Advanced search
Publication Cover
Expert Opinion on Drug Discovery Volume 5, 2010 - Issue 5
Submit an article Journal homepage
271
Views
6
CrossRef citations to date
0
Altmetric
Reviews

Methods for the quantitative evaluation and prediction of CYP enzyme induction using human in vitro systems

Masashi Honma The University of Tokyo Hospital, Faculty of Medicine, Department of Pharmacy, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan +81 3 3815 5411; +81 3 3816 6159; [email protected]
,
Masanari Kozawa The University of Tokyo Hospital, Faculty of Medicine, Department of Pharmacy, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan +81 3 3815 5411; +81 3 3816 6159; [email protected]
&
Hiroshi Suzuki The University of Tokyo Hospital, Faculty of Medicine, Department of Pharmacy, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan +81 3 3815 5411; +81 3 3816 6159; [email protected]
Pages 491-511 | Published online: 22 Apr 2010

Citations (6)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Yong-Yeon Cho, Hyeon-Uk Jeong, Jeong-Han Kim & Hye Suk Lee. (2014) Effect of honokiol on the induction of drug-metabolizing enzymes in human hepatocytes. Drug Design, Development and Therapy 8, pages 2137-2145.
Read now

Articles from other publishers (5)

Yoshiyuki Ohno, Toyohito Oriyama, Akira Honda, Mineo Kurokawa & Tappei Takada. (2023) Induction of CYP3A activity by dexamethasone may not be strong, even at high doses: insights from a case of tacrolimus co-administration. Journal of Pharmaceutical Health Care and Sciences 9:1.
Crossref
Adrian Hall, Hugues Chanteux, Karelle MénochetMarie Ledecq & Monika-Sarah E. D. Schulze. (2021) Designing Out PXR Activity on Drug Discovery Projects: A Review of Structure-Based Methods, Empirical and Computational Approaches. Journal of Medicinal Chemistry 64:10, pages 6413-6522.
Crossref
Donna A Volpe & Praveen V Balimane. (2018) Application of in vitro CYP and transporter assays to predict clinical drug–drug interactions . Bioanalysis 10:9, pages 619-623.
Crossref
Beth Williamson, Mathias Lorbeer, Michael D. Mitchell, Timothy G. Brayman & Robert J. Riley. (2016) Evaluation of a novel PXR-knockout in HepaRG ™ cells . Pharmacology Research & Perspectives 4:5, pages e00264.
Crossref
Piyanuch Wonganan, Kristina Jonsson-Schmunk, Shellie M. Callahan, Jin Huk Choi & Maria A. Croyle. (2014) Evaluation of the HC-04 Cell Line as an In Vitro Model for Mechanistic Assessment of Changes in Hepatic Cytochrome P450 3A during Adenovirus Infection. Drug Metabolism and Disposition 42:7, pages 1191-1201.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.