Citations (26)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (1)
Angelo Spinello, Ida Ritacco & Alessandra Magistrato. (2019) Recent advances in computational design of potent aromatase inhibitors: open-eye on endocrine-resistant breast cancers. Expert Opinion on Drug Discovery 14:10, pages 1065-1076.
Read now
Read now
Articles from other publishers (25)
Ali Abdelkrim, Abdelkrim Bouramoul, Imene Zenbout & Said Brahimi. (2023) Evaluating the Effectiveness of Machine Learning Models for Classifying Chemical Inhibitors: A Case Study of Aromatase Inhibitors and Pubchem's Molecular Fingerprint Descriptors. Evaluating the Effectiveness of Machine Learning Models for Classifying Chemical Inhibitors: A Case Study of Aromatase Inhibitors and Pubchem's Molecular Fingerprint Descriptors.
Fatemeh Bamdad, Hossein Farrokhpour, Mahmud Ashrafizaadeh & Bijan Najafi. (2022) Decomposition of the interaction energy of several flavonoids with Escherichia coli DNA Gyr using the SAPT (DFT) method: The relation between the interaction energy components, ligand structure, and biological activity. Biochimica et Biophysica Acta (BBA) - General Subjects 1866:5, pages 130111.
Crossref
Crossref
Marialuigia Fantacuzzi, Marialucia Gallorini, Nicola Gambacorta, Alessandra Ammazzalorso, Zeineb Aturki, Marwa Balaha, Simone Carradori, Letizia Giampietro, Cristina Maccallini, Amelia Cataldi, Orazio Nicolotti, Rosa Amoroso & Barbara De Filippis. (2021) Design, Synthesis and Biological Evaluation of Aromatase Inhibitors Based on Sulfonates and Sulfonamides of Resveratrol. Pharmaceuticals 14:10, pages 984.
Crossref
Crossref
Derya Osmaniye, Şennur Görgülü, Begüm Nurpelin Sağlık, Serkan Levent, Yusuf Özkay & Zafer Asım Kaplancıklı. (2021) Design, synthesis, in vitro and in silico studies of some novel thiazole-dihydrofuran derivatives as aromatase inhibitors. Bioorganic Chemistry 114, pages 105123.
Crossref
Crossref
Alessandra Ammazzalorso, Marialucia Gallorini, Marialuigia Fantacuzzi, Nicola Gambacorta, Barbara De Filippis, Letizia Giampietro, Cristina Maccallini, Orazio Nicolotti, Amelia Cataldi & Rosa Amoroso. (2021) Design, synthesis and biological evaluation of imidazole and triazole-based carbamates as novel aromatase inhibitors. European Journal of Medicinal Chemistry 211, pages 113115.
Crossref
Crossref
Muhamad Mustafa, Ahmed El-Kardocy & Yaser A Mostafa. (2021) Development of new hetero-steroid hybrids with antiproliferative activity against MCF-7 breast cancer cells. Monatshefte für Chemie - Chemical Monthly 152:1, pages 137-149.
Crossref
Crossref
Nilanjan Adhikari, Sandip Kumar Baidya & Tarun Jha. (2020) Effective anti-aromatase therapy to battle against estrogen-mediated breast cancer: Comparative SAR/QSAR assessment on steroidal aromatase inhibitors. European Journal of Medicinal Chemistry 208, pages 112845.
Crossref
Crossref
Mebarka OUASSAF, Salah BELAIDI, İmane BENBRAHİM, Houmam BELAİDİ & Samir CHTİTA. (2020) Quantitative Structure-Activity Relationships of 1.2.3 Triazole Derivatives as Aromatase Inhibition Activity. Turkish Computational and Theoretical Chemistry 4:1, pages 1-11.
Crossref
Crossref
Jessica Caciolla, Angelo Spinello, Silvia Martini, Alessandra Bisi, Nadia Zaffaroni, Silvia Gobbi & Alessandra Magistrato. (2020) Targeting Orthosteric and Allosteric Pockets of Aromatase via Dual-Mode Novel Azole Inhibitors. ACS Medicinal Chemistry Letters 11:5, pages 732-739.
Crossref
Crossref
Mariangela Garofalo, Giovanni Grazioso, Andrea Cavalli & Jacopo Sgrignani. (2020) How Computational Chemistry and Drug Delivery Techniques Can Support the Development of New Anticancer Drugs. Molecules 25:7, pages 1756.
Crossref
Crossref
Ali Ramazani, Hamed Sadighian, Farideh Gouranlou & Sang W. Joo. (2020) Syntheses and Biological Activities of triazole-based Sulfonamides. Current Organic Chemistry 23:21, pages 2319-2349.
Crossref
Crossref
Laxmi Banjare, Sant Kumar Verma, Akhlesh Kumar Jain & Suresh Thareja. (2019) Structure Guided Molecular Docking Assisted Alignment Dependent 3DQSAR Study on Steroidal Aromatase Inhibitors (SAIs) as Anti-breast Cancer Agents. Letters in Drug Design & Discovery 16:7, pages 808-817.
Crossref
Crossref
Angelo Spinello, Silvia Martini, Federico Berti, Marzia Pennati, Matic Pavlin, Jacopo Sgrignani, Giovanni Grazioso, Giorgio Colombo, Nadia Zaffaroni & Alessandra Magistrato. (2019) Rational design of allosteric modulators of the aromatase enzyme: An unprecedented therapeutic strategy to fight breast cancer. European Journal of Medicinal Chemistry 168, pages 253-262.
Crossref
Crossref
Zafer Sahin, Merve Ertas, Barkın Berk, Sevde Nur Biltekin, Leyla Yurttas & Seref Demirayak. (2018) Studies on non-steroidal inhibitors of aromatase enzyme; 4-(aryl/heteroaryl)-2-(pyrimidin-2-yl)thiazole derivatives. Bioorganic & Medicinal Chemistry 26:8, pages 1986-1995.
Crossref
Crossref
Angela Stefanachi, Francesco Leonetti, Leonardo Pisani, Marco Catto & Angelo Carotti. (2018) Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds. Molecules 23:2, pages 250.
Crossref
Crossref
Ratchanok Pingaew, Prasit Mandi, Veda Prachayasittikul, Supaluk Prachayasittikul, Somsak Ruchirawat & Virapong Prachayasittikul. (2018) Synthesis, molecular docking, and QSAR study of sulfonamide-based indoles as aromatase inhibitors. European Journal of Medicinal Chemistry 143, pages 1604-1615.
Crossref
Crossref
Alessandra Magistrato, Jacopo Sgrignani, Rolf Krause & Andrea Cavalli. (2017) Single or Multiple Access Channels to the CYP450s Active Site? An Answer from Free Energy Simulations of the Human Aromatase Enzyme. The Journal of Physical Chemistry Letters 8:9, pages 2036-2042.
Crossref
Crossref
Debashis Ghosh, Jessica Lo & Chinaza Egbuta. (2016) Recent Progress in the Discovery of Next Generation Inhibitors of Aromatase from the Structure–Function Perspective. Journal of Medicinal Chemistry 59:11, pages 5131-5148.
Crossref
Crossref
Jacopo Sgrignani, Marcella Iannuzzi & Alessandra Magistrato. (2015) Role of Water in the Puzzling Mechanism of the Final Aromatization Step Promoted by the Human Aromatase Enzyme. Insights from QM/MM MD Simulations. Journal of Chemical Information and Modeling 55:10, pages 2218-2226.
Crossref
Crossref
Ratchanok Pingaew, Veda Prachayasittikul, Prasit Mandi, Chanin Nantasenamat, Supaluk Prachayasittikul, Somsak Ruchirawat & Virapong Prachayasittikul. (2015) Synthesis and molecular docking of 1,2,3-triazole-based sulfonamides as aromatase inhibitors. Bioorganic & Medicinal Chemistry 23:13, pages 3472-3480.
Crossref
Crossref
Wei Lv, Jinzhong Liu, Todd C. Skaar, David A. Flockhart & Mark Cushman. (2015) Design and Synthesis of Norendoxifen Analogues with Dual Aromatase Inhibitory and Estrogen Receptor Modulatory Activities. Journal of Medicinal Chemistry 58:6, pages 2623-2648.
Crossref
Crossref
Apilak Worachartcheewan, Prasit Mandi, Virapong Prachayasittikul, Alla P. Toropova, Andrey A. Toropov & Chanin Nantasenamat. (2014) Large-scale QSAR study of aromatase inhibitors using SMILES-based descriptors. Chemometrics and Intelligent Laboratory Systems 138, pages 120-126.
Crossref
Crossref
Jacopo Sgrignani, Marta Bon, Giorgio Colombo & Alessandra Magistrato. (2014) Computational Approaches Elucidate the Allosteric Mechanism of Human Aromatase Inhibition: A Novel Possible Route to Small-Molecule Regulation of CYP450s Activities?. Journal of Chemical Information and Modeling 54:10, pages 2856-2868.
Crossref
Crossref
Angelo Danilo Favia, Orazio Nicolotti, Angela Stefanachi, Francesco Leonetti & Angelo Carotti. (2013) ChemInform Abstract: Computational Methods for the Design of Potent Aromatase Inhibitors. ChemInform 44:35.
Crossref
Crossref
Elaine F. F. da Cunha, José E. Resende, Tanos C. C. Franca, Mateus Aquino Gonçalves, Felipe R. de Souza, Letícia Santos-Garcia & Teodorico C. Ramalho. (2013) Molecular Modeling Studies of Piperidine Derivatives as New Acetylcholinesterase Inhibitors against Neurodegenerative Diseases. Journal of Chemistry 2013, pages 1-7.
Crossref
Crossref