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Exploitation of physiology and metabolomics to identify pneumococcal vaccine candidates

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Pages 1061-1075 | Published online: 09 Jan 2014

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Dabin Ren, Anthony L Almudevar & Michael E Pichichero. (2015) Synchrony in serum antibody response to conserved proteins of Streptococcus pneumoniae in young children . Human Vaccines & Immunotherapeutics 11:2, pages 489-497.
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Xinyu Liu, Congshu Xiao, Pengwei Guan, Qianqian Chen, Lei You, Hongwei Kong, Wangshu Qin, Peng Dou, Qi Li, Yanju Li, Ying Jiao, Zhiwei Zhong, Jun Yang, Xiaolin Wang, Qingqing Wang, Jinhui Zhao, Zhiliang Xu, Hong Zhang, Rongkuan Li, Peng Gao & Guowang Xu. (2023) Metabolomics acts as a powerful tool for comprehensively evaluating vaccines approved under emergency: a CoronaVac retrospective study. Frontiers in Immunology 14.
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Stephanie Hirschmann, Alejandro Gómez-Mejia, Ulrike Mäder, Julia Karsunke, Dominik Driesch, Manfred Rohde, Susanne Häussler, Gerhard Burchhardt & Sven Hammerschmidt. (2021) The Two-Component System 09 Regulates Pneumococcal Carbohydrate Metabolism and Capsule Expression. Microorganisms 9:3, pages 468.
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Mohammed R. Abdullah, María T. Batuecas, Franziska Jennert, Franziska Voß, Philipp Westhoff, Thomas P. Kohler, Rafael Molina, Stephanie Hirschmann, Michael Lalk, Juan A. Hermoso & Sven Hammerschmidt. (2021) Crystal Structure and Pathophysiological Role of the Pneumococcal Nucleoside-binding Protein PnrA. Journal of Molecular Biology 433:2, pages 166723.
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Richard B. Kennedy, Inna G. Ovsyannikova, Peter Palese & Gregory A. Poland. (2020) Current Challenges in Vaccinology. Frontiers in Immunology 11.
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Claudia Hirschfeld, Alejandro Gómez-Mejia, Jürgen Bartel, Christian Hentschker, Manfred Rohde, Sandra Maaß, Sven Hammerschmidt & Dörte Becher. (2020) Proteomic Investigation Uncovers Potential Targets and Target Sites of Pneumococcal Serine-Threonine Kinase StkP and Phosphatase PhpP. Frontiers in Microbiology 10.
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A. Leonard & M. Lalk. (2018) Infection and metabolism – Streptococcus pneumoniae metabolism facing the host environment. Cytokine 112, pages 75-86.
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Kim M. Hare, Amanda J. Leach, Heidi C. Smith-Vaughan, Anne B. Chang & Keith Grimwood. (2017) Streptococcus pneumoniae and chronic endobronchial infections in childhood . Pediatric Pulmonology 52:12, pages 1532-1545.
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Aimee Tan, John M. Atack, Michael P. Jennings & Kate L. Seib. (2016) The Capricious Nature of Bacterial Pathogens: Phasevarions and Vaccine Development. Frontiers in Immunology 7.
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Jörg Willenborg & Ralph Goethe. (2016) Metabolic traits of pathogenic streptococci. FEBS Letters 590:21, pages 3905-3919.
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Thomas P. Kohler, Annemarie Scholz, Delia Kiachludis & Sven Hammerschmidt. (2016) Induction of Central Host Signaling Kinases during Pneumococcal Infection of Human THP-1 Cells. Frontiers in Cellular and Infection Microbiology 6.
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Abiodun D. Ogunniyi & James C. Paton. 2015. Streptococcus Pneumoniae. Streptococcus Pneumoniae 59 78 .
Mathias W. Pletz & Tobias Welte. 2014. Community-Acquired Pneumonia. Community-Acquired Pneumonia 266 284 .

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