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Dipeptidyl peptidase-IV and related molecules: markers of malignancy?

, MD PhD (Professor, University Teacher, Scientist) , , MSc (University Teacher, PhD Student) , , MD (University Teacher, PhD Student) & , PhD (University Teacher, Scientist)
Pages 677-689 | Published online: 04 Jun 2008

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Hidayat Hussain, Ghulam Abbas, Ivan R. Green & Iftikhar Ali. (2019) Dipeptidyl peptidase IV inhibitors as a potential target for diabetes: patent review (2015-2018). Expert Opinion on Therapeutic Patents 29:7, pages 535-553.
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Articles from other publishers (21)

Petr Busek, Jonathan S. Duke-Cohan & Aleksi Sedo. (2022) Does DPP-IV Inhibition Offer New Avenues for Therapeutic Intervention in Malignant Disease?. Cancers 14:9, pages 2072.
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Gustavo A. Arias-Pinilla, Angus G. Dalgleish, Satvinder Mudan, Izhar Bagwan, Anthony J. Walker & Helmout Modjtahedi. (2020) Development and application of two novel monoclonal antibodies against overexpressed CD26 and integrin α3 in human pancreatic cancer. Scientific Reports 10:1.
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Njanja Enz, Gwendolyn Vliegen, Ingrid De Meester & Wolfgang Jungraithmayr. (2019) CD26/DPP4 - a potential biomarker and target for cancer therapy. Pharmacology & Therapeutics 198, pages 135-159.
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P. B. Deshpande & S. R. Butle. (2018) Determination of Dipeptidyl Peptidase-4 Inhibitors by Spectrophotometric and Chromatographic Methods. Journal of Analytical Chemistry 73:4, pages 303-316.
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Zeynab Aliyari Serej, Abbas Ebrahimi Kalan, Ahmad Mehdipour & Hojjatollah Nozad Charoudeh. (2017) Regulation and roles of CD26/DPPIV in hematopoiesis and diseases. Biomedicine & Pharmacotherapy 91, pages 88-94.
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Petr Busek, Zdislava Vanickova, Petr Hrabal, Marek Brabec, Premysl Fric, Miroslav Zavoral, Jan Skrha, Klara Kmochova, Martin Laclav, Bohus Bunganic, Koen Augustyns, Pieter Van Der Veken & Aleksi Sedo. (2016) Increased tissue and circulating levels of dipeptidyl peptidase-IV enzymatic activity in patients with pancreatic ductal adenocarcinoma. Pancreatology 16:5, pages 829-838.
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Susumu Saigusa, Yuji Toiyama, Koji Tanaka, Yasuhiro Inoue, Koichiro Mori, Shozo Ide, Hiroki Imaoka, Mikio Kawamura, Yasuhiko Mohri & Masato Kusunoki. (2015) Prognostic relevance of stromal CD26 expression in rectal cancer after chemoradiotherapy. International Journal of Clinical Oncology 21:2, pages 350-358.
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Bing Zheng, Jun Liu, Jianlei Gu, Yao Lu, Wei Zhang, Min Li & Hui Lu. (2015) A three-gene panel that distinguishes benign from malignant thyroid nodules. International Journal of Cancer 136:7, pages 1646-1654.
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Jixin Zhong, Quan Gong, Aditya Goud, Srividya Srinivasamaharaj & Sanjay Rajagopalan. (2015) Recent Advances in Dipeptidyl-Peptidase-4 Inhibition Therapy: Lessons from the Bench and Clinical Trials. Journal of Diabetes Research 2015, pages 1-14.
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Arpi Nazarian, Kevin Lawlor, San San Yi, John Philip, Mousumi Ghosh, Mariana Yaneva, Josep Villanueva, Alan Saghatelian, Melissa Assel, Andrew J. Vickers, James A. Eastham, Howard I. Scher, Brett S. Carver, Hans Lilja & Paul Tempst. (2014) Inhibition of Circulating Dipeptidyl Peptidase 4 Activity in Patients with Metastatic Prostate Cancer. Molecular & Cellular Proteomics 13:11, pages 3082-3096.
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Zhendi Wang, Christina Grigo, Julia Steinbeck, Stephan von Hörsten, Kerstin Amann & Christoph Daniel. (2014) Soluble DPP4 originates in part from bone marrow cells and not from the kidney. Peptides 57, pages 109-117.
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Colin Siu-Chi Lam, Alvin Ho-Kwan Cheung, Sunny Kit-Man Wong, Timothy Ming-Hun Wan, Lui Ng, Ariel Ka-Man Chow, Nathan Shiu-Man Cheng, Ryan Chung-Hei Pak, Hung-Sing Li, Johnny Hon-Wai Man, Thomas Chung-Cheung Yau, Oswens Siu-Hung Lo, Jensen Tung-Chung Poon, Roberta Wen-Chi Pang & Wai Lun Law. (2014) Prognostic Significance of CD26 in Patients with Colorectal Cancer. PLoS ONE 9:5, pages e98582.
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Shi Sen, Yanzheng He, Daisuke Koya & Keizo Kanasaki. (2014) Cancer biology in diabetes. Journal of Diabetes Investigation 5:3, pages 251-264.
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Bhumika D. Patel & Manjunath D. Ghate. (2014) Recent approaches to medicinal chemistry and therapeutic potential of dipeptidyl peptidase-4 (DPP-4) inhibitors. European Journal of Medicinal Chemistry 74, pages 574-605.
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Nuria Sánchez-Otero, Francisco Javier Rodríguez-Berrocal, María Páez de la Cadena, María Isabel Botana-Rial & Oscar J. Cordero. (2014) Evaluation of pleural effusion sCD26 and DPP-IV as diagnostic biomarkers in lung disease. Scientific Reports 4:1.
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Pamela A Havre, Long H Dang, Kei Ohnuma, Satoshi Iwata, Chikao Morimoto & Nam H Dang. (2013) CD26 Expression on T-Anaplastic Large Cell Lymphoma (ALCL) Line Karpas 299 is associated with increased expression of Versican and MT1-MMP and enhanced adhesion. BMC Cancer 13:1.
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Petr Busek, Jarmila Stremenova, Lucie Sromova, Marek Hilser, Eva Balaziova, Dalibor Kosek, Jana Trylcova, Hynek Strnad, Evzen Krepela & Aleksi Sedo. (2012) Dipeptidyl peptidase-IV inhibits glioma cell growth independent of its enzymatic activity. The International Journal of Biochemistry & Cell Biology 44:5, pages 738-747.
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Aleksandra Erić-Nikolić, Ivana Z. Matić, Milica Ðorđević, Zorka Milovanović, Ivan Marković, Radan Džodić, Momčilo Inić, Tatjana Srdić-Rajić, Marko Jevrić, Dušica Gavrilović, Oscar J. Cordero & Zorica D. Juranić. (2011) Serum DPPIV activity and CD26 expression on lymphocytes in patients with benign or malignant breast tumors. Immunobiology 216:8, pages 942-946.
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Lucie Sromova, Helena Mareckova, Liliana Sedova, Eva Balaziova & Aleksi Sedo. (2010) Dipeptidyl peptidase-IV in synovial fluid and in synovial fluid mononuclear cells of patients with rheumatoid arthritis. Clinica Chimica Acta 411:15-16, pages 1046-1050.
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Tomas Stulc & Aleksi Sedo. (2010) Inhibition of multifunctional dipeptidyl peptidase-IV: Is there a risk of oncological and immunological adverse effects?. Diabetes Research and Clinical Practice 88:2, pages 125-131.
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Oscar J. Cordero, Francisco J. Salgado & Montserrat Nogueira. (2009) On the origin of serum CD26 and its altered concentration in cancer patients. Cancer Immunology, Immunotherapy 58:11, pages 1723-1747.
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