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Expert Review of Anti-infective Therapy Volume 3, 2005 - Issue 6
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Atovaquone/proguanil for the prophylaxis and treatment of malaria

Samir N Patel Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada. [email protected]
&
Kevin C Kain McLaughlin-Rotman Center for Global Health, McLaughlin Center for Molecular Medicine, University of Toronto, Center for Travel and Tropical Medicine, Toronto General Hospital, 200 Elizabeth Street, EN 13–214, Toronto, ON, Canada. [email protected]
Pages 849-861 | Published online: 10 Jan 2014

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Emmanuel Bottieau, Marc Vekemans & Alfons Van Gompel. (2011) Therapy of vector-borne protozoan infections in nonendemic settings. Expert Review of Anti-infective Therapy 9:5, pages 583-608.
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Francesco Castelli, Susanna Capone, Barbara Pedruzzi & Alberto Matteelli. (2007) Antimicrobial prevention and therapy for travelers’ infection. Expert Review of Anti-infective Therapy 5:6, pages 1031-1048.
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Articles from other publishers (21)

Faizal HermantoAnas SubarnasAfifah B. SutjiatmoAfiat Berbudi. (2022) Apigenin: Review of Mechanisms of Action as Antimalarial. Research Journal of Pharmacy and Technology, pages 458-466.
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Li Na Zhao, Mikael Björklund, Matias J. Caldez, Jie Zheng & Philipp Kaldis. (2021) Therapeutic targeting of the mitochondrial one-carbon pathway: perspectives, pitfalls, and potential. Oncogene 40:13, pages 2339-2354.
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María Valente, Antonio E. Vidal & Dolores González-Pacanowska. (2019) Targeting Kinetoplastid and Apicomplexan Thymidylate Biosynthesis as an Antiprotozoal Strategy. Current Medicinal Chemistry 26:22, pages 4262-4279.
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Bruno Pradines. 2017. Antimicrobial Drug Resistance. Antimicrobial Drug Resistance 1245 1275 .
Domagoj Dinter, Goran Gajski, Ana-Marija Domijan & Vera Garaj-Vrhovac. (2015) Cytogenetic and oxidative status of human lymphocytes after exposure to clinically relevant concentrations of antimalarial drugs atovaquone and proguanil hydrochloride in vitro. Fundamental & Clinical Pharmacology 29:6, pages 575-585.
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Oscar Ramirez, Laura B. Motta-Mena, Amanda Cordova & Kristine M. Garza. (2014) A Small Library of Synthetic Di-Substituted 1, 4-Naphthoquinones Induces ROS-Mediated Cell Death in Murine Fibroblasts. PLoS ONE 9:9, pages e106828.
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Frank Seeber, Jean E. Feagin & Marilyn Parsons. 2014. Toxoplasma Gondii. Toxoplasma Gondii 297 350 .
Domagoj Dinter, Goran Gajski & Vera Garaj‐Vrhovac. (2011) An alkaline comet assay study on the antimalarial drug atovaquone in human peripheral blood lymphocytes: a study based on clinically relevant concentrations. Journal of Applied Toxicology 33:1, pages 56-62.
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Nathalie Wurtz, Aurélie Pascual, Adeline Marin-Jauffre, Housem Bouchiba, Nicolas Benoit, Marc Desbordes, Maryse Martelloni, Vincent Pommier de Santi, Georges Richa, Nicolas Taudon, Bruno Pradines & Sébastien Briolant. (2012) Early treatment failure during treatment of Plasmodium falciparum malaria with atovaquone-proguanil in the Republic of Ivory Coast. Malaria Journal 11:1.
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Cyrille Y. Botté, Faustine Dubar, Geoffrey I. McFadden, Eric Maréchal & Christophe Biot. (2011) Plasmodium falciparum Apicoplast Drugs: Targets or Off-Targets?. Chemical Reviews 112:3, pages 1269-1283.
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Javier Calvo, José Luis Lavandera, Maite Agüeros & Juan M. Irache. (2011) Cyclodextrin/poly(anhydride) nanoparticles as drug carriers for the oral delivery of atovaquone. Biomedical Microdevices 13:6, pages 1015-1025.
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L. Monzote, W. Stamberg, A. Patel, T. Rosenau, L. Maes, P. Cos & L. Gille. (2011) Synthetic Chromanol Derivatives and Their Interaction with Complex III in Mitochondria from Bovine, Yeast, and Leishmania. Chemical Research in Toxicology 24:10, pages 1678-1685.
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Gundula Min-Oo & Philippe Gros. (2011) Genetic analysis in mice identifies cysteamine as a novel partner for artemisinin in the treatment of malaria. Mammalian Genome 22:7-8, pages 486-494.
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Goran Gajski, Domagoj Dinter & Vera Garaj-Vrhovac. (2010) In vitro effect of the antimalarial drug proguanil hydrochloride on viability and DNA damage in human peripheral blood lymphocytes. Environmental Toxicology and Pharmacology 30:3, pages 257-263.
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Tien L Huang, Jean Jacques Vanden Eynde, Annie Mayence, Isaac O Donkor, Shabana I Khan & Babu L Tekwani. (2006) Anti-plasmodial and anti-leishmanial activity of conformationally restricted pentamidine congeners. Journal of Pharmacy and Pharmacology 58:8, pages 1033-1042.
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Shon A Remich, Walter Otieno, Mark E Polhemus, Bernhards Ogutu & Douglas S Walsh. (2008) Bullous erythema multiforme after treatment with Malarone ® , a combination antimalarial composed of atovaquone and proguanil hydrochloride . Tropical Doctor 38:3, pages 190-191.
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Martin Schlitzer. (2008) Antimalarial Drugs – What is in Use and What is in the Pipeline. Archiv der Pharmazie 341:3, pages 149-163.
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Martin Schlitzer. (2007) Malaria Chemotherapeutics Part I: History of Antimalarial Drug Development, Currently Used Therapeutics, and Drugs in Clinical Development. ChemMedChem 2:7, pages 944-986.
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J.E. Feagin & M. Parsons. 2007. Toxoplasma Gondii. Toxoplasma Gondii 207 244 .
Beatriz C. Jiménez, Miriam Navarro, Helena Huerga, Eva López‐Román, Alfonso Mendoza & Rogelio López‐Vélez. (2006) Tertian Malaria ( Plasmodium vivax and Plasmodium ovale ) in Two Travelers Despite Atovaquone–Proguanil Prophylaxis . Journal of Travel Medicine 13:6, pages 373-375.
Crossref
Alexis Nzila. (2006) Inhibitors of de novo folate enzymes in Plasmodium falciparum. Drug Discovery Today 11:19-20, pages 939-944.
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