Advanced search
Publication Cover
Expert Review of Molecular Diagnostics Volume 15, 2015 - Issue 9
Submit an article Journal homepage
865
Views
21
CrossRef citations to date
0
Altmetric
Review

What was old is new again: using the host response to diagnose infectious disease

Emily R KoDepartment of Medicine Center for Applied Genomics & Precision Medicine, Duke University, Durham, NC 27708, USA;Department of Medicine, Duke University Duke Regional Hospital, Durham, NC 27710, USA
,
William E YangDuke University School of Medicine, Duke University, Durham, NC 27710, USA
,
Micah T McClainDepartment of Medicine Center for Applied Genomics & Precision Medicine, Duke University, Durham, NC 27708, USA;Department of Medicine, Division of Infectious Diseases & International Health, Duke University, Durham, NC 27710, USA;Section for Infectious Diseases, Medicine Service, Durham Veteran’s Affairs Medical Center, Durham, NC 27705, USA
,
Christopher W WoodsDepartment of Medicine Center for Applied Genomics & Precision Medicine, Duke University, Durham, NC 27708, USA;Department of Medicine, Division of Infectious Diseases & International Health, Duke University, Durham, NC 27710, USA;Section for Infectious Diseases, Medicine Service, Durham Veteran’s Affairs Medical Center, Durham, NC 27705, USACorrespondence[email protected] [email protected]
,
Geoffrey S GinsburgDepartment of Medicine Center for Applied Genomics & Precision Medicine, Duke University, Durham, NC 27708, USACorrespondence[email protected] [email protected]
&
Ephraim L TsalikDepartment of Medicine Center for Applied Genomics & Precision Medicine, Duke University, Durham, NC 27708, USA;Department of Medicine, Division of Infectious Diseases & International Health, Duke University, Durham, NC 27710, USA;Emergency Medicine Service, Durham Veteran’s Affairs Medical Center, Durham, NC 27705, USACorrespondence[email protected] [email protected]
Pages 1143-1158 | Published online: 04 Jul 2015

Citations (21)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Karen E. Kempsell, Graham Ball & Tamas Szakmany. (2016) Issues in biomarker identification, validation and development for disease diagnostics in Public Health. Expert Review of Molecular Diagnostics 16:4, pages 383-386.
Read now

Articles from other publishers (20)

Kennedy T.L. Gifford & Brett E. Pickett. (2022) Comparative meta-analysis of host transcriptional response during Streptococcus pneumoniae carriage or infection. Microbial Pathogenesis 173, pages 105816.
Crossref
Sameh S. M. Soliman, Eman M. El-Labbad, Ameera Abu-Qiyas, Bahgat Fayed, Alshaimaa M. Hamoda, Ahmed M. Al-Rawi, Salam Dakalbab, Abdel-Nasser A. El-Shorbagi, Mawieh Hamad, Ashraf S. Ibrahim & Mohammad G. Mohammad. (2022) Novel Secreted Peptides From Rhizopus arrhizus var. delemar With Immunomodulatory Effects That Enhance Fungal Pathogenesis. Frontiers in Microbiology 13.
Crossref
Hayoung Lee & Seung Il Kim. (2022) Review of Liquid Chromatography-Mass Spectrometry-Based Proteomic Analyses of Body Fluids to Diagnose Infectious Diseases. International Journal of Molecular Sciences 23:4, pages 2187.
Crossref
Thyago Leal-Calvo, Charlotte Avanzi, Mayara Abud Mendes, Andrej Benjak, Philippe Busso, Roberta Olmo Pinheiro, Euzenir Nunes Sarno, Stewart Thomas Cole & Milton Ozório Moraes. (2021) A new paradigm for leprosy diagnosis based on host gene expression. PLOS Pathogens 17:10, pages e1009972.
Crossref
Pedro Mendes de Azambuja Rodrigues, Richard Hemmi Valente, Giselle Villa Flor Brunoro, Helder Takashi Imoto Nakaya, Mariana Araújo-Pereira, Patricia Torres Bozza, Fernando Augusto Bozza & Monique Ramos de Oliveira Trugilho. (2021) Proteomics reveals disturbances in the immune response and energy metabolism of monocytes from patients with septic shock. Scientific Reports 11:1.
Crossref
Jianchao Ying, Qian Wang, Teng Xu & Zhongqiu Lu. (2021) Diagnostic potential of a gradient boosting-based model for detecting pediatric sepsis. Genomics 113:1, pages 874-883.
Crossref
Suprabhat Mukherjee & Niladri Mukherjee. 2021. Modern Techniques in Biosensors. Modern Techniques in Biosensors 1 36 .
Giovanni Del Borrello, Matteo Stocchero, Giuseppe Giordano, Paola Pirillo, Stefania Zanconato, Liviana Da Dalt, Silvia Carraro, Susanna Esposito & Eugenio Baraldi. (2019) New insights into pediatric community‐acquired pneumonia gained from untargeted metabolomics: A preliminary study. Pediatric Pulmonology 55:2, pages 418-425.
Crossref
Steven E. Schutzer. 2020. Microbial Forensics. Microbial Forensics 207 223 .
Michael D. Ward, Ernst E. Brueggemann, Tara Kenny, Raven E. Reitstetter, Christopher R. Mahone, Sylvia Trevino, Kelly Wetzel, Ginger C. Donnelly, Cary Retterer, Robert B. NorgrenJr.Jr., Rekha G. Panchal, Travis K. Warren, Sina Bavari & Lisa H. Cazares. (2019) Characterization of the plasma proteome of nonhuman primates during Ebola virus disease or melioidosis: a host response comparison. Clinical Proteomics 16:1.
Crossref
Qian Wang, Teng Xu, Yu Tong, Jianbo Wu, Weijian Zhu, Zhongqiu Lu & Jianchao Ying. (2019) Prognostic Potential of Alternative Splicing Markers in Endometrial Cancer. Molecular Therapy - Nucleic Acids 18, pages 1039-1048.
Crossref
Miguel Reyes, Dwayne VickersKianna Billman, Thomas EisenhaurePaul HooverEdward P. Browne, Deepak A. Rao, Nir Hacohen & Paul C. Blainey. (2019) Multiplexed enrichment and genomic profiling of peripheral blood cells reveal subset-specific immune signatures. Science Advances 5:1.
Crossref
Paul K. Drain, Kristina L. Bajema, David Dowdy, Keertan Dheda, Kogieleum Naidoo, Samuel G. Schumacher, Shuyi Ma, Erin Meermeier, David M. Lewinsohn & David R. Sherman. (2018) Incipient and Subclinical Tuberculosis: a Clinical Review of Early Stages and Progression of Infection. Clinical Microbiology Reviews 31:4.
Crossref
Masha G. Savelieff, Lucia Pappalardo & Panagiotis Azmanis. (2018) The current status of avian aspergillosis diagnoses: Veterinary practice to novel research avenues. Veterinary Clinical Pathology 47:3, pages 342-362.
Crossref
Raymond J. Langley & Hector R. Wong. (2017) Early Diagnosis of Sepsis: Is an Integrated Omics Approach the Way Forward?. Molecular Diagnosis & Therapy 21:5, pages 525-537.
Crossref
Masha G. Savelieff & Lucia Pappalardo. (2017) Novel cutting-edge metabolite-based diagnostic tools for aspergillosis. PLOS Pathogens 13:9, pages e1006486.
Crossref
Scott M. GordonMD, PhDMD, PhD, Lakshmi SrinivasanMBBS, MTRMBBS, MTR & Mary Catherine HarrisMDMD. (2017) Neonatal Meningitis: Overcoming Challenges in Diagnosis, Prognosis, and Treatment with Omics. Frontiers in Pediatrics 5.
Crossref
Liuyang Wang, Emily R. Ko, James J. GilchristKelly J. Pittman, Anna RautanenMatti PirinenJ. Will ThompsonLaura G. DuboisRaymond J. Langley, Sarah L. Jaslow, Raul E. SalinasD. Clayburn Rouse, M. Arthur Moseley, Salim MwarumbaPatricia NjugunaNeema MturiThomas N. Williams, J. Anthony G. Scott, Adrian V. S. HillChristopher W. Woods, Geoffrey S. GinsburgEphraim L. Tsalik & Dennis C. Ko. (2017) Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis. Science Advances 3:3.
Crossref
Nikolaos Evangelatos, Pia Bauer, Matthias Reumann, Kapaettu Satyamoorthy, Hans Lehrach & Angela Brand. (2017) Metabolomics in Sepsis and Its Impact on Public Health. Public Health Genomics 20:5, pages 274-285.
Crossref
Richard Allen WhiteIIIIII, Jessica N. Brazelton de Cárdenas & Randall T. Hayden. 2015. Current and Emerging Technologies for the Diagnosis of Microbial Infections. Current and Emerging Technologies for the Diagnosis of Microbial Infections 555 567 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.