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Ultrasound-guided botulinum toxin injections in neurology: technique, indications and future perspectives

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Kirsten E. Zeuner, Arne Knutzen, Carina Kühl, Bettina Möller, Helge Hellriegel, Nils G. Margraf, Günther Deuschl & Henning Stolze. (2017) Functional impact of different muscle localization techniques for Botulinum neurotoxin A injections in clinical routine management of post-stroke spasticity. Brain Injury 31:1, pages 75-82.
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Articles from other publishers (44)

Chen Xin, Baoxu Li, Dezheng Wang, Wei Chen, Shouwei Yue, Dong Meng, Xu Qiao & Yang Zhang. (2023) Deep learning for the rapid automatic segmentation of forearm muscle boundaries from ultrasound datasets. Frontiers in Physiology 14.
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Laura C. Scholtz, Jon Rosenberg, Matthew S. Robbins, Tanping Wong, Gregory Mints, Aaron Kaplan, Dora Leung, Hooman Kamel & Judy H. Ch'ang. (2023) Ultrasonography in neurology: A comprehensive analysis and review. Journal of Neuroimaging 33:4, pages 511-520.
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Uwe Walter. (2023) Muscle Ultrasound in Clinical Neurology: Diagnostic Uses and Guidance of Botulinum Toxin Injection. Journal of Neurosonology and Neuroimaging 15:1, pages 38-53.
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Evridiki Asimakidou & Christos Sidiropoulos. (2023) A Bayesian Network Meta-Analysis and Systematic Review of Guidance Techniques in Botulinum Toxin Injections and Their Hierarchy in the Treatment of Limb Spasticity. Toxins 15:4, pages 256.
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Joshua A. Vova, Michael M. Green, Joline E. Brandenburg, Loren Davidson, Andrea Paulson, Supreet Deshpande, Joyce L. Oleszek, Didem Inanoglu & Matthew J. McLaughlin. (2021) A consensus statement on the use of botulinum toxin in pediatric patients. PM&R 14:9, pages 1116-1142.
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Uwe Walter. (2022) Ultrasound-guided medical procedures: a growing field with new opportunities. Ultraschall in der Medizin - European Journal of Ultrasound 43:04, pages 327-331.
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Jurgita Valaikiene, Felix Schlachetzki, Elsa Azevedo, Manfred Kaps, Piergiorgio Lochner, Aristeidis H. Katsanos, Uwe Walter, Claudio Baracchini, Eva Bartels & David Školoudík. (2022) Point-of-Care Ultrasound in Neurology – Report of the EAN SPN/ESNCH/ERcNsono Neuro-POCUS Working Group. Ultraschall in der Medizin - European Journal of Ultrasound 43:04, pages 354-366.
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Dirk Dressler & Eric A. Johnson. (2022) Botulinum toxin therapy: past, present and future developments. Journal of Neural Transmission 129:5-6, pages 829-833.
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Sharon Bushi, Steven Kirshblum, Tiffany Ezepue & Rex Ma. (2022) Perceived Benefits of a Cadaver-Based Ultrasound Procedure Workshop for Physical Medicine and Rehabilitation Trainees. American Journal of Physical Medicine & Rehabilitation 101:2, pages e18-e21.
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Zhijin Li, Yanlong Yang, Nanze Yu, Wenzhe Zhou, Zirong Li, Yuming Chong, Yuwei Zhang, Hayson Chenyu Wang, Cheng Chen, Xiao Long & Xiaojun Wang. (2021) The “Visible” Muscles on Ultrasound Imaging Make Botulinum Toxin Injection More Precise: A Systematic Review. Aesthetic Plastic Surgery 46:1, pages 406-418.
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Wei-Ting Wu, Ke-Vin Chang, Hsiang-Chi Chang, Lan-Rong Chen, Chen-Hsiang Kuan, Jung-Ting Kao, Ling-Ying Wei, Yunn-Jy Chen, Der-Sheng Han & Levent Özçakar. (2022) Ultrasound Imaging of the Facial Muscles and Relevance with Botulinum Toxin Injections: A Pictorial Essay and Narrative Review. Toxins 14:2, pages 101.
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Raja Mehanna & Joseph Jankovic. 2022. Handbook of Neurotoxicity. Handbook of Neurotoxicity 1095 1143 .
A. P. Kovalenko, Z. A. Zalyalova & A. F. Ivolgin. (2021) Novel approaches to the treatment of cervical dystonia. The concept of dual navigation control. Neurology, Neuropsychiatry, Psychosomatics 13:6, pages 124-131.
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Elena Pescarini, Daniel P. Butler, Aude Perusseau-Lambert, Charles Nduka & Ruben Y. Kannan. (2021) Targeted chemodenervation of the posterior belly of the digastric muscle for the management of jaw discomfort in facial synkinesis. Journal of Plastic, Reconstructive & Aesthetic Surgery 74:12, pages 3437-3442.
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Stefania Spina, Salvatore Facciorusso, Chiara Botticelli, Domenico Intiso, Maurizio Ranieri, Antonio Colamaria, Pietro Fiore, Chiara Ciritella, François Genêt & Andrea Santamato. (2021) Ultrasonographic Evaluation of Three Approaches for Botulinum Toxin Injection into Tibialis Posterior Muscle in Chronic Stroke Patients with Equinovarus Foot: An Observational Study. Toxins 13:11, pages 829.
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A. Presedo. (2021) Utilisation de la toxine botulique pour le traitement de la spasticité du membre inférieur chez l’enfant : revue de la littérature. Motricité Cérébrale 42:3, pages 75-82.
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Madeleine P. Strohl, Chia‐Fan Chang, William R. Ryan & Jolie L. Chang. (2021) Botulinum toxin for chronic parotid sialadenitis: A case series and systematic review. Laryngoscope Investigative Otolaryngology 6:3, pages 404-413.
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Urban M. Fietzek, Devavrat Nene, Axel Schramm, Silke Appel-Cresswell, Zuzana Košutzká, Uwe Walter, Jörg Wissel, Steffen Berweck, Sylvain Chouinard & Tobias Bäumer. (2021) The Role of Ultrasound for the Personalized Botulinum Toxin Treatment of Cervical Dystonia. Toxins 13:5, pages 365.
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Nicholas Dias, Chuan Zhang, Christopher P. Smith, H. Henry Lai & Yingchun Zhang. (2020) High-density surface electromyographic assessment of pelvic floor hypertonicity in IC/BPS patients: a pilot study. International Urogynecology Journal 32:5, pages 1221-1228.
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Dirk Dressler, Fereshte Adib Saberi & Raymond L. Rosales. (2020) Botulinum toxin therapy of dystonia. Journal of Neural Transmission 128:4, pages 531-537.
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Raja Mehanna & Joseph Jankovic. 2021. Handbook of Neurotoxicity. Handbook of Neurotoxicity 1 48 .
Yun Dam Ko, Soo In Yun, Dahye Ryoo, Myung Eun Chung & Jihye Park. (2020) Accuracy of Ultrasound-Guided and Non-guided Botulinum Toxin Injection Into Neck Muscles Involved in Cervical Dystonia: A Cadaveric Study. Annals of Rehabilitation Medicine 44:5, pages 370-377.
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Anna Kutschenko, Martin Klietz, Lejla Paracka, Katja Kollewe, Annika Schulte-Sutum, Theda Janssen, Christoph Schrader, Florian Wegner & Dirk Dressler. (2020) Dysphagia in cervical dystonia patients receiving optimised botulinum toxin therapy: a single-center retrospective cohort study. Journal of Neural Transmission 127:8, pages 1161-1165.
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Cemre S. Kaya, Evrim O. Yılmaz, Zeynep D. Akdeniz-Doğan & Can A. Yucesoy. (2020) Long-Term Effects With Potential Clinical Importance of Botulinum Toxin Type-A on Mechanics of Muscles Exposed. Frontiers in Bioengineering and Biotechnology 8.
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Isil Fazilet Turna, Belgin Erhan, Necibe Berrin Gunduz & Onder Turna. (2018) The effects of different injection techniques of botulinum toxin a in post-stroke patients with plantar flexor spasticity. Acta Neurologica Belgica 120:3, pages 639-643.
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. 2020. Diagnostik und Therapie neurologischer Erkrankungen. Diagnostik und Therapie neurologischer Erkrankungen 551 631 .
A. García Ron, R. Gallardo & B. Huete Hernani. (2019) Utility of ultrasound-guided injection of botulinum toxin type A for muscle imbalance in children with obstetric brachial plexus palsy: description of the procedure and action protocol. Neurología (English Edition) 34:4, pages 215-223.
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A. García Ron, R. Gallardo & B. Huete Hernani. (2019) Utilidad del tratamiento con infiltraciones ecoguiadas de toxina botulínica A en el desequilibrio muscular de niños con parálisis obstétrica del plexo braquial. Descripción del procedimiento y protocolo de actuación. Neurología 34:4, pages 215-223.
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Uwe Walter & Panagiota Tsiberidou. (2019) Differential age-, gender-, and side-dependency of vagus, spinal accessory, and phrenic nerve calibers detected with precise ultrasonography measures. Muscle & Nerve 59:4, pages 486-491.
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S. Jesús Maestre. (2019) Trastornos del movimiento. Etiopatogenia. Clasificación. Síndromes coreicos y distonía. Medicine - Programa de Formación Médica Continuada Acreditado 12:73, pages 4259-4272.
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Jean K. Mah & Nens van Alfen. (2018) Neuromuscular Ultrasound: Clinical Applications and Diagnostic Values. Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 45:6, pages 605-619.
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Genevieve Lynn Tan Yu & Raymond L. Rosales. (2018) Treatment of oromandibular dystonia using botulinum toxin injections – Case series and illustrative muscle targeting. Basal Ganglia 13, pages 7-16.
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Uwe Walter, Ales Dudesek & Urban M. Fietzek. (2018) A simplified ultrasonography-guided approach for neurotoxin injection into the obliquus capitis inferior muscle in spasmodic torticollis. Journal of Neural Transmission 125:7, pages 1037-1042.
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E. M. Nesbitt-Hawes, H. P. Dietz & J. A. Abbott. (2018) Four-dimensional ultrasound guidance for pelvic floor Botulinum toxin-A injection in chronic pelvic pain: a novel technique. Ultrasound in Obstetrics & Gynecology 51:3, pages 396-400.
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Katharine Alter & Barbara Karp. (2017) Ultrasound Guidance for Botulinum Neurotoxin Chemodenervation Procedures. Toxins 10:1, pages 18.
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Dirk Dressler & Fereshte Adib Saberi. (2017) Economics of botulinum toxin therapy: influence of the abobotulinumtoxinA package size on the costs of botulinum toxin therapy. Journal of Clinical Movement Disorders 4:1.
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Andrea Santamato & Francesco Panza. (2017) Benefits and Risks of Non-Approved Injection Regimens for Botulinum Toxins in Spasticity. Drugs 77:13, pages 1413-1422.
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Kuan Luan, Jin Li & Jinglong Liu. (2017) A three dimensional ultrasound image-guided navigation system for muscle injection. A three dimensional ultrasound image-guided navigation system for muscle injection.
Hans D. Katzberg, Vera Bril & Ari Breiner. (2016) Ultrasound in Neuromuscular Disorders. Journal of Clinical Neurophysiology 33:2, pages 80-85.
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Pierangelo Barbero, Marco Busso, Marco Tinivella, Carlo Alberto Artusi, Stefania De Mercanti, Angele Cucci, Andrea Veltri, Paolo Avagnina, Andrea Calvo, Adriano Chio’, Luca Durelli & Marinella Clerico. (2015) Long-term follow-up of ultrasound-guided botulinum toxin-A injections for sialorrhea in neurological dysphagia. Journal of Neurology 262:12, pages 2662-2667.
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Axel Schramm, Tobias Bäumer, Urban Fietzek, Susanne Heitmann, Uwe Walter & Wolfgang H. Jost. (2014) Relevance of sonography for botulinum toxin treatment of cervical dystonia: an expert statement. Journal of Neural Transmission 122:10, pages 1457-1463.
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Axel Schramm. (2015) Sonographie zur Injektions- und EMG-Kontrolle. Das Neurophysiologie-Labor 37:2, pages 91-101.
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Ales Dudesek. (2015) Vorteile der ultraschallgestützten BoNT-Injektion bei zervikaler Dystonie. DNP - Der Neurologe und Psychiater 16:5, pages 19-20.
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Stephan J. Schreiber, Georgios Sakas, Velizar Kolev & Stefano de Beni. (2015) Fusion imaging in neurosonology: Clinician’s questions, technical potentials and applicability. Biomedical Engineering Letters 4:4, pages 347-354.
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