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Expert Opinion on Drug Discovery Volume 8, 2013 - Issue 4
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Novel avenues for Clostridium difficile infection drug discovery

Mario ZuccaUniversity of Torino, at S. Luigi Gonzaga Hospital, Department of Clinical and Biological Sciences, Regione Gonzole 10, Orbassano (To) 10043, Italy+39 0116705427; +39 0112365427; [email protected]
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Sara ScuteraUniversity of Torino, Department of Public Health and Paediatric Sciences, V. Santena 9, Torino 10126, Italy
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Dianella SavoiaUniversity of Torino, at S. Luigi Gonzaga Hospital, Department of Clinical and Biological Sciences, Regione Gonzole 10, Orbassano (To) 10043, Italy+39 0116705427; +39 0112365427; [email protected]
Pages 459-477 | Published online: 22 Feb 2013

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Shakhinur Islam Mondal, Lorraine A. Draper, R Paul Ross & Colin Hill. (2020) Bacteriophage endolysins as a potential weapon to combat Clostridioides difficile infection. Gut Microbes 12:1.
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Articles from other publishers (12)

Janet Y. Nale, Anisha M. Thanki, Srwa J. Rashid, Jinyu Shan, Gurinder K. Vinner, Ahmed S. A. Dowah, Jeffrey K. J. Cheng, Thomas Sicheritz-Pontén & Martha R. J. Clokie. (2022) Diversity, Dynamics and Therapeutic Application of Clostridioides difficile Bacteriophages. Viruses 14:12, pages 2772.
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Krzysztof Hinc, Monika Kabała, Adam Iwanicki, Gajane Martirosian, Alessandro Negri & Michał Obuchowski. (2021) Complete genome sequence of the newly discovered temperate Clostridioides difficile bacteriophage phiCDKH01 of the family Siphoviridae. Archives of Virology 166:8, pages 2305-2310.
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Shakhinur Islam Mondal, Arzuba Akter, Lorraine A. Draper, R. Paul Ross & Colin Hill. (2021) Characterization of an Endolysin Targeting Clostridioides difficile That Affects Spore Outgrowth. International Journal of Molecular Sciences 22:11, pages 5690.
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Janet Y. Nale, Mahananda Chutia, Jeffrey K. J. Cheng & Martha R. J. Clokie. (2020) Refining the Galleria mellonella Model by Using Stress Marker Genes to Assess Clostridioides difficile Infection and Recuperation during Phage Therapy. Microorganisms 8:9, pages 1306.
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Janet Nale, Tamsin Redgwell, Andrew Millard & Martha Clokie. (2018) Efficacy of an Optimised Bacteriophage Cocktail to Clear Clostridium difficile in a Batch Fermentation Model. Antibiotics 7:1, pages 13.
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Lok-Hang Yan, Antoine Le Roux, Kumaraswamy Boyapelly, Anne-Marie Lamontagne, Marie-Ann Archambault, Frédéric Picard-Jean, David Lalonde-Seguin, Emilie St-Pierre, Rafael J. Najmanovich, Louis-Charles Fortier, Daniel Lafontaine & Éric Marsault. (2018) Purine analogs targeting the guanine riboswitch as potential antibiotics against Clostridioides difficile. European Journal of Medicinal Chemistry 143, pages 755-768.
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Sophie Fehlbaum, Christophe Chassard, Sophie Annick Poeker, Muriel Derrien, Candice Fourmestraux & Christophe Lacroix. (2016) Clostridium difficile colonization and antibiotics response in PolyFermS continuous model mimicking elderly intestinal fermentation. Gut Pathogens 8:1.
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Janet Y. Nale, Mahananda Chutia, Philippa Carr, Peter T. Hickenbotham & Martha R. J. Clokie. (2016) ‘Get in Early’; Biofilm and Wax Moth (Galleria mellonella) Models Reveal New Insights into the Therapeutic Potential of Clostridium difficile Bacteriophages. Frontiers in Microbiology 7.
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Janet Y. Nale, Janice Spencer, Katherine R. Hargreaves, Anthony M. Buckley, Przemysław Trzepiński, Gillian R. Douce & Martha R. J. Clokie. (2016) Bacteriophage Combinations Significantly Reduce Clostridium difficile Growth In Vitro and Proliferation In Vivo . Antimicrobial Agents and Chemotherapy 60:2, pages 968-981.
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Alain Dublanchet. (2014) Qu’est-ce que la phagothérapie ?. Hegel N° 4:4, pages 354-370.
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Alain Dublanchet. (2014) Qu’est-ce que la phagothérapie ?. Hegel N° 4:4, pages 354-370.
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Katherine R. Hargreaves & Martha R. J. Clokie. (2014) Clostridium difficile phages: still difficult?. Frontiers in Microbiology 5.
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