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Drug Profiles

Current status of safinamide for the drug portfolio of Parkinson’s disease therapy

Pages 969-977 | Published online: 09 Jan 2014

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Read on this site (5)

Thomas Müller. (2016) Emerging approaches in Parkinson’s disease – adjunctive role of safinamide. Therapeutics and Clinical Risk Management 12, pages 1151-1160.
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F. Javier Álvarez. (2016) Parkinson’s disease, antiparkinson medicines, and driving. Expert Review of Neurotherapeutics 16:9, pages 1023-1032.
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Cornelis J Van der Schyf. (2015) Rational drug discovery design approaches for treating Parkinson’s disease. Expert Opinion on Drug Discovery 10:7, pages 713-741.
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Livia Dézsi & László Vécsei. (2014) Safinamide for the treatment of Parkinson's disease. Expert Opinion on Investigational Drugs 23:5, pages 729-742.
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Articles from other publishers (12)

Thomas Müller. 2022. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 2853 2870 .
Della G.T. Parambi. (2020) Treatment of Parkinson’s Disease by MAO-B Inhibitors, New Therapies and Future Challenges - A Mini-Review. Combinatorial Chemistry & High Throughput Screening 23:9, pages 847-861.
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Thomas Müller. 2019. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 1 18 .
Fábio G. Teixeira, Miguel F. Gago, Paulo Marques, Pedro Silva Moreira, Ricardo Magalhães, Nuno Sousa & António J. Salgado. (2018) Safinamide: a new hope for Parkinson’s disease?. Drug Discovery Today 23:3, pages 736-744.
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Andrew C. Flick, Hong X. Ding, Carolyn A. Leverett, Robert E. KyneJr.Jr., Kevin K. -C. Liu, Sarah J. Fink & Christopher J. O’Donnell. (2017) Synthetic Approaches to the New Drugs Approved During 2015. Journal of Medicinal Chemistry 60:15, pages 6480-6515.
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Min-Ho Nam, Moosung Park, Hyeri Park, Youngjae Kim, Seulki Yoon, Vikram Shahaji Sawant, Ji Won Choi, Jong-Hyun Park, Ki Duk Park, Sun-Joon Min, C. Justin Lee & Hyunah Choo. (2017) Indole-Substituted Benzothiazoles and Benzoxazoles as Selective and Reversible MAO-B Inhibitors for Treatment of Parkinson’s Disease. ACS Chemical Neuroscience 8:7, pages 1519-1529.
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Md Zeeshan Rasheed, Heena Tabassum & Suhel Parvez. (2016) Mitochondrial permeability transition pore: a promising target for the treatment of Parkinson’s disease. Protoplasma 254:1, pages 33-42.
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Thomas Müller. (2016) Nondopaminergic therapy of motor and nonmotor symptoms in Parkinson's disease: a clinician's perspective. Neurodegenerative Disease Management 6:5, pages 385-398.
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Simona Distinto, Rita Meleddu, Matilde Yanez, Roberto Cirilli, Giulia Bianco, Maria Luisa Sanna, Antonella Arridu, Pietro Cossu, Filippo Cottiglia, Cristina Faggi, Francesco Ortuso, Stefano Alcaro & Elias Maccioni. (2016) Drug design, synthesis, in vitro and in silico evaluation of selective monoaminoxidase B inhibitors based on 3-acetyl-2-dichlorophenyl-5-aryl-2,3-dihydro-1,3,4-oxadiazole chemical scaffold. European Journal of Medicinal Chemistry 108, pages 542-552.
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Yonghwang Ha, Jeong A Jeong, Youngsam Kim & David G. Churchill. 2016. The Alkali Metal Ions: Their Role for Life. The Alkali Metal Ions: Their Role for Life 585 601 .
Carlo Cattaneo, R. La Ferla, Erminio Bonizzoni & Marco Sardina. (2015) Long-Term Effects of Safinamide on Dyskinesia in Mid- to Late-Stage Parkinson’s Disease: A Post-Hoc Analysis. Journal of Parkinson's Disease 5:3, pages 475-481.
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Matthias D. Mertens, Sonja Hinz, Christa E. Müller & Michael Gütschow. (2014) Alkynyl–coumarinyl ethers as MAO-B inhibitors. Bioorganic & Medicinal Chemistry 22:6, pages 1916-1928.
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