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Glycoengineered cell models for the characterization of cancer O-glycoproteome: an innovative strategy for biomarker discovery

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Daniela Freitas, Meritxell Balmaña, Juliana Poças, Diana Campos, Hugo Osório, Andriana Konstantinidi, Sergey Y. Vakhrushev, Ana Magalhães & Celso A. Reis. (2019) Different isolation approaches lead to diverse glycosylated extracellular vesicle populations. Journal of Extracellular Vesicles 8:1.
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Francisca Diniz, Sofia Lamas, Hugo Osório, Paulo Aguiar, Daniela Freitas, Fátima Gartner, Bruno Sarmento, Celso A. Reis & Joana Gomes. (2023) Nanoparticles targeting Sialyl-Tn for efficient tyrosine kinase inhibitor delivery in gastric cancer. Acta Biomaterialia.
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Francisca Diniz, Maria Azevedo, Flávia Sousa, Hugo Osório, Diana Campos, Paula Sampaio, Joana Gomes, Bruno Sarmento & Celso A. Reis. (2022) Polymeric nanoparticles targeting Sialyl-Tn in gastric cancer: A live tracking under flow conditions. Materials Today Bio 16, pages 100417.
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Kwong Y. Tsang, Massimo Fantini, Anjum Zaki, Sharon A. Mavroukakis, Maria Pia Morelli, Christina M. Annunziata & Philip M. Arlen. (2022) Identification of the O-Glycan Epitope Targeted by the Anti-Human Carcinoma Monoclonal Antibody (mAb) NEO-201. Cancers 14:20, pages 4999.
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Álvaro M. Martins, Cátia C. Ramos, Daniela Freitas & Celso A. Reis. (2021) Glycosylation of Cancer Extracellular Vesicles: Capture Strategies, Functional Roles and Potential Clinical Applications. Cells 10:1, pages 109.
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Daniela Freitas, Diana Campos, Joana Gomes, Filipe Pinto, Joana A. Macedo, Rita Matos, Stefan Mereiter, Marta T. Pinto, António Polónia, Fátima Gartner, Ana Magalhães & Celso A. Reis. (2019) O-glycans truncation modulates gastric cancer cell signaling and transcription leading to a more aggressive phenotype. EBioMedicine 40, pages 349-362.
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José Alexandre Ferreira, Ana Magalhães, Joana Gomes, Andreia Peixoto, Cristiana Gaiteiro, Elisabete Fernandes, Lúcio Lara Santos & Celso A. Reis. (2017) Protein glycosylation in gastric and colorectal cancers: Toward cancer detection and targeted therapeutics. Cancer Letters 387, pages 32-45.
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Henrique Duarte, Daniela Freitas, Catarina Gomes, Joana Gomes, Ana Magalhães & Celso Reis. (2016) Mucin-Type O-Glycosylation in Gastric Carcinogenesis. Biomolecules 6:3, pages 33.
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Cheng-Siang Lee, Nur Aishah Mohd Taib, Ali Ashrafzadeh, Farhana Fadzli, Faizah Harun, Kartini Rahmat, See Mee Hoong, Puteri Shafinaz Abdul-Rahman & Onn Haji Hashim. (2016) Unmasking Heavily O-Glycosylated Serum Proteins Using Perchloric Acid: Identification of Serum Proteoglycan 4 and Protease C1 Inhibitor as Molecular Indicators for Screening of Breast Cancer. PLOS ONE 11:2, pages e0149551.
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José Alexandre Ferreira, Andreia Peixoto, Manuel Neves, Cristiana Gaiteiro, Celso A. Reis, Yehuda G. Assaraf & Lúcio Lara Santos. (2016) Mechanisms of cisplatin resistance and targeting of cancer stem cells: Adding glycosylation to the equation. Drug Resistance Updates 24, pages 34-54.
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