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Editorial

Proteomic methods for biomarker discovery and validation. Are we there yet?

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Konstantinos Makris, Alexander Haliassos, Maria Chondrogianni & Georgios Tsivgoulis. (2018) Blood biomarkers in ischemic stroke: potential role and challenges in clinical practice and research. Critical Reviews in Clinical Laboratory Sciences 55:5, pages 294-328.
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Sandra Murphy, Margit Zweyer, Rustam R. Mundegar, Dieter Swandulla & Kay Ohlendieck. (2018) Proteomic serum biomarkers for neuromuscular diseases. Expert Review of Proteomics 15:3, pages 277-291.
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Abdo Alnabulsi & Graeme I Murray. (2016) Integrative analysis of the colorectal cancer proteome: potential clinical impact. Expert Review of Proteomics 13:10, pages 917-927.
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Iakes Ezkurdia, Enrique Calvo, Angela Del Pozo, Jesús Vázquez, Alfonso Valencia & Michael L. Tress. (2015) The potential clinical impact of the release of two drafts of the human proteome. Expert Review of Proteomics 12:6, pages 579-593.
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Articles from other publishers (20)

Sonja Schiffer, Stephan Schwers & Stefan Heitmeier. (2023) The effect of rivaroxaban on biomarkers in blood and plasma: a review of preclinical and clinical evidence. Journal of Thrombosis and Thrombolysis 55:3, pages 449-463.
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Susannah Hallal, Ali Azimi, Heng Wei, Nicholas Ho, Maggie Yuk Ting Lee, Hao-Wen Sim, Joanne Sy, Brindha Shivalingam, Michael Edward Buckland & Kimberley Louise Alexander-Kaufman. (2020) A Comprehensive Proteomic SWATH-MS Workflow for Profiling Blood Extracellular Vesicles: A New Avenue for Glioma Tumour Surveillance. International Journal of Molecular Sciences 21:13, pages 4754.
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Farah J. Nassar, Ghada Chamandi, Mohamad Ali Tfaily, Nathalie Khoueiry Zgheib & Rihab Nasr. (2020) Peripheral Blood-Based Biopsy for Breast Cancer Risk Prediction and Early Detection. Frontiers in Medicine 7.
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Nicholas J. ShubinKrupa NavalkarDayle SampsonThomas D. YagerSilvia CermelliTherese SeldonErin SullivanJerry J. ZimmermanLester C. PermutAdrian M. Piliponsky. (2020) Serum Protein Changes in Pediatric Sepsis Patients Identified With an Aptamer-Based Multiplexed Proteomic Approach. Critical Care Medicine 48:1, pages e48-e57.
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Paola Sebastiani, Stefano Monti, Melody Morris, Anastasia Gurinovich, Tanaka Toshiko, Stacy L. Andersen, Benjamin Sweigart, Luigi Ferrucci, Lori L. Jennings, David J. Glass & Thomas T. Perls. (2019) A serum protein signature of APOE genotypes in centenarians . Aging Cell 18:6.
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Robert F. Hillary, Daniel L. McCartney, Sarah E. Harris, Anna J. Stevenson, Anne Seeboth, Qian Zhang, David C. Liewald, Kathryn L. Evans, Craig W. Ritchie, Elliot M. Tucker-Drob, Naomi R. Wray, Allan F. McRae, Peter M. Visscher, Ian J. Deary & Riccardo E. Marioni. (2019) Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936. Nature Communications 10:1.
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Tomasz Burzykowski, Jürgen Claesen & Dirk Valkenborg. 2019. Mass Spectrometry of Proteins. Mass Spectrometry of Proteins 181 197 .
Priscila M. Kosaka, Montserrat Calleja & Javier Tamayo. (2018) Optomechanical devices for deep plasma cancer proteomics. Seminars in Cancer Biology 52, pages 26-38.
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W. Michael DunneJrJr, Hannes Pouseele, Stefan Monecke, Ralf Ehricht & Alex van Belkum. (2018) Epidemiology of transmissible diseases: Array hybridization and next generation sequencing as universal nucleic acid-mediated typing tools. Infection, Genetics and Evolution 63, pages 332-345.
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Aoife M. Curran, Marie Pier Scott-Boyer, Jim Kaput, Miriam F. Ryan, Elaine Drummond, Eileen R. Gibney, Michael J. Gibney, Helen M. Roche & Lorraine Brennan. (2018) A proteomic signature that reflects pancreatic beta-cell function. PLOS ONE 13:8, pages e0202727.
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Zhizhou Kuang, Ruochun Huang, Zhimin Yang, Zhiqiang Lv, Xinyan Chen, Fuping Xu, Yu-Hua Yi, Jian Wu & Ruo-Pan Huang. (2018) Quantitative screening of serum protein biomarkers by reverse phase protein arrays. Oncotarget 9:66, pages 32624-32641.
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Peter J. Wermuth, Sonsoles Piera-Velazquez, Joel Rosenbloom & Sergio A. Jimenez. (2018) Existing and novel biomarkers for precision medicine in systemic sclerosis. Nature Reviews Rheumatology 14:7, pages 421-432.
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Muhammad Zubair Israr, Liam M. Heaney & Toru Suzuki. (2018) Proteomic Biomarkers of Heart Failure. Heart Failure Clinics 14:1, pages 93-107.
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Héctor Quezada, Ana Laura Guzmán-Ortiz, Hugo Díaz-Sánchez, Ricardo Valle-Rios & Jesús Aguirre-Hernández. (2017) Omics-based biomarkers: current status and potential use in the clinic. Boletín Médico del Hospital Infantil de México 74:3, pages 219-226.
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Héctor Quezada, Ana Laura Guzmán-Ortiz, Hugo Díaz-Sánchez, Ricardo Valle-Rios & Jesús Aguirre-Hernández. (2017) Omics-based biomarkers: current status and potential use in the clinic. Boletín Médico Del Hospital Infantil de México (English Edition) 74:3, pages 219-226.
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Zhaohui Chen & Jayoung Kim. (2016) Urinary proteomics and metabolomics studies to monitor bladder health and urological diseases. BMC Urology 16:1.
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Yetrib Hathout, Haeri Seol, Meng Hsuan J. Han, Aiping Zhang, Kristy J. Brown & Eric P. Hoffman. (2016) Clinical utility of serum biomarkers in Duchenne muscular dystrophy. Clinical Proteomics 13:1.
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Mika Ala-Korpela & George Davey Smith. (2016) Metabolic profiling–multitude of technologies with great research potential, but (when) will translation emerge?. International Journal of Epidemiology 45:5, pages 1311-1318.
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Yetrib Hathout, Laurie S. Conklin, Haeri Seol, Heather Gordish-Dressman, Kristy J. Brown, Lauren P. Morgenroth, Kanneboyina Nagaraju, Christopher R. Heier, Jesse M. Damsker, John N. van den Anker, Erik Henricson, Paula R. Clemens, Jean K. Mah, Craig McDonald & Eric P. Hoffman. (2016) Serum pharmacodynamic biomarkers for chronic corticosteroid treatment of children. Scientific Reports 6:1.
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Boris Y. Zaslavsky, Vladimir N. Uversky & Arnon Chait. (2016) Analytical applications of partitioning in aqueous two-phase systems: Exploring protein structural changes and protein–partner interactions in vitro and in vivo by solvent interaction analysis method. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1864:5, pages 622-644.
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