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James J Cali, Dongping Ma, Monika G Wood, Poncho L Meisenheimer & Dieter H Klaubert. (2012) Bioluminescent assays for ADME evaluation: dialing in CYP selectivity with luminogenic substrates. Expert Opinion on Drug Metabolism & Toxicology 8:9, pages 1115-1130.
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Wilson Z Shou & Jun Zhang. (2010) Recent development in high-throughput bioanalytical support for in vitro ADMET profiling. Expert Opinion on Drug Metabolism & Toxicology 6:3, pages 321-336.
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Andrew L Niles, Richard A Moravec & Terry L Riss. (2008) Update on in vitro cytotoxicity assays for drug development. Expert Opinion on Drug Discovery 3:6, pages 655-669.
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Articles from other publishers (39)
Stefano Fontana, Simone Braggio, Mauro Corsi, Rob Riley, Chris Strock, Jenifer Bradley, Caterina Virginio & Paul Walker. 2023. The Handbook of Medicinal Chemistry. The Handbook of Medicinal Chemistry
533
596
.
Kasem KulkeawKasem Kulkeaw. 2023. Emergence of In Vitro 3D Systems to Model Human Malaria. Emergence of In Vitro 3D Systems to Model Human Malaria
45
66
.
Maite V. Aguinaga Martínez, Natali Jozičová, Jan Dušek, Burkhard Horstkotte, Petr Pávek, Manuel Miró & Hana Sklenářová. (2022) Real-time monitoring of Metridia luciferase release from cells upon interaction with model toxic substances by a fully automatic flow setup – A proof of concept. Talanta 245, pages 123465.
Crossref
Crossref
Hannah M. Work, Sylvie E. Kandel & Jed N. Lampe. (2021) Characterization of fluorescent probe substrates to develop an efficient high-throughput assay for neonatal hepatic CYP3A7 inhibition screening. Scientific Reports 11:1.
Crossref
Crossref
Marija Pinne & Judy L. Raucy. 2021. Cytochrome P450. Cytochrome P450
141
155
.
Sara Eyal. 2020. Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy. Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy
97
120
.
Maria Maddalena Calabretta, Laura Montali, Antonia Lopreside, Elisa Michelini & Aldo Roda. 2020. Bioluminescent Imaging. Bioluminescent Imaging
3
14
.
Sandra Ortega Ugalde, Dongping Ma, James J. Cali & Jan N.M. Commandeur. (2019) Evaluation of Luminogenic Substrates as Probe Substrates for Bacterial Cytochrome P450 Enzymes: Application to Mycobacterium tuberculosis. SLAS Discovery 24:7, pages 745-754.
Crossref
Crossref
Beatriz BaragañaBarbara ForteRyan ChoiStephen Nakazawa HewittJuan A. Bueren-CalabuigJoão Pedro Pisco, Caroline PeetDavid M. DranowDavid A. RobinsonChimed JansenNeil R. NorcrossSumiti VinayakMark AndersonCarrie F. BrooksCaitlin A. CooperSebastian DamerowMichael DelvesKaren DowersJames DuffyThomas E. EdwardsIrene HallyburtonBenjamin G. HorstMatthew A. HulversonLiam FergusonMaría Belén Jiménez-DíazRajiv S. JumaniDonald D. LorimerMelissa S. LoveSteven MaherHolly MatthewsCase W. McNamaraPeter MillerSandra O’NeillKayode K. Ojo, Maria Osuna-CabelloErika PintoJohn PostJennifer RileyMatthias RottmannLaura M. SanzPaul ScullionArvind Sharma, Sharon M. ShepherdYoko ShishikuraFrederick R. C. SimeonsErin E. StebbinsLaste StojanovskiUrsula StraschilFabio K. TamakiJevgenia TamjarLeah S. TorrieAmélie VantauxBenoît WitkowskiSergio WittlinManickam YogavelFabio ZuccottoIñigo Angulo-BarturenRobert SindenJake Baum, Francisco-Javier GamoPascal MäserDennis E. KyleElizabeth A. WinzelerPeter J. MylerPaul G. WyattDavid FloydDavid MatthewsAmit SharmaBoris StriepenChristopher D. HustonDavid W. GrayAlan H. Fairlamb, Andrei V. PisliakovChris Walpole, Kevin D. ReadWesley C. Van VoorhisIan H. Gilbert. (2019) Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. Proceedings of the National Academy of Sciences 116:14, pages 7015-7020.
Crossref
Crossref
Hong Shen, Zhifeng Yao, Weipeng Zhao, Yaping Zhang, Chenling Yao & Chaoyang Tong. (2018) miR‑21 enhances the protective effect of loperamide on rat cardiomyocytes against hypoxia/reoxygenation, reactive oxygen species production and apoptosis via regulating Akap8 and Bard1 expression. Experimental and Therapeutic Medicine.
Crossref
Crossref
Jonas Philipp Becker, Jannick Robert Clemens, Dirk Theile & Johanna Weiss. (2016) Bortezomib and ixazomib protect firefly luciferase from degradation and can flaw respective reporter gene assays. Analytical Biochemistry 509, pages 124-129.
Crossref
Crossref
Zinaida M. Kaskova, Aleksandra S. Tsarkova & Ilia V. Yampolsky. (2016) 1001 lights: luciferins, luciferases, their mechanisms of action and applications in chemical analysis, biology and medicine. Chemical Society Reviews 45:21, pages 6048-6077.
Crossref
Crossref
Saulius Šatkauskas, Baltramiejus Jakštys, Paulius Ruzgys & Milda Jakutavičiūtė. 2016. Handbook of Electroporation. Handbook of Electroporation
1
14
.
Young-Hoon Kim, Young-Ji Bae, Hyung Soo Kim, Hey-Jin Cha, Jae-Suk Yun, Ji-Soon Shin, Won-Keun Seong, Yong-Moon Lee & Kyoung-Moon Han. (2015) Measurement of Human Cytochrome P450 Enzyme Induction Based on Mesalazine and Mosapride Citrate Treatments Using a Luminescent Assay. Biomolecules & Therapeutics 23:5, pages 486-492.
Crossref
Crossref
Aniv Mann, Inessa Semenenko, Michal Meir & Sara Eyal. (2015) Molecular Imaging of Membrane Transporters’ Activity in Cancer: a Picture is Worth a Thousand Tubes. The AAPS Journal 17:4, pages 788-801.
Crossref
Crossref
Ramesh Ramji, Cheong Fook Cheong, Hiroaki Hirata, Abdur Rub Abdur Rahman & Chwee Teck Lim. (2015) Rapid Quantification of Live Cell Receptors Using Bioluminescence in a Flow-Based Microfluidic Device. Small 11:8, pages 943-951.
Crossref
Crossref
L. Cevenini, M. M. Calabretta, D. Calabria, A. Roda & E. Michelini. 2016. Bioluminescence: Fundamentals and Applications in Biotechnology - Volume 3. Bioluminescence: Fundamentals and Applications in Biotechnology - Volume 3
3
17
.
Hironori Sakai & Naohisa Wada. (2014) Full-quantum chemical calculations of the absorption maxima of oxyluciferin in the catalytic center of firefly luciferase containing adenosine monophosphate. Computational and Theoretical Chemistry 1045, pages 93-98.
Crossref
Crossref
Zachary F. Walls, Sheeba Varghese Gupta, Gordon L. Amidon & Kyung-Dall Lee. (2014) Synthesis and characterization of valyloxy methoxy luciferin for the detection of valacyclovirase and peptide transporter. Bioorganic & Medicinal Chemistry Letters 24:20, pages 4781-4783.
Crossref
Crossref
Elisa Michelini, Luca Cevenini, Maria Maddalena Calabretta, Donato Calabria & Aldo Roda. (2014) Exploiting in vitro and in vivo bioluminescence for the implementation of the three Rs principle (replacement, reduction, and refinement) in drug discovery. Analytical and Bioanalytical Chemistry 406:23, pages 5531-5539.
Crossref
Crossref
Dao-Lu Liu, Ying-Jie Li, Nan Yao, Jun Xu, Zhe-Sheng Chen, Anita Yiu, Cui-Xian Zhang, Wen-Cai Ye & Dong-Mei Zhang. (2014) Acerinol, a cyclolanstane triterpenoid from Cimicifuga acerina, reverses ABCB1-mediated multidrug resistance in HepG2/ADM and MCF-7/ADR cells. European Journal of Pharmacology 733, pages 34-44.
Crossref
Crossref
Myron K. Evans, Artak Tovmasyan, Ines Batinic-Haberle & Gayathri R. Devi. (2014) Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death. Free Radical Biology and Medicine 68, pages 302-314.
Crossref
Crossref
Chunyan Yang, Qianrong Li & Yong Li. (2014) Targeting Nuclear Receptors with Marine Natural Products. Marine Drugs 12:2, pages 601-635.
Crossref
Crossref
Carolin Mügge, Ruiqi Liu, Helmar Görls, Chiara Gabbiani, Elena Michelucci, Nadine Rüdiger, Joachim H. Clement, Luigi Messori & Wolfgang Weigand. (2014)
Novel platinum(
ii
) compounds with O,S bidentate ligands: synthesis, characterization, antiproliferative properties and biomolecular interactions
. Dalton Trans. 43:8, pages 3072-3086.
Crossref
Crossref
Andreas M. Loening & Zachary F. Walls. 2014. Engineering in Translational Medicine. Engineering in Translational Medicine
203
231
.
Pawel PaskoKarolina Bukowska-StrakovaJoanna Gdula-ArgasinskaMalgorzata Tyszka-Czochara. (2013)
Rutabaga
(Brassica napus
L. var.
napobrassica)
Seeds, Roots, and Sprouts: A Novel Kind of Food with Antioxidant Properties and Proapoptotic Potential in Hep G2 Hepatoma Cell Line
. Journal of Medicinal Food 16:8, pages 749-759.
Crossref
Crossref
Giuseppe Arrabito, Clelia Galati, Sabrina Castellano & Bruno Pignataro. (2013) Luminometric sub-nanoliter droplet-to-droplet array (LUMDA) and its application to drug screening by phase I metabolism enzymes. Lab Chip 13:1, pages 68-72.
Crossref
Crossref
A. Caporale, L. Gesiot, M. Sturlese, A. Wittelsberger, S. Mammi & E. Peggion. (2011) Design, conformational studies and analysis of structure–function relationships of PTH (1–11) analogues: the essential role of Val in position 2. Amino Acids 43:1, pages 207-218.
Crossref
Crossref
Marleen Keyaerts, Isabel Remory, Vicky Caveliers, Karine Breckpot, Tomas J. Bos, Jan Poelaert, Axel Bossuyt & Tony Lahoutte. (2012) Inhibition of Firefly Luciferase by General Anesthetics: Effect on In Vitro and In Vivo Bioluminescence Imaging. PLoS ONE 7:1, pages e30061.
Crossref
Crossref
Poncho L. Meisenheimer, H. Tetsuo Uyeda, Dongping Ma, Mary Sobol, Mark G. McDougall, Cesear Corona, Dan Simpson, Dieter H. Klaubert & James J. Cali. (2011) Proluciferin Acetals as Bioluminogenic Substrates for Cytochrome P450 Activity and Probes for CYP3A Inhibition. Drug Metabolism and Disposition 39:12, pages 2403-2410.
Crossref
Crossref
Tatiana Rozhko, Lidia Bondareva, Olga Mogilnaya, Galina Vydryakova, Alexander Bolsunovsky, Devard Stom & Nadezhda Kudryasheva. (2010) Detoxification of AM-241 solutions by humic substances: bioluminescent monitoring. Analytical and Bioanalytical Chemistry 400:2, pages 329-334.
Crossref
Crossref
Andrea Caporale, Mattia Sturlese, Elisabetta Schievano, Stefano Mammi & Evaristo Peggion. (2010) Synthesis and structural studies of new analogues of PTH(1–11) containing Cα-tetra-substituted amino acids in position 8. Amino Acids 39:5, pages 1369-1379.
Crossref
Crossref
Pierre ReschiglianKendrick Turner, Nilesh Raut, Patrizia Pasini, Sylvia Daunert, Elisa Michelini, Luca Cevenini, Laura Mezzanotte & Aldo Roda. 2010. Chemiluminescence and Bioluminescence. Chemiluminescence and Bioluminescence
511
542
.
Elisa Michelini, Luca Cevenini, Laura Mezzanotte, Andrea Coppa & Aldo Roda. (2010) Cell-based assays: fuelling drug discovery. Analytical and Bioanalytical Chemistry 398:1, pages 227-238.
Crossref
Crossref
Andrea Caporale, Barbara Biondi, Elisabetta Schievano, Angela Wittelsberger, Stefano Mammi & Evaristo Peggion. (2009) Structure–function relationship studies of PTH(1–11) analogues containing D-amino acids. European Journal of Pharmacology 611:1-3, pages 1-7.
Crossref
Crossref
Ryan MacArthur, William Leister, Henrike Veith, Paul Shinn, Noel Southall, Christopher P. Austin, James Inglese & Douglas S. Auld. (2009) Monitoring Compound Integrity With Cytochrome P450 Assays and qHTS. SLAS Discovery 14:5, pages 538-546.
Crossref
Crossref
Kalvin J. Gregory & Yeh Sun. (2009) Reduction of sample evaporation in small volume microplate luminescence assays. Analytical Biochemistry 387:2, pages 321-323.
Crossref
Crossref
Douglas S. Auld, Ya-Qin Zhang, Noel T. Southall, Ganesha Rai, Marc Landsman, Jennifer MacLure, Daniel Langevin, Craig J. Thomas, Christopher P. Austin & James Inglese. (2009) A Basis for Reduced Chemical Library Inhibition of Firefly Luciferase Obtained from Directed Evolution. Journal of Medicinal Chemistry 52:5, pages 1450-1458.
Crossref
Crossref
Liang Shan, Renshu Zhang, Wanghai Zhang, Edward Lee, Rajagopalan Sridhar, Elizabeth G. Snyderwine & Paul C. Wang. (2008) Image-based evaluation of the molecular events underlying HC11 mammary epithelial cell differentiation. Analytical Biochemistry 382:2, pages 122-128.
Crossref
Crossref