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Treatment failure in leishmaniasis: drug-resistance or another (epi-) phenotype?

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Juliana Q. Reimão, Débora P. Pita Pedro & Adriano C. Coelho. (2020) The preclinical discovery and development of oral miltefosine for the treatment of visceral leishmaniasis: a case history. Expert Opinion on Drug Discovery 15:6, pages 647-658.
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Alexis Mendoza-León, María Luisa Serrano G.Alicia Ponte-Sucre. (2023) Challenges in drug discovery and description targeting Leishmania spp.: enzymes, structural proteins, and transporters. Frontiers in Tropical Diseases 4.
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Varol Tunalı, Mehmet Harman, İbrahim Çavuş, Orçun Zorbozan, Ahmet Özbilgin & Nevin Turgay. (2022) Investigation of <i>in vitro</i> Efficacy of Miltefosine on Chronic Cutaneous Leishmaniasis. Turkish Journal of Parasitology 46:2, pages 97-101.
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Ana Perea-Martínez, Raquel García-Hernández, José Ignacio Manzano & Francisco Gamarro. (2022) Transcriptomic Analysis in Human Macrophages Infected with Therapeutic Failure Clinical Isolates of Leishmania infantum . ACS Infectious Diseases 8:4, pages 800-810.
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Luiza O. R. Pereira, Cíntia S. Sousa, Hellen C. P. Ramos, Eduardo C. Torres-Santos, Liliane S. Pinheiro, Marcelo R. Alves, Patricia Cuervo, Gustavo A. Sierra Romero, Mariana C. Boité, Renato Porrozzi & Elisa Cupolillo. (2021) Insights from Leishmania (Viannia) guyanensis in vitro behavior and intercellular communication. Parasites & Vectors 14:1.
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Nargis Shaheen, Chaitenya Verma, Thalia Pacheco-Fernandez, Greta Volpedo, Aneeqa Hamid, Ismail Zeb, Syed Aizaz Ali Shah, Shah Fahad, Attiya Iqbal, Asma Ashraf, Amjad Khan, Misbah Gul, Muhammad Ilyas Khan, Huma Fatima, Muhammad Afzal, Abhay R Satoskar & Naveeda Akhter Qureshi. (2021) Molecular characterization and genetic diversity of cutaneous leishmaniasis from North Eastern Pakistan. Acta Tropica 221, pages 105964.
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Joachim Kloehn, Berin A. Boughton, Eleanor C. Saunders, Sean O’Callaghan, Katrina J. Binger & Malcolm J. McConville. (2021) Identification of Metabolically Quiescent Leishmania mexicana Parasites in Peripheral and Cured Dermal Granulomas Using Stable Isotope Tracing Imaging Mass Spectrometry . mBio 12:2.
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Somayeh Bahrami, Moslem Safari, Mohammad Hossein Razi Jalali, Masoud Ghorbanpoor, Mohammad Reza Tabandeh & Annahita Rezaie. (2021) The potential therapeutic effect of adipose-derived mesenchymal stem cells in the treatment of cutaneous leishmaniasis caused by L. major in BALB/c mice. Experimental Parasitology 222, pages 108063.
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Marcela Parra-MuñozSamanda AponteClemencia Ovalle-BrachoCarlos H. Saavedra & María C. Echeverry. (2021) Detection of Leishmania RNA Virus in Clinical Samples from Cutaneous Leishmaniasis Patients Varies according to the Type of Sample. The American Journal of Tropical Medicine and Hygiene 104:1, pages 233-239.
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Juliana G Pinto, Luciana MC Marcolino & Juliana Ferreira-Strixino. (2021) Photodynamic activity of Photogem ® in Leishmania promastigotes and infected macrophages . Future Microbiology 16:2, pages 95-106.
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Mohsen Abtahi, Gilda Eslami, Serena Cavallero, Mahmood Vakili, Saeedeh Sadat Hosseini, Salman Ahmadian, Mohammad Javad Boozhmehrani & Ali Khamesipour. (2020) Relationship of Leishmania RNA Virus (LRV) and treatment failure in clinical isolates of Leishmania major. BMC Research Notes 13:1.
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Sarah Hendrickx, Lieselotte Van Bockstal, Dimitri Bulté, Annelies Mondelaers, Hamide Aslan, Luis Rivas, Louis Maes & Guy Caljon. (2020) Phenotypic adaptations of Leishmania donovani to recurrent miltefosine exposure and impact on sand fly infection. Parasites & Vectors 13:1.
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Pamela Martínez-Orellana, Marta Baxarias, Liam Good & Laia Solano-Gallego. (2020) The Effects of Polyhexamethylene Biguanide (PHMB) and TLR Agonists Alone or as Polyplex Nanoparticles against Leishmania infantum Promastigotes and Amastigotes. Veterinary Sciences 7:4, pages 179.
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M. Van den Kerkhof, D. Mabille, S. Hendrickx, P. Leprohon, C. E. Mowbray, S. Braillard, M. Ouellette, L. Maes & G. Caljon. (2020) Antileishmanial Aminopyrazoles: Studies into Mechanisms and Stability of Experimental Drug Resistance. Antimicrobial Agents and Chemotherapy 64:9.
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Rohit Sharma, Paulo S. Silveira-Mattos, Vinicius C. Ferreira, Francys A. Rangel, Laíse B. Oliveira, Fabiana S. Celes, Sayonara M. Viana, Mary E. Wilson & Camila I. de Oliveira. (2020) Generation and Characterization of a Dual-Reporter Transgenic Leishmania braziliensis Line Expressing eGFP and Luciferase. Frontiers in Cellular and Infection Microbiology 9.
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