Advanced search
Publication Cover
Expert Opinion on Medical Diagnostics Volume 7, 2013 - Issue 4
Journal homepage
168
Views
26
CrossRef citations to date
0
Altmetric
Reviews

Molecular biomarkers in cervical cancer diagnosis: a critical appraisal

Rogier JNTM LitjensMaastricht University Medical Centre, GROW-School for Oncology and Developmental Biology, Department of Obstetrics and Gynaecology, PO Box 616, 6200MD Maastricht, The Netherlands+31 43 3874767; +31 43 3874765; [email protected];Maastricht University Medical Centre, GROW-School for Oncology and Developmental Biology, Department of Molecular Cell Biology, PO Box 5800, 6202AZ Maastricht, The Netherlands
, MD,
Anton HN HopmanMaastricht University Medical Centre, GROW-School for Oncology and Developmental Biology, Department of Molecular Cell Biology, PO Box 5800, 6202AZ Maastricht, The Netherlands
, PhD,
Koen K van de VijverMaastricht University Medical Centre, GROW-School for Oncology and Developmental Biology, Department of Pathology, PO Box 5800, 6202AZ Maastricht, The Netherlands
, MD PhD,
Frans CS RamaekersMaastricht University Medical Centre, GROW-School for Oncology and Developmental Biology, Department of Molecular Cell Biology, PO Box 5800, 6202AZ Maastricht, The Netherlands
, PhD,
Roy FPM KruitwagenMaastricht University Medical Centre, GROW-School for Oncology and Developmental Biology, Department of Obstetrics and Gynaecology, PO Box 616, 6200MD Maastricht, The Netherlands+31 43 3874767; +31 43 3874765; [email protected]
, MD PhD &
Arnold-Jan KruseMaastricht University Medical Centre, GROW-School for Oncology and Developmental Biology, Department of Obstetrics and Gynaecology, PO Box 616, 6200MD Maastricht, The Netherlands+31 43 3874767; +31 43 3874765; [email protected]
, MD PhD
Pages 365-377 | Published online: 19 Jun 2013

Citations (26)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Wei Wang, Xin Xie, Zhangjian Zhou & Hao Zhang. (2021) Expression Analysis of MIST1 and EMT Markers in Primary Tumor Samples Points to MIST1 as a Biomarker of Cervical Cancer. International Journal of General Medicine 14, pages 1293-1300.
Read now
Mariano A Molina, Ludovica Carosi Diatricch, Marina Castany Quintana, Willem JG Melchers & Karolina M Andralojc. (2020) Cervical cancer risk profiling: molecular biomarkers predicting the outcome of hrHPV infection. Expert Review of Molecular Diagnostics 20:11, pages 1099-1120.
Read now
Margot M Koeneman, Roy FPM Kruitwagen, Hans W Nijman, Brigitte FM Slangen, Toon Van Gorp & Arnold-Jan Kruse. (2015) Natural history of high-grade cervical intraepithelial neoplasia: a review of prognostic biomarkers. Expert Review of Molecular Diagnostics 15:4, pages 527-546.
Read now

Articles from other publishers (23)

Bilal Ahmad Mir, Arif Ahmad, Nighat Farooq, M. Vishnu Priya, A. H. Siddiqui, M. Asif, Rouquia Manzoor, Hassan Mubarak Ishqi, Suliman Y. Alomar & P. F. Rahaman. (2023) Increased expression of HPV-E7 oncoprotein correlates with a reduced level of pRb proteins via high viral load in cervical cancer. Scientific Reports 13:1.
Crossref
Kirthana Sharma, Dorothy A Machalek, Zheng Q Toh, Demisew Amenu, Mazvita Muchengeti, Andrew K Ndlovu, Alex Mremi, Bariki Mchome, Andrew J Vallely, Lynette Denny, Helen Rees & Suzanne M Garland. (2023) No woman left behind: achieving cervical cancer elimination among women living with HIV. The Lancet HIV 10:6, pages e412-e420.
Crossref
Johanna Herbst, Klaus Pantel, Katharina Effenberger & Harriet Wikman. (2022) Clinical applications and utility of cell-free DNA-based liquid biopsy analyses in cervical cancer and its precursor lesions. British Journal of Cancer 127:8, pages 1403-1410.
Crossref
Ena Pešut, Anamaria Đukić, Lucija Lulić, Josipa Skelin, Ivana Šimić, Nina Milutin Gašperov, Vjekoslav Tomaić, Ivan Sabol & Magdalena Grce. (2021) Human Papillomaviruses-Associated Cancers: An Update of Current Knowledge. Viruses 13:11, pages 2234.
Crossref
Siriporn Keeratichamroen, Pantipa Subhasitanont, Daranee Chokchaichamnankit, Churat Weeraphan, Kittirat Saharat, Narongrit Sritana, Nuttavut Kantathavorn, Kriangpol Wiriyaukaradecha, Thaniya Sricharunrat, N. Monique Paricharttanakul, Chirayu Auewarakul, Jisnuson Svasti & Chantragan Srisomsap. (2020) Identification of potential cervical cancer serum biomarkers in Thai patients. Oncology Letters.
Crossref
Xiaoqun Ma, Thangavel Lakshmipriya & Subash C. B. Gopinath. (2019) Recent Advances in Identifying Biomarkers and High-Affinity Aptamers for Gynecologic Cancers Diagnosis and Therapy. Journal of Analytical Methods in Chemistry 2019, pages 1-9.
Crossref
Sundara Raj Sreeja, Hyun Yi Lee, Minji Kwon, Nitin Shivappa, James R. Hebert & Mi Kyung Kim. (2019) Dietary Inflammatory Index and Its Relationship with Cervical Carcinogenesis Risk in Korean Women: A Case-Control Study. Cancers 11:8, pages 1108.
Crossref
Margot M Koeneman, Irene T Ovestad, Emiel A. M. Janssen, Monique Ummelen, Roy F. P. M. Kruitwagen, Anton H. Hopman & Arnold J. Kruse. (2018) Gain of Chromosomal Region 3q26 as a Prognostic Biomarker for High-Grade Cervical Intraepithelial Neoplasia: Literature Overview and Pilot Study. Pathology & Oncology Research 25:2, pages 549-557.
Crossref
Marette H. Lee, Sarah J. Finlayson, Ksenia Gukova, Gillian Hanley, Dianne Miller & Leslie Ann Sadownik. (2018) Outcomes of Conservative Management of High Grade Squamous Intraepithelial Lesions in Young Women. Journal of Lower Genital Tract Disease 22:3, pages 212-218.
Crossref
Lu-Lu Sun, Yuan Liu, Xiao Sun, Lei Pan, Dan Wu & Yu-Dong Wang. (2018) Limited Role of Promoter Methylation of MGMT and C13ORF18 in Triage of Low-Grade Squamous Intraepithelial Lesion. Chinese Medical Journal 131:8, pages 939-944.
Crossref
Yingji Jin, Seung Cheol Kim, Hyoung Jin Kim, Woong Ju, Yun Hwan Kim & Hong-Jin Kim. (2018) Use of protein-based biomarkers of exfoliated cervical cells for primary screening of cervical cancer. Archives of Pharmacal Research 41:4, pages 438-449.
Crossref
Peter A van Dam, Christian Rolfo, Rossana Ruiz, Patrick Pauwels, Christophe Van Berckelaer, XuanBich Trinh, Jose Ferri Gandia, Johannes P. Bogers & Steven Van Laere. (2018) Potential new biomarkers for squamous carcinoma of the uterine cervix. ESMO Open 3:4, pages e000352.
Crossref
Yingji Jin, Seung Cheol Kim, Hyoung Jin Kim, Woong Ju, Yun Hwan Kim & Hong-Jin Kim. (2017) Use of autoantibodies against tumor-associated antigens as serum biomarkers for primary screening of cervical cancer. Oncotarget 8:62, pages 105425-105439.
Crossref
Akash M. Mehta, Merel Mooij, Ivan Brankovi?, Sander Ouburg, Servaas A. Morr? & Ekaterina S. Jordanova. (2017) Cervical Carcinogenesis and Immune Response Gene Polymorphisms: A Review. Journal of Immunology Research 2017, pages 1-12.
Crossref
V?nia Sammartino Mariano, Adriana Tarl? Lorenzi, Cristovam Scapulatempo-Neto, Ma?ra Degiovani Stein, Julio Cesar Possati Resende, M?rcio Antoniazzi, Luisa Lina Villa, Jos? Eduardo Levi, Adhemar Longatto-Filho & Jos? Humberto Tavares Guerreiro Fregnani. (2016) A Low-Cost HPV Immunochromatographic Assay to Detect High-Grade Cervical Intraepithelial Neoplasia. PLOS ONE 11:10, pages e0164892.
Crossref
Neil Ari Wijetunga, Miriam Ben-Dayan, Jessica Tozour, Robert D. Burk, Nicolas F. Schlecht, Mark H. Einstein & John M. Greally. (2016) A polycomb-mediated epigenetic field defect precedes invasive cervical carcinoma. Oncotarget 7:38, pages 62133-62143.
Crossref
N. Ari Wijetunga, Thomas J. Belbin, Robert D. Burk, Kathleen Whitney, Maria Abadi, John M. Greally, Mark H. Einstein & Nicolas F. Schlecht. (2016) Novel epigenetic changes in CDKN2A are associated with progression of cervical intraepithelial neoplasia. Gynecologic Oncology 142:3, pages 566-573.
Crossref
Harib Ezaldein, Jason P. Lott, Jennifer M. McNiff, Pei Hui, Natalia Buza & Christine J. Ko. (2015) Grading of atypia in genital skin lesions: routine microscopic evaluation and use of p16 immunostaining. Journal of Cutaneous Pathology 42:8, pages 519-526.
Crossref
Heather Griffin, Yasmina Soneji, Romy Van Baars, Rupali Arora, David Jenkins, Miekel van de Sandt, Zhonglin Wu, Wim Quint, Robert Jach, Krzysztof Okon, Hubert Huras, Albert Singer & John Doorbar. (2015) Stratification of HPV-induced cervical pathology using the virally encoded molecular marker E4 in combination with p16 or MCM. Modern Pathology 28:7, pages 977-993.
Crossref
Kai‐Hung Wang, Cuei‐Jyuan Lin, Chou‐Jen Liu, Dai‐Wei Liu, Rui‐Lan Huang, Dah‐Ching Ding, Ching‐Feng Weng & Tang‐Yuan Chu. (2014) Global methylation silencing of clustered proto‐cadherin genes in cervical cancer: serving as diagnostic markers comparable to HPV . Cancer Medicine 4:1, pages 43-55.
Crossref
Erika R. Matheus, Marco A. Zonta, Michelle G. Discacciati, Priscila Paruci, Fernanda Velame, Laura B.S. Cardeal, Silvia B.M. Barros, Antonio C. Pignatari & Silvya S. Maria-Engler. (2014) MMP-9 expression increases according to the grade of squamous intraepithelial lesion in cervical smears. Diagnostic Cytopathology 42:10, pages 827-833.
Crossref
L.N. Calil, M.I.A. Edelweiss, L. Meurer, C.N. Igansi & M.C. Bozzetti. (2014) p16INK4a and Ki67 expression in normal, dysplastic and neoplastic uterine cervical epithelium and human papillomavirus (HPV) infection. Pathology - Research and Practice 210:8, pages 482-487.
Crossref
George Valasoulis, Sofia-Melina Stasinou, Maria Nasioutziki, Antonis Athanasiou, Maria Zografou, Aris Spathis, Aristotelis Loufopoulos, Petros Karakitsos, Evangelos Paraskevaidis & Maria Kyrgiou. (2014) Expression of HPV-related biomarkers and grade of cervical intraepithelial lesion at treatment. Acta Obstetricia et Gynecologica Scandinavica 93:2, pages 194-200.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.