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Evaluation of the tolerability and efficacy of Sativex in multiple sclerosis

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Mauro Maccarrone, Rafael Maldonado, Miguel Casas, Thomas Henze & Diego Centonze. (2017) Cannabinoids therapeutic use: what is our current understanding following the introduction of THC, THC:CBD oromucosal spray and others?. Expert Review of Clinical Pharmacology 10:4, pages 443-455.
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Adrien Gras & Julie Broughton. (2016) A cost-effectiveness model for the use of a cannabis-derived oromucosal spray for the treatment of spasticity in multiple sclerosis. Expert Review of Pharmacoeconomics & Outcomes Research 16:6, pages 771-779.
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Carmen Martinez-PazEmilio García-Cabrera & Ángel Vilches-Arenas. (2023) Effectiveness and Safety of Cannabinoids as an Add-On Therapy in the Treatment of Resistant Spasticity in Multiple Sclerosis: A Systematic Review. Cannabis and Cannabinoid Research 8:4, pages 580-588.
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Wessam Mustafa, Nadia Elgendy, Samer Salama, Mohamed Jawad & Khaled Eltoukhy. (2021) The Effect of Cannabis on the Clinical and Cytokine Profiles in Patients with Multiple Sclerosis. Multiple Sclerosis International 2021, pages 1-10.
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Hayes Wong & Brian E. Cairns. (2019) Cannabidiol, cannabinol and their combinations act as peripheral analgesics in a rat model of myofascial pain. Archives of Oral Biology 104, pages 33-39.
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Irene Moreno-Torres, Julia Sabín-Muñoz & Antonio García-Merino. 2019. Emerging Drugs and Targets for Multiple Sclerosis. Emerging Drugs and Targets for Multiple Sclerosis 1 32 .
Coral González-García, Irene Moreno Torres, Ruth García-Hernández, Lucía Campos-Ruíz, Luis Rodríguez Esparragoza, María José Coronado, Aranzazu García Grande, Antonio García-Merino & Antonio J. Sánchez López. (2017) Mechanisms of action of cannabidiol in adoptively transferred experimental autoimmune encephalomyelitis. Experimental Neurology 298, pages 57-67.
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Pasquale Annunziata, Chiara Cioni, Claudia Mugnaini & Federico Corelli. (2017) Potent immunomodulatory activity of a highly selective cannabinoid CB2 agonist on immune cells from healthy subjects and patients with multiple sclerosis. Journal of Neuroimmunology 303, pages 66-74.
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Uwe K. Zettl, Paulus Rommer, Petra Hipp & Robert Patejdl. (2015) Evidence for the efficacy and effectiveness of THC-CBD oromucosal spray in symptom management of patients with spasticity due to multiple sclerosis. Therapeutic Advances in Neurological Disorders 9:1, pages 9-30.
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Paulus Stefan Rommer, Frank Kamin, Mazen Abu‐Mugheisib, Wolfgang Koehler, Frank Hoffmann, Alexander Winkelmann, Reiner Benecke & Uwe Klaus Zettl. (2015) Long‐Term Effects of Repeated Cycles of Intrathecal Triamcinolone Acetonide on Spasticity in MS Patients . CNS Neuroscience & Therapeutics 22:1, pages 74-79.
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S M Todd & J C Arnold. (2016) Neural correlates of interactions between cannabidiol and Δ 9 -tetrahydrocannabinol in mice: implications for medical cannabis . British Journal of Pharmacology 173:1, pages 53-65.
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