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Point of care diagnostics for sexually transmitted infections: perspectives and advances

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Barbara Van Der Pol & Charlotte A. Gaydos. (2021) A profile of the binx health io® molecular point-of-care test for chlamydia and gonorrhea in women and men. Expert Review of Molecular Diagnostics 21:9, pages 861-868.
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Charlotte A. Gaydos & Johan H. Melendez. (2020) Point-by-Point Progress: Gonorrhea Point of Care Tests. Expert Review of Molecular Diagnostics 20:8, pages 803-813.
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Leshan Xiu, Chi Zhang, Yamei Li, Feng Wang & Junping Peng. (2019) Simultaneous detection of eleven sexually transmitted agents using multiplexed PCR coupled with MALDI-TOF analysis. Infection and Drug Resistance 12, pages 2671-2682.
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Luc Bissonnette & Michel G. Bergeron. (2017) Portable devices and mobile instruments for infectious diseases point-of-care testing. Expert Review of Molecular Diagnostics 17:5, pages 471-494.
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Chelsea P. Roberts & Jeffrey D. Klausner. (2016) Global challenges in human immunodeficiency virus and syphilis coinfection among men who have sex with men. Expert Review of Anti-infective Therapy 14:11, pages 1037-1046.
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Nitika Pant Pai & Jana Daher. (2015) Multiplexed testing for HIV and related bacterial and viral co-infections at the point-of-care: quo vadis?. Expert Review of Molecular Diagnostics 15:4, pages 463-469.
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Paul O. Verhoeven, Sylvie Gonzalo, Meriam Memmi, Bruno Pozzetto & Florence Grattard. 2024. Diagnostic Molecular Pathology. Diagnostic Molecular Pathology 147 158 .
Ashleigh N. Riegler, Natalie Larsen & Megan H. Amerson-Brown. (2023) Point-of-Care Testing for Sexually Transmitted Infections. Clinics in Laboratory Medicine 43:2, pages 189-207.
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Elise Smith, Lindi Masson, Jo-Ann S. Passmore & Edina Sinanovic. (2023) Cost-effectiveness analysis of different screening and diagnostic strategies for sexually transmitted infections and bacterial vaginosis in women attending primary health care facilities in Cape Town. Frontiers in Public Health 11.
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Georg Daeschlein, Sabine Westphal, Julian Schäfer, Christos C. Zouboulis & Kathrin Schlatterer. (2022) Sexuell übertragbare Infektionen (STDs) und Prävention. Aktuelle Dermatologie 48:08/09, pages 392-399.
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S. Vargas, G. Calvo, J. Qquellon, F. Vasquez, K. Blondeel, R. Ballard & I. Toskin. (2022) Point-of-care testing for sexually transmitted infections in low-resource settings. Clinical Microbiology and Infection 28:7, pages 946-951.
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C Shangase, N Mabaso, R Singh, P Tinarwo & N Abbai. (2022) Differences in the microbial profile in South African pregnant women with Trichomonas vaginalis and Chlamydia trachomatis infections using a real-time polymerase chain reaction approach . The Journal of Medical Laboratory Science and Technology of South Africa 4:1, pages 20-28.
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Angela Karellis, Faheel Naeem, Suma Nair, Sneha D Mallya, Jean-Pierre Routy, Jacqueline Gahagan, Cédric P Yansouni, John Kim & Nitika Pant Pai. (2022) Multiplexed rapid technologies for sexually transmitted infections: a systematic review. The Lancet Microbe 3:4, pages e303-e315.
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Agata Pacho, Emma M. Harding-Esch, Emma G. Heming De-Allie, Laura Phillips, Martina Furegato, S. Tariq Sadiq & Sebastian S. Fuller. (2022) Facilitators and barriers for clinical implementation of a 30-minute point-of-care test for Neisseria gonorrhoeae and Chlamydia trachomatis into clinical care: A qualitative study within sexual health services in England. PLOS ONE 17:3, pages e0265173.
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Kuangwen Hsieh, Johan H. Melendez, Charlotte A. Gaydos & Tza-Huei Wang. (2022) Bridging the gap between development of point-of-care nucleic acid testing and patient care for sexually transmitted infections. Lab on a Chip 22:3, pages 476-511.
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Andre J. W. Loh, Ee Lynn Ting, Teodora E. Wi, Philippe Mayaud, Eric P. F. Chow, Nancy Santesso, Jane Falconer, Richard Ofori-Asenso & Jason J. Ong. (2022) The Diagnostic Accuracy of Syndromic Management for Genital Ulcer Disease: A Systematic Review and Meta-Analysis. Frontiers in Medicine 8.
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Hayder A. Abdulbari. 2022. Nanotechnology for Hematology, Blood Transfusion, and Artificial Blood. Nanotechnology for Hematology, Blood Transfusion, and Artificial Blood 265 283 .
Charlotte A. Gaydos, Yukari C. Manabe & Johan H. Melendez. (2021) A Narrative Review of Where We Are With Point-of-Care Sexually Transmitted Infection Testing in the United States. Sexually Transmitted Diseases 48:8S, pages S71-S77.
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Olga P. M. Saweri, Neha Batura, Rabiah Al Adawiyah, Louise M. Causer, William S. Pomat, Andrew J. Vallely & Virginia Wiseman. (2021) Economic evaluation of point-of-care testing and treatment for sexually transmitted and genital infections in pregnancy in low- and middle-income countries: A systematic review. PLOS ONE 16:6, pages e0253135.
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Peuli Nath, Md Alamgir Kabir, Somaiyeh Khoubafarin Doust & Aniruddha Ray. (2021) Diagnosis of Herpes Simplex Virus: Laboratory and Point-of-Care Techniques. Infectious Disease Reports 13:2, pages 518-539.
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Alexander Y. Trick, Johan H. MelendezFan-En Chen, Liben Chen, Annet Onzia, Aidah ZaweddeEdith Nakku-JolobaPeter Kyambadde, Emmanuel Mande, Joshua MatovuMaxine Atuheirwe, Richard Kwizera, Elizabeth A. Gilliams, Yu-Hsiang Hsieh, Charlotte A. Gaydos, Yukari C. ManabeMatthew M. Hamill & Tza-Huei Wang. (2021) A portable magnetofluidic platform for detecting sexually transmitted infections and antimicrobial susceptibility. Science Translational Medicine 13:593.
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Sheldon R Morris, Claire C Bristow, Michael R Wierzbicki, Mark Sarno, Lenore Asbel, Audrey French, Charlotte A Gaydos, Lydie Hazan, Leandro Mena, Purnima Madhivanan, Susan Philip, Saara Schwartz, Constance Brown, David Styers, Toni Waymer & Jeffrey D Klausner. (2021) Performance of a single-use, rapid, point-of-care PCR device for the detection of Neisseria gonorrhoeae, Chlamydia trachomatis, and Trichomonas vaginalis: a cross-sectional study. The Lancet Infectious Diseases 21:5, pages 668-676.
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Jieun Jeong, Jae-Seok Kim, Junghyeon Lee, Yu Seo, Eugene Yi & Kristine Kim. (2021) Neisseria gonorrhoeae Multivalent Maxibody with a Broad Spectrum of Strain Specificity and Sensitivity for Gonorrhea Diagnosis. Biomolecules 11:3, pages 484.
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Hiam Chemaitelly, Alzahraa Majed, Farah Abu-Hijleh, Karel Blondeel, Thabo Christopher Matsaseng, James Kiarie, Igor Toskin & Laith J Abu-Raddad. (2021) Global epidemiology of Neisseria gonorrhoeae in infertile populations: systematic review, meta-analysis and metaregression . Sexually Transmitted Infections 97:2, pages 157-169.
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Vineeta Sharma, Subash Chandra Sonkar, Pallavi Singhal, Anoop Kumar, Rakesh Kumar Singh, V. G. Ramachandran, Roopa Hariprasad, Daman Saluja & Mausumi Bharadwaj. (2021) Functional impact of allelic variations/haplotypes of TNF-α on reproductive tract infections in Indian women. Scientific Reports 11:1.
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Suzanna C. Francis, Arun Parajuli, Otilia Mardh, Jane Falconer, Aura Andreasen & Emma Harding-Esch. (2020) Technologies, strategies and approaches for testing populations at risk of sexually transmitted infections: a systematic review protocol to inform prevention and control in EU/EEA countries. Systematic Reviews 9:1.
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Feliciana Lage Marinho & Danielle Zauli. (2020) Cross-sectional study of patients tested for STIs using molecular methods in Brazil. Sexually Transmitted Infections 96:7, pages 493-493.
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Tian-Ao Xie, Ye-Ling Liu, Rui-Chun Meng, Xiao-Shan Liu, Ke-Ying Fang, Shu-Ting Deng, Shu-Jin Fan, Chu-Mao Chen, Qin-Rong Lin, Zhi-Jian He, Zhen-Xing Li, Shi Ouyang, Guo-Dong Zhu, Tian-Xing Ji, Yong Xia, Zhi-Yong Pan & Xu-Guang Guo. (2020) Evaluation of the Diagnostic Efficacy of Xpert CT/NG for Chlamydia trachomatis and Neisseria gonorrhoeae. BioMed Research International 2020, pages 1-16.
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Cecilia Ferreyra, Jennifer Osborn, Francis Moussy, Emilie Alirol, Monica Lahra, David Whiley, William Shafer, Magnus Unemo, Jeffrey Klausner, Cassandra Kelly Cirino & Teodora Wi. (2020) Developing target product profiles for Neisseria gonorrhoeae diagnostics in the context of antimicrobial resistance: An expert consensus. PLOS ONE 15:9, pages e0237424.
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Brenda J. Korte, Anne Rompalo, Yukari C. Manabe & Charlotte A. Gaydos. (2020) Overcoming Challenges With the Adoption of Point-of-Care Testing. Point of Care: The Journal of Near-Patient Testing & Technology 19:3, pages 77-83.
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Andreas Hahn, Andreas Podbielski, Thomas Meyer, Andreas Erich Zautner, Ulrike Loderstädt, Norbert Georg Schwarz, Andreas Krüger, Daniel Cadar & Hagen Frickmann. (2020) On detection thresholds–a review on diagnostic approaches in the infectious disease laboratory and the interpretation of their results. Acta Tropica 205, pages 105377.
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Minttu M Rönn, Nicolas A Menzies, Thomas L Gift, Harrell W Chesson, Tom A Trikalinos, Meghan Bellerose, Yelena Malyuta, Andrés Berruti, Charlotte A Gaydos, Katherine K Hsu & Joshua A Salomon. (2020) Potential for Point-of-Care Tests to Reduce Chlamydia-associated Burden in the United States: A Mathematical Modeling Analysis. Clinical Infectious Diseases 70:9, pages 1816-1823.
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Jenell Stewart, Elizabeth Bukusi, Connie Celum, Sinead Delany-Moretlwe & Jared M. Baeten. (2020) Sexually transmitted infections among African women: an opportunity for combination sexually transmitted infection/HIV prevention. AIDS 34:5, pages 651-658.
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Glen T Hansen. (2020) Point-of-Care Testing in Microbiology: A Mechanism for Improving Patient Outcomes. Clinical Chemistry 66:1, pages 124-137.
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Jesse Gettinger, Nicholas Van Wagoner, Brice Daniels, Alexander Boutwell & Barbara Van Der Pol. (2020) Patients Are Willing to Wait for Rapid Sexually Transmitted Infection Results in a University Student Health Clinic. Sexually Transmitted Diseases 47:1, pages 67-69.
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Fabio Lisi, Joshua R. Peterson & J. Justin Gooding. (2020) The application of personal glucose meters as universal point-of-care diagnostic tools. Biosensors and Bioelectronics 148, pages 111835.
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Adriane Skaletz-Rorowski, Marcus Mau & Norbert H. Brockmeyer. (2019) Schnelltests in der STI-Diagnostik. Uro-News 23:12, pages 24-27.
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Faye M. Walker & Kuangwen Hsieh. (2019) Advances in Directly Amplifying Nucleic Acids from Complex Samples. Biosensors 9:4, pages 117.
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Hui Chen, Zhao Li, Lingzhi Zhang, Philippe Sawaya, Jianbo Shi & Ping Wang. (2019) Quantitation of Femtomolar‐Level Protein Biomarkers Using a Simple Microbubbling Digital Assay and Bright‐Field Smartphone Imaging. Angewandte Chemie International Edition 58:39, pages 13922-13928.
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Hui Chen, Zhao Li, Lingzhi Zhang, Philippe Sawaya, Jianbo Shi & Ping Wang. (2019) Quantitation of Femtomolar‐Level Protein Biomarkers Using a Simple Microbubbling Digital Assay and Bright‐Field Smartphone Imaging. Angewandte Chemie 131:39, pages 14060-14066.
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Nathan E. Ogden, Martin Kurnik, Claudio Parolo & Kevin W. Plaxco. (2019) An electrochemical scaffold sensor for rapid syphilis diagnosis. The Analyst 144:17, pages 5277-5283.
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Teodora EC Wi, Francis J Ndowa, Cecilia Ferreyra, Cassandra Kelly‐Cirino, Melanie M Taylor, Igor Toskin, James Kiarie, Nancy Santesso & Magnus Unemo. (2019) Diagnosing sexually transmitted infections in resource‐constrained settings: challenges and ways forward. Journal of the International AIDS Society 22:S6.
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Meena S. Ramchandani & Matthew R. Golden. (2019) Confronting Rising STIs in the Era of PrEP and Treatment as Prevention. Current HIV/AIDS Reports 16:3, pages 244-256.
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Vicky Cuylaerts, Irith De Baetselier, Claude M. Muvunyi, Lambert Mwambarange, Hilde Smet, John Rusine, Viateur Musengamana, Janneke Van de Wijgert & Tania Crucitti. (2019) Implementation and evaluation of the Presto combined qualitative real-time assay for Chlamydia trachomatis and Neisseria gonorrhoeae in Rwanda. African Journal of Laboratory Medicine 8:1.
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Sebastian S. Fuller, Agata Pacho, Claire E. Broad, Achyuta V. Nori, Emma M. Harding-Esch & Syed Tariq Sadiq. (2019) “It’s not a time spent issue, it’s a ‘what have you spent your time doing?’ issue…” A qualitative study of UK patient opinions and expectations for implementation of Point of Care Tests for sexually transmitted infections and antimicrobial resistance. PLOS ONE 14:4, pages e0215380.
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Hanbi Kim, Doo-Ryeon Chung & Minhee Kang. (2019) A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays. The Analyst 144:8, pages 2460-2466.
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Catherine L. Hall, Mark A. Harrison, Marcus J. Pond, Christine Chow, Emma M. Harding-Esch & S. Tariq Sadiq. (2019) Genotypic determinants of fluoroquinolone and macrolide resistance in Neisseria gonorrhoeae. Sexual Health 16:5, pages 479.
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Margot Karlikow & Keith Pardee. 2019. Paper-based Diagnostics. Paper-based Diagnostics 171 201 .
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Barbara Van Der Pol. 2018. Diagnostics to Pathogenomics of Sexually Transmitted Infections. Diagnostics to Pathogenomics of Sexually Transmitted Infections 341 356 .
Adriane Skaletz-Rorowski, Marcus Mau & Norbert H. Brockmeyer. (2018) Schnelltests in der STI-Diagnostik. hautnah dermatologie 34:6, pages 30-34.
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Claire C. Bristow, Chelsea Shannon, Sasha Herbst de Cortina & Jeffrey D. Klausner. (2018) Use of Oral Fluid With a Rapid Treponemal Test for Syphilis Evaluation. Sexually Transmitted Diseases 45:9, pages e65-e67.
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Peter H. Kilmarx, Elizabeth Gonese, David A. Lewis, Z. Mike Chirenje, Beth A. Tippett Barr, Ahmed S. Latif, Lovemore Gwanzura, H. Hunter Handsfield, Anna Machiha, Owen Mugurungi & Cornelius A. Rietmeijer. (2018) HIV infection in patients with sexually transmitted infections in Zimbabwe – Results from the Zimbabwe STI etiology study. PLOS ONE 13:6, pages e0198683.
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Dong Jin Shin, Mitra Lewis, Yu-Hsiang Hsieh, Noha Atef Rahmoun, Charlotte A. Gaydos, Tza-Huei Wang & Richard Rothman. (2018) Healthcare Worker Feedback on a Prototype Smartphone-Based Point-of-Care Test Platform for Use in Episodic Care. Point of Care: The Journal of Near-Patient Testing & Technology 17:2, pages 63-65.
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