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Review

Therapeutic approaches for prion disorders

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Pages 613-630 | Published online: 10 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Soshi Kanemoto. (2015) Targeting the endoplasmic reticulum in prion disease treatment: breakthroughs and challenges. Research and Reports in Biochemistry 5, pages 31-38.
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Nives Škrlj & Marko Dolinar. (2014) New engineered antibodies against prions. Bioengineered 5:1, pages 10-14.
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Aadilah Omar, Katarina Jovanovic, Bianca Da Costa Dias, Danielle Gonsalves, Kiashanee Moodley, Robert Caveney, Vusi Mbazima & Stefan FT Weiss. (2011) Patented biological approaches for the therapeutic modulation of the 37 kDa/67 kDa laminin receptor. Expert Opinion on Therapeutic Patents 21:1, pages 35-53.
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Rajna Dimitrijević, Ivana Čadež, Milica Keckarević-Marković, Dušan Keckarević, Miljana Kecmanović, Valerija Dobričić, Dušanka Savić-Pavićević, Goran Brajušković & Stanka Romac. (2010) Polymorphisms of the Prion Protein Gene (PRNP) in a Serbian Population. International Journal of Neuroscience 120:7, pages 496-501.
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Federico Benetti & Giuseppe Legname. (2009) De novo mammalian prion synthesis. Prion 3:4, pages 213-219.
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Suehiro Sakaguchi, Daisuke Ishibashi & Haruo Matsuda. (2009) Antibody-based immunotherapeutic attempts in experimental animal models of prion diseases. Expert Opinion on Therapeutic Patents 19:7, pages 907-917.
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Suehiro Sakaguchi. (2008) Recent developments in therapeutics for prion diseases. Expert Opinion on Therapeutic Patents 18:1, pages 35-59.
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Chantal Zuber, Gerda Mitteregger, Claudia Pace, Inga Zerr, Hans A. Kretzschmar & Stefan Weiss. (2007) Anti-LRP/LR Antibody W3 Hampers Peripheral PrPSc Propagation in Scrapie Infected Mice. Prion 1:3, pages 207-212.
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Articles from other publishers (34)

Ermias D. Belay & Brian S. Appleby. 2020. Viral Infections of Humans. Viral Infections of Humans 1 49 .
Inga Zerr. 2020. Klinische Neurologie. Klinische Neurologie 1273 1282 .
I. Zerr. (2019) S1-Leitlinie: Creutzfeldt-Jakob-KrankheitS1 guideline: Creutzfeldt–Jakob syndrome. DGNeurologie 2:3, pages 179-185.
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N. G. Dudchenko & E. E. Vasenina. (2019) Rapidly progressive dementia. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 119:9, pages 78.
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Inga Zerr. 2018. Klinische Neurologie. Klinische Neurologie 1 10 .
Thibaut Imberdis, Adeline Ayrolles-Torro, Alysson Duarte Rodrigues, Joan Torrent, Maria Teresa Alvarez-Martinez, Gabor G. Kovacs, Jean-Michel Verdier, Mike Robitzer & Véronique Perrier. (2016) A Fluorescent Oligothiophene-Bis-Triazine ligand interacts with PrP fibrils and detects SDS-resistant oligomers in human prion diseases. Molecular Neurodegeneration 11:1.
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Daniela Sarnataro, Anna Pepe, Gennaro Altamura, Imma De Simone, Ada Pesapane, Lucio Nitsch, Nunzia Montuori, Antonio Lavecchia & Chiara Zurzolo. (2016) The 37/67kDa laminin receptor (LR) inhibitor, NSC47924, affects 37/67kDa LR cell surface localization and interaction with the cellular prion protein. Scientific Reports 6:1.
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Inga Zerr. 2016. Neurologie. Neurologie 551 557 .
Salvatore Bongarzone, Matteo Staderini & Maria Laura Bolognesi. (2014) Multitarget ligands and theranostics: sharpening the medicinal chemistry sword against prion diseases. Future Medicinal Chemistry 6:9, pages 1017-1029.
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Ermias D. Belay & Jason C. Bartz. 2014. Viral Infections of Humans. Viral Infections of Humans 1165 1186 .
Liang Huang, Xiaomin Su & Howard Federoff. (2013) Single-Chain Fragment Variable Passive Immunotherapies for Neurodegenerative Diseases. International Journal of Molecular Sciences 14:9, pages 19109-19127.
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Nives Škrlj, Gorazd Drevenšek, Samo Hudoklin, Rok Romih, Vladka Čurin Šerbec & Marko Dolinar. (2012) Recombinant Single-Chain Antibody with the Trojan Peptide Penetratin Positioned in the Linker Region Enables Cargo Transfer Across the Blood–Brain Barrier. Applied Biochemistry and Biotechnology 169:1, pages 159-169.
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Takafumi SUNAGA, Namgil OH, Kenji HOSOYA, Satoshi TAKAGI & Masahiro OKUMURA. (2012) Inhibitory Effects of Pentosan Polysulfate Sodium on MAP-Kinase Pathway and NF-κB Nuclear Translocation in Canine Chondrocytes <i>In Vitro</i>. Journal of Veterinary Medical Science 74:6, pages 707-711.
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Amjed Hussain, Masroor E Babar, Muhammad Imran, Ikram U Haq & Muhammad M Javed. (2011) Detection of Four Novel Polymorphisms in PrP gene of Pakistani sheep (Damani and Hashtnagri) and goats (Kamori and Local Hairy) breeds. Virology Journal 8:1.
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Adeline Ayrolles-Torro, Thibaut Imberdis, Joan Torrent, Karine Toupet, Ilia V. Baskakov, Guillaume Poncet-Montange, Catherine Grégoire, Françoise Roquet-Baneres, Sylvain Lehmann, Didier Rognan, Martine Pugnière, Jean-Michel Verdier & Véronique Perrier. (2011) Oligomeric-Induced Activity by Thienyl Pyrimidine Compounds Traps Prion Infectivity. The Journal of Neuroscience 31:42, pages 14882-14892.
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Markus Geissen, Fabienne Leidel, Martin Eiden, Thomas Hirschberger, Christine Fast, Uwe Bertsch, Paul Tavan, Armin Giese, Hans Kretzschmar, Hermann M. Schatzl & Martin H. Groschup. (2011) From High-Throughput Cell Culture Screening to Mouse Model: Identification of New Inhibitor Classes against Prion Disease. ChemMedChem 6:10, pages 1928-1937.
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Nives Škrlj, Tanja Vranac, Mara Popović, Vladka Čurin Šerbec & Marko Dolinar. (2011) Specific Binding of the Pathogenic Prion Isoform: Development and Characterization of a Humanized Single-Chain Variable Antibody Fragment. PLoS ONE 6:1, pages e15783.
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E. Schmutzhard, R. Kaiser, U. Meyding-Lamadé, G. Arendt, T. Nolting, M. Maschke & I. Zerr. 2012. Klinische Neurologie. Klinische Neurologie 723 791 .
Dominika Kolodziejczak, Bianca Da Costa Dias, Chantal Zuber, Katarina Jovanovic, Aadilah Omar, Julia Beck, Karen Vana, Vusi Mbazima, Juergen Richt, Bertram Brenig & Stefan F.T. Weiss. (2010) Prion Interaction with the 37-kDa/67-kDa Laminin Receptor on Enterocytes as a Cellular Model for Intestinal Uptake of Prions. Journal of Molecular Biology 402:2, pages 293-300.
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Matthias Schmitz, Markus Schlomm, Badrul Hasan, Michael Beekes, Eva Mitrova, Carsten Korth, Andreas Breil, Julie Carimalo, Joanna Gawinecka, Daniela Varges & Inga Zerr. (2010) Codon 129 polymorphism and the E200K mutation do not affect the cellular prion protein isoform composition in the cerebrospinal fluid from patients with Creutzfeldt–Jakob disease. European Journal of Neuroscience 31:11, pages 2024-2031.
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Jonathan Scheiman, Jen-Chieh Tseng, Yun Zheng & Daniel Meruelo. (2010) Multiple Functions of the 37/67-kd Laminin Receptor Make It a Suitable Target for Novel Cancer Gene Therapy. Molecular Therapy 18:1, pages 63-74.
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Karl McEvoy & Hilary E.M. McMahon. (2009) Antiprion action of new cyclodextrin analogues. Biochimica et Biophysica Acta (BBA) - General Subjects 1790:10, pages 1382-1386.
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Rafael Linden, Vilma Martins & Marco Prado. (2009) Prion protein. AfCS-Nature Molecule Pages.
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Heike Pflanz, Karen Vana, Gerda Mitteregger, Ingrid Renner-Müller, Claudia Pace, Helmut Küchenhoff, Hans A. Kretzschmar, Eckhard Wolf & Stefan Weiss. (2009) Scrapie-Infected Transgenic Mice Expressing a Laminin Receptor Decoy Mutant Reveal a Prolonged Incubation Time Associated with Low Levels of PrPres. Journal of Molecular Biology 388:4, pages 721-729.
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Vincenza Campana, Lorena Zentilin, Ilaria Mirabile, Agata Kranjc, Philippe Casanova, Mauro Giacca, Stanley B. PrusinerGiuseppe Legname & Chiara Zurzolo. (2009) Development of antibody fragments for immunotherapy of prion diseases. Biochemical Journal 418:3, pages 507-515.
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Robert Hnasko & Cathrin E. Bruederle. (2009) Inoculation of Scrapie with the Self-Assembling RADA-Peptide Disrupts Prion Accumulation and Extends Hamster Survival. PLoS ONE 4:2, pages e4440.
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Alessandro Corsaro, Stefano Thellung, Katia Chiovitti, Valentina Villa, Alessandro Simi, Federica Raggi, Domenico Paludi, Claudio Russo, Antonio Aceto & Tullio Florio. (2009) Dual Modulation of ERK1/2 and p38 MAP Kinase Activities Induced by Minocycline Reverses the Neurotoxic Effects of the Prion Protein Fragment 90–231. Neurotoxicity Research 15:2, pages 138-154.
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H. Pflanz, K. Vana, G. Mitteregger, C. Pace, D. Messow, C. Sedlaczek, D. Nikles, H. A. Kretzschmar & S. F. T. Weiss. (2009) Microinjection of lentiviral vectors expressing small interfering RNAs directed against laminin receptor precursor mRNA prolongs the pre-clinical phase in scrapie-infected mice. Journal of General Virology 90:1, pages 269-274.
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Lara Soler, Patrick Caffrey & Hilary E.M. McMahon. (2008) Effects of new amphotericin analogues on the scrapie isoform of the prion protein. Biochimica et Biophysica Acta (BBA) - General Subjects 1780:10, pages 1162-1167.
Crossref
Chantal Zuber, Gerda Mitteregger, Natascha Schuhmann, Clémence Rey, Stefan Knackmuss, Wolfgang Rupprecht, Uwe Reusch, Claudia Pace, Melvyn Little, Hans A. Kretzschmar, Michael Hallek, Hildegard Büning & Stefan Weiss. (2008) Delivery of single-chain antibodies (scFvs) directed against the 37/67 kDa laminin receptor into mice via recombinant adeno-associated viral vectors for prion disease gene therapy. Journal of General Virology 89:8, pages 2055-2061.
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Chantal Zuber, Stefan Knackmuss, Georgeta Zemora, Uwe Reusch, Ekaterina Vlasova, Daniela Diehl, Vera Mick, Karin Hoffmann, Daphne Nikles, Thomas Fröhlich, Georg J. Arnold, Bertram Brenig, Eckhard Wolf, Harald Lahm, Melvyn Little & Stefan Weiss. (2008) Invasion of Tumorigenic HT1080 Cells Is Impeded by Blocking or Downregulating the 37-kDa/67-kDa Laminin Receptor. Journal of Molecular Biology 378:3, pages 530-539.
Crossref
Daphne Nikles, Karen Vana, Sabine Gauczynski, Heike Knetsch, Heike Ludewigs & Stefan Weiss. (2008) Subcellular localization of prion proteins and the 37 kDa/67 kDa laminin receptor fused to fluorescent proteins. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1782:5, pages 335-340.
Crossref
SangYun Kim, Hae-Kwan Cheong & Seong Soo An. (2008) Human Prion Diseases. Journal of the Korean Medical Association 51:12, pages 1125.
Crossref
Tharinee Susantad & Duncan Smith. (2008) siRNA-mediated silencing of the 37/67-kDa high affinity laminin receptor in Hep3B cells induces apoptosis. Cellular and Molecular Biology Letters 13:3.
Crossref

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