Advanced search
Publication Cover
Expert Review of Vaccines Volume 14, 2015 - Issue 4
Submit an article Journal homepage
345
Views
34
CrossRef citations to date
0
Altmetric
Original Research

DNA vaccination with genes encoding Toxoplasma gondii antigens ROP5 and GRA15 induces protective immunity against toxoplasmosis in Kunming mice

Jia ChenState Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, PR ChinaCorrespondence[email protected]
,
Zhong-Yuan LiState Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, PR China;College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang Province 163319, PR ChinaCorrespondence[email protected]
,
Eskild PetersenDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Health Sciences, Institute for Clinical Medicine, Aarhus University, Aarhus, Denmark
,
Si-Yang HuangState Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, PR China
,
Dong-Hui ZhouState Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, PR China
&
Xing-Quan ZhuState Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, PR China;College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang Province 163319, PR China;Jiangsu Co-innovation Center for the Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University College of Veterinary Medicine, Yangzhou, Jiangsu Province 225009, PR ChinaCorrespondence[email protected]
Pages 617-624 | Published online: 07 Mar 2015

Citations (34)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Yawen Li & Huaiyu Zhou. (2018) Moving towards improved vaccines for Toxoplasma gondii. Expert Opinion on Biological Therapy 18:3, pages 273-280.
Read now
Nian-Zhang Zhang, Meng Wang, Ying Xu, Eskild Petersen & Xing-Quan Zhu. (2015) Recent advances in developing vaccines against Toxoplasma gondii: an update. Expert Review of Vaccines 14:12, pages 1609-1621.
Read now
Nian-Zhang Zhang, Ying Xu, Meng Wang, Eskild Petersen, Jia Chen, Si-Yang Huang & Xing-Quan Zhu. (2015) Protective efficacy of two novel DNA vaccines expressing Toxoplasma gondii rhomboid 4 and rhomboid 5 proteins against acute and chronic toxoplasmosis in mice. Expert Review of Vaccines 14:9, pages 1289-1297.
Read now

Articles from other publishers (31)

Youbo Shi, Jianbing Li, Weili Yang & Jia Chen. (2023) Protective immunity induced by DNA vaccine containing TgGRA35, TgGRA42, and TgGRA43 against Toxoplasma gondii infection in Kunming mice. Frontiers in Cellular and Infection Microbiology 13.
Crossref
Thabile Madlala, Victoria T. Adeleke, Moses Okpeku, Selaelo I. Tshilwane, Adebayo A. Adeniyi & Matthew A. Adeleke. (2023) Screening of apical membrane antigen-1 (AMA1), dense granule protein-7 (GRA7) and rhoptry protein-16 (ROP16) antigens for a potential vaccine candidate against Toxoplasma gondii for chickens. Vaccine: X 14, pages 100347.
Crossref
Xiaoyu Sang, Xiang Li, Ran Chen, Ying Feng, Ting He, Xiaohan Zhang, Saeed El-Ashram, Ebtsam Al-Olayan & Na Yang. (2023) Co-Immunization with DNA Vaccines Expressing SABP1 and SAG1 Proteins Effectively Enhanced Mice Resistance to Toxoplasma gondii Acute Infection. Vaccines 11:7, pages 1190.
Crossref
Lili Cao, Juan Liu, Songgao Cao, Panpan Zhao, Xingzhong Sun, Hang Dong, Babatunde Kazeem Bello, Yanbing Guo, Nan Wang, Nan Zhang, Ying Li, Xianhe Li & Pengtao Gong. (2023) Protective efficacy of Toxoplasma gondii bivalent MAG1 and SAG1 DNA vaccine against acute toxoplasmosis in BALB/c mice. Parasitology Research 122:3, pages 739-747.
Crossref
Tanjila Hasan, Ryo Kawanishi, Hidetaka Akita & Yoshifumi Nishikawa. (2021) Toxoplasma gondii GRA15 DNA Vaccine with a Liposomal Nanocarrier Composed of an SS-Cleavable and pH-Activated Lipid-like Material Induces Protective Immunity against Toxoplasmosis in Mice. Vaccines 10:1, pages 21.
Crossref
Fang Liu, Minmin Wu, Jie Wang, Hongyang Wen, Ran An, Haijian Cai, Li Yu, Jilong Shen, Lijian Chen & Jian Du. (2021) Protective Effect Against Toxoplasmosis in BALB/c Mice Vaccinated With Recombinant Toxoplasma gondii MIF, CDPK3, and 14-3-3 Protein Cocktail Vaccine. Frontiers in Immunology 12.
Crossref
Yu-Chao Zhu, Li-Juan Ma, Ji-Li Zhang, Jian-Fa Liu, Yong He, Ji-Ye Feng & Jia Chen. (2021) Protective Immunity Induced by TgMIC5 and TgMIC16 DNA Vaccines Against Toxoplasmosis. Frontiers in Cellular and Infection Microbiology 11.
Crossref
Narjes Yektaeian, Abdorrasoul Malekpour, Amir Atapour, Tahereh Davoodi & Gholamreza Hatam. (2021) Genetic immunization against toxoplasmosis: A review article. Microbial Pathogenesis 155, pages 104888.
Crossref
Yuchao Zhu, Yanan Xu, Lu Hong, Chunxue Zhou & Jia Chen. (2021) Immunization With a DNA Vaccine Encoding the Toxoplasma gondii’ s GRA39 Prolongs Survival and Reduce Brain Cyst Formation in a Murine Model. Frontiers in Microbiology 12.
Crossref
Yu-Chao Zhu, Yong He, Jian-Fa Liu & Jia Chen. (2020) Adjuvantic cytokine IL-33 improves the protective immunity of cocktailed DNA vaccine of ROP5 and ROP18 against toxoplasma gondii infection in mice . Parasite 27, pages 26.
Crossref
Peng Zhou, Haiying Wu, Shenghua Chen, Qinqin Bai, Xi Chen, Li Chen, Xindian Zeng, Luyao Liu & Lili Chen. (2019) MOMP and MIP DNA-loaded bacterial ghosts reduce the severity of lung lesions in mice after Chlamydia psittaci respiratory tract infection. Immunobiology 224:6, pages 739-746.
Crossref
Sharif Maraghi, Ata A. Ghadiri, Mehdi Tavalla, Saeedeh Shojaee & Rahman Abdizadeh. (2019) Evaluation of immunogenicity and protective effect of DNA vaccine encoding surface antigen1 (SAG1) of Toxoplasma gondii and TLR-5 ligand as a genetic adjuvant against acute toxoplasmosis in BALB/c mice. Biologicals 62, pages 39-49.
Crossref
Fatemeh Rezaei, Mahdi Sharif, Shahabeddin Sarvi, Seyed Hossein Hejazi, Sargis Aghayan, Abdol Sattar Pagheh, Samira Dodangeh & Ahmad Daryani. (2019) A systematic review on the role of GRA proteins of Toxoplasma gondii in host immunization. Journal of Microbiological Methods 165, pages 105696.
Crossref
Yang Zhang, Bo Shiun Lai, Mario Juhas & Yun Zhang. (2019) Toxoplasma gondii secretory proteins and their role in invasion and pathogenesis. Microbiological Research 227, pages 126293.
Crossref
Kang Liu, Hongyang Wen, Haijian Cai, Minmin Wu, Ran An, Deyong Chu, Li Yu, Jilong Shen, Lijian Chen & Jian Du. (2019) Protective Effect Against Toxoplasmosis in BALB/c Mice Vaccinated With Toxoplasma gondii Macrophage Migration Inhibitory Factor. Frontiers in Microbiology 10.
Crossref
Bin Zheng, Di Lou, Jianzu Ding, Xunhui Zhuo, Haojie Ding, Qingming Kong & Shaohong Lu. (2019) GRA24-Based DNA Vaccine Prolongs Survival in Mice Challenged With a Virulent Toxoplasma gondii Strain. Frontiers in Immunology 10.
Crossref
Masoud Foroutan, Fatemeh Ghaffarifar, Zohreh Sharifi, Abdolhosein Dalimi & Ogholniaz Jorjani. (2019) Rhoptry antigens as Toxoplasma gondii vaccine target . Clinical and Experimental Vaccine Research 8:1, pages 4.
Crossref
Xiao-Pei Xu, Wen-Ge Liu, Qian-Ming Xu, Xing-Quan Zhu & Jia Chen. (2019) Evaluation of immune protection against Toxoplasma gondii infection in mice induced by a multi-antigenic DNA vaccine containing TgGRA24, TgGRA25 and TgMIC6 . Parasite 26, pages 58.
Crossref
Gabrielle F. Watson & Paul H. Davis. (2019) Systematic review and meta-analysis of variation in Toxoplasma gondii cyst burden in the murine model. Experimental Parasitology 196, pages 55-62.
Crossref
Jia-Qi Chu, Shuai Huang, Wei Ye, Xuan-Yan Fan, Rui Huang, Shi-Cai Ye, Cai-Yuan Yu, Wei-Yun Wu, Yu Zhou, Wei Zhou, Young-Ha Lee & Juan-Hua Quan. (2018) Evaluation of Protective Immune Response Induced by a DNA Vaccine Encoding GRA8 against Acute Toxoplasmosis in a Murine Model. The Korean Journal of Parasitology 56:4, pages 325-334.
Crossref
Stephen J. Goodswen, Paul J. Kennedy & John T. Ellis. (2018) A Gene-Based Positive Selection Detection Approach to Identify Vaccine Candidates Using Toxoplasma gondii as a Test Case Protozoan Pathogen. Frontiers in Genetics 9.
Crossref
Roghiyeh Faridnia, Ahmad Daryani, Shahabeddin Sarvi, Mehdi Sharif & Hamed Kalani. (2018) Vaccination against Toxoplasma gondii using rhoptry antigens: a systematic review. Comparative Immunology, Microbiology and Infectious Diseases 59, pages 32-40.
Crossref
Jin-Lei Wang, Ting-Ting Li, Hany M Elsheikha, Kai Chen, Wei Cong, Wen-Bin Yang, Meng-Jie Bai, Si-Yang Huang & Xing-Quan Zhu. (2018) Live Attenuated Pru:Δcdpk2 Strain of Toxoplasma gondii Protects Against Acute, Chronic, and Congenital Toxoplasmosis. The Journal of Infectious Diseases 218:5, pages 768-777.
Crossref
Yajun Chen, Miao Yu, J.A. Hemandez, Jiexi Li, Zi-Guo Yuan & Haikuo Yan. (2018) Immuno-efficacy of DNA vaccines encoding PLP1 and ROP18 against experimental Toxoplasma gondii infection in mice. Experimental Parasitology 188, pages 73-78.
Crossref
Masoud ForoutanLeila ZakiFatemeh Ghaffarifar. (2018) Recent progress in microneme-based vaccines development against Toxoplasma gondii . Clinical and Experimental Vaccine Research 7:2, pages 93.
Crossref
Wen-Bin Yang, Dong-Hui Zhou, Yang Zou, Kai Chen, Qing Liu, Jin-Lei Wang, Xing-Quan Zhu & Guang-Hui Zhao. (2017) Vaccination with a DNA vaccine encoding Toxoplasma gondii ROP54 induces protective immunity against toxoplasmosis in mice. Acta Tropica 176, pages 427-432.
Crossref
Wei-Ning Zhu, Jin-Lei Wang, Kai Chen, Dong-Mei Yue, Xiao-Xuan Zhang, Si-Yang Huang & Xing-Quan Zhu. (2017) Evaluation of protective immunity induced by DNA vaccination with genes encoding Toxoplasma gondii GRA17 and GRA23 against acute toxoplasmosis in mice. Experimental Parasitology 179, pages 20-27.
Crossref
Ling-Ying Hu, Nian-Zhang Zhang, Fu-Kai Zhang, Meng Wang, Qi Gao, Jin-Lei Wang & Xing-Quan Zhu. (2017) Resistance to Chronic Toxoplasma gondii Infection Induced by a DNA Vaccine Expressing GRA16 . BioMed Research International 2017, pages 1-6.
Crossref
Pengtao Gong, Lili Cao, Yanbing Guo, Hang Dong, Shuxian Yuan, Xinhua Yao, Wenzhi Ren, Lin Yao, Zhilin Xu, Qiang Sun & Xichen Zhang. (2016) Toxoplasma gondii: Protective immunity induced by a DNA vaccine expressing GRA1 and MIC3 against toxoplasmosis in BALB/c mice. Experimental Parasitology 166, pages 131-136.
Crossref
Jia Chen, Zhong-Yuan Li, Eskild Petersen, Wen-Ge Liu & Xing-Quan Zhu. (2016) Co-administration of interleukins 7 and 15 with DNA vaccine improves protective immunity against Toxoplasma gondii. Experimental Parasitology 162, pages 18-23.
Crossref
Marcin M. Grzybowski, Bożena Dziadek, Justyna M. Gatkowska, Katarzyna Dzitko & Henryka Długońska. (2015) Towards vaccine against toxoplasmosis: evaluation of the immunogenic and protective activity of recombinant ROP5 and ROP18 Toxoplasma gondii proteins. Parasitology Research 114:12, pages 4553-4563.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.