, Robert J. Porte, K. Sandy Pang & Geny M.M. Groothuis. (2009) Comparison of effects of VDR versus PXR, FXR and GR ligands on the regulation of CYP3A isozymes in rat and human intestine and liver. European Journal of Pharmaceutical Sciences 37:2, pages 115-125.
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Amelie Lupp, Reinhild Glöckner, Joachim Etzrodt & Dieter Müller. (2008) Precision-cut liver slices from rats of different ages: basal cytochrome P450-dependent monooxygenase activities and inducibility. Analytical and Bioanalytical Chemistry 392:6, pages 1173-1184.
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R. Glöckner, A. Lieder & A. Lupp. (2008) Determination of CYP activity in precision-cut liver slices: whether to use intact slices or slice homogenate. Analytical and Bioanalytical Chemistry 392:6, pages 1167-1172.
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P. Olinga, M.G.L. Elferink, A.L. Draaisma, M.T. Merema, J.V. Castell, G. Pérez & G.M.M. Groothuis. (2008) Coordinated induction of drug transporters and phase I and II metabolism in human liver slices. European Journal of Pharmaceutical Sciences 33:4-5, pages 380-389.
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