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Editorial

Why are we afraid of Acinetobacter baumannii?

, &
Pages 269-271 | Published online: 10 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Ish Kumar, Amin Sagar, Kanika Dhiman, Christopher R. Bethel, Andrea M. Hujer, Justin Carifi, Ashish & Robert A. Bonomo. (2023) Insights into dynamic changes in ADC-7 and P99 cephalosporinases using small angle x-ray scattering (SAXS). Journal of Biomolecular Structure and Dynamics 0:0, pages 1-13.
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Prashant Chandra, Rajesh V, Surulivelrajan M, Shastry CS & Unnikrishnan MK. (2022) Multidrug-resistant Acinetobacter baumannii infections: looming threat in the Indian clinical setting. Expert Review of Anti-infective Therapy 20:5, pages 721-732.
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Iain Abbott, Gustavo M Cerqueira, Saruar Bhuiyan & Anton Y Peleg. (2013) Carbapenem resistance in Acinetobacter baumannii: laboratory challenges, mechanistic insights and therapeutic strategies. Expert Review of Anti-infective Therapy 11:4, pages 395-409.
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Articles from other publishers (38)

Sana Azaiez, Marisa Haenni, Asma Ben Cheikh, Mohamed Sahbi Chalbi, Aziza Messaoudi, Lamia Tilouch, Sana Bahri, Antoine Drapeau, Estelle Saras, Mariem Mtibâa, Rania Zouaoui, Houyem Said, Jean-Yves Madec, Agnese Lupo & Wejdene Mansour. (2023) Healthcare Equipment and Personnel Reservoirs of Carbapenem-Resistant Acinetobacter baumannii Epidemic Clones in Intensive Care Units in a Tunisian Hospital. Microorganisms 11:11, pages 2637.
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Jyotirmayee Dey, Soumya Ranjan Mahapatra, Pawan K Singh, Samudyata C. Prabhuswamimath, Namrata Misra & Mrutyunjay Suar. (2023) Designing of multi-epitope peptide vaccine against Acinetobacter baumannii through combined immunoinformatics and protein interaction–based approaches. Immunologic Research 71:4, pages 639-662.
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David Nicholson, Thomas A. Edwards, Alex J. O'Neill & Neil A. Ranson. (2020) Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics. Structure 28:10, pages 1087-1100.e3.
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Yaw Adjei Anane, Teke Apalata, Sandeep Vasaikar, Grace Emily Okuthe & Sandile Phinda Songca. (2020) In vitro antimicrobial photodynamic inactivation of multidrug-resistant Acinetobacter baumannii biofilm using Protoporphyrin IX and Methylene blue. Photodiagnosis and Photodynamic Therapy 30, pages 101752.
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A. Nutman & D. Marchaim. (2019) How to: molecular investigation of a hospital outbreak. Clinical Microbiology and Infection 25:6, pages 688-695.
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Shun Xin Wang-Lin, Ruth Olson, Janet M. Beanan, Ulrike MacDonald, Thomas A. Russo & Joseph P. Balthasar. (2019) Antibody Dependent Enhancement of Acinetobacter baumannii Infection in a Mouse Pneumonia Model . Journal of Pharmacology and Experimental Therapeutics 368:3, pages 475-489.
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Alexandra A. Bouza, Hollister C. Swanson, Kali A. Smolen, Alison L. VanDine, Magdalena A. Taracila, Chiara Romagnoli, Emilia Caselli, Fabio Prati, Robert A. Bonomo, Rachel A. Powers & Bradley J. Wallar. (2017) Structure-Based Analysis of Boronic Acids as Inhibitors of Acinetobacter -Derived Cephalosporinase-7, a Unique Class C β-Lactamase . ACS Infectious Diseases 4:3, pages 325-336.
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Amaro F. Sanchez-Larrayoz, Noha M. Elhosseiny, Marc G. Chevrette, Yang Fu, Peter Giunta, Raúl G. Spallanzani, Keerthikka Ravi, Gerald B. Pier, Stephen Lory & Tomás Maira-Litrán. (2017) Complexity of Complement Resistance Factors Expressed by Acinetobacter baumannii Needed for Survival in Human Serum . The Journal of Immunology 199:8, pages 2803-2814.
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Soraya Rumbo-Feal, Astrid Pérez, Theresa A. Ramelot, Laura Álvarez-Fraga, Juan A. Vallejo, Alejandro Beceiro, Emily J. Ohneck, Brock A. Arivett, María Merino, Steven E. Fiester, Michael A. Kennedy, Luis A. Actis, Germán Bou & Margarita Poza. (2017) Contribution of the A. baumannii A1S_0114 Gene to the Interaction with Eukaryotic Cells and Virulence. Frontiers in Cellular and Infection Microbiology 7.
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Josephine P. Werner, Joshua M. Mitchell, Magdalena A. Taracila, Robert A. Bonomo & Rachel A. Powers. (2017) Exploring the potential of boronic acids as inhibitors of OXA-24/40 β-lactamase. Protein Science 26:3, pages 515-526.
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Scott R. Evans, Andrea M. Hujer, Hongyu Jiang, Carol B. Hill, Kristine M. Hujer, Jose R. Mediavilla, Claudia Manca, Thuy Tien T. Tran, T. Nicholas Domitrovic, Paul G. Higgins, Harald Seifert, Barry N. Kreiswirth, Robin Patel, Michael R. Jacobs, Liang Chen, Rangarajan Sampath, Thomas Hall, Christine Marzan, Vance G. FowlerJr.Jr., Henry F. Chambers & Robert A. Bonomo. (2017) Informing Antibiotic Treatment Decisions: Evaluating Rapid Molecular Diagnostics To Identify Susceptibility and Resistance to Carbapenems against Acinetobacter spp. in PRIMERS III. Journal of Clinical Microbiology 55:1, pages 134-144.
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R. Parra Millán, M. E. Jiménez Mejías, V. Sánchez Encinales, R. Ayerbe Algaba, A. Gutiérrez Valencia, M. E. Pachón Ibáñez, C. Díaz, J. Pérez del Palacio, L. F. López Cortés, J. Pachón & Y. Smani. (2016) Efficacy of Lysophosphatidylcholine in Combination with Antimicrobial Agents against Acinetobacter baumannii in Experimental Murine Peritoneal Sepsis and Pneumonia Models. Antimicrobial Agents and Chemotherapy 60:8, pages 4464-4470.
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Lihua Qi, Hao Li, Chuanfu Zhang, Beibei Liang, Jie Li, Ligui Wang, Xinying Du, Xuelin Liu, Shaofu Qiu & Hongbin Song. (2016) Relationship between Antibiotic Resistance, Biofilm Formation, and Biofilm-Specific Resistance in Acinetobacter baumannii. Frontiers in Microbiology 7.
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Rachel A. Powers, Hollister C. Swanson, Magdalena A. Taracila, Nicholas W. Florek, Chiara Romagnoli, Emilia Caselli, Fabio Prati, Robert A. Bonomo & Bradley J. Wallar. (2014) Biochemical and Structural Analysis of Inhibitors Targeting the ADC-7 Cephalosporinase of Acinetobacter baumannii . Biochemistry 53:48, pages 7670-7679.
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Alexander Golberg, G. Felix Broelsch, Daniela Vecchio, Saiqa Khan, Michael R. Hamblin, William G. AustenJr.Jr., Robert L. Sheridan & Martin L. Yarmush. (2014) Eradication of multidrug-resistant A. baumannii in burn wounds by antiseptic pulsed electric field . TECHNOLOGY 02:02, pages 153-160.
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Patrick McGann, Patrice Courvalin, Erik Snesrud, Robert J. Clifford, Eun-Jeong Yoon, Fatma Onmus-Leone, Ana C. Ong, Yoon I. Kwak, Catherine Grillot-Courvalin, Emil Lesho & Paige E. Waterman. (2014) Amplification of Aminoglycoside Resistance Gene aphA1 in Acinetobacter baumannii Results in Tobramycin Therapy Failure . mBio 5:2.
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Gopi Patel, Meenakshi M. Rana & Shirish Huprikar. (2013) Multidrug-Resistant Bacteria in Organ Transplantation: An Emerging Threat with Limited Therapeutic Options. Current Infectious Disease Reports 15:6, pages 504-513.
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Daniel L. Zimbler, Brock A. Arivett, Amber C. Beckett, Sharon M. Menke & Luis A. Actis. (2013) Functional Features of TonB Energy Transduction Systems of Acinetobacter baumannii. Infection and Immunity 81:9, pages 3382-3394.
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Dinh-Duc Nguyen, Ho-Phuong-Thuy Ngo, Myoung-ki Hong, Tan-Viet Pham, Jung Hun Lee, Jae Jin Lee, Dae Beom Kwon, Sang Hee Lee & Lin-Woo Kang. (2013) Expression, crystallization and preliminary X-ray crystallographic analysis of alanine racemase from Acinetobacter baumannii OXA-23 . Acta Crystallographica Section F Structural Biology and Crystallization Communications 69:9, pages 1041-1044.
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S.H. FengA. StojadinovicM. Izadjoo. (2013) Distinctive stages and strain variations of A. baumannii biofilm development under shear flow . Journal of Wound Care 22:4, pages 173-181.
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Thomas A. Russo, Janet M. Beanan, Ruth Olson, Ulrike MacDonald, Andrew D. Cox, Frank St. Michael, Evgeny V. Vinogradov, Brad Spellberg, Nicole R. Luke-Marshall & Anthony A. Campagnari. (2013) The K1 Capsular Polysaccharide from Acinetobacter baumannii Is a Potential Therapeutic Target via Passive Immunization. Infection and Immunity 81:3, pages 915-922.
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Salome N. Seiffert, Markus Hilty, Vincent Perreten & Andrea Endimiani. (2013) Extended-spectrum cephalosporin-resistant gram-negative organisms in livestock: An emerging problem for human health?. Drug Resistance Updates 16:1-2, pages 22-45.
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B.S. Lopes, L. Al-Hassan & S.G.B. Amyes. (2012) ISAba825 controls the expression of the chromosomal b/aOXA-51-like and the plasmid borne blaOXA-58 gene in clinical isolates of Acinetobacter baumannii isolated from the USA. Clinical Microbiology and Infection 18:11, pages E446-E451.
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Amanda L. Garner, Sook Kyung Kim, Jie Zhu, Anjali Kumari Struss, Richard Watkins, Brent D. Feske, Gunnar F. Kaufmann & Kim D. Janda. (2012) Stereochemical Insignificance Discovered in Acinetobacter baumannii Quorum Sensing. PLoS ONE 7:5, pages e37102.
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Francesco Imperi, Luísa C.S. Antunes, Jochen Blom, Laura Villa, Michele Iacono, Paolo Visca & Alessandra Carattoli. (2011) The genomics of Acinetobacter baumannii : Insights into genome plasticity, antimicrobial resistance and pathogenicity . IUBMB Life 63:12, pages 1068-1074.
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Qiang Tan, Aimie M. Ogawa, Susan L. Raghoobar, Douglas Wisniewski, Lawrence Colwell, Young-Whan Park, Katherine Young, Jeffrey D. Hermes, Frank P. DiNinno & Milton L. Hammond. (2011) Thiophenyl oxime-derived phosphonates as nano-molar class C beta-lactamase inhibitors reducing MIC of imipenem against Pseudomonas aeruginosa and Acinetobacter baumannii. Bioorganic & Medicinal Chemistry Letters 21:14, pages 4363-4365.
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Younes Smani, Fernando Docobo-Pérez, Michael J. McConnell & Jerónimo Pachón. (2011) Acinetobacter baumannii-induced lung cell death: Role of inflammation, oxidative stress and cytosolic calcium. Microbial Pathogenesis 50:5, pages 224-232.
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T. A. Russo, M. G. P. Page, J. M. Beanan, R. Olson, A. M. Hujer, K. M. Hujer, M. Jacobs, S. Bajaksouzian, A. Endimiani & R. A. Bonomo. (2011) In vivo and in vitro activity of the siderophore monosulfactam BAL30072 against Acinetobacter baumannii. Journal of Antimicrobial Chemotherapy 66:4, pages 867-873.
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Pablo Ravasi, Adriana S. Limansky, Ramiro E. Rodriguez, Alejandro M. Viale & María A. Mussi. (2011) ISAba825, a Functional Insertion Sequence Modulating Genomic Plasticity and bla OXA-58 Expression in Acinetobacter baumannii . Antimicrobial Agents and Chemotherapy 55:2, pages 917-920.
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Xavier Ragàs, Tianhong Dai, George P. Tegos, Montserrat Agut, Santi Nonell & Michael R. Hamblin. (2010) Photodynamic inactivation of Acinetobacter baumannii using phenothiazinium dyes: In vitro and in vivo studies. Lasers in Surgery and Medicine 42:5, pages 384-390.
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Nicole R. Luke, Shauna L. Sauberan, Thomas A. Russo, Janet M. Beanan, Ruth Olson, Thomas W. Loehfelm, Andrew D. Cox, Frank St. Michael, Evgeny V. Vinogradov & Anthony A. Campagnari. (2010) Identification and Characterization of a Glycosyltransferase Involved in Acinetobacter baumannii Lipopolysaccharide Core Biosynthesis . Infection and Immunity 78:5, pages 2017-2023.
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Qiang Tan, Aimie M. Ogawa, Ronald E. Painter, Young-Whan Park, Katherine Young & Frank P. DiNinno. (2010) 4,7-Dichloro benzothien-2-yl sulfonylaminomethyl boronic acid: First boronic acid-derived beta-lactamase inhibitor with class A, C, and D activity. Bioorganic & Medicinal Chemistry Letters 20:8, pages 2622-2624.
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Dubert M. GuerreroFederico PerezNicholas G. CongerJoseph S. SolomkinMark D. AdamsPhilip N. RatherRobert A. Bonomo. (2010) Acinetobacter baumannii -Associated Skin and Soft Tissue Infections: Recognizing a Broadening Spectrum of Disease . Surgical Infections 11:1, pages 49-57.
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Sarah M. Drawz, Maja Babic, Christopher R. Bethel, Magda Taracila, Anne M. Distler, Claudia Ori, Emilia Caselli, Fabio Prati & Robert A. Bonomo. (2009) Inhibition of the Class C β-Lactamase from Acinetobacter spp.: Insights into Effective Inhibitor Design . Biochemistry 49:2, pages 329-340.
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Tianhong Dai, George P. Tegos, Zongshun Lu, Liyi Huang, Timur Zhiyentayev, Michael J. Franklin, David G. Baer & Michael R. Hamblin. (2009) Photodynamic Therapy for Acinetobacter baumannii Burn Infections in Mice . Antimicrobial Agents and Chemotherapy 53:9, pages 3929-3934.
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Daniel L. Zimbler, William F. Penwell, Jennifer A. Gaddy, Sharon M. Menke, Andrew P. Tomaras, Pamela L. Connerly & Luis A. Actis. (2009) Iron acquisition functions expressed by the human pathogen Acinetobacter baumannii. BioMetals 22:1, pages 23-32.
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