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SPECIAL FOCUS: Alzheimer's Disease Therapy - Review

A pivotal moment in Alzheimer’s disease and dementia: how global unity of purpose and action can beat the disease by 2025

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Diane Stephenson. (2015) Alzheimer’s disease: current and future therapy. Expert Review of Neurotherapeutics 15:1, pages 1-2.
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Sachin Kammula, Sulagna Tripathi, Ning Wang, Valina L. Dawson, Ted M. Dawson & Xiaobo Mao. (2023) Unraveling the tau puzzle: a review of mechanistic targets and therapeutic interventions to prevent tau pathology in Alzheimer’s disease. Ageing and Neurodegenerative Diseases 3:4.
Crossref
Tiago Sousa, Paula I. Moreira & Susana Cardoso. (2023) Current Advances in Mitochondrial Targeted Interventions in Alzheimer’s Disease. Biomedicines 11:9, pages 2331.
Crossref
Chiara C. Brück, Frank J. Wolters, Mohammad Arfan Ikram & Inge M. C. M. de Kok. (2023) Projections of costs and quality adjusted life years lost due to dementia from 2020 to 2050: A population‐based microsimulation study. Alzheimer's & Dementia.
Crossref
Gopi Battineni, Mohmmad Amran Hossain, Nalini Chintalapudi, Enea Traini, Venkata Rao Dhulipalla, Mariappan Ramasamy & Francesco Amenta. (2021) Improved Alzheimer’s Disease Detection by MRI Using Multimodal Machine Learning Algorithms. Diagnostics 11:11, pages 2103.
Crossref
Rohmad Yudi Utomo, Yasunobu Asawa, Satoshi Okada, Hyun Seung Ban, Atsushi Yoshimori, Jürgen Bajorath & Hiroyuki Nakamura. (2021) Development of curcumin-based amyloid β aggregation inhibitors for Alzheimer's disease using the SAR matrix approach. Bioorganic & Medicinal Chemistry 46, pages 116357.
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Olakunle J. Onaolapo, Anthony T. Olofinnade, Folusho O. Ojo & Adejoke Y. Onaolapo. (2021) Neuroinflammation and Oxidative Stress in Alzheimer’s Disease; Can Nutraceuticals and Functional Foods Come to the Rescue?. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 21:2, pages 75-89.
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Agnieszka Jankowska, Maciej Pawłowski & Grażyna Chłoń-Rzepa. (2021) Diabetic Theory in Anti-Alzheimer’s Drug Research and Development. Part 2: Therapeutic Potential of cAMP-Specific Phosphodiesterase Inhibitors. Current Medicinal Chemistry 28:18, pages 3535-3553.
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Feng-mao An, Zheng Liu, Xin-ran Xuan, Qing-shan Liu & Cheng-xi Wei. (2021) Sanweidoukou decoction, a Chinese herbal formula, ameliorates β-amyloid protein-induced neuronal insult via modulating MAPK/NF-κB signaling pathways: Studies in vivo and in vitro. Journal of Ethnopharmacology 273, pages 114002.
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Jay Kant Yadav. 2021. Nutraceuticals in Brain Health and Beyond. Nutraceuticals in Brain Health and Beyond 391 408 .
Agnieszka Jankowska, Anna Wesołowska, Maciej Pawłowski & Grażyna Chłoń-Rzepa. (2020) Multifunctional Ligands Targeting Phosphodiesterase as the Future Strategy for the Symptomatic and Disease-Modifying Treatment of Alzheimer’s Disease. Current Medicinal Chemistry 27:32, pages 5351-5373.
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Robert Howard, Olga Zubko, Richard Gray, Rosie Bradley, Emma Harper, Linda Kelly, Lynn Pank, John O’Brien, Chris Fox, Naji Tabet, Gill Livingston, Peter Bentham, Rupert McShane, Alistair Burns, Craig Ritchie, Suzanne Reeves, Simon Lovestone, Clive Ballard, Wendy Noble, Gordon Wilcock & Ramin Nilforooshan. (2020) Minocycline 200 mg or 400 mg versus placebo for mild Alzheimer’s disease: the MADE Phase II, three-arm RCT. Efficacy and Mechanism Evaluation 7:2, pages 1-62.
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J.-P. Michel. (2020) Impact sociétal de la maladie d’Alois Alzheimer. Bulletin de l'Académie Nationale de Médecine 204:3, pages 214-216.
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Robert Howard, Olga Zubko, Rosie Bradley, Emma Harper, Lynn Pank, John O’Brien, Chris Fox, Naji Tabet, Gill Livingston, Peter Bentham, Rupert McShane, Alistair Burns, Craig Ritchie, Suzanne Reeves, Simon Lovestone, Clive Ballard, Wendy Noble, Ramin Nilforooshan, Gordon Wilcock & Richard Gray. (2020) Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease. JAMA Neurology 77:2, pages 164.
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Walia Zahra, Sachchida Nand Rai, Hareram Birla, Saumitra Sen Singh, Hagera Dilnashin, Aaina Singh Rathore & Surya Pratap Singh. 2020. Bioeconomy for Sustainable Development. Bioeconomy for Sustainable Development 333 345 .
Aristidis G. Vrahatis, Ilias S. Kotsireas & Panayiotis Vlamos. 2020. GeNeDis 2018. GeNeDis 2018 303 314 .
David S. Reynolds. (2019) A short perspective on the long road to effective treatments for Alzheimer's disease. British Journal of Pharmacology 176:18, pages 3636-3648.
Crossref
Oscar J. Wambuguh. 2019. Examining the Causal Relationship Between Genes, Epigenetics, and Human Health. Examining the Causal Relationship Between Genes, Epigenetics, and Human Health 468 528 .
Andrei Dragomir, Aristidis G. Vrahatis & Anastasios Bezerianos. (2019) A Network-Based Perspective in Alzheimer's Disease: Current State and an Integrative Framework. IEEE Journal of Biomedical and Health Informatics 23:1, pages 14-25.
Crossref
Zuo-Teng Wang, Chen-Chen Tan, Lan Tan & Jin-Tai Yu. (2019) Systems biology and gene networks in Alzheimer’s disease. Neuroscience & Biobehavioral Reviews 96, pages 31-44.
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Lesha Pretorius, Douglas B. Kell & Etheresia Pretorius. (2018) Iron Dysregulation and Dormant Microbes as Causative Agents for Impaired Blood Rheology and Pathological Clotting in Alzheimer’s Type Dementia. Frontiers in Neuroscience 12.
Crossref
Man Ki Kwok, Shi Lin Lin & C. Mary Schooling. (2018) Re-thinking Alzheimer's disease therapeutic targets using gene-based tests. EBioMedicine 37, pages 461-470.
Crossref
Jeffrey Cummings, Carl Reiber & Parvesh Kumar. (2018) The price of progress: Funding and financing Alzheimer's disease drug development. Alzheimer's & Dementia: Translational Research & Clinical Interventions 4:1, pages 330-343.
Crossref
Jeffrey Cummings, Paul S. Aisen, Bruno DuBois, Lutz Frölich, Clifford R. JackJrJr, Roy W. Jones, John C. Morris, Joel Raskin, Sherie A. Dowsett & Philip Scheltens. (2016) Drug development in Alzheimer’s disease: the path to 2025. Alzheimer's Research & Therapy 8:1.
Crossref
Wei Xu, Li Yang & Ji Li. (2016) Protection against β-amyloid-induced neurotoxicity by naturally occurring Z-ligustilide through the concurrent regulation of p38 and PI3-K/Akt pathways. Neurochemistry International 100, pages 44-51.
Crossref
Etheresia Pretorius, Janette Bester & Douglas B. Kell. (2016) A Bacterial Component to Alzheimer’s-Type Dementia Seen via a Systems Biology Approach that Links Iron Dysregulation and Inflammagen Shedding to Disease. Journal of Alzheimer's Disease 53:4, pages 1237-1256.
Crossref
Haruhiko Sugino, Akihito Watanabe, Naoki Amada, Miho Yamamoto, Yuta Ohgi, Dusan Kostic & Raymond Sanchez. (2015) Global Trends in Alzheimer Disease Clinical Development: Increasing the Probability of Success. Clinical Therapeutics 37:8, pages 1632-1642.
Crossref

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