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The pathomechanisms underlying Parkinson's disease

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Paul Galatsis. (2017) Leucine-rich repeat kinase 2 inhibitors: a patent review (2014-2016). Expert Opinion on Therapeutic Patents 27:6, pages 667-676.
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Abdul Qayyum Rana, Uzma S Ahmed, Zishan M Chaudry & Sai Vasan. (2015) Parkinson’s disease: a review of non-motor symptoms. Expert Review of Neurotherapeutics 15:5, pages 549-562.
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Laura Arnaldo, Aintzane Urbizu, Mònica Serradell, Carles Gaig, Ana Anillo, Mireia Gea, Dolores Vilas, Lourdes Ispierto, Amaia Muñoz-Lopetegi, Gerard Mayà, Pau Pastor, Ramiro Álvarez, Joan Santamaria, Alex Iranzo & Katrin Beyer. (2023) Peripheral α-synuclein isoforms are potential biomarkers for diagnosis and prognosis of isolated REM sleep behavior disorder. Parkinsonism & Related Disorders 115, pages 105832.
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A.R. Bentivoglio, M.R. Lo Monaco, R. Liperoti, D. Fusco, E. Di Stasio, A. Tondinelli, D. Marzullo, A. Maino, M.C. Cipriani & M.C. Silveri. (2023) Gender may be related to the side of the motor syndrome and cognition in idiopathic Parkinson's disease. Neurología (English Edition) 38:7, pages 467-474.
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A.R. Bentivoglio, M.R. Lo Monaco, R. Liperoti, D. Fusco, E. Di Stasio, A. Tondinelli, D. Marzullo, A. Maino, M.C. Cipriani & M.C. Silveri. (2023) Gender may be related to the side of the motor syndrome and cognition in idiopathic Parkinson's disease. Neurología 38:7, pages 467-474.
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Pratibha Mali, Prajakta Kamble, Chetan Aware, Suresh Suryawanshi & Jyoti Jadhav. (2023) Extraction optimization of anti-Parkinson’s medication L-DOPA and bioactive compounds from Mucuna atropurpurea (Roxb.) Wight & Arn. with biomedical potential: RSM based desirability function approach. Journal of Applied Research on Medicinal and Aromatic Plants 34, pages 100451.
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Wei-Yi Ong, Damien Meng-Kiat Leow, Deron R. Herr & Crystal Jing-Jing Yeo. (2022) What Do Randomized Controlled Trials Inform Us About Potential Disease-Modifying Strategies for Parkinson’s Disease?. NeuroMolecular Medicine 25:1, pages 1-13.
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Mingzhu Tao, Kaixin Dou, Yijie Xie, Binghui Hou & Anmu Xie. (2022) The associations of cerebrospinal fluid biomarkers with cognition, and rapid eye movement sleep behavior disorder in early Parkinson’s disease. Frontiers in Neuroscience 16.
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Mikaeel Valli, Carme Uribe, Alexander Mihaescu & Antonio P. Strafella. (2022) Neuroimaging of rapid eye movement sleep behavior disorder and its relation to Parkinson's disease. Journal of Neuroscience Research 100:10, pages 1815-1833.
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R.A. Harris. (2022) Simulation study on the physicochemical properties of Fe3O4 nanoparticles as drug delivery vehicles for dopamine replacement therapy of Parkinson’s disease. Materials Today Communications 31, pages 103829.
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BuseCagla Ari, FusunMayda Domac, GulayOzgen Kenangil, Nergis Imamova & AysegulCinar Kuskucu. (2022) The Influence of ADORA2A on Levodopa-Induced Dyskinesia. Neurology India 70:2, pages 633.
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Supriyo Choudhury, Sakhi Bhansali, Mona Tiwari & Hrishikesh Kumar. 2022. Perioperative Neuroscience. Perioperative Neuroscience 155 178 .
Hyuck Kim & Rocio Gomez-Pastor. 2023. Cell Biology and Translational Medicine, Volume 19. Cell Biology and Translational Medicine, Volume 19 35 95 .
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Victoria Monge-Fuentes, Andréia Biolchi Mayer, Marcos Robalinho Lima, Luiza Ribeiro Geraldes, Larissa Nepomuceno Zanotto, Karla Graziella Moreira, Olimpia Paschoal Martins, Henrique Luís Piva, Maria Sueli Soares Felipe, Andre Correa Amaral, Anamélia Lorenzetti Bocca, Antonio Claudio Tedesco & Márcia Renata Mortari. (2021) Dopamine-loaded nanoparticle systems circumvent the blood–brain barrier restoring motor function in mouse model for Parkinson’s Disease. Scientific Reports 11:1.
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Vibeke D. Valderhaug, Kristine Heiney, Ola Huse Ramstad, Geir Bråthen, Wei-Li Kuan, Stefano Nichele, Axel Sandvig & Ioanna Sandvig. (2021) Early functional changes associated with alpha-synuclein proteinopathy in engineered human neural networks. American Journal of Physiology-Cell Physiology 320:6, pages C1141-C1152.
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Merve Kasap & Donard S. Dwyer. (2021) Na+ leak-current channel (NALCN) at the junction of motor and neuropsychiatric symptoms in Parkinson’s disease. Journal of Neural Transmission 128:6, pages 749-762.
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Diego Santos‐García, Fonticoba T. De Deus, Bartolome C. Cores, Aymerich L. Valdés, Castro E. Suárez, Ángel Aneiros, Silvia Jesús, Miquel Aguilar, Pau Pastor, Lluís Planellas, Marina Cosgaya, Caldente J. García, Nuria Caballol, Inés Legarda, Vara J. Hernández, Iria Cabo, Manzanares L. López, Aramburu I. González, Rivera M. A. Ávila, Catalán M. José, Víctor Nogueira, Víctor Puente, Moreno J. M. García, Carmen Borrué, Vila B. Solano, Sauco M. Álvarez, Lydia Vela, Sonia Escalante, Esther Cubo, Padilla F. Carrillo, Castrillo J. C. Martínez, Alonso P. Sánchez, Losada M. G. Alonso, Ariztegui N. López, Itziar Gastón, Jaime Kulisevsky, Estrada M. Blázquez, Manuel Seijo, Martínez J. Rúiz, Caridad Valero, Mónica Kurtis, Oriol de Fábregues‐Boixar, Ardura J. González, Jurczynska C. Prieto, Díaz L. López, Darrian McAfee & Pablo Mir. (2020) Mood in Parkinson's disease: From early‐ to late‐stage disease. International Journal of Geriatric Psychiatry 36:5, pages 627-646.
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Jackson Tyler Boonstra, Stijn Michielse, Yasin Temel, Govert Hoogland & Ali Jahanshahi. (2020) Neuroimaging Detectable Differences between Parkinson's Disease Motor Subtypes: A Systematic Review. Movement Disorders Clinical Practice 8:2, pages 175-192.
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Nitu Dogra, Ruchi Jakhmola Mani & Deepshikha Pande Katare. (2021) Protein Interaction Studies for Understanding the Tremor Pathway in Parkinson’s Disease. CNS & Neurological Disorders - Drug Targets 19:10, pages 780-790.
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Knud Larsen, Rikke Bæk, Cagla Sahin, Lars Kjær, Gunna Christiansen, Janni Nielsen, Leila Farajzadeh & Daniel E. Otzen. (2021) Molecular characteristics of porcine alpha-synuclein splicing variants. Biochimie 180, pages 121-133.
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Akhlaq A. Farooqui. 2021. Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders. Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders 1 40 .
Veronika Filyushkina, Valentin Popov, Vadim Ushakov, Artem Batalov, Alexey Tomskiy, Igor Pronin & Alexey Sedov. 2021. Advances in Cognitive Research, Artificial Intelligence and Neuroinformatics. Advances in Cognitive Research, Artificial Intelligence and Neuroinformatics 589 602 .
Sarah J. Kann, Chiapei Chang, Peter Manza & Hoi-Chung Leung. (2020) Akinetic rigid symptoms are associated with decline in a cortical motor network in Parkinson’s disease. npj Parkinson's Disease 6:1.
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Chiung Mei Chen, Chih-Hsin Lin, Yih-Ru Wu, Chien-Yu Yen, Yu-Ting Huang, Jia-Lan Lin, Chung-Yin Lin, Wan-Ling Chen, Chih-Ying Chao, Guey-Jen Lee-Chen, Ming-Tsan Su & Kuo-Hsuan Chang. (2020) Lactulose and Melibiose Inhibit α-Synuclein Aggregation and Up-Regulate Autophagy to Reduce Neuronal Vulnerability. Cells 9:5, pages 1230.
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Ji-Hyun Choi, Jong-Min Kim, Hee Kyung Yang, Hyo-Jung Lee, Cheol Min Shin, Seong Jin Jeong, Won-Seok Kim, Ji Won Han, In-Young Yoon, Yoo Sung Song & Yun Jung Bae. (2020) Clinical Perspectives of Parkinson's Disease for Ophthalmologists, Otorhinolaryngologists, Cardiologists, Dentists, Gastroenterologists, Urologists, Physiatrists, and Psychiatrists. Journal of Korean Medical Science 35:28.
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Shamini Vijayakumaran, Yasuko Nakamura, Jeremy M. Henley & Dean L. Pountney. (2019) Ginkgolic acid promotes autophagy-dependent clearance of intracellular alpha-synuclein aggregates. Molecular and Cellular Neuroscience 101, pages 103416.
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Shakshi Sharma, Anupam Awasthi & Shamsher Singh. (2019) Altered gut microbiota and intestinal permeability in Parkinson’s disease: Pathological highlight to management. Neuroscience Letters 712, pages 134516.
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Daniel F. Manvich, Alyssa K. Petko, Rachel C. Branco, Stephanie L. Foster, Kirsten A. Porter-Stransky, Kristen A. Stout, Amy H. Newman, Gary W. Miller, Carlos A. Paladini & David Weinshenker. (2019) Selective D2 and D3 receptor antagonists oppositely modulate cocaine responses in mice via distinct postsynaptic mechanisms in nucleus accumbens. Neuropsychopharmacology 44:8, pages 1445-1455.
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Farzaneh Ghazi Sherbaf, Mahtab Mojtahed Zadeh, Maryam Haghshomar & Mohammad Hadi Aarabi. (2018) Posterior limb of the internal capsule predicts poor quality of life in patients with Parkinson’s disease: connectometry approach. Acta Neurologica Belgica 119:1, pages 95-100.
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Merrill R. Landers, James W. Navalta, Andrew S. Murtishaw, Jefferson W. Kinney & Sarah Pirio Richardson. (2019) A High-Intensity Exercise Boot Camp for Persons With Parkinson Disease: A Phase II, Pragmatic, Randomized Clinical Trial of Feasibility, Safety, Signal of Efficacy, and Disease Mechanisms. Journal of Neurologic Physical Therapy 43:1, pages 12-25.
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Lukas Hensel, Felix Hoffstaedter, Julian Caspers, Jochen Michely, Christian Mathys, Julia Heller, Claudia R Eickhoff, Kathrin Reetz, Martin Südmeyer, Gereon R Fink, Alfons Schnitzler, Christian Grefkes & Simon B Eickhoff. (2019) Functional Connectivity Changes of Key Regions for Motor Initiation in Parkinson’s Disease. Cerebral Cortex 29:1, pages 383-396.
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Charlotte Spay, Garance Meyer, Marie-Laure Welter, Brian Lau, Philippe Boulinguez & Bénédicte Ballanger. (2019) Functional imaging correlates of akinesia in Parkinson's disease: Still open issues. NeuroImage: Clinical 21, pages 101644.
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Patrik Fazio & Andrea Varrone. 2019. PET/CT in Brain Disorders. PET/CT in Brain Disorders 49 64 .
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B. M. Morberg, A. S. Malling, B. R. Jensen, O. Gredal, P. Bech & L. Wermuth. (2018) Effects of transcranial pulsed electromagnetic field stimulation on quality of life in Parkinson's disease. European Journal of Neurology 25:7, pages 963-e74.
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Patrik Fazio, Per Svenningsson, Zsolt Cselényi, Christer Halldin, Lars Farde & Andrea Varrone. (2018) Nigrostriatal dopamine transporter availability in early Parkinson's disease. Movement Disorders 33:4, pages 592-599.
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