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Carrie J. Lovitt, Todd B. Shelper & Vicky M. Avery. (2016) Cancer drug discovery: recent innovative approaches to tumor modeling. Expert Opinion on Drug Discovery 11:9, pages 885-894.
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B. W. M. Thilini J. Basnayake, Paul Leo, Sudha Rao, Sarju Vasani, Lizbeth Kenny, Nikolas K. Haass & Chamindie Punyadeera. (2023) Head and neck cancer patient-derived tumouroid cultures: opportunities and challenges. British Journal of Cancer 128:10, pages 1807-1818.
Crossref
Crossref
Luiza Martins Nascentes Melo, Suresh Kumar, Valeria Riess, Krystina J. Szylo, Robin Eisenburger, Dirk Schadendorf, Jessalyn M. Ubellacker & Alpaslan Tasdogan. (2023) Advancements in melanoma cancer metastasis models. Pigment Cell & Melanoma Research 36:2, pages 206-223.
Crossref
Crossref
SANDRA STICKLER, BARBARA RATH, MAXIMILIAN HOCHMAIR, CLEMENS LANG, LUKAS WEIGL & GERHARD HAMILTON. (2023) Changes of protein expression during tumorosphere formation of small cell lung cancer circulating tumor cells. Oncology Research 31:1, pages 13-22.
Crossref
Crossref
Akshay Akshay, Mitali Katoch, Masoud Abedi, Navid Shekarchizadeh, Mustafa Besic, Fiona C Burkhard, Alex Bigger-Allen, Rosalyn M Adam, Katia Monastyrskaya & Ali Hashemi Gheinani. (2023) SpheroScan: a user-friendly deep learning tool for spheroid image analysis. GigaScience 12.
Crossref
Crossref
Kazumasa Sekihara, Hidetomo Himuro, Nao Saito, Yukihide Ota, Taku Kouro, Yohsuke Kusano, Shinichi Minohara, Ryoichi Hirayama, Hiroyuki Katoh, Tetsuro Sasada & Daisuke Hoshino. (2022) Evaluation of X-ray and carbon-ion beam irradiation with chemotherapy for the treatment of cervical adenocarcinoma cells in 2D and 3D cultures. Cancer Cell International 22:1.
Crossref
Crossref
Elisabetta Michielon, Tanja D. de Gruijl & Susan Gibbs. (2022) From simplicity to complexity in current melanoma models. Experimental Dermatology 31:12, pages 1818-1836.
Crossref
Crossref
Maximiliane Wußmann, Florian Kai Groeber-Becker, Sabrina Riedl, Dina Alihodzic, Daniel Padaric, Lisa Gerlitz, Alexander Stallinger, Bernadette Liegl-Atzwanger, Dagmar Zweytick & Beate Rinner. (2022) In Model, In Vitro and In Vivo Killing Efficacy of Antitumor Peptide RDP22 on MUG-Mel2, a Patient Derived Cell Line of an Aggressive Melanoma Metastasis. Biomedicines 10:11, pages 2961.
Crossref
Crossref
Anna Leikeim, Maximiliane Wußmann, Freia F. Schmidt, Nuno G. B. Neto, Franziska Benz, Kendra Tiltmann, Corinna Junger, Michael G. Monaghan, Bastian Schilling & Florian K. Groeber-Becker. (2022) A preclinical model of cutaneous melanoma based on reconstructed human epidermis. Scientific Reports 12:1.
Crossref
Crossref
Preety Rawal, Dinesh Tripathi, Vikrant Nain & Savneet Kaur. (2022) VEGF‑mediated tumour growth and EMT in 2D and 3D cell culture models of hepatocellular carcinoma. Oncology Letters 24:3.
Crossref
Crossref
Heike Chauvistré, Batool Shannan, Sheena M. Daignault-Mill, Robert J. Ju, Daniel Picard, Stefanie Egetemaier, Renáta Váraljai, Christine S. Gibhardt, Antonio Sechi, Farnusch Kaschani, Oliver Keminer, Samantha J. Stehbens, Qin Liu, Xiangfan Yin, Kirujan Jeyakumar, Felix C. E. Vogel, Clemens Krepler, Vito W. Rebecca, Linda Kubat, Smiths S. Lueong, Jan Forster, Susanne Horn, Marc Remke, Michael Ehrmann, Annette Paschen, Jürgen C. Becker, Iris Helfrich, Daniel Rauh, Markus Kaiser, Sheraz Gul, Meenhard Herlyn, Ivan Bogeski, José Neptuno Rodríguez-López, Nikolas K. Haass, Dirk Schadendorf & Alexander Roesch. (2022) Persister state-directed transitioning and vulnerability in melanoma. Nature Communications 13:1.
Crossref
Crossref
Mohammad A. Rezania, Azadeh Eghtedari, Masoumeh F. Taha, Ali M. Ardekani & Arash Javeri. (2022) A novel role for aspirin in enhancing the reprogramming function of miR‐302/367 cluster and breast tumor suppression. Journal of Cellular Biochemistry 123:6, pages 1077-1090.
Crossref
Crossref
Ryan J. Murphy, Alexander P. Browning, Gency Gunasingh, Nikolas K. Haass & Matthew J. Simpson. (2022) Designing and interpreting 4D tumour spheroid experiments. Communications Biology 5:1.
Crossref
Crossref
Jia Lin Teh, Siti Fairus Abdul Rahman, Gregory Domnic, Lengishwarra Satiyasilan, Nelson Jeng Yeou Chear, Darshan Singh & Nethia Mohana-Kumaran. (2021) Rapid spheroid assays in a 3-dimensional cell culture chip. BMC Research Notes 14:1.
Crossref
Crossref
Alexander P Browning, Jesse A Sharp, Ryan J Murphy, Gency Gunasingh, Brodie Lawson, Kevin Burrage, Nikolas K Haass & Matthew Simpson. (2021) Quantitative analysis of tumour spheroid structure. eLife 10.
Crossref
Crossref
Mariana Matias, Jacinta O. Pinho, Maria João Penetra, Gonçalo Campos, Catarina Pinto Reis & Maria Manuela Gaspar. (2021) The Challenging Melanoma Landscape: From Early Drug Discovery to Clinical Approval. Cells 10:11, pages 3088.
Crossref
Crossref
Sabrina Cappello, Hsu-Min Sung, Christian Ickes, Christine S. Gibhardt, Adina Vultur, Hilal Bhat, Zhongwen Hu, Patricia Brafford, Andreas Denger, Ioana Stejerean-Todoran, Rixa-Mareike Köhn, Verena Lorenz, Nicolas Künzel, Gabriela Salinas, Hedwig Stanisz, Tobias Legler, Peter Rehling, Michael P. Schön, Karl S. Lang, Volkhard Helms, Meenhard Herlyn, Markus Hoth, Carsten Kummerow & Ivan Bogeski. (2021) Protein Signatures of NK Cell–Mediated Melanoma Killing Predict Response to Immunotherapies. Cancer Research 81:21, pages 5540-5554.
Crossref
Crossref
Gregory Domnic, Nelson Jeng-Yeou Chear, Siti Fairus Abdul Rahman, Surash Ramanathan, Kwok-Wai Lo, Darshan Singh & Nethia Mohana-Kumaran. (2021) Combinations of indole based alkaloids from Mitragyna speciosa (Kratom) and cisplatin inhibit cell proliferation and migration of nasopharyngeal carcinoma cell lines. Journal of Ethnopharmacology 279, pages 114391.
Crossref
Crossref
Constanze Buhrmann, Ajaikumar B. Kunnumakkara, Aviral Kumar, Marek Samec, Peter Kubatka, Bharat B. Aggarwal & Mehdi Shakibaei. (2021) Multitargeting Effects of Calebin A on Malignancy of CRC Cells in Multicellular Tumor Microenvironment. Frontiers in Oncology 11.
Crossref
Crossref
Ruby Gupta & Deepika Sharma. (2021) (Carboxymethyl-stevioside)-coated magnetic dots for enhanced magnetic hyperthermia and improved glioblastoma treatment. Colloids and Surfaces B: Biointerfaces 205, pages 111870.
Crossref
Crossref
Loredana Spoerri, Gency Gunasingh & Nikolas K. Haass. (2021) Fluorescence-Based Quantitative and Spatial Analysis of Tumour Spheroids: A Proposed Tool to Predict Patient-Specific Therapy Response. Frontiers in Digital Health 3.
Crossref
Crossref
Wang Jin, Loredana Spoerri, Nikolas K. Haass & Matthew J. Simpson. (2021) Mathematical Model of Tumour Spheroid Experiments with Real-Time Cell Cycle Imaging. Bulletin of Mathematical Biology 83:5.
Crossref
Crossref
Se Jik Han, Sangwoo Kwon & Kyung Sook Kim. (2021) Challenges of applying multicellular tumor spheroids in preclinical phase. Cancer Cell International 21:1.
Crossref
Crossref
Kalaivani Muniandy, Zuhaida Asra Ahmad, Sylvia Annabel Dass, Shaharum Shamsuddin, Nethia Mohana Kumaran & Venugopal Balakrishnan. (2021) Growth and Invasion of 3D Spheroid Tumor of HeLa and CasKi Cervical Cancer Cells. Oncologie 23:2, pages 279-291.
Crossref
Crossref
Patricia Basurto‐Lozada, Christian Molina‐Aguilar, Carolina Castaneda‐Garcia, Martha Estefania Vázquez‐Cruz, Omar Isaac Garcia‐Salinas, Alethia Álvarez‐Cano, Héctor Martínez‐Said, Rodrigo Roldán‐Marín, David J. Adams, Patricia A. Possik & Carla Daniela Robles‐Espinoza. (2020) Acral lentiginous melanoma: Basic facts, biological characteristics and research perspectives of an understudied disease. Pigment Cell & Melanoma Research 34:1, pages 59-71.
Crossref
Crossref
Randal K. Gregg. 2021. Melanoma. Melanoma
1
21
.
Priscila Ausina, Jessica R. Branco, Thainá M. Demaria, Amanda M. Esteves, João Gabriel B. Leandro, Alan C. Ochioni, Ana Paula M. Mendonça, Fernando L. Palhano, Marcus F. Oliveira, Wassim Abou-Kheir, Mauro Sola-Penna & Patricia Zancan. (2020) Acetylsalicylic acid and salicylic acid present anticancer properties against melanoma by promoting nitric oxide-dependent endoplasmic reticulum stress and apoptosis. Scientific Reports 10:1.
Crossref
Crossref
Siti Fairus Abdul Rahman, Kalaivani Muniandy, Yong Kit Soo, Elvin Yu Huai Tiew, Ke Xin Tan, Timothy E. Bates & Nethia Mohana-Kumaran. (2020) Co-inhibition of BCL-XL and MCL-1 with selective BCL-2 family inhibitors enhances cytotoxicity of cervical cancer cell lines. Biochemistry and Biophysics Reports 22, pages 100756.
Crossref
Crossref
Jessica Gonçalves, Michael F. Emmons, Fernanda Faião‐Flores, Andrew E. Aplin, J. William Harbour, Jonathan D. Licht, Márcia R. Wink & Keiran S. M. Smalley. (2019) Decitabine limits escape from MEK inhibition in uveal melanoma. Pigment Cell & Melanoma Research 33:3, pages 507-514.
Crossref
Crossref
Moslem Hoseinbeyki, Masoumeh F. Taha & Arash Javeri. (2020) miR‐16 enhances miR‐302/367‐induced reprogramming and tumor suppression in breast cancer cells. IUBMB Life 72:5, pages 1075-1086.
Crossref
Crossref
Shi Xiang Benedict Lian, Kwok-Wai Lo, Soo-Beng Alan Khoo & Nethia Mohana-Kumaran. (2020) Single Agent and Synergistic Activity of Maritoclax with ABT-263 in Nasopharyngeal Carcinoma (NPC) Cell Lines. Tropical Life Sciences Research 31:3, pages 1-13.
Crossref
Crossref
Syed A.A. Rizvi, Yasser Shahzad, Ayman M. Saleh & Nawshad Muhammad. (2020) Dose Issues in Cancer Chemotherapy. Oncology 98:8, pages 520-527.
Crossref
Crossref
Nicholas M. Wragg, Diogo Mosqueira, Lia Blokpeol‐Ferreras, Andrew Capel, Darren J. Player, Neil R. W. Martin, Yang Liu & Mark P. Lewis. (2019) Development of a 3D Tissue‐Engineered Skeletal Muscle and Bone Co‐culture System. Biotechnology Journal 15:1, pages 1900106.
Crossref
Crossref
Julia Klicks, Christoph Maßlo, Andreas Kluth, Rüdiger Rudolf & Mathias Hafner. (2019) A novel spheroid-based co-culture model mimics loss of keratinocyte differentiation, melanoma cell invasion, and drug-induced selection of ABCB5-expressing cells. BMC Cancer 19:1.
Crossref
Crossref
Marta Osrodek, Mariusz Hartman & Malgorzata Czyz. (2019) Physiologically Relevant Oxygen Concentration (6% O2) as an Important Component of the Microenvironment Impacting Melanoma Phenotype and Melanoma Response to Targeted Therapeutics In Vitro. International Journal of Molecular Sciences 20:17, pages 4203.
Crossref
Crossref
Mehdi Haghi, Masoumeh F. Taha & Arash Javeri. (2019) Suppressive effect of exogenous miR‐16 and miR‐34a on tumorigenesis of breast cancer cells. Journal of Cellular Biochemistry 120:8, pages 13342-13353.
Crossref
Crossref
Dajiang Guo, Goldie Y.L. Lui, Siew Li Lai, James S. Wilmott, Shweta Tikoo, Louise A. Jackett, Camelia Quek, Darren L. Brown, Danae M. Sharp, Rain Y.Q. Kwan, Diego Chacon, Jason H. Wong, Dominik Beck, Michelle Geldermalsen, Jeff Holst, John F. Thompson, Graham J. Mann, Richard A. Scolyer, Jennifer L. Stow, Wolfgang Weninger, Nikolas K. Haass & Kimberley A. Beaumont. (2019)
RAB27A promotes melanoma cell invasion and metastasis
via
regulation of pro‐invasive exosomes
. International Journal of Cancer 144:12, pages 3070-3085.
Crossref
Crossref
Erinna F. Lee, Tiffany J. Harris, Sharon Tran, Marco Evangelista, Surein Arulananda, Thomas John, Celeste Ramnac, Chloe Hobbs, Haoran Zhu, Gency Gunasingh, David Segal, Andreas Behren, Jonathan Cebon, Alexander Dobrovic, John M. Mariadason, Andreas Strasser, Leona Rohrbeck, Nikolas K. Haass, Marco J. Herold & W. Douglas Fairlie. (2019) BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival. Cell Death & Disease 10:5.
Crossref
Crossref
Bahareh Ramezankhani, Masoumeh F. Taha & Arash Javeri. (2018) Vitamin C counteracts miR‐302/367‐induced reprogramming of human breast cancer cells and restores their invasive and proliferative capacity. Journal of Cellular Physiology 234:3, pages 2672-2682.
Crossref
Crossref
Mine Altunbek, Demet Çetin, Zekiye Suludere & Mustafa Çulha. (2019) Surface-enhanced Raman spectroscopy based 3D spheroid culture for drug discovery studies. Talanta 191, pages 390-399.
Crossref
Crossref
Robert J. Ju, Samantha J. Stehbens & Nikolas K. Haass. (2018) The Role of Melanoma Cell-Stroma Interaction in Cell Motility, Invasion, and Metastasis. Frontiers in Medicine 5.
Crossref
Crossref
Jingyun Ma, Na Li, Yachen Wang, Liang Wang, Wenjuan Wei, Liming Shen, Yu Sun, Yang Jiao, Weigong Chen & Jing Liu. (2018) Engineered 3D tumour model for study of glioblastoma aggressiveness and drug evaluation on a detachably assembled microfluidic device. Biomedical Microdevices 20:3.
Crossref
Crossref
Ileabett M Echevarría‐Vargas, Patricia I Reyes‐Uribe, Adam N Guterres, Xiangfan Yin, Andrew V Kossenkov, Qin Liu, Gao Zhang, Clemens Krepler, Chaoran Cheng, Zhi Wei, Rajasekharan Somasundaram, Giorgos Karakousis, Wei Xu, Jennifer JD Morrissette, Yiling Lu, Gordon B Mills, Ryan J Sullivan, Miao Benchun, Dennie T Frederick, Genevieve Boland, Keith T Flaherty, Ashani T Weeraratna, Meenhard Herlyn, Ravi Amaravadi, Lynn M Schuchter, Christin E Burd, Andrew E Aplin, Xiaowei Xu & Jessie Villanueva. (2018)
Co‐targeting
BET
and
MEK
as salvage therapy for
MAPK
and checkpoint inhibitor‐resistant melanoma
. EMBO Molecular Medicine 10:5.
Crossref
Crossref
Stuart J. Gallagher, Dilini Gunatilake, Kimberley A. Beaumont, Danae M. Sharp, Jessamy C. Tiffen, Anja Heinemann, Wolfgang Weninger, Nikolas K. Haass, James S. Wilmott, Jason Madore, Peter M. Ferguson, Helen Rizos & Peter Hersey. (2018) HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma. International Journal of Cancer 142:9, pages 1926-1937.
Crossref
Crossref
Hongxu Lu & Martina H. Stenzel. (2018) Multicellular Tumor Spheroids (MCTS) as a 3D In Vitro Evaluation Tool of Nanoparticles. Small 14:13, pages 1702858.
Crossref
Crossref
Monica Gatti, Agnese Solari, Alessandra Pattarozzi, Chiara Campanella, Stefano Thellung, Lorella Maniscalco, Raffaella De Maria, Roberto Würth, Alessandro Corsaro, Adriana Bajetto, Alessandra Ratto, Angelo Ferrari, Antonio Daga, Federica Barbieri & Tullio Florio. (2018) In vitro and in vivo characterization of stem-like cells from canine osteosarcoma and assessment of drug sensitivity. Experimental Cell Research 363:1, pages 48-64.
Crossref
Crossref
А.Н. Чернов, Е.П. Баранцевич, Э.С. Галимова & М.М. Галагудза. (2018) Cell cultures of human malignant tumors in development of new anticancer therapies. Nauchno-prakticheskii zhurnal «Patogenez»:4(), pages 13-23.
Crossref
Crossref
Bryan E Strauss, Gissele Rolemberg Oliveira Silva, Igor de Luna Vieira, Otto Luiz Dutra Cerqueira, Paulo Roberto Del Valle, Ruan Felipe Vieira Medrano & Samir Andrade Mendonça. (2018) Perspectives for cancer immunotherapy mediated by p19Arf plus interferon-beta gene transfer. Clinics 73, pages e479s.
Crossref
Crossref
Juan Tornin, Francisco Hermida-Prado, Ranjit Singh Padda, M. Victoria Gonzalez, Carlos Alvarez-Fernandez, Veronica Rey, Lucia Martinez-Cruzado, Oscar Estupiñan, Sofia T. Menendez, Lucia Fernandez-Nevado, Aurora Astudillo, Juan P. Rodrigo, Fabrice Lucien, Yohan Kim, Hon S. Leong, Juana Maria Garcia-Pedrero & Rene Rodriguez. (2018) FUS-CHOP Promotes Invasion in Myxoid Liposarcoma through a SRC/FAK/RHO/ROCK-Dependent Pathway. Neoplasia 20:1, pages 44-56.
Crossref
Crossref
Nikolas K. Haass & Brian Gabrielli. (2017) Cell cycle-tailored targeting of metastatic melanoma: Challenges and opportunities. Experimental Dermatology 26:7, pages 649-655.
Crossref
Crossref
Arne Kienzle, Sven Kurch, Janine Schlöder, Carsten Berges, Robert Ose, Jonathan Schupp, Andrea Tuettenberg, Henning Weiss, Jennifer Schultze, Svenja Winzen, Meike Schinnerer, Kaloian Koynov, Markus Mezger, Nikolas K. Haass, Wolfgang Tremel & Helmut Jonuleit. (2017) Dendritic Mesoporous Silica Nanoparticles for pH-Stimuli-Responsive Drug Delivery of TNF-Alpha. Advanced Healthcare Materials 6:13, pages 1700012.
Crossref
Crossref
Krzysztof Klimkiewicz, Kazimierz Weglarczyk, Guillaume Collet, Maria Paprocka, Alan Guichard, Michal Sarna, Alicja Jozkowicz, Jozef Dulak, Tadeusz Sarna, Catherine Grillon & Claudine Kieda. (2017) A 3D model of tumour angiogenic microenvironment to monitor hypoxia effects on cell interactions and cancer stem cell selection. Cancer Letters 396, pages 10-20.
Crossref
Crossref
Prabu Siva Sankar, Mohd Firdaus Che Mat, Kalaivani Muniandy, Benedict Lian Shi Xiang, Phang Su Ling, Susan Ling Ling Hoe, Alan Soo-Beng Khoo & Nethia Mohana-Kumaran. (2017) Modeling nasopharyngeal carcinoma in three dimensions. Oncology Letters 13:4, pages 2034-2044.
Crossref
Crossref
Mitchell P. Levesque, Phil F. Cheng, Marieke I.G. Raaijmakers, Annalisa Saltari & Reinhard Dummer. (2017) Metastatic melanoma moves on: translational science in the era of personalized medicine. Cancer and Metastasis Reviews 36:1, pages 7-21.
Crossref
Crossref
Anastasia De Luca, Debora Carpanese, Maria Cristina Rapanotti, Tara Mayte Suarez Viguria, Maria Antonietta Forgione, Dante Rotili, Chiara Fulci, Egidio Iorio, Luigi Quintieri, Sergio Chimenti, Luca Bianchi, Antonio Rosato & Anna Maria Caccuri. (2017) The nitrobenzoxadiazole derivative MC3181 blocks melanoma invasion and metastasis. Oncotarget 8:9, pages 15520-15538.
Crossref
Crossref
Mitchell E. Fane, Yash Chhabra, David E.J. Hollingsworth, Jacinta L. Simmons, Loredana Spoerri, Tae Gyu Oh, Jagat Chauhan, Toby Chin, Lachlan Harris, Tracey J. Harvey, George E.O. Muscat, Colin R. Goding, Richard A Sturm, Nikolas K. Haass, Glen M. Boyle, Michael Piper & Aaron G. Smith. (2017) NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF. EBioMedicine 16, pages 63-75.
Crossref
Crossref
Tiziana Petrachi, Alessandra Romagnani, Adriana Albini, Caterina Longo, Giuseppe Argenziano, Giulia Grisendi, Massimo Dominici, Alessia Ciarrocchi & Katiuscia Dallaglio. (2016) Therapeutic potential of the metabolic modulator phenformin in targeting the stem cell compartment in melanoma. Oncotarget 8:4, pages 6914-6928.
Crossref
Crossref
Oddbjørn Straume & Cornelia Schuster. 2017. Biomarkers of the Tumor Microenvironment. Biomarkers of the Tumor Microenvironment
481
506
.
Loredana Spoerri, Kimberley A. Beaumont, Andrea Anfosso & Nikolas K. Haass. 2017. 3D Cell Culture. 3D Cell Culture
401
416
.
Miles C. Andrews, Joseph Cursons, Daniel G. Hurley, Matthew Anaka, Jonathan S. Cebon, Andreas Behren & Edmund J. Crampin. (2016) Systems analysis identifies miR-29b regulation of invasiveness in melanoma. Molecular Cancer 15:1.
Crossref
Crossref
Ayako Aihara, Natsuki Abe, Koichiro Saruhashi, Tatsuro Kanaki & Taito Nishino. (2016)
Novel 3‐D cell culture system for
in vitro
evaluation of anticancer drugs under anchorage‐independent conditions
. Cancer Science 107:12, pages 1858-1866.
Crossref
Crossref
Neda Bayat, Somayeh Ebrahimi-Barough, Abbas Norouzi-Javidan, Hooshang Saberi, Roksana Tajerian, Mohammad Mehdi Mokhtari Ardakan, Sadegh Shirian, Arman Ai & Jafar Ai. (2016) Apoptotic effect of atorvastatin in glioblastoma spheroids tumor cultured in fibrin gel. Biomedicine & Pharmacotherapy 84, pages 1959-1966.
Crossref
Crossref
Hamid Maadi, Abdolvahab Moshtaghian, Masoumeh Fakhr Taha, Seyed Javad Mowla, Asiye Kazeroonian, Nikolas K. Haass & Arash Javeri. (2016) Multimodal tumor suppression by miR-302 cluster in melanoma and colon cancer. The International Journal of Biochemistry & Cell Biology 81, pages 121-132.
Crossref
Crossref
Viktoria Planz, Claus-Michael Lehr & Maike Windbergs. (2016) In vitro models for evaluating safety and efficacy of novel technologies for skin drug delivery. Journal of Controlled Release 242, pages 89-104.
Crossref
Crossref
Batool Shannan, Andrea Watters, Quan Chen, Stefan Mollin, Markus Dörr, Eric Meggers, Xiaowei Xu, Phyllis A. Gimotty, Michela Perego, Ling Li, Joseph Benci, Clemens Krepler, Patricia Brafford, Jie Zhang, Zhi Wei, Gao Zhang, Qin Liu, Xiangfan Yin, Katherine L. Nathanson, Meenhard Herlyn & Adina Vultur. (2016) PIM kinases as therapeutic targets against advanced melanoma. Oncotarget 7:34, pages 54897-54912.
Crossref
Crossref
Kimberley A. Beaumont, David S. Hill, Sheena M. Daignault, Goldie Y.L. Lui, Danae M. Sharp, Brian Gabrielli, Wolfgang Weninger & Nikolas K. Haass. (2016) Cell Cycle Phase-Specific Drug Resistance as an Escape Mechanism of Melanoma Cells. Journal of Investigative Dermatology 136:7, pages 1479-1489.
Crossref
Crossref
Keith M. Giles, Rikki A.M. Brown, Clarissa Ganda, Melissa J. Podgorny, Patrick A. Candy, Larissa C. Wintle, Kirsty L. Richardson, Felicity C. Kalinowski, Lisa M. Stuart, Michael R. Epis, Nikolas K. Haass, Meenhard Herlyn & Peter J. Leedman. (2016) microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB. Oncotarget 7:22, pages 31663-31680.
Crossref
Crossref
Waseem Asghar, Rami El Assal, Hadi Shafiee, Sharon Pitteri, Ramasamy Paulmurugan & Utkan Demirci. (2015) Engineering cancer microenvironments for in vitro 3-D tumor models. Materials Today 18:10, pages 539-553.
Crossref
Crossref
Jessamy C. Tiffen, Dilini Gunatilake, Stuart J. Gallagher, Kavitha Gowrishankar, Anja Heinemann, Carleen Cullinane, Ken Dutton-Regester, Gulietta M. Pupo, Dario Strbenac, Jean Y. Yang, Jason Madore, Graham J. Mann, Nicholas K. Hayward, Grant A. McArthur, Fabian V. Filipp & Peter Hersey. (2015) Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes. Oncotarget 6:29, pages 27023-27036.
Crossref
Crossref
Nikolas K Haass. (2015) Dynamic tumor heterogeneity in melanoma therapy: how do we address this in a novel model system?. Melanoma Management 2:2, pages 93-95.
Crossref
Crossref
Nikolas K. Haass, Kimberley A. Beaumont, David S. Hill, Andrea Anfosso, Paulus Mrass, Marcia A. Munoz, Ichiko Kinjyo & Wolfgang Weninger. (2014) Real-time cell cycle imaging during melanoma growth, invasion, and drug response. Pigment Cell & Melanoma Research 27:5, pages 764-776.
Crossref
Crossref
Qian Wang, Kimberley A. Beaumont, Nicholas J. Otte, Josep Font, Charles G. Bailey, Michelle van Geldermalsen, Danae M. Sharp, Jessamy C. Tiffen, Renae M. Ryan, Mika Jormakka, Nikolas K. Haass, John E.J. Rasko & Jeff Holst. (2014) Targeting glutamine transport to suppress melanoma cell growth. International Journal of Cancer 135:5, pages 1060-1071.
Crossref
Crossref
D. Herrmann, J. R. W. Conway, C. Vennin, A. Magenau, W. E. Hughes, J. P. Morton & P. Timpson. (2014) Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment. Carcinogenesis 35:8, pages 1671-1679.
Crossref
Crossref
Akihiro Nishiguchi, Michiya Matsusaki, Yoshiya Asano, Hiroshi Shimoda & Mitsuru Akashi. (2014) Effects of angiogenic factors and 3D-microenvironments on vascularization within sandwich cultures. Biomaterials 35:17, pages 4739-4748.
Crossref
Crossref
Carrie Lovitt, Todd Shelper & Vicky Avery. (2014) Advanced Cell Culture Techniques for Cancer Drug Discovery. Biology 3:2, pages 345-367.
Crossref
Crossref
Vito W. Rebecca, Renato R. Massaro, Inna V. Fedorenko, Vernon K. Sondak, Alexander R. A. Anderson, Eunjung Kim, Ravi K. Amaravadi, Silvya S. Maria-Engler, Jane L. Messina, Geoffrey T. Gibney, Ragini R. Kudchadkar & Keiran S. M. Smalley. (2014)
Inhibition of autophagy enhances the effects of the AKT inhibitor MK-2206 when combined with paclitaxel and carboplatin in
BRAF
wild-type melanoma
. Pigment Cell & Melanoma Research 27:3, pages 465-478.
Crossref
Crossref
Kimberley Beaumont, Nethia Mohana-Kumaran & Nikolas Haass. (2013) Modeling Melanoma In Vitro and In Vivo. Healthcare 2:1, pages 27-46.
Crossref
Crossref
Cleidson P. Alves, Milene H. Moraes, Josane F. Sousa, Carmen Lucia S. Pontes, Anelisa Ramão, Satoru Yokoyama, Daniel M. Trindade, David E. Fisher & Enilza M. Espreafico. (2013) Myosin-Va Contributes to Manifestation of Malignant-Related Properties in Melanoma Cells. Journal of Investigative Dermatology 133:12, pages 2809-2812.
Crossref
Crossref
Justine R. Stehn, Nikolas K. Haass, Teresa Bonello, Melissa Desouza, Gregg Kottyan, Herbert Treutlein, Jun Zeng, Paula R.B.B. Nascimento, Vanessa B. Sequeira, Tanya L. Butler, Munif Allanson, Thomas Fath, Timothy A. Hill, Adam McCluskey, Galina Schevzov, Stephen J. Palmer, Edna C. Hardeman, David Winlaw, Vivienne E. Reeve, Ian Dixon, Wolfgang Weninger, Timothy P. Cripe & Peter W. Gunning. (2013) A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells. Cancer Research 73:16, pages 5169-5182.
Crossref
Crossref
Anja Kastl, Sandra Dieckmann, Kathrin Wähler, Timo Völker, Lena Kastl, Anna Lena Merkel, Adina Vultur, Batool Shannan, Klaus Harms, Matthias Ocker, Wolfgang J. Parak, Meenhard Herlyn & Eric Meggers. (2013) Rhenium Complexes with Visible-Light-Induced Anticancer Activity. ChemMedChem 8:6, pages 924-927.
Crossref
Crossref
D. Wroblewski, B. Mijatov, N. Mohana-Kumaran, F. Lai, S. J. Gallagher, N. K. Haass, X. D. Zhang & P. Hersey. (2012) The BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistance. Carcinogenesis 34:2, pages 237-247.
Crossref
Crossref
Keryn M. Lucas, Nethia Mohana-Kumaran, Diana Lau, Xu Dong Zhang, Peter Hersey, David C. Huang, Wolfgang Weninger, Nikolas K. Haass & John D. Allen. (2012) Modulation of NOXA and MCL-1 as a Strategy for Sensitizing Melanoma Cells to the BH3-Mimetic ABT-737. Clinical Cancer Research 18:3, pages 783-795.
Crossref
Crossref
Angela Boccarelli, Alessandra Pannunzio & Mauro Coluccia. 2011. Bioinorganic Medicinal Chemistry. Bioinorganic Medicinal Chemistry
175
196
.
Ranjna C. Dutta & Aroop K. Dutta. (2010) Comprehension of ECM-Cell dynamics: A prerequisite for tissue regeneration. Biotechnology Advances 28:6, pages 764-769.
Crossref
Crossref
Jessica Cedervall, Seema Jamil, Lina Prasmickaite, YenFu Cheng, Malihe Eskandarpour, Johan Hansson, Gunhild M. Mælandsmo, Ulrik Ringborg, Miklos Gulyas, He Suo Zhen, Lena Kanter & Lars Ährlund-Richter. (2009)
Species-Specific
In vivo
Engraftment of the Human BL Melanoma Cell Line Results in an Invasive Dedifferentiated Phenotype Not Present in Xenografts
. Cancer Research 69:9, pages 3746-3754.
Crossref
Crossref
Edward A. Pham, Won Jin Ho, Daniel T. Kamei & Benjamin M. Wu. (2009) Modification of the diphenylamine assay for cell quantification in three-dimensional biodegradable polymeric scaffolds. Journal of Biomedical Materials Research Part B: Applied Biomaterials 9999B, pages NA-NA.
Crossref
Crossref
Jessie Villanueva & Meenhard Herlyn. (2008) Melanoma and the tumor microenvironment. Current Oncology Reports 10:5, pages 439-446.
Crossref
Crossref
Olga Ohayon, Nidal Mawasi, Anna Pevzner, Ana Tryvitz, Tsvia Gildor, Mark Pines, Marcos Rojkind, Melia Paizi & Gadi Spira. (2008) Halofuginone upregulates the expression of heparanase in thioacetamide-induced liver fibrosis in rats. Laboratory Investigation 88:6, pages 627-633.
Crossref
Crossref