120
Views
39
CrossRef citations to date
0
Altmetric
Review

Global metabolic profiling and its role in systems biology to advance personalized medicine in the 21st Century

Pages 247-259 | Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Uwe Christians, Jost Klawitter, Jelena Klawitter, Nina Brunner & Volker Schmitz. (2011) Biomarkers of immunosuppressant organ toxicity after transplantation: status, concepts and misconceptions. Expert Opinion on Drug Metabolism & Toxicology 7:2, pages 175-200.
Read now

Articles from other publishers (38)

Yujie Ning, Sijie Chen, Feiyu Zhang, Yanli Liu, Feihong Chen, Shujin Li, Chaowei Wang, Yifan Wu, Yi Gong, Minhan Hu, Ruitian Huang, Xiong Guo, Lei Yang & Xi Wang. (2023) The alteration of urinary metabolomics profiles in Kashin–Beck disease in a three consecutive year study. Molecular Omics 19:2, pages 137-149.
Crossref
Maria S. Chumachenko, Tatsiana V. Waseem & Sergei V. Fedorovich. (2022) Metabolomics and metabolites in ischemic stroke. Reviews in the Neurosciences 33:2, pages 181-205.
Crossref
Peng‐Fei Liu, Xiaohao Li, Xin‐tong Hua & Jian‐xin Cheng. (2021) Metabolomics profiling for the identification of potential biomarkers in blood serum of Takifugu rubripes challenged with Cryptocaryon irritans . Aquaculture Research 52:9, pages 4512-4525.
Crossref
Xiao Shuiming & Zhang Xiaoyan. 2021. The Ginseng Genome. The Ginseng Genome 171 183 .
Tie Zhang, Jing Xu, Yang Liu & Jia Liu. (2019) Metabolomic profiling for identification of potential biomarkers in patients with dermatomyositis. Metabolomics 15:5.
Crossref
A Rawat, S Chaturvedi, AK Singh, A Guleria, D Dubey, AK Keshari, V Raj, A Rai, A Prakash, U Kumar, D Kumar & S Saha. (2017) Metabolomics approach discriminates toxicity index of pyrazinamide and its metabolic products, pyrazinoic acid and 5-hydroxy pyrazinoic acid. Human & Experimental Toxicology 37:4, pages 373-389.
Crossref
P.G. Lokhov, A.V. Lisitsa & A.I. Archakov. (2017) Metabolomic blood test: purpose, implementation and interpretation of data. Biomeditsinskaya Khimiya 63:3, pages 232-240.
Crossref
Yuwei Lu & Chi Chen. (2017) Metabolomics: Bridging Chemistry and Biology in Drug Discovery and Development. Current Pharmacology Reports 3:1, pages 16-25.
Crossref
U. Christians, J. Klawitter, J. Klepacki & J. Klawitter. 2017. Biomarkers of Kidney Disease. Biomarkers of Kidney Disease 33 118 .
Vasudev Kantae, Elke H. J. Krekels, Michiel J. Van Esdonk, Peter Lindenburg, Amy C. Harms, Catherijne A. J. Knibbe, Piet H. Van der Graaf & Thomas Hankemeier. (2016) Integration of pharmacometabolomics with pharmacokinetics and pharmacodynamics: towards personalized drug therapy. Metabolomics 13:1.
Crossref
Charles J.P. Snart, Ian C.W. Hardy & David A. Barrett. (2015) Entometabolomics: applications of modern analytical techniques to insect studies. Entomologia Experimentalis et Applicata 155:1, pages 1-17.
Crossref
Michele Mussap & Vassilios Fanos. 2015. General Methods in Biomarker Research and their Applications. General Methods in Biomarker Research and their Applications 457 481 .
O.P. Trifonova, P.G. Lokhov & A.I. Archakov. (2014) Metabolic profiling of human blood. Biomeditsinskaya Khimiya 60:3, pages 281-294.
Crossref
M. Mussap, A. Noto, V. Fanos & J. N. Van Den Anker. (2014) Emerging Biomarkers and Metabolomics for Assessing Toxic Nephropathy and Acute Kidney Injury (AKI) in Neonatology. BioMed Research International 2014, pages 1-16.
Crossref
Michele Mussap & Vassilios Fanos. 2014. General Methods in Biomarker Research and their Applications. General Methods in Biomarker Research and their Applications 1 20 .
Stefano Cacciatore, Xiaoyu Hu, Christian Viertler, Marcel Kap, Gerwin A. Bernhardt, Hans-Jörg Mischinger, Peter Riegman, Kurt Zatloukal, Claudio Luchinat & Paola Turano. (2013) Effects of Intra- and Post-Operative Ischemia on the Metabolic Profile of Clinical Liver Tissue Specimens Monitored by NMR. Journal of Proteome Research 12:12, pages 5723-5729.
Crossref
Oxana TrifonovaPetr LokhovAlexander Archakov. (2013) Postgenomics Diagnostics: Metabolomics Approaches to Human Blood Profiling. OMICS: A Journal of Integrative Biology 17:11, pages 550-559.
Crossref
Michele Mussap, Roberto Antonucci, Antonio Noto & Vassilios Fanos. (2013) The role of metabolomics in neonatal and pediatric laboratory medicine. Clinica Chimica Acta 426, pages 127-138.
Crossref
O. P. Trifonova, P. G. Lokhov & A. I. Archakov. (2013) Metabolic profiling of human blood. Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry 7:3, pages 179-186.
Crossref
Jeonghyeon Park, Keumhan Noh, Hae Won Lee, Mi-sun Lim, Sook Jin Seong, Jeong Ju Seo, Eun-Jung Kim, Wonku Kang & Young-Ran Yoon. (2013) Pharmacometabolomic Approach to Predict QT Prolongation in Guinea Pigs. PLoS ONE 8:4, pages e60556.
Crossref
Rahul Bohra, Jacek Klepacki, Jelena Klawitter, Jost Klawitter, Joshua M. Thurman & Uwe Christians. (2013) Proteomics and metabolomics in renal transplantation-quo vadis?. Transplant International 26:3, pages 225-241.
Crossref
Uwe Christians, Volker Schmitz, Jost Klawitter & Jelena Klawitter. 2012. Analytical Techniques for Clinical Chemistry. Analytical Techniques for Clinical Chemistry 691 774 .
Hui Sun, Aihua Zhang & Xijun Wang. (2012) Potential Role of Metabolomic Approaches for Chinese Medicine Syndromes and Herbal Medicine. Phytotherapy Research, pages n/a-n/a.
Crossref
Xijun Wang, Aihua Zhang, Hui Sun & Ping Wang. (2012) Systems Biology Technologies Enable Personalized Traditional Chinese Medicine: A Systematic Review. The American Journal of Chinese Medicine 40:06, pages 1109-1122.
Crossref
Marta Cascante, Vitaly Selivanov & Antonio Ramos-Montoya. 2012. The Handbook of Metabolomics. The Handbook of Metabolomics 299 320 .
Saura C. Sahu. 2009. General, Applied and Systems Toxicology. General, Applied and Systems Toxicology.
Hyuk Nam Kwon, Mina Kim, He Wen, Sunmi Kang, Hye-ji Yang, Myung-Joo Choi, Hee Seung Lee, DalWoong Choi, In Suh Park, Young Ju Suh, Soon-Sun Hong & Sunghyouk Park. (2011) Predicting idiopathic toxicity of cisplatin by a pharmacometabonomic approach. Kidney International 79:5, pages 529-537.
Crossref
A.E.P. Heazell, M. Brown, S.A. Worton & W.B. Dunn. (2011) Review: The effects of oxygen on normal and pre-eclamptic placental tissue – insights from metabolomics. Placenta 32, pages S119-S124.
Crossref
Lynsey MacIntyre, Liang Zheng, Paul Scullion, Pat Keating & David G. Watson. (2010) Metabolomic profiling of biomarkers of liver X receptor-induced toxicity in mouse liver tissue. Metabolomics 7:1, pages 54-70.
Crossref
Warwick B. Dunn, David I. Broadhurst, Helen J. Atherton, Royston Goodacre & Julian L. Griffin. (2011) Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy. Chem. Soc. Rev. 40:1, pages 387-426.
Crossref
Uwe Christians, Jeska Albuisson, Jost Klawitter & Jelena Klawitter. 2011. Biomarkers of Kidney Disease. Biomarkers of Kidney Disease 39 100 .
Ewa Szymańska, Michał J. Markuszewski, Marcin Markuszewski & Roman Kaliszan. (2010) Altered levels of nucleoside metabolite profiles in urogenital tract cancer measured by capillary electrophoresis. Journal of Pharmaceutical and Biomedical Analysis 53:5, pages 1305-1312.
Crossref
William J. Griffiths, Therese Koal, Yuqin Wang, Matthias Kohl, David P. Enot & Hans‐Peter Deigner. (2010) Targeted Metabolomics for Biomarker Discovery. Angewandte Chemie International Edition 49:32, pages 5426-5445.
Crossref
William J. Griffiths, Therese Koal, Yuqin Wang, Matthias Kohl, David P. Enot & Hans‐Peter Deigner. (2010) “Targeted Metabolomics” in der Biomarkerforschung. Angewandte Chemie 122:32, pages 5554-5575.
Crossref
P B Phapale, S-D Kim, H W Lee, M Lim, D D Kale, Y-L Kim, J-H Cho, D Hwang & Y-R Yoon. (2010) An Integrative Approach for Identifying a Metabolic Phenotype Predictive of Individualized Pharmacokinetics of Tacrolimus. Clinical Pharmacology & Therapeutics 87:4, pages 426-436.
Crossref
Bärbel Hüsing. (2010) Individualisierte Medizin – Potenziale und Handlungsbedarf. Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen 104:10, pages 727-731.
Crossref
Marie-Laure Anne, Caroline Le Lan, Valérie Monbet, Catherine Boussard-Plédel, Martine Ropert, Olivier Sire, Michel Pouchard, Christine Jard, Jacques Lucas, Jean Luc Adam, Pierre Brissot, Bruno Bureau & Olivier Loréal. (2009) Fiber evanescent wave spectroscopy using the mid-infrared provides useful fingerprints for metabolic profiling in humans. Journal of Biomedical Optics 14:5, pages 054033.
Crossref
Patrick Giavalisco, Jan Hummel, Jan Lisec, Alvaro Cuadros Inostroza, Gareth Catchpole & Lothar Willmitzer. (2008) High-Resolution Direct Infusion-Based Mass Spectrometry in Combination with Whole 13 C Metabolome Isotope Labeling Allows Unambiguous Assignment of Chemical Sum Formulas . Analytical Chemistry 80:24, pages 9417-9425.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.