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Review

Contemporary approaches to designing and evaluating vaccines against Chlamydia

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Pages 129-146 | Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Joseph U Igietseme, Francis O Eko & Carolyn M Black. (2011) Chlamydia vaccines: recent developments and the role of adjuvants in future formulations. Expert Review of Vaccines 10:11, pages 1585-1596.
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Joseph Igietseme, Francis Eko, Qing He, Claudiu Bandea, Werner Lubitz, Adolfo Garcia-Sastre & Carolyn Black. (2005) Delivery of Chlamydia vaccines. Expert Opinion on Drug Delivery 2:3, pages 549-562.
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Articles from other publishers (32)

Shakyra Richardson, Fnu Medhavi, Tayhlor Tanner, Stephanie Lundy, Yusuf Omosun, Joseph U. Igietseme, Darin Carroll & Francis O. Eko. (2021) Cellular Basis for the Enhanced Efficacy of the Fms-Like Tyrosine Kinase 3 Ligand (FL) Adjuvanted VCG-Based Chlamydia abortus Vaccine. Frontiers in Immunology 12.
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Roshan Pais, Yusuf Omosun, Joseph U. Igietseme, Kohtaro Fujihashi & Francis O. Eko. (2019) Route of Vaccine Administration Influences the Impact of Fms-Like Tyrosine Kinase 3 Ligand (Flt3L) on Chlamydial-Specific Protective Immune Responses. Frontiers in Immunology 10.
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Roshan Pais, Yusuf Omosun, Qing He, Uriel Blas-Machado, Carolyn Black, Joseph U. Igietseme, Kohtaro Fujihashi & Francis O. Eko. (2017) Rectal administration of a chlamydial subunit vaccine protects against genital infection and upper reproductive tract pathology in mice. PLOS ONE 12:6, pages e0178537.
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Stephen K. Tyring, Mark Burnett & Frank Mwesigye. 2017. Tropical Dermatology. Tropical Dermatology 359 375 .
Tarek A. Ahmad, Amrou E. Eweida & Laila H. El-Sayed. (2016) T-cell epitope mapping for the design of powerful vaccines. Vaccine Reports 6, pages 13-22.
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Claudiu I. Bandea, Robert C. Jerris & Carolyn M. Black. 2016. Manual of Commercial Methods in Clinical Microbiology. Manual of Commercial Methods in Clinical Microbiology 175 183 .
Shoaib Ahmad. 2006. Reviews in Cell Biology and Molecular Medicine. Reviews in Cell Biology and Molecular Medicine 276 309 .
Amir Ghasemi, Mahmood Jeddi-Tehrani, Josef Mautner, Mohammad Hossein Salari & Amir-Hassan Zarnani. (2014) Immunization of mice with a novel recombinant molecular chaperon confers protection against Brucella melitensis infection. Vaccine 32:49, pages 6659-6666.
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Peter M. Gray, Gail Forrest, Thomas Wisniewski, Gene Porter, Daniel C. Freed, Julie A. DeMartino, Dennis M. Zaller, Zhiqiang Guo, Joseph Leone, Tong-Ming Fu & Kalpit A. Vora. (2012) Evidence for cyclic diguanylate as a vaccine adjuvant with novel immunostimulatory activities. Cellular Immunology 278:1-2, pages 113-119.
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Katelijn Schautteet, Evelien De Clercq, Yannick Jönsson, Stefanie Lagae, Koen Chiers, Eric Cox & Daisy Vanrompay. (2012) Protection of pigs against genital Chlamydia trachomatis challenge by parenteral or mucosal DNA immunization. Vaccine 30:18, pages 2869-2881.
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F.O. Eko, D.N. Okenu, U.P. Singh, Q. He, C. Black & J.U. Igietseme. (2011) Evaluation of a broadly protective Chlamydia–cholera combination vaccine candidate. Vaccine 29:21, pages 3802-3810.
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F.O. Eko, E. Ekong, Q. He, C.M. Black & J.U. Igietseme. (2011) Induction of immune memory by a multisubunit chlamydial vaccine. Vaccine 29:7, pages 1472-1480.
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Claire Bertelli, François Collyn, Antony Croxatto, Christian Rückert, Adam Polkinghorne, Carole Kebbi-Beghdadi, Alexander Goesmann, Lloyd Vaughan & Gilbert Greub. (2010) The Waddlia Genome: A Window into Chlamydial Biology. PLoS ONE 5:5, pages e10890.
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Hong Yu, Xiaozhou Jiang, Caixia Shen, Karuna P. Karunakaran, Janina Jiang, Nicole L. Rosin & Robert C. Brunham. (2010) Chlamydia muridarum T-Cell Antigens Formulated with the Adjuvant DDA/TDB Induce Immunity against Infection That Correlates with a High Frequency of Gamma Interferon (IFN-γ)/Tumor Necrosis Factor Alpha and IFN-γ/Interleukin-17 Double-Positive CD4 + T Cells . Infection and Immunity 78:5, pages 2272-2282.
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Yihang Li, Sudhir K. Ahluwalia, Alexandre Borovkov, Andrey Loskutov, Chengming Wang, Dongya Gao, Anil Poudel, Kathryn F. Sykes & Bernhard Kaltenboeck. (2010) Novel Chlamydia pneumoniae vaccine candidates confirmed by Th1-enhanced genetic immunization. Vaccine 28:6, pages 1598-1605.
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Eno E. Ekong, Daniel N. Okenu, Jayanti Mania-Pramanik, Qing He, Joseph U. Igietseme, Godwin A. Ananaba, Deborah Lyn, Carolyn Black & Francis O. Eko. (2009) A Vibrio cholerae ghost-based subunit vaccine induces cross-protective chlamydial immunity that is enhanced by CTA2B, the nontoxic derivative of cholera toxin . FEMS Immunology & Medical Microbiology 55:2, pages 280-291.
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Marina Jovanovic, Djordjije Karadaglic, Zoran Golusin, Silvija Brkic & Mirjana Poljacki. (2009) Experimental vaccines for sexually transmitted infections. Medicinski pregled Medical review 62:1-2, pages 42-48.
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Maria Victoria Delpino, Silvia Marcela Estein, Carlos Alberto Fossati, Pablo César Baldi & Juliana Cassataro. (2007) Vaccination with Brucella recombinant DnaK and SurA proteins induces protection against Brucella abortus infection in BALB/c mice. Vaccine 25:37-38, pages 6721-6729.
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Callum Thorpe, Lorna Edwards, Robert Snelgrove, Oretta Finco, Aaron Rae, Guido Grandi, Ratti Guilio & Tracy Hussell. (2007) Discovery of a vaccine antigen that protects mice from Chlamydia pneumoniae infection. Vaccine 25:12, pages 2252-2260.
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Carolin Biesenkamp-Uhe, Yihang Li, Hans-Robert Hehnen, Konrad Sachse & Bernhard Kaltenboeck. (2007) Therapeutic Chlamydophila abortus and C. pecorum Vaccination Transiently Reduces Bovine Mastitis Associated with Chlamydophila Infection . Infection and Immunity 75:2, pages 870-877.
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Lucinda Macmillan, Godwin O. Ifere, Qing He, Joseph U. Igietseme, Kathryn L. Kellar, Daniel M. Okenu & Francis O. Eko. (2007) A recombinant multivalent combination vaccine protects against Chlamydia and genital herpes . FEMS Immunology & Medical Microbiology 49:1, pages 46-55.
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Mary Duff. 2007. xPharm: The Comprehensive Pharmacology Reference. xPharm: The Comprehensive Pharmacology Reference 1 6 .
Radhey S. Gupta & Emma Griffiths. (2006) Chlamydiae-specific proteins and indels: novel tools for studies. Trends in Microbiology 14:12, pages 527-535.
Crossref
. 2006. Tropical Dermatology. Tropical Dermatology 359 374 .
Qing He, Terri T. Moore, Francis O. Eko, Deborah Lyn, Godwin A. Ananaba, Amy Martin, Shailesh Singh, Lillard James, Jonathan Stiles, Carolyn M. Black & Joseph U. Igietseme. (2005) Molecular Basis for the Potency of IL-10-Deficient Dendritic Cells as a Highly Efficient APC System for Activating Th1 Response. The Journal of Immunology 174:8, pages 4860-4869.
Crossref
Robert C. Brunham & José Rey-Ladino. (2005) Immunology of Chlamydia infection: implications for a Chlamydia trachomatis vaccine. Nature Reviews Immunology 5:2, pages 149-161.
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Oretta Finco, Alessandra Bonci, Mauro Agnusdei, Maria Scarselli, Roberto Petracca, Nathalie Norais, Germano Ferrari, Ignazio Garaguso, Manuela Donati, Vittorio Sambri, Roberto Cevenini, Giulio Ratti & Guido Grandi. (2005) Identification of new potential vaccine candidates against Chlamydia pneumoniae by multiple screenings. Vaccine 23:9, pages 1178-1188.
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Lisa N. Steele, Zarine R. Balsara & Michael N. Starnbach. (2004) Hematopoietic Cells Are Required to Initiate a Chlamydia trachomatis -Specific CD8+ T Cell Response . The Journal of Immunology 173:10, pages 6327-6337.
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Francis O. Eko, Qing He, Teresa Brown, Lucinda McMillan, Godwin O. Ifere, Godwin A. Ananaba, Deborah Lyn, Werner Lubitz, Kathryn L. Kellar, Carolyn M. Black & Joseph U. Igietseme. (2004) A Novel Recombinant Multisubunit Vaccine against Chlamydia . The Journal of Immunology 173:5, pages 3375-3382.
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Sheila K West. (2004) Trachoma: new assault on an ancient disease. Progress in Retinal and Eye Research 23:4, pages 381-401.
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Jorma Paavonen. (2004) Sexually transmitted chlamydial infections and subfertility. International Congress Series 1266, pages 277-286.
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Sukumar Pal, Ellena M. Peterson & Luis M. de la Maza. (2003) Induction of protective immunity against a Chlamydia trachomatis genital infection in three genetically distinct strains of mice. Immunology 110:3, pages 368-375.
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