1,105
Views
38
CrossRef citations to date
0
Altmetric
Review

Detecting cancer biomarkers in blood: challenges for new molecular diagnostic and point-of-care tests using cell-free nucleic acids

, &

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Karen E. Kempsell, Graham Ball & Tamas Szakmany. (2016) Issues in biomarker identification, validation and development for disease diagnostics in Public Health. Expert Review of Molecular Diagnostics 16:4, pages 383-386.
Read now

Articles from other publishers (37)

Nicolas P. Tessier, Lise M. Hardy, Jean-François Deleuze & Alexandre How-Kit. (2023) Circulating cell-free nucleic acids of plasma in human aging, healthy aging and longevity: current state of knowledge. Frontiers in Genetics 14.
Crossref
Songbin Liu, Cui-Yun Yu & Hua Wei. (2023) Spherical nucleic acids-based nanoplatforms for tumor precision medicine and immunotherapy. Materials Today Bio 22, pages 100750.
Crossref
Adhara Brandão Lima, Mariana Bisarro dos Reis, Marcus Matsushita, Monise Tadin dos Reis, Marco Antônio de Oliveira, Rui Manuel Reis & Denise Peixoto Guimarães. (2023) Combined SEPT9 and BMP3 methylation in plasma for colorectal cancer early detection and screening in a Brazilian population . Cancer Medicine 12:15, pages 15854-15867.
Crossref
Waqar Ahmed Afridi, Simon Strachan, Surasak Kasetsirikul, Amandeep Singh Pannu, Narshone Soda, Daniel Gough, Nam-Trung Nguyen & Muhammad J. A. Shiddiky. (2023) Potential Avenues for Exosomal Isolation and Detection Methods to Enhance Small-Cell Lung Cancer Analysis. ACS Measurement Science Au 3:3, pages 143-161.
Crossref
Phi Hung Hoang, Islam Seder, Ana Isabel Ferrer Ramírez & Sung-Jin Kim. (2022) Fluidic system with movable layers for all-in-one assay of cell-free DNA in blood. Sensors and Actuators B: Chemical 362, pages 131793.
Crossref
Abdul Muhaymin, Uzma Azeem Awan, Adnan Haider & Muhammad Naeem. 2022. Cancer Biomarkers in Diagnosis and Therapeutics. Cancer Biomarkers in Diagnosis and Therapeutics 345 365 .
Leilei Shi & Leyla Esfandiari. (2021) Emerging on‐chip electrokinetic based technologies for purification of circulating cancer biomarkers towards liquid biopsy: A review. ELECTROPHORESIS 43:1-2, pages 288-308.
Crossref
Min Li, Fangfei Yin, Lu Song, Xiuhai Mao, Fan Li, Chunhai Fan, Xiaolei Zuo & Qiang Xia. (2021) Nucleic Acid Tests for Clinical Translation. Chemical Reviews 121:17, pages 10469-10558.
Crossref
Taras Kavetskyy, Mahdieh Alipour, Oleh Smutok, Oksana Mushynska, Arnold Kiv, Dietmar Fink, Fatemeh Farshchi, Elham Ahmadian & Mohammad Hasanzadeh. (2021) Magneto-immunoassay of cancer biomarkers: Recent progress and challenges in biomedical analysis. Microchemical Journal 167, pages 106320.
Crossref
Yongxi Zhao, Xiaolei Zuo, Qian Li, Feng Chen, Yan-Ru Chen, Jinqi Deng, Da Han, Changlong Hao, Fujian Huang, Yanyi Huang, Guoliang Ke, Hua Kuang, Fan Li, Jiang Li, Min Li, Na Li, Zhenyu Lin, Dingbin Liu, Juewen Liu, Libing Liu, Xiaoguo Liu, Chunhua Lu, Fang Luo, Xiuhai Mao, Jiashu Sun, Bo Tang, Fei Wang, Jianbin Wang, Lihua Wang, Shu Wang, Lingling Wu, Zai-Sheng Wu, Fan Xia, Chuanlai Xu, Yang Yang, Bi-Feng Yuan, Quan Yuan, Chao Zhang, Zhi Zhu, Chaoyong Yang, Xiao-Bing Zhang, Huanghao Yang, Weihong Tan & Chunhai Fan. (2020) Nucleic Acids Analysis. Science China Chemistry 64:2, pages 171-203.
Crossref
Juan Pablo Hinestrosa, David J. Searson, Jean M. Lewis, Alfred Kinana, Orlando Perrera, Irina Dobrovolskaia, Kevin Tran, Robert Turner, Heath I. Balcer, Iryna Clark, David Bodkin, Dave S. B. Hoon & Rajaram Krishnan. (2020) Simultaneous Isolation of Circulating Nucleic Acids and EV-Associated Protein Biomarkers From Unprocessed Plasma Using an AC Electrokinetics-Based Platform. Frontiers in Bioengineering and Biotechnology 8.
Crossref
Bo Hoon Han, Sumi Kim, Geeyoon Seo, Youhee Heo, Seok Chung & Ji Yoon Kang. (2020) Isolation of extracellular vesicles from small volumes of plasma using a microfluidic aqueous two-phase system. Lab on a Chip 20:19, pages 3552-3559.
Crossref
Mohammad Amin Kerachian, Ali Poudineh & Jean Paul Thiery. (2019) Cell free circulating tumor nucleic acids, a revolution in personalized cancer medicine. Critical Reviews in Oncology/Hematology 144, pages 102827.
Crossref
Alka Singh, Sameer Gupta & Manisha Sachan. (2019) Epigenetic Biomarkers in the Management of Ovarian Cancer: Current Prospectives. Frontiers in Cell and Developmental Biology 7.
Crossref
Ana M. M. Rosa, Maria R. Nazaré & Duarte M. F. Prazeres. (2019) Colorimetric Detection of DNA Strands on Cellulose Microparticles Using ZZ–CBM Fusions and Gold Nanoparticles. Biotechnology Journal 14:8, pages 1800590.
Crossref
Fei Hu, Juan Li, Niancai Peng, Zheng Li, Zengming Zhang, Shuhao Zhao, Mingyue Duan, Hui Tian, Lei Li & Peng Zhang. (2019) Rapid isolation of cfDNA from large-volume whole blood on a centrifugal microfluidic chip based on immiscible phase filtration. The Analyst 144:14, pages 4162-4174.
Crossref
Augusto Márquez, Joan Aymerich, Michele Dei, Rosalía Rodríguez-Rodríguez, Manuel Vázquez-Carrera, Javier Pizarro-Delgado, Pablo Giménez-Gómez, Ángel Merlos, Lluís Terés, Francesc Serra-Graells, Cecilia Jiménez-Jorquera, Carlos Domínguez & Xavier Muñoz-Berbel. (2019) Reconfigurable multiplexed point of Care System for monitoring type 1 diabetes patients. Biosensors and Bioelectronics 136, pages 38-46.
Crossref
Ana Sofia Matias, Raquel Vinhas, Rita Mendes, Alexandra R. Fernandes & Pedro Viana Baptista. (2019) Nanoparticles as Emerging Diagnostic Tools in Liquid Tumours. EMJ Innovations, pages 80-87.
Crossref
Florence Mauger & Jörg Tost. (2019) Enhanced-ice-COLD-PCR for the Sensitive Detection of Rare DNA Methylation Patterns in Liquid Biopsies. BIO-PROTOCOL 9:23.
Crossref
Vivek Kumar, Alka Singh, Priyanka Gautam & Manisha Sachan. 2019. Biomedical Engineering and its Applications in Healthcare. Biomedical Engineering and its Applications in Healthcare 327 351 .
Fu Feng, Wang Chen, Dihan Chen, Wei Lin & Shih-Chi Chen. (2018) In-situ ultrasensitive label-free DNA hybridization detection using optical fiber specklegram. Sensors and Actuators B: Chemical 272, pages 160-165.
Crossref
Arutha Kulasinghe, Hanjie Wu, Chamindie Punyadeera & Majid Warkiani. (2018) The Use of Microfluidic Technology for Cancer Applications and Liquid Biopsy. Micromachines 9:8, pages 397.
Crossref
Jean M. Lewis, Ankit D. Vyas, Yuqi Qiu, Karen S. Messer, Rebekah White & Michael J. Heller. (2018) Integrated Analysis of Exosomal Protein Biomarkers on Alternating Current Electrokinetic Chips Enables Rapid Detection of Pancreatic Cancer in Patient Blood. ACS Nano 12:4, pages 3311-3320.
Crossref
Motoi Oishi. (2018) Comparative Study of DNA Circuit System-Based Proportional and Exponential Amplification Strategies for Enzyme-Free and Rapid Detection of miRNA at Room Temperature. ACS Omega 3:3, pages 3321-3329.
Crossref
Enrica Rampazzo, Paola Del Bianco, Roberta Bertorelle, Caterina Boso, Alessandro Perin, Giovanna Spiro, Francesca Bergamo, Claudio Belluco, Angela Buonadonna, Elisa Palazzari, Sara Leonardi, Antonino De Paoli, Salvatore Pucciarelli & Anita De Rossi. (2018) The predictive and prognostic potential of plasma telomerase reverse transcriptase (TERT) RNA in rectal cancer patients. British Journal of Cancer 118:6, pages 878-886.
Crossref
Fei Ye, Ying Zhao, Ramy El-Sayed, Mamoun Muhammed & Moustapha Hassan. (2018) Advances in nanotechnology for cancer biomarkers. Nano Today 18, pages 103-123.
Crossref
Kseniia Boriachek, Md. Nazmul Islam, Andreas Möller, Carlos Salomon, Nam‐Trung Nguyen, Md. Shahriar A. Hossain, Yusuke Yamauchi & Muhammad J. A. Shiddiky. (2017) Biological Functions and Current Advances in Isolation and Detection Strategies for Exosome Nanovesicles. Small 14:6, pages 1702153.
Crossref
Frauke Adams, Jörg-M. Hollidt & Christof Winter. 2018. Point-of-Care Testing. Point-of-Care Testing 433 438 .
Manish Kumar, Shilpee Srivastava, Seram Anil Singh, Anup Kumar Das, Ganesh Chandra Das, Bishal Dhar, Sankar Kumar Ghosh & Rosy Mondal. (2017) Cell-free mitochondrial DNA copy number variation in head and neck squamous cell carcinoma: A study of non-invasive biomarker from Northeast India. Tumor Biology 39:10, pages 101042831773664.
Crossref
Stuart D. Ibsen, Jennifer Wright, Jean M. Lewis, Sejung Kim, Seo-Yeon Ko, Jiye Ong, Sareh Manouchehri, Ankit Vyas, Johnny Akers, Clark C. Chen, Bob S. Carter, Sadik C. Esener & Michael J. Heller. (2017) Rapid Isolation and Detection of Exosomes and Associated Biomarkers from Plasma. ACS Nano 11:7, pages 6641-6651.
Crossref
D. P. Heineck, J. M. Lewis & M. J. Heller. (2017) Electrokinetic device design and constraints for use in high conductance solutions. ELECTROPHORESIS 38:11, pages 1475-1482.
Crossref
Michael J. Donovan & Carlos Cordon-Cardo. (2016) Implementation of a Precision Pathology Program Focused on Oncology-Based Prognostic and Predictive Outcomes. Molecular Diagnosis & Therapy 21:2, pages 115-123.
Crossref
Janay E. Kong, Qingshan Wei, Derek Tseng, Jingzi Zhang, Eric Pan, Michael Lewinski, Omai B. Garner, Aydogan Ozcan & Dino Di Carlo. (2017) Highly Stable and Sensitive Nucleic Acid Amplification and Cell-Phone-Based Readout. ACS Nano 11:3, pages 2934-2943.
Crossref
Nurhaslina Abd Rahman, Fatimah Ibrahim & Bashar Yafouz. (2017) Dielectrophoresis for Biomedical Sciences Applications: A Review. Sensors 17:3, pages 449.
Crossref
Frauke Adams, Jörg-M. Hollidt & Christof Winter. 2017. POCT - Patientennahe Labordiagnostik. POCT - Patientennahe Labordiagnostik 435 440 .
Ting Wang, Kun-He Zhang, Piao-Ping Hu, Zeng-Yong Huang, Pan Zhang, Qin-Si Wan, De-Qiang Huang & Nong-Hua Lv. (2016) Simple and robust diagnosis of early, small and AFP-negative primary hepatic carcinomas: an integrative approach of serum fluorescence and conventional blood tests. Oncotarget 7:39, pages 64053-64070.
Crossref
Claudia Berrondo, Jonathan Flax, Victor Kucherov, Aisha Siebert, Thomas Osinski, Alex Rosenberg, Christopher Fucile, Samuel Richheimer & Carla J. Beckham. (2016) Expression of the Long Non-Coding RNA HOTAIR Correlates with Disease Progression in Bladder Cancer and Is Contained in Bladder Cancer Patient Urinary Exosomes. PLOS ONE 11:1, pages e0147236.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.