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Expert Review of Anticancer Therapy Volume 13, 2013 - Issue 7
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Review

The role of necroptosis, an alternative form of cell death, in cancer therapy

Xinfang Yu Cancer Research Institute, Xiangya School of Medicine, Central South University, 110 Xiang Ya Road, Changsha 410078, Hunan, China; Cancer Research Institute, Xiangya School of Medicine, Central South University, 110 Xiang Ya Road, Changsha 410078, Hunan, China
,
Qipan Deng Cancer Research Institute, Xiangya School of Medicine, Central South University, 110 Xiang Ya Road, Changsha 410078, Hunan, China; The Hormel Institute, University of Minnesota, 801 16th Avenue NE, Austin, MN 55912, USA
,
Ann M Bode The Hormel Institute, University of Minnesota, 801 16th Avenue NE, Austin, MN 55912, USA; The Hormel Institute, University of Minnesota, 801 16th Avenue NE, Austin, MN 55912, USA
,
Zigang Dong The Hormel Institute, University of Minnesota, 801 16th Avenue NE, Austin, MN 55912, USA; The Hormel Institute, University of Minnesota, 801 16th Avenue NE, Austin, MN 55912, USA
&
Ya Cao Cancer Research Institute, Xiangya School of Medicine, Central South University, 110 Xiang Ya Road, Changsha 410078, Hunan, China. [email protected]; Molecular Imaging Center, Central South University, 110 Xiang Ya Road, Changsha 410078, Hunan, China; Cancer Research Institute, Xiangya School of Medicine, Central South University, 110 Xiang Ya Road, Changsha 410078, Hunan, China. [email protected]; Molecular Imaging Center, Central South University, 110 Xiang Ya Road, Changsha 410078, Hunan, China
Pages 883-893 | Published online: 10 Jan 2014

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Lu Chen, Meng Qi, Linlin Zhang, Fuchang Yu, Dayong Tao, Chunyan Xu & Shiwen Xu. (2023) Di(2‐ethylhexyl) phthalate and microplastics cause necroptosis and apoptosis in hepatocytes of mice by inducing oxidative stress. Environmental Toxicology 38:6, pages 1226-1238.
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Keng Ye, Zhimin Chen & Yanfang Xu. (2023) The double-edged functions of necroptosis. Cell Death & Disease 14:2.
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Yue Zhang, Yuting Lu, Peijun Zhang, Xinchi Shang & Yuehong Li. (2022) Brain Injury Induced by Mercury in Common Carp: Novel Insight from Transcriptome Analysis. Biological Trace Element Research 201:1, pages 403-411.
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Guo Li, Zhijie Xu, Jinwu Peng, Yuanliang Yan, Yong Liu, Xin Zhang, Yuanzheng Qiu & Chencheng Fu. (2022) The RIPK family: expression profile and prognostic value in lung adenocarcinoma. Aging 14:14, pages 5946-5958.
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Samantha Sarcognato, Iris E. M. de Jong, Luca Fabris, Massimiliano Cadamuro & Maria Guido. (2020) Necroptosis in Cholangiocarcinoma. Cells 9:4, pages 982.
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Jiabin Zhou, Genhua Li, Guangkui Han, Song Feng, Yuhan Liu, Jun Chen, Chen Liu, Lei Zhao & Feng Jin. (2019) Emodin induced necroptosis in the glioma cell line U251 via the TNF-α/RIP1/RIP3 pathway. Investigational New Drugs 38:1, pages 50-59.
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Jasdeep Mann, Ning Yang, Rachel Montpetit, Raven Kirschenman, Hélène Lemieux & Ing Swie Goping. (2020) BAD sensitizes breast cancer cells to docetaxel with increased mitotic arrest and necroptosis. Scientific Reports 10:1.
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José Tarcísio de Giffoni de Carvalho, Débora da Silva Baldivia, Daniel Ferreira Leite, Laura Costa Alves de Araújo, Priscilla Pereira de Toledo Espindola, Katia Avila Antunes, Paola Santos Rocha, Kely de Picoli Souza & Edson Lucas dos Santos. (2019) Medicinal Plants from Brazilian Cerrado: Antioxidant and Anticancer Potential and Protection against Chemotherapy Toxicity. Oxidative Medicine and Cellular Longevity 2019, pages 1-16.
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Long‐long Xie, Feng Shi, Zheqiong Tan, Yueshuo Li, Ann M. Bode & Ya Cao. (2018) Mitochondrial network structure homeostasis and cell death. Cancer Science 109:12, pages 3686-3694.
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Ayaz Najafov, Ioannis K. Zervantonakis, Adnan K. Mookhtiar, Patricia Greninger, Ryan J. March, Regina K. Egan, Hoang Son Luu, Daniel G. Stover, Ursula A. Matulonis, Cyril H. Benes & Junying Yuan. (2018) BRAF and AXL oncogenes drive RIPK3 expression loss in cancer. PLOS Biology 16:8, pages e2005756.
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Seon Woo, Seung Seo, Kyoung-jin Min, Seung-Soon Im, Ju-Ock Nam, Jong-Soo Chang, Shin Kim, Jong-Wook Park & Taeg Kwon. (2018) Corosolic Acid Induces Non-Apoptotic Cell Death through Generation of Lipid Reactive Oxygen Species Production in Human Renal Carcinoma Caki Cells. International Journal of Molecular Sciences 19:5, pages 1309.
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J.C. Davila, S. Levin & Z.A. Radi. 2018. Comprehensive Toxicology. Comprehensive Toxicology 404 453 .
Seon Min Woo & Taeg Kyu Kwon. (2017) Novel non-apoptotic cell death: ferroptosis. Yeungnam University Journal of Medicine 34:2, pages 174-181.
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Weijie Liang, Meiji Chen, Dongdan Zheng, Jieyi He, Mingcai Song, Liqiu Mo, Jianqiang Feng & Jun Lan. (2017) A novel damage mechanism: Contribution of the interaction between necroptosis and ROS to high glucose-induced injury and inflammation in H9c2 cardiac cells. International Journal of Molecular Medicine 40:1, pages 201-208.
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Deepika Arora, Pradeep Kumar Sharma, Mohammed Haris Siddiqui & Yogeshwer Shukla. (2017) Necroptosis: Modules and molecular switches with therapeutic implications. Biochimie 137, pages 35-45.
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Arthur ZimmermannArthur Zimmermann. 2017. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract 3263 3270 .
Anna L. Greenshields, Trevor G. Shepherd & David W. Hoskin. (2017) Contribution of reactive oxygen species to ovarian cancer cell growth arrest and killing by the anti-malarial drug artesunate. Molecular Carcinogenesis 56:1, pages 75-93.
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Mao-Bin Meng, Huan-Huan Wang, Yao-Li Cui, Zhi-Qiang Wu, Yang-Yang Shi, Nicholas G. Zaorsky, Lei Deng, Zhi-Yong Yuan, You Lu & Ping Wang. (2016) Necroptosis in tumorigenesis, activation of anti-tumor immunity, and cancer therapy. Oncotarget 7:35, pages 57391-57413.
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Yan Diao, Xiaobin Ma, WeiLi Min, Shuai Lin, HuaFeng Kang, ZhiJun Dai, Xijing Wang & Yang Zhao. (2016) Dasatinib promotes paclitaxel-induced necroptosis in lung adenocarcinoma with phosphorylated caspase-8 by c-Src. Cancer Letters 379:1, pages 12-23.
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Shengfu Piao & Ravi K. Amaravadi. (2016) Targeting the lysosome in cancer. Annals of the New York Academy of Sciences 1371:1, pages 45-54.
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Arthur ZimmermannArthur Zimmermann. 2016. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract 1 8 .
George A. Alexiou, Konstantinos I. Tsamis & Athanasios P. Kyritsis. (2015) Targeting Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (TRAIL): A Promising Therapeutic Strategy in Gliomas. Seminars in Pediatric Neurology 22:1, pages 35-39.
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Xinfang Yu, Qipan Deng, Wei Li, Lanbo Xiao, Xiangjian Luo, Xiaolan Liu, Lifang Yang, Songling Peng, Zhihui Ding, Tao Feng, Jian Zhou, Jia Fan, Ann M. Bode, Zigang Dong, Jikai Liu & Ya Cao. (2014) Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNFα and ROS production. Oncotarget 6:4, pages 1995-2008.
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Alexey V. Zamaraev, Gelina S. Kopeina, Boris Zhivotovsky & Inna N. Lavrik. (2014) Cell death controlling complexes and their potential therapeutic role. Cellular and Molecular Life Sciences 72:3, pages 505-517.
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Yue Li, Ying Wang, Suihai Wang, Yanjun Gao, Xuefeng Zhang & Chunhua Lu. (2014) Oridonin phosphate-induced autophagy effectively enhances cell apoptosis of human breast cancer cells. Medical Oncology 32:1.
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JUN SOO PARK, WAN TAE KIM, SHIN KIM, TAEG KYU KWON, BYEONG-CHURL JANG, EUNG-SEOK LEE & JONG WOOK PARK. (2014) FPDHP, a novel anticancer agent, induces cell detachment and caspase-dependent apoptosis in Caki cells. International Journal of Molecular Medicine 34:4, pages 1051-1056.
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