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Aripiprazole: pharmacology, efficacy, safety and tolerability

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Pages 297-307 | Published online: 10 Jan 2014

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Read on this site (11)

Noor A. Nahid & Julie A. Johnson. (2022) CYP2D6 pharmacogenetics and phenoconversion in personalized medicine. Expert Opinion on Drug Metabolism & Toxicology 18:11, pages 769-785.
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Stefano Marini. (2018) Aripiprazole-Induced Diurnal and Nocturnal Enuresis in Down’s Syndrome. Journal of Mental Health Research in Intellectual Disabilities 11:3, pages 247-250.
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Nils Eiel Steen, Monica Aas, Carmen Simonsen, Ingrid Dieset, Martin Tesli, Mari Nerhus, Erlend Gardsjord, Ragni Mørch, Ingrid Agartz, Ingrid Melle, Torill Ueland, Olav Spigset & Ole A. Andreassen. (2017) Serum levels of second-generation antipsychotics are associated with cognitive function in psychotic disorders. The World Journal of Biological Psychiatry 18:6, pages 471-482.
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Aditya Hegde, Bangalore G. Kalyani, Shyam Sundar Arumugham, Janardhanan C. Narayanaswamy, Suresh Bada Math & Y. C. Janardhan Reddy. (2017) Aripiprazole augmentation in highly treatment-resistant obsessive–compulsive disorder – experience from a specialty clinic in India . International Journal of Psychiatry in Clinical Practice 21:1, pages 67-69.
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Roger S McIntyre, Jinju Yoon, Jeanette M Jerrell & Samantha S Liauw. (2011) Aripiprazole for the maintenance treatment of bipolar disorder: a review of available evidence. Neuropsychiatric Disease and Treatment 7, pages 319-323.
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Min-Hyeon Park, Changsu Han, Chi-Un Pae, Soo-Jung Lee, Ashwin A Patkar, Praksh S Masand & Wolfgang W Fleischhacker. (2011) Aripiprazole treatment for patients with schizophrenia: from acute treatment to maintenance treatment. Expert Review of Neurotherapeutics 11:11, pages 1541-1552.
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David J Muzina. (2009) Treatment and prevention of mania in bipolar I disorder: focus on aripiprazole. Neuropsychiatric Disease and Treatment 5, pages 279-288.
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Roger S McIntyre, Joanna K Soczynska, Hanna O Woldeyohannes, Andrew Miranda & Jakub Z Konarski. (2007) Aripiprazole: pharmacology and evidence in bipolar disorder. Expert Opinion on Pharmacotherapy 8:7, pages 1001-1009.
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Margarita García-Amador, Isabella Pacchiarotti, Marc Valentí, Raul F Sanchez, Jose M Goikolea & Eduard Vieta. (2006) Role of aripiprazole in treating mood disorders. Expert Review of Neurotherapeutics 6:12, pages 1777-1783.
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James M Stone & Lyn S Pilowsky. (2006) Antipsychotic drug action: targets for drug discovery with neurochemical imaging. Expert Review of Neurotherapeutics 6:1, pages 57-64.
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Articles from other publishers (25)

Hui Wu, Spyridon Siafis, Dongfang Wang, Angelika Burschinski, Johannes Schneider-Thoma, Josef Priller, John M. Davis & Stefan Leucht. (2023) Antipsychotic-induced akathisia in adults with acute schizophrenia: A systematic review and dose-response meta-analysis. European Neuropsychopharmacology 72, pages 40-49.
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Octavian Vasiliu. (2022) Third-generation antipsychotics in patients with schizophrenia and non-responsivity or intolerance to clozapine regimen: What is the evidence?. Frontiers in Psychiatry 13.
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Li Qian, Liao Xuemei, Li Jitao, Su Yun'Ai & Si Tianmei. (2021) Dose-Dependent Efficacy of Aripiprazole in Treating Patients With Schizophrenia or Schizoaffective Disorder: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Frontiers in Psychiatry 12.
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Paula Soria-Chacartegui, Gonzalo Villapalos-García, Pablo Zubiaur, Francisco Abad-Santos & Dora Koller. (2021) Genetic Polymorphisms Associated With the Pharmacokinetics, Pharmacodynamics and Adverse Effects of Olanzapine, Aripiprazole and Risperidone. Frontiers in Pharmacology 12.
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Mario Rossi, Irene Fasciani, Francesco Marampon, Roberto Maggio & Marco Scarselli. (2017) The First Negative Allosteric Modulator for Dopamine D 2 and D 3 Receptors, SB269652 May Lead to a New Generation of Antipsychotic Drugs . Molecular Pharmacology 91:6, pages 586-594.
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Eric Prommer. (2016) Aripiprazole. American Journal of Hospice and Palliative Medicine® 34:2, pages 180-185.
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Danuta Szkutnik-Fiedler, Krzysztof Kus, Piotr Ratajczak, Michał Antoniów, Elżbieta Nowakowska & Edmund Grześkowiak. (2016) Coadministration of tramadol with aripiprazole and venlafaxine—The effect on spatial memory functions in male rats. Pharmacological Reports 68:2, pages 451-456.
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. 2016. Meyler's Side Effects of Drugs. Meyler's Side Effects of Drugs 676 685 .
Minli Zhang, Ryan Eismin, Hilkka Kenttämaa, Hui Xiong, Ye Wu, Doug Burdette & Rebecca Urbanek. (2015) Identification of 2-Aminothiazolobenzazepine Metabolites in Human, Rat, Dog, and Monkey Microsomes by Ion-Molecule Reactions in Linear Quadrupole Ion Trap Mass Spectrometry. Drug Metabolism and Disposition 43:3, pages 358-366.
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Ather Muneer. (2014) Aripiprazole in the Treatment of Refractory Mood Disorders: A Case Series. Clinical Psychopharmacology and Neuroscience 12:2, pages 157-159.
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Elżbieta Nowakowska, Krzysztof Kus, Piotr Ratajczak, Michał Cichocki & Anna Woźniak. (2014) The influence of aripiprazole, olanzapine and enriched environment on depressant-like behavior, spatial memory dysfunction and hippocampal level of BDNF in prenatally stressed rats. Pharmacological Reports 66:3, pages 404-411.
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Carina J. Bleickardt, Tatiana M. Kazdoba, Nicholas T. Jones, John C. Hunter & Robert A. Hodgson. (2014) Antagonism of the adenosine A2A receptor attenuates akathisia-like behavior induced with MP-10 or aripiprazole in a novel non-human primate model. Pharmacology Biochemistry and Behavior 118, pages 36-45.
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Mu-Hong Chen & Ying-Jay Liou. (2013) Aripiprazole-Associated Acute Dystonia, Akathisia, and Parkinsonism in a Patient With Bipolar I Disorder. Journal of Clinical Psychopharmacology 33:2, pages 269-270.
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Rebecca A. Urbanek, Hui Xiong, Ye Wu, William Blackwell, Gary Steelman, Jim Rosamond, Steven S. Wesolowski, James B. Campbell, Minli Zhang, Becky Brockel & Daniel V. Widzowski. (2013) Synthesis and SAR of aminothiazole fused benzazepines as selective dopamine D2 partial agonists. Bioorganic & Medicinal Chemistry Letters 23:2, pages 543-547.
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Hui Xiong, Ye Wu, Scott G. Lehr, William Blackwell, Gary Steelman, Jim Hulsizer & Rebecca A. Urbanek. (2012) Efficient and scalable synthesis of thiazole fused benzazepine as a D2 partial agonist. Tetrahedron Letters 53:44, pages 5833-5836.
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Kinga Burda, Anna Czubak, Krzysztof Kus, Elżbieta Nowakowska, Piotr Ratajczak & Jennifer Zin. (2011) Influence of aripiprazole on the antidepressant, anxiolytic and cognitive functions of rats. Pharmacological Reports 63:4, pages 898-907.
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Douglas S. Johnson, Chung Choi, Lorraine K. Fay, David A. Favor, Joseph T. Repine, Andrew D. White, Hyacinth C. Akunne, Lawrence Fitzgerald, Kim Nicholls, Bradley J. Snyder, Steven Z. Whetzel, Liming Zhang & Kevin A. Serpa. (2011) Discovery of PF-00217830: Aryl piperazine napthyridinones as D2 partial agonists for schizophrenia and bipolar disorder. Bioorganic & Medicinal Chemistry Letters 21:9, pages 2621-2625.
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Somaia Mohamed, Robert Rosenheck, Ilan Harpaz-Rotem, Douglas Leslie & Michael J. Sernyak. (2009) Duration of Pharmacotherapy with Long-Acting Injectable Risperidone in the Treatment of Schizophrenia. Psychiatric Quarterly 80:4, pages 241-249.
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. 2009. Meyler's Side Effects of Psychiatric Drugs. Meyler's Side Effects of Psychiatric Drugs 185 373 .
Shaw-Ji CHEN, Yu-Chih SHEN, Shao-Tsu CHEN & Chaucer C. H. LIN. (2008) Aripiprazole-associated dystonia in a patient with vascular dementia. Psychogeriatrics 8:4, pages 199-200.
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Mark Sanford & Lesley J Scott. (2008) Intramuscular Aripiprazole. CNS Drugs 22:4, pages 335-352.
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Paul A. Tiffin. (2007) Managing Psychotic Illness in Young People: A Practical Overview. Child and Adolescent Mental Health 12:4, pages 173-186.
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Francesca Novi, Mark J. Millan, Giovanni U. Corsini & Roberto Maggio. (2007) Partial agonist actions of aripiprazole and the candidate antipsychotics S33592, bifeprunox, N-desmethylclozapine and preclamol at dopamine D 2L receptors are modified by co-transfection of D 3 receptors: potential role of heterodimer formation . Journal of Neurochemistry 102:4, pages 1410-1424.
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I. R. De Oliveira & M. F. Juruena. (2006) Treatment of psychosis: 30 years of progress. Journal of Clinical Pharmacy and Therapeutics 31:6, pages 523-534.
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Pietro Gareri, Pasquale De Fazio, Salvatore De Fazio, Norma Marigliano, Guido Ferreri Ibbadu & Giovambattista De Sarro. (2006) Adverse Effects of Atypical Antipsychotics in the Elderly. Drugs & Aging 23:12, pages 937-956.
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