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Expert Opinion on Orphan Drugs Volume 1, 2013 - Issue 1
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Drug Evaluations

The erythropoietin analog ARA 290 for treatment of sarcoidosis-induced chronic neuropathic pain

Marieke NiestersLeiden University Medical Center, Department of Anesthesiology, 2300 RC Leiden, The Netherlands
,
Maarten SwartjesLeiden University Medical Center, Department of Anesthesiology, 2300 RC Leiden, The Netherlands
,
Lara HeijLeiden University Medical Center, Department of Anesthesiology, 2300 RC Leiden, The Netherlands
,
Michael BrinesAraim Pharmaceuticals, Inc., Ossining, NY 10562, USA
,
Anthony CeramiLeiden University Medical Center, Department of Anesthesiology, 2300 RC Leiden, The Netherlands;Araim Pharmaceuticals, Inc., Ossining, NY 10562, USA
,
Ann DunneAraim Pharmaceuticals, Inc., Ossining, NY 10562, USA
,
Elske HoitsmaDepartment of Neurology, Diaconessenhuis, 2334 CK Leiden, The Netherlands+31 71 526 2301; [email protected]
&
Albert DahanLeiden University Medical Center, Department of Anesthesiology, 2300 RC Leiden, The Netherlands
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Pages 77-87 | Published online: 17 Dec 2012

Citations (9)

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Read on this site (2)

Monique van Velzen, Lara Heij, Marieke Niesters, Anthony Cerami, Ann Dunne, Albert Dahan & Michael Brines. (2014) ARA 290 for treatment of small fiber neuropathy in sarcoidosis. Expert Opinion on Investigational Drugs 23:4, pages 541-550.
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Sabina Antoniu. (2014) Fresh from the designation pipeline: orphan drugs recently designated in the European Union (September – November 2013). Expert Opinion on Orphan Drugs 2:3, pages 311-315.
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Articles from other publishers (7)

Nolan M. Winicki, Alay P. Nanavati, Christopher H. Morrell, Jack M. Moen, Jessie E. Axsom, Melissa Krawczyk, Natalia N. Petrashevskaya, Max G. Beyman, Christopher Ramirez, Irene Alfaras, Sarah J. Mitchell, Magdalena Juhaszova, Daniel R. Riordon, Mingyi Wang, Jing Zhang, Anthony Cerami, Michael Brines, Steven J. Sollott, Rafael de Cabo & Edward G. Lakatta. (2023) A small erythropoietin derived non-hematopoietic peptide reduces cardiac inflammation, attenuates age associated declines in heart function and prolongs healthspan. Frontiers in Cardiovascular Medicine 9.
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Inês Silva, Carolina Alípio, Rui Pinto & Vanessa Mateus. (2021) Potential anti-inflammatory effect of erythropoietin in non-clinical studies in vivo: A systematic review. Biomedicine & Pharmacotherapy 139, pages 111558.
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Noemi Lois, Evie Gardner, Margaret McFarland, David Armstrong, Christine McNally, Nuala Jane Lavery, Christina Campbell, Rita I Kirk, Daiva Bajorunas, Ann Dunne, Anthony Cerami & Michael Brines. (2020) A Phase 2 Clinical Trial on the Use of Cibinetide for the Treatment of Diabetic Macular Edema. Journal of Clinical Medicine 9:7, pages 2225.
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Karen S. Cheung Tung Shing, Sophie E. Broughton, Tracy L. Nero, Kevin Gillinder, Melissa D. Ilsley, Hayley Ramshaw, Angel F. Lopez, Michael D. W. Griffin, Michael W. Parker, Andrew C. Perkins & Urmi Dhagat. (2018) EPO does not promote interaction between the erythropoietin and beta-common receptors. Scientific Reports 8:1.
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Albert Dahan, Michael Brines, Marieke Niesters, Anthony Cerami & Monique van Velzen. (2016) Targeting the innate repair receptor to treat neuropathy. PAIN Reports 1:1, pages e566.
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Massimo Collino, Christoph Thiemermann, Anthony Cerami & Michael Brines. (2015) Flipping the molecular switch for innate protection and repair of tissues: Long-lasting effects of a non-erythropoietic small peptide engineered from erythropoietin. Pharmacology & Therapeutics 151, pages 32-40.
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Albert Dahan, Ann Dunne, Maarten Swartjes, Paolo L. Proto, Lara Heij, Oscar Vogels, Monique van Velzen, Elise Sarton, Marieke Niesters, Martijn R. Tannemaat, Anthony Cerami & Michael Brines. (2013) ARA 290 Improves Symptoms in Patients with Sarcoidosis-Associated Small Nerve Fiber Loss and Increases Corneal Nerve Fiber Density. Molecular Medicine 19:1, pages 334-345.
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