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Review

Biochemistry of Tau in Alzheimer’s disease and related neurological disorders

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Pages 207-224 | Published online: 09 Jan 2014

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Crossref
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Crossref
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Crossref
Claudia A. Razzino, Verónica Serafín, Maria Gamella, María Pedrero, Ana Montero-Calle, Rodrigo Barderas, Miguel Calero, Anderson O. Lobo, Paloma Yáñez-Sedeño, Susana Campuzano & José M. Pingarrón. (2020) An electrochemical immunosensor using gold nanoparticles-PAMAM-nanostructured screen-printed carbon electrodes for tau protein determination in plasma and brain tissues from Alzheimer patients. Biosensors and Bioelectronics 163, pages 112238.
Crossref
Pankaj Wadhwa, Priti Jain & Hemant R. Jadhav. (2020) Glycogen Synthase Kinase 3 (GSK3): Its Role and Inhibitors. Current Topics in Medicinal Chemistry 20:17, pages 1522-1534.
Crossref
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Crossref
Hariharakrishnan Chidambaram & Subashchandrabose Chinnathambi. (2020) G-Protein Coupled Receptors and Tau-different Roles in Alzheimer’s Disease. Neuroscience 438, pages 198-214.
Crossref
Owen Sanders & Lekshmy Rajagopal. (2020) Phosphodiesterase Inhibitors for Alzheimer’s Disease: A Systematic Review of Clinical Trials and Epidemiology with a Mechanistic Rationale. Journal of Alzheimer's Disease Reports 4:1, pages 185-215.
Crossref
Satya P. Gupta & Vaishali M. Patil. (2020) Recent Studies on Design and Development of Drugs Against Alzheimer’s Disease (AD) Based on Inhibition of BACE-1 and Other AD-causative Agents. Current Topics in Medicinal Chemistry 20:13, pages 1195-1213.
Crossref
Ahmad Abu Turab Naqvi, Gulam Mustafa Hasan & Md. Imtaiyaz Hassan. (2020) Targeting Tau Hyperphosphorylation via Kinase Inhibition: Strategy to Address Alzheimer's Disease. Current Topics in Medicinal Chemistry 20:12, pages 1059-1073.
Crossref
Adrianna Wysocka, Ewelina Palasz, Marta Steczkowska & Grazyna Niewiadomska. (2020) Dangerous Liaisons: Tau Interaction with Muscarinic Receptors. Current Alzheimer Research 17:3, pages 224-237.
Crossref
Botond Penke, Mária Szűcs & Ferenc Bogár. (2020) Oligomerization and Conformational Change Turn Monomeric β-Amyloid and Tau Proteins Toxic: Their Role in Alzheimer’s Pathogenesis. Molecules 25:7, pages 1659.
Crossref
Florence Clavaguera, Charles Duyckaerts & Stéphane Haïk. (2020) Prion-like properties of Tau assemblies. Current Opinion in Neurobiology 61, pages 49-57.
Crossref
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Crossref
Lata Rani, Jeetain Mittal & Sairam S. Mallajosyula. (2020) Effect of Phosphorylation and O-GlcNAcylation on Proline-Rich Domains of Tau. The Journal of Physical Chemistry B 124:10, pages 1909-1918.
Crossref
Marta Fernández-Nogales & José J. Lucas. (2020) Altered Levels and Isoforms of Tau and Nuclear Membrane Invaginations in Huntington’s Disease. Frontiers in Cellular Neuroscience 13.
Crossref
Morvane Colin, Simon Dujardin, Susanna Schraen-Maschke, Guy Meno-Tetang, Charles Duyckaerts, Jean-Philippe Courade & Luc Buée. (2019) From the prion-like propagation hypothesis to therapeutic strategies of anti-tau immunotherapy. Acta Neuropathologica 139:1, pages 3-25.
Crossref
Sabrina Bimonte, Antonio Barbieri, Nagoth Joseph Amruthraj, Marco Cascella, Arturo Cuomo & Claudio Arra. 2020. General Anesthesia Research. General Anesthesia Research 207 223 .
Chiara A. De Benedictis, Antonietta Vilella & Andreas M. Grabrucker. 2019. Alzheimer’s Disease. Alzheimer’s Disease 85 106 .
Kevin Carvalho, Emilie Faivre, Marie J Pietrowski, Xavier Marques, Victoria Gomez-Murcia, Aude Deleau, Vincent Huin, Jan N Hansen, Stanislav Kozlov, Clément Danis, Mariana Temido-Ferreira, Joana E Coelho, Céline Mériaux, Sabiha Eddarkaoui, Stéphanie Le Gras, Mélanie Dumoulin, Lucrezia Cellai, Isabelle Landrieu, Yijuang Chern, Malika Hamdane, Luc Buée, Anne-Laurence Boutillier, Sabine Levi, Annett Halle, Luisa V Lopes & David Blum. (2019) Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor. Brain 142:11, pages 3636-3654.
Crossref
Ester Tellone, Antonio Galtieri, Annamaria Russo & Silvana Ficarra. (2019) Protective Effects of the Caffeine Against Neurodegenerative Diseases. Current Medicinal Chemistry 26:27, pages 5137-5151.
Crossref
Ko, Chiou, Wong, Wang, Lai, Chou, Wang, Loh, Lieu, Cheng, Lin, Lu, Fann, Huang & Hong. (2019) GSKIP-Mediated Anchoring Increases Phosphorylation of Tau by PKA but Not by GSK3beta via cAMP/PKA/GSKIP/GSK3/Tau Axis Signaling in Cerebrospinal Fluid and iPS Cells in Alzheimer Disease. Journal of Clinical Medicine 8:10, pages 1751.
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Stefania Zappettini, Emilie Faivre, Antoine Ghestem, Sébastien Carrier, Luc Buée, David Blum, Monique Esclapez & Christophe Bernard. (2019) Caffeine Consumption During Pregnancy Accelerates the Development of Cognitive Deficits in Offspring in a Model of Tauopathy. Frontiers in Cellular Neuroscience 13.
Crossref
Laetitia Miguel, Anne Rovelet-Lecrux, Maxime Feyeux, Thierry Frebourg, Pierre Nassoy, Dominique Campion & Magalie Lecourtois. (2019) Detection of all adult Tau isoforms in a 3D culture model of iPSC-derived neurons. Stem Cell Research 40, pages 101541.
Crossref
Jordan Hervy & Dominique J. Bicout. (2019) Dynamical decoration of stabilized-microtubules by Tau-proteins. Scientific Reports 9:1.
Crossref
Mario Hofweber & Dorothee Dormann. (2019) Friend or foe—Post-translational modifications as regulators of phase separation and RNP granule dynamics. Journal of Biological Chemistry 294:18, pages 7137-7150.
Crossref
Antoine Leboucher, Tariq Ahmed, Emilie Caron, Anne Tailleux, Sylvie Raison, Aurélie Joly-Amado, Elodie Marciniak, Kevin Carvalho, Malika Hamdane, Kadiombo Bantubungi, Steve Lancel, Sabiha Eddarkaoui, Raphaelle Caillierez, Emmanuelle Vallez, Bart Staels, Didier Vieau, Detlef Balschun, Luc Buee & David Blum. (2019) Brain insulin response and peripheral metabolic changes in a Tau transgenic mouse model. Neurobiology of Disease 125, pages 14-22.
Crossref
Eftychia Vasili, Antonio Dominguez-Meijide & Tiago Fleming Outeiro. (2019) Spreading of α-Synuclein and Tau: A Systematic Comparison of the Mechanisms Involved. Frontiers in Molecular Neuroscience 12.
Crossref
Cheril Tapia-Rojas, Fabian Cabezas-Opazo, Carol A. Deaton, Erick H. Vergara, Gail V.W. Johnson & Rodrigo A. Quintanilla. (2019) It’s all about tau. Progress in Neurobiology 175, pages 54-76.
Crossref
Dongdong Chai, Yanyong Cheng & Hong Jiang. (2018) Fundamentals of fetal toxicity relevant to sevoflurane exposures during pregnancy. International Journal of Developmental Neuroscience 72:1, pages 31-35.
Crossref
Yuzuru Taguchi, Hiroki Otaki & Noriyuki Nishida. (2019) Mechanisms of Strain Diversity of Disease-Associated in-Register Parallel β-Sheet Amyloids and Implications About Prion Strains. Viruses 11:2, pages 110.
Crossref
Md Nazmul Huda & Cheol-Ho Pan. 2019. Cognitive Disorders. Cognitive Disorders.
Franc Llorens, Anna Villar-Piqué, Niccolò Candelise, Isidre Ferrer & Inga Zerr. 2019. Cognitive Disorders. Cognitive Disorders.
Akhlaq A. Farooqui. 2019. Molecular Mechanisms of Dementia. Molecular Mechanisms of Dementia 73 112 .
Maud Gratuze, Aurélie Joly-Amado, Luc Buee, Didier Vieau & David Blum. 2019. Tau Biology. Tau Biology 259 287 .
Nisha, Pragati, Shweta Tandon, Aqsa, Prerna Aggarwal & Surajit Sarkar. 2019. Insights into Human Neurodegeneration: Lessons Learnt from Drosophila. Insights into Human Neurodegeneration: Lessons Learnt from Drosophila 223 250 .
Heng Zhang, Xueyong Zhu, Gabriel Pascual, Jehangir S. Wadia, Elissa Keogh, Jeroen J. Hoozemans, Berdien Siregar, Hanna Inganäs, Esther J.M. Stoop, Jaap Goudsmit, Adrian Apetri, Wouter Koudstaal & Ian A. Wilson. (2018) Structural Basis for Recognition of a Unique Epitope by a Human Anti-tau Antibody. Structure 26:12, pages 1626-1634.e4.
Crossref
Rubayat Islam Khan, Saif Nirzhor & Barnaly Rashid. (2018) A Closer Look into the Role of Protein Tau in the Identification of Promising Therapeutic Targets for Alzheimer’s Disease. Brain Sciences 8:9, pages 162.
Crossref
David Seynnaeve, Mara Vecchio, Gernot Fruhmann, Joke Verelst, Melody Cools, Jimmy Beckers, Daniel Mulvihill, Joris Winderickx & Vanessa Franssens. (2018) Recent Insights on Alzheimer’s Disease Originating from Yeast Models. International Journal of Molecular Sciences 19:7, pages 1947.
Crossref
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Crossref
Yasmina Talmat-Amar, Yoan Arribat & Marie-Laure Parmentier. (2018) Vesicular Axonal Transport is Modified In Vivo by Tau Deletion or Overexpression in Drosophila. International Journal of Molecular Sciences 19:3, pages 744.
Crossref
Cyril Laurent, Luc Buée & David Blum. (2018) Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies?. Biomedical Journal 41:1, pages 21-33.
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Crossref
Isidro Ferrer. 2018. Brain Banking. Brain Banking 285 302 .
Carlos Navarro-Retamal & Julio Caballero. 2018. Computational Modeling of Drugs Against Alzheimer’s Disease. Computational Modeling of Drugs Against Alzheimer’s Disease 305 345 .
Richard Rubenstein, Binggong Chang, Natalia Grinkina, Eleanor Drummond, Peter Davies, Meir Ruditzky, Deep Sharma, Kevin Wang & Thomas Wisniewski. (2017) Tau phosphorylation induced by severe closed head traumatic brain injury is linked to the cellular prion protein. Acta Neuropathologica Communications 5:1.
Crossref
Cyril Laurent, Guillaume Dorothée, Stéphane Hunot, Elodie Martin, Cécile Delarasse, Luc Buée & David Blum. (2017) Tau et troubles cognitifs. médecine/sciences 33:10, pages 817-819.
Crossref
Elodie Marciniak, Antoine Leboucher, Emilie Caron, Tariq Ahmed, Anne Tailleux, Julie Dumont, Tarik Issad, Ellen Gerhardt, Patrick Pagesy, Margaux Vileno, Clément Bournonville, Malika Hamdane, Kadiombo Bantubungi, Steve Lancel, Dominique Demeyer, Sabiha Eddarkaoui, Emmanuelle Vallez, Didier Vieau, Sandrine Humez, Emilie Faivre, Benjamin Grenier-Boley, Tiago F. Outeiro, Bart Staels, Philippe Amouyel, Detlef Balschun, Luc Buee & David Blum. (2017) Tau deletion promotes brain insulin resistance. Journal of Experimental Medicine 214:8, pages 2257-2269.
Crossref
Judith M. van der Harg, Leslie Eggels, Fabian N. Bangel, Silvie R. Ruigrok, Rob Zwart, Jeroen J.M. Hoozemans, Susanne E. la Fleur & Wiep Scheper. (2017) Insulin deficiency results in reversible protein kinase A activation and tau phosphorylation. Neurobiology of Disease 103, pages 163-173.
Crossref
Joana Oliveira, Márcio Costa, Maria Soares Cachide de Almeida, Odete A.B. da Cruz e Silva & Ana Gabriela Henriques. (2017) Protein Phosphorylation is a Key Mechanism in Alzheimer’s Disease. Journal of Alzheimer's Disease 58:4, pages 953-978.
Crossref
Anna Chiarini, Ubaldo Armato, Emanuela Gardenal, Li Gui & Ilaria Dal Prà. (2017) Amyloid β-Exposed Human Astrocytes Overproduce Phospho-Tau and Overrelease It within Exosomes, Effects Suppressed by Calcilytic NPS 2143—Further Implications for Alzheimer's Therapy. Frontiers in Neuroscience 11.
Crossref
Burak Derkus, Pinar Acar Bozkurt, Metin Tulu, Kaan C. Emregul, Canan Yucesan & Emel Emregul. (2017) Simultaneous quantification of Myelin Basic Protein and Tau proteins in cerebrospinal fluid and serum of Multiple Sclerosis patients using nanoimmunosensor. Biosensors and Bioelectronics 89, pages 781-788.
Crossref
Cyril Laurent, Guillaume Dorothée, Stéphane Hunot, Elodie Martin, Yann Monnet, Marie Duchamp, Yuan Dong, François-Pierre Légeron, Antoine Leboucher, Sylvie Burnouf, Emilie Faivre, Kévin Carvalho, Raphaëlle Caillierez, Nadège Zommer, Dominique Demeyer, Nathalie Jouy, Veronique Sazdovitch, Susanna Schraen-Maschke, Cécile Delarasse, Luc Buée & David Blum. (2017) Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy. Brain 140:1, pages 184-200.
Crossref
Gernot Fruhmann, David Seynnaeve, Ju Zheng, Karen Ven, Sofie Molenberghs, Tobias Wilms, Beidong Liu, Joris Winderickx & Vanessa Franssens. (2017) Yeast buddies helping to unravel the complexity of neurodegenerative disorders. Mechanisms of Ageing and Development 161, pages 288-305.
Crossref
Morgan Newman, Doris Kretzschmar, Imran Khan, Mengqi Chen, Giuseppe Verdile & Michael Lardelli. 2017. Animal Models for the Study of Human Disease. Animal Models for the Study of Human Disease 1031 1085 .
Alexandre de Mendonca, David Blum & Jonathan D. Geiger. 2017. Adenosine Receptors in Neurodegenerative Diseases. Adenosine Receptors in Neurodegenerative Diseases 175 186 .
Rotem Maoz, Benjamin P. Garfinkel & Hermona Soreq. 2017. Neuroepigenomics in Aging and Disease. Neuroepigenomics in Aging and Disease 337 361 .
Nicolas Sergeant, Francisco-Jose Fernandez-Gomez, Helene Obriot, Sabiha Eddarkaoui, Valérie Buée-Scherrer & Luc Buée. 2017. Tau Protein. Tau Protein 251 261 .
Anna Lucia Fallacara, Iuni Margaret Laura Trist, Silvia Schenone & Maurizio Botta. 2017. Alzheimer’s Disease II. Alzheimer’s Disease II 119 158 .
Geri Meduri, Kevin Guillemeau, Omar Dounane, Véronique Sazdovitch, Charles Duyckaerts, Béatrice Chambraud, Etienne Emile Baulieu & Julien Giustiniani. (2016) Caspase-cleaved Tau-D421 is colocalized with the immunophilin FKBP52 in the autophagy-endolysosomal system of Alzheimer's disease neurons. Neurobiology of Aging 46, pages 124-137.
Crossref
Kanae Ando, Mikiko Oka, Yosuke Ohtake, Motoki Hayashishita, Sawako Shimizu, Shin-ichi Hisanaga & Koichi M. Iijima. (2016) Tau phosphorylation at Alzheimer's disease-related Ser356 contributes to tau stabilization when PAR-1/MARK activity is elevated. Biochemical and Biophysical Research Communications 478:2, pages 929-934.
Crossref
Elizabeth Gordon, Jonathan D. Rohrer & Nick C. Fox. (2016) Advances in neuroimaging in frontotemporal dementia. Journal of Neurochemistry 138, pages 193-210.
Crossref
Hojjat Alizadeh Zeinabad, Alireza Zarrabian, Ali Akbar Saboury, Ali Mohammad Alizadeh & Mojtaba Falahati. (2016) Interaction of single and multi wall carbon nanotubes with the biological systems: tau protein and PC12 cells as targets. Scientific Reports 6:1.
Crossref
Marius Chiasseu, Jorge L. Cueva Vargas, Laurie Destroismaisons, Christine Vande Velde, Nicole Leclerc & Adriana Di Polo. (2016) Tau Accumulation, Altered Phosphorylation, and Missorting Promote Neurodegeneration in Glaucoma. The Journal of Neuroscience 36:21, pages 5785-5798.
Crossref
Nicolas R. Barthélemy, Audrey Gabelle, Christophe Hirtz, François Fenaille, Nicolas Sergeant, Susanna Schraen-Maschke, Jérôme Vialaret, Luc Buée, Christophe Junot, François Becher & Sylvain Lehmann. (2016) Differential Mass Spectrometry Profiles of Tau Protein in the Cerebrospinal Fluid of Patients with Alzheimer’s Disease, Progressive Supranuclear Palsy, and Dementia with Lewy Bodies. Journal of Alzheimer's Disease 51:4, pages 1033-1043.
Crossref
Nicolas R Barthélemy, François Fenaille, Christophe Hirtz, Nicolas Sergeant, Susanna Schraen-Maschke, Jérôme Vialaret, Luc Buée, Audrey Gabelle, Christophe Junot, Sylvain Lehmann & François Becher. (2016) Tau Protein Quantification in Human Cerebrospinal Fluid by Targeted Mass Spectrometry at High Sequence Coverage Provides Insights into Its Primary Structure Heterogeneity. Journal of Proteome Research 15:2, pages 667-676.
Crossref
Victor L Villemagne & Nobuyuki Okamura. (2016) Tau imaging in the study of ageing, Alzheimer's disease, and other neurodegenerative conditions. Current Opinion in Neurobiology 36, pages 43-51.
Crossref
C Laurent, S Burnouf, B Ferry, V L Batalha, J E Coelho, Y Baqi, E Malik, E Mariciniak, S Parrot, A Van der Jeugd, E Faivre, V Flaten, C Ledent, R D'Hooge, N Sergeant, M Hamdane, S Humez, C E Müller, L V Lopes, L Buée & D Blum. (2014) A2A adenosine receptor deletion is protective in a mouse model of Tauopathy. Molecular Psychiatry 21:1, pages 97-107.
Crossref
Victor L. Villemagne, Nobuyuki Okamura & Christopher C. Rowe. (2016) Untangling tau imaging. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 4:1, pages 39-42.
Crossref
Oliver Wirths, Yvonne Bouter & Thomas A. Bayer. 2016. Neuroscience in the 21st Century. Neuroscience in the 21st Century 3893 3913 .
Mathias Verduyckt, Hélène Vignaud, Tine Bynens, Jeff Van den Brande, Vanessa Franssens, Christophe Cullin & Joris Winderickx. 2016. Systems Biology of Alzheimer's Disease. Systems Biology of Alzheimer's Disease 197 215 .
Marie-Laure Caillet-Boudin, Luc Buée, Nicolas Sergeant & Bruno Lefebvre. (2015) Regulation of human MAPT gene expression. Molecular Neurodegeneration 10:1.
Crossref
J. Sigala, F. Jumeau, L. Buée, N. Sergeant & V. Mitchell. (2015) La protéine microtubulaire Tau testiculaire : une place dans la spermatogenèse ?. Morphologie 99:327, pages 141-148.
Crossref
Pedro Fernandez-Funez, Lorena de Mena & Diego E. Rincon-Limas. (2015) Modeling the complex pathology of Alzheimer's disease in Drosophila. Experimental Neurology 274, pages 58-71.
Crossref
Mingkuan Sun & Liam Chen. (2015) Studying tauopathies in Drosophila: A fruitful model. Experimental Neurology 274, pages 52-57.
Crossref
Marie-Anne Burlot, Jérôme Braudeau, Kristin Michaelsen-Preusse, Brigitte Potier, Sophie Ayciriex, Jennifer Varin, Benoit Gautier, Fathia Djelti, Mickael Audrain, Luce Dauphinot, Francisco-Jose Fernandez-Gomez, Raphaëlle Caillierez, Olivier Laprévote, Ivan Bièche, Nicolas Auzeil, Marie-Claude Potier, Patrick Dutar, Martin Korte, Luc Buée, David Blum & Nathalie Cartier. (2015) Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology. Human Molecular Genetics 24:21, pages 5965-5976.
Crossref
Nicolaas A. Verwey, Yolande A. L. Pijnenburg & Philip Scheltens. 2016. Hodges' Frontotemporal Dementia. Hodges' Frontotemporal Dementia 143 152 .
. 2016. Hodges' Frontotemporal Dementia. Hodges' Frontotemporal Dementia 91 164 .
JUE JIANG & HONG JIANG. (2015) Effect of the inhaled anesthetics isoflurane, sevoflurane and desflurane on the neuropathogenesis of Alzheimer’s disease (Review). Molecular Medicine Reports 12:1, pages 3-12.
Crossref
Maxime Derisbourg, Coline Leghay, Giovanni Chiappetta, Francisco-Jose Fernandez-Gomez, Cyril Laurent, Dominique Demeyer, Sébastien Carrier, Valérie Buée-Scherrer, David Blum, Joëlle Vinh, Nicolas Sergeant, Yann Verdier, Luc Buée & Malika Hamdane. (2015) Role of the Tau N-terminal region in microtubule stabilization revealed by newendogenous truncated forms. Scientific Reports 5:1.
Crossref
Séverine Coutadeur, Hélène Benyamine, Laurence Delalonde, Catherine de Oliveira, Bertrand Leblond, Alicia Foucourt, Thierry Besson, Anne-Sophie Casagrande, Thierry Taverne, Angélique Girard, Matthew P. Pando & Laurent Désiré. (2015) A novel DYRK1A (Dual specificity tyrosine phosphorylation-regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro . Journal of Neurochemistry 133:3, pages 440-451.
Crossref
Sarah N. Fontaine, Jonathan J. Sabbagh, Jeremy Baker, Carlos R. Martinez-Licha, April Darling & Chad A. Dickey. (2015) Cellular factors modulating the mechanism of tau protein aggregation. Cellular and Molecular Life Sciences 72:10, pages 1863-1879.
Crossref
Dae-Young Kim, Sun-Young Jung, Tae-Woon Kim, Kwang-Sik Lee & Kijeong Kim. (2015) Treadmill exercise decreases incidence of Alzheimer’s disease by suppressing glycogen synthase kinase-3β expression in streptozotocin-induced diabetic rats. Journal of Exercise Rehabilitation 11:2, pages 87-94.
Crossref
Katerina Papanikolopoulou & Efthimios M.C. Skoulakis. (2015) Temporally distinct phosphorylations differentiate Tau-dependent learning deficits and premature mortality in Drosophila. Human Molecular Genetics 24:7, pages 2065-2077.
Crossref
Joëlle Rosseels, Jeff Van den Brande, Marie Violet, Dirk Jacobs, Pierre Grognet, Juan Lopez, Isabelle Huvent, Marina Caldara, Erwin Swinnen, Anthony Papegaey, Raphaëlle Caillierez, Valerie Buée-Scherrer, Sebastiaan Engelborghs, Guy Lippens, Morvane Colin, Luc Buée, Marie-Christine Galas, Eugeen Vanmechelen & Joris Winderickx. (2015) Tau Monoclonal Antibody Generation Based on Humanized Yeast Models. Journal of Biological Chemistry 290:7, pages 4059-4074.
Crossref
Tariq Ahmed, David Blum, Sylvie Burnouf, Dominique Demeyer, Valérie Buée-Scherrer, Rudi D'Hooge, Luc Buée & Detlef Balschun. (2015) Rescue of impaired late–phase long-term depression in a tau transgenic mouse model. Neurobiology of Aging 36:2, pages 730-739.
Crossref
Jung-Chi Liao, T. Tony Yang, Rueyhung Roc Weng, Ching-Te Kuo & Chih-Wei Chang. (2015) TTBK2: A Tau Protein Kinase beyond Tau Phosphorylation. BioMed Research International 2015, pages 1-10.
Crossref
David Blum, Federico Herrera, Laetitia Francelle, Tiago Mendes, Marie Basquin, Hélène Obriot, Dominique Demeyer, Nicolas Sergeant, Ellen Gerhardt, Emmanuel Brouillet, Luc Buée & Tiago F. Outeiro. (2015) Mutant huntingtin alters Tau phosphorylation and subcellular distribution. Human Molecular Genetics 24:1, pages 76-85.
Crossref
Victor L Villemagne, Michelle T Fodero-Tavoletti, Colin L Masters & Christopher C Rowe. (2015) Tau imaging: early progress and future directions. The Lancet Neurology 14:1, pages 114-124.
Crossref
Yousuf Ali, Kai Ruan & R. Grace Zhai. 2015. Movement Disorders. Movement Disorders 829 848 .
Oliver Wirths, Yvonne Bouter & Thomas A. Bayer. 2016. Neuroscience in the 21st Century. Neuroscience in the 21st Century 1 21 .
Yu Sun, Jing-hui Liu, Pu Huang, Zong-lou Guo & Li-hong Xu. (2015) Alterations of tau and VASP during microcystin-LR-induced cytoskeletal reorganization in a human liver cell line. Environmental Toxicology 30:1, pages 92-100.
Crossref
Harald Lund, Elin Gustafsson, Anne Svensson, Maria Nilsson, Margareta Berg, Dan Sunnemark & Gabriel von Euler. (2014) MARK4 and MARK3 associate with early tau phosphorylation in Alzheimer’s disease granulovacuolar degeneration bodies. Acta Neuropathologica Communications 2:1.
Crossref
Tariq Ahmed, Ann Van der Jeugd, David Blum, Marie-Christine Galas, Rudi D’Hooge, Luc Buee & Detlef Balschun. (2014) Cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion. Neurobiology of Aging 35:11, pages 2474-2478.
Crossref
Amina Chaalal, Roseline Poirier, David Blum, Brigitte Gillet, Pascale Le Blanc, Marie Basquin, Luc Buée, Serge Laroche & Valérie Enderlin. (2014) PTU-induced hypothyroidism in rats leads to several early neuropathological signs of Alzheimer's disease in the hippocampus and spatial memory impairments. Hippocampus 24:11, pages 1381-1393.
Crossref
Julia E. Gerson, Diana L. Castillo-Carranza & Rakez Kayed. (2014) Advances in Therapeutics for Neurodegenerative Tauopathies: Moving toward the Specific Targeting of the Most Toxic Tau Species. ACS Chemical Neuroscience 5:9, pages 752-769.
Crossref
Cyril Laurent, Sabiha Eddarkaoui, Maxime Derisbourg, Antoine Leboucher, Dominique Demeyer, Sébastien Carrier, Marion Schneider, Malika Hamdane, Christa E. Müller, Luc Buée & David Blum. (2014) Beneficial effects of caffeine in a transgenic model of Alzheimer's disease-like tau pathology. Neurobiology of Aging 35:9, pages 2079-2090.
Crossref
Victor L. Villemagne & Nobuyuki Okamura. (2014) In vivo tau imaging: Obstacles and progress. Alzheimer's & Dementia 10:3S.
Crossref
Hiroki Inoue, Yuuki Hiradate, Yoshiki Shirakata, Kenta Kanai, Keita Kosaka, Aina Gotoh, Yasuhiro Fukuda, Yutaka Nakai, Takafumi Uchida, Eimei Sato & Kentaro Tanemura. (2014) Site‐specific phosphorylation of Tau protein is associated with deacetylation of microtubules in mouse spermatogenic cells during meiosis. FEBS Letters 588:11, pages 2003-2008.
Crossref
María Llorens-Marítin, Jerónimo Jurado, Félix Hernández & Jesús Ãvila. (2014) GSK-3β, a pivotal kinase in Alzheimer disease. Frontiers in Molecular Neuroscience 7.
Crossref
Vanessa Flaten, Cyril Laurent, Joana E. Coelho, Ursula SandauVânia L. Batalha, Sylvie Burnouf, Malika Hamdane, Sandrine Humez, Detlev BoisonLuísa V. Lopes, Luc Buée & David Blum. (2014) From epidemiology to pathophysiology: what about caffeine in Alzheimer's disease?. Biochemical Society Transactions 42:2, pages 587-592.
Crossref
C. Carpentier, D. Ghanem, F.J. Fernandez-Gomez, F. Jumeau, J.V. Philippe, F. Freyermuth, A. Labudeck, S. Eddarkaoui, C.M. Dhaenens, I. Holt, I. Behm-Ansmant, N. Marmier-Gourrier, C. Branlant, N. Charlet-Berguerand, J. Marie, S. Schraen-Maschke, L. Buée, N. Sergeant & M.L. Caillet-Boudin. (2014) Tau exon 2 responsive elements deregulated in myotonic dystrophy type I are proximal to exon 2 and synergistically regulated by MBNL1 and MBNL2. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1842:4, pages 654-664.
Crossref
Julien GiustinianiBéatrice ChambraudElodie SardinOmar DounaneKevin GuillemeauHiroko NakataniDominik Paquet, Amina Kamah, Isabelle Landrieu, Guy Lippens, Etienne-Emile BaulieuMarcel Tawk. (2014) Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy. Proceedings of the National Academy of Sciences 111:12, pages 4584-4589.
Crossref
Anna Mietelska-Porowska, Urszula Wasik, Marcelina Goras, Anna Filipek & Grazyna Niewiadomska. (2014) Tau Protein Modifications and Interactions: Their Role in Function and Dysfunction. International Journal of Molecular Sciences 15:3, pages 4671-4713.
Crossref
Michelle T Fodero-Tavoletti, Shozo Furumoto, Leanne Taylor, Catriona A McLean, Rachel S Mulligan, Ian Birchall, Ryuichi Harada, Colin L Masters, Kazuhiko Yanai, Yukitsuka Kudo, Christopher C Rowe, Nobuyuki Okamura & Victor L Villemagne. (2014) Assessing THK523 selectivity for tau deposits in Alzheimer’s disease and non–Alzheimer’s disease tauopathies. Alzheimer's Research & Therapy 6:1, pages 11.
Crossref
Peng Liu, Li-Bo Zou, Li-Hua Wang, Qing Jiao, Tian-Yan Chi, Xue-Fei Ji & Ge Jin. (2013) Xanthoceraside attenuates tau hyperphosphorylation and cognitive deficits in intracerebroventricular-streptozotocin injected rats. Psychopharmacology 231:2, pages 345-356.
Crossref
Douglas G. Peters & James R. Connor. 2014. Glycobiology of the Nervous System. Glycobiology of the Nervous System 33 45 .
S. Lehmann, C. Delaby, J. Touchon, C. Hirtz & A. Gabelle. (2013) Biomarkers of Alzheimer's disease: The present and the future. Revue Neurologique 169:10, pages 719-723.
Crossref
Thomas Arendt & Torsten Bullmann. (2013) Neuronal plasticity in hibernation and the proposed role of the microtubule-associated protein tau as a “master switch” regulating synaptic gain in neuronal networks. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 305:5, pages R478-R489.
Crossref
Annalisa Cavallini, Suzanne Brewerton, Amanda Bell, Samantha Sargent, Sarah Glover, Clare Hardy, Roger Moore, John Calley, Devaki Ramachandran, Michael Poidinger, Eric Karran, Peter Davies, Michael Hutton, Philip Szekeres & Suchira Bose. (2013) An Unbiased Approach to Identifying Tau Kinases That Phosphorylate Tau at Sites Associated with Alzheimer Disease. Journal of Biological Chemistry 288:32, pages 23331-23347.
Crossref
Harald Lund, Richard F. Cowburn, Elin Gustafsson, Kia Strömberg, Anne Svensson, Leif Dahllund, David Malinowsky & Dan Sunnemark. (2013) Tau-Tubulin Kinase 1 Expression, Phosphorylation and Co-Localization with Phospho-Ser422 Tau in the Alzheimer's Disease Brain. Brain Pathology 23:4, pages 378-389.
Crossref
Pradip K. Kamat, Shivika Rai & Chandishwar Nath. (2013) Okadaic acid induced neurotoxicity: An emerging tool to study Alzheimer's disease pathology. NeuroToxicology 37, pages 163-172.
Crossref
Jhoana Mendoza, Michiko Sekiya, Taizo Taniguchi, Koichi M. Iijima, Rong Wang & Kanae Ando. (2013) Global Analysis of Phosphorylation of Tau by the Checkpoint Kinases Chk1 and Chk2 in vitro . Journal of Proteome Research 12:6, pages 2654-2665.
Crossref
Nguyen-Vi Mohamed, Thibaut Herrou, Vanessa Plouffe, Nicolas Piperno & Nicole Leclerc. (2013) Spreading of tau pathology in Alzheimer's disease by cell-to-cell transmission. European Journal of Neuroscience 37:12, pages 1939-1948.
Crossref
Masha G. Savelieff, Sanghyun Lee, Yuzhong Liu & Mi Hee Lim. (2013) Untangling Amyloid-β, Tau, and Metals in Alzheimer’s Disease. ACS Chemical Biology 8:5, pages 856-865.
Crossref
Antoine Leboucher, Cyril Laurent, Francisco-José Fernandez-Gomez, Sylvie Burnouf, Laetitia Troquier, Sabiha Eddarkaoui, Dominique Demeyer, Raphaëlle Caillierez, Nadège Zommer, Emmanuelle Vallez, Kadiombo Bantubungi, Christophe Breton, Pascal Pigny, Valérie Buée-Scherrer, Bart Staels, Malika Hamdane, Anne Tailleux, Luc Buée & David Blum. (2013) Detrimental Effects of Diet-Induced Obesity on τ Pathology Are Independent of Insulin Resistance in τ Transgenic Mice. Diabetes 62:5, pages 1681-1688.
Crossref
Eric Duplan, Jean Sevalle, Julien Viotti, Thomas Goiran, Charlotte Bauer, Paul Renbaum, Ephrat Levy-Lahad, Clément A. Gautier, Olga Corti, Nathalie Leroudier, Frédéric Checler & Cristine Alves da Costa. (2013) Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription. Journal of Molecular Cell Biology 5:2, pages 132-142.
Crossref
Sylvie Burnouf, Alberto Martire, Maxime Derisbourg, Cyril Laurent, Karim Belarbi, Antoine Leboucher, Francisco J. Fernandez‐Gomez, Laetitia Troquier, Sabiha Eddarkaoui, Marie‐Eve Grosjean, Dominique Demeyer, Anne Muhr‐Tailleux, Alain Buisson, Nicolas Sergeant, Malika Hamdane, Sandrine Humez, Patrizia Popoli, Luc Buée & David Blum. (2012) NMDA receptor dysfunction contributes to impaired brain‐derived neurotrophic factor‐induced facilitation of hippocampal synaptic transmission in a T au transgenic model . Aging Cell 12:1, pages 11-23.
Crossref
Ludovic Martin, Xenia Latypova, Cornelia M. Wilson, Amandine Magnaudeix, Marie-Laure Perrin, Catherine Yardin & Faraj Terro. (2013) Tau protein kinases: Involvement in Alzheimer's disease. Ageing Research Reviews 12:1, pages 289-309.
Crossref
Basil H. Ridha & Tarek A. Yousry. 2013. Imaging of the Brain. Imaging of the Brain 947 947.e19 .
Mitsuko Hashiguchi & Toshio Hashiguchi. 2013. 121 160 .
David Blum, Ursula Sandau, Cyril Laurent, Vânia Batalha, Antoine Leboucher, Malika Hamdane, Florence Pasquier, Detlev Boison, Luc Buée & Luísa V. Lopes. 2013. Adenosine. Adenosine 385 407 .
Thomas A. Bayer, Sadim Jawhar, Jessica L. Wittnam & Oliver Wirths. 2013. Neuroscience in the 21st Century. Neuroscience in the 21st Century 2953 2969 .
Carlos Carrasco-Gallardo, Gonzalo A. Farías, Patricio Fuentes, Fernando Crespo & Ricardo B. Maccioni. (2012) Can Nutraceuticals Prevent Alzheimer's Disease? Potential Therapeutic Role of a Formulation Containing Shilajit and Complex B Vitamins. Archives of Medical Research 43:8, pages 699-704.
Crossref
Yan WEI, Jun-Ye MIAO & Ying LIU. (2012) Endogenous and Exogenous Factors in Hyperphosphorylation of Tau in Alzheimer′s Disease*. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 39:8, pages 778-784.
Crossref
Katryna Cisek, Jordan R. Jensen, Nicolette S. Honson, Kelsey N. Schafer, Grace L. Cooper & Jeff Kuret. (2012) Ligand electronic properties modulate tau filament binding site density. Biophysical Chemistry 170, pages 25-33.
Crossref
Victor L VillemagneShozo Furumoto, Michelle Fodero-Tavoletti, Ryuichi Harada, Rachel S Mulligan, Yukitsuka Kudo, Colin L Masters, Kazuhiko Yanai, Chistopher C Rowe & Nobuyuki Okamura. (2012) The challenges of tau imaging. Future Neurology 7:4, pages 409-421.
Crossref
Qi Zhong, Erin E. Congdon, Haikady N. Nagaraja & Jeff Kuret. (2012) Tau Isoform Composition Influences Rate and Extent of Filament Formation. Journal of Biological Chemistry 287:24, pages 20711-20719.
Crossref
Charlotte Delay, Wim Mandemakers & Sébastien S. Hébert. (2012) MicroRNAs in Alzheimer's disease. Neurobiology of Disease 46:2, pages 285-290.
Crossref
Kelsey N. Schafer, Sohee Kim, Anastasios Matzavinos & Jeff Kuret. (2012) Selectivity requirements for diagnostic imaging of neurofibrillary lesions in Alzheimer's disease: A simulation study. NeuroImage 60:3, pages 1724-1733.
Crossref
Michala Kolarova, Francisco García-Sierra, Ales Bartos, Jan Ricny & Daniela Ripova. (2012) Structure and Pathology of Tau Protein in Alzheimer Disease. International Journal of Alzheimer's Disease 2012, pages 1-13.
Crossref
Sébastien S. Hébert, Nicolas Sergeant & Luc Buée. (2012) MicroRNAs and the Regulation of Tau Metabolism. International Journal of Alzheimer's Disease 2012, pages 1-6.
Crossref
David A. Zacharias, Matthew Mullen & Sonia Lobo Planey. (2012) Antiproliferative Factor-Induced Changes in Phosphorylation and Palmitoylation of Cytoskeleton-Associated Protein-4 Regulate Its Nuclear Translocation and DNA Binding. International Journal of Cell Biology 2012, pages 1-13.
Crossref
Yasmina Talmat-Amar, Yoan Arribat, Christelle Redt-Clouet, Sébastien Feuillette, Anne-Laure Bougé, Magalie Lecourtois & Marie-Laure Parmentier. (2011) Important neuronal toxicity of microtubule-bound Tau in vivo in Drosophila. Human Molecular Genetics 20:19, pages 3738-3745.
Crossref
Dennis W. Dickson, Jean‐Jaques Hauw, Yves Agid & Irene Litvan. 2011. Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders. Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders 135 155 .
Jordan R. Jensen, Katryna Cisek, Nicolette S. Honson & Jeff Kuret. (2011) Ligand polarizability contributes to tau fibril binding affinity. Bioorganic & Medicinal Chemistry 19:17, pages 5147-5154.
Crossref
Ludovic Martin, Guylene Page & Faraj Terro. (2011) Tau phosphorylation and neuronal apoptosis induced by the blockade of PP2A preferentially involve GSK3β. Neurochemistry International 59:2, pages 235-250.
Crossref
Karim Belarbi, Sylvie Burnouf, Francisco-Jose Fernandez-Gomez, Cyril Laurent, Sophie Lestavel, Martin Figeac, Audrey Sultan, Laetitia Troquier, Antoine Leboucher, Raphaëlle Caillierez, Marie-Eve Grosjean, Dominique Demeyer, Hélène Obriot, Ingrid Brion, Bérangère Barbot, Marie-Christine Galas, Bart Staels, Sandrine Humez, Nicolas Sergeant, Susanna Schraen-Maschke, Anne Muhr-Tailleux, Malika Hamdane, Luc Buée & David Blum. (2011) Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology. Neurobiology of Disease 43:2, pages 486-494.
Crossref
Katerina Papanikolopoulou & Efthimios M. C. Skoulakis. (2011) The Power and Richness of Modelling Tauopathies in Drosophila. Molecular Neurobiology 44:1, pages 122-133.
Crossref
C.M. Dhaenens, H. Tran, M.-L. Frandemiche, C. Carpentier, S. Schraen-Maschke, A. Sistiaga, M. Goicoechea, S. Eddarkaoui, E. Van Brussels, H. Obriot, A. Labudeck, M.H. Gevaert, F. Fernandez-Gomez, N. Charlet-Berguerand, V. Deramecourt, C.A. Maurage, L. Buée, A. Lopez de Munain, B. Sablonnière, M.L. Caillet-Boudin & N. Sergeant. (2011) Mis-splicing of Tau exon 10 in myotonic dystrophy type 1 is reproduced by overexpression of CELF2 but not by MBNL1 silencing. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1812:7, pages 732-742.
Crossref
Kelsey N. Schafer, Dhiraj P. Murale, Kibong Kim, Katryna Cisek, Jeff Kuret & David G. Churchill. (2011) Structure–activity relationship of cyclic thiacarbocyanine tau aggregation inhibitors. Bioorganic & Medicinal Chemistry Letters 21:11, pages 3273-3276.
Crossref
Alexander Kurz & Robert Perneczky. (2011) Novel insights for the treatment of Alzheimer's disease. Progress in Neuro-Psychopharmacology and Biological Psychiatry 35:2, pages 373-379.
Crossref
Ann Van der Jeugd, Tariq Ahmed, Sylvie Burnouf, Karim Belarbi, Malika Hamdame, Marie-Eve Grosjean, Sandrine Humez, Detlef Balschun, David Blum, Luc Buée & Rudi D’Hooge. (2011) Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission. Neurobiology of Learning and Memory 95:3, pages 296-304.
Crossref
Nicolas Sergeant & Luc Buée. 2011. Animal Models of Dementia. Animal Models of Dementia 449 468 .
Nicolas Sergeant & Luc Buée. 2011. Cytoskeleton of the Nervous System. Cytoskeleton of the Nervous System 83 132 .
Thomas Vanhelmont, Tom Vandebroek, Ann De Vos, Dick Terwel, Katleen Lemaire, Jayamani Anandhakumar, Vanessa Franssens, Erwin Swinnen, Fred Van Leuven & Joris Winderickx. (2010) Serine-409 phosphorylation and oxidative damage define aggregation of human protein tau in yeast. FEMS Yeast Research 10:8, pages 992-1005.
Crossref
Thomas Wisniewski & Einar M. Sigurdsson. (2010) Murine models of Alzheimer's disease and their use in developing immunotherapies. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1802:10, pages 847-859.
Crossref
Luc Buée, David Blum, Stéphanie Bombois, Valérie Buée-Scherrer, Marie-Laure Caillet-Boudin, Morvane Colin, Vincent Deramecourt, Claire-Marie Dhaenens, Marie-Christine Galas, Malika Hamdane, Sandrine Humez, Claude-Alain Maurage, Florence Pasquier, Bernard Sablonnière, Susanna Schraen-Maschke & Nicolas Sergeant. (2010) Comment les acteurs moléculaires de la pathologie Alzheimer permettent de comprendre la démence ? Quelles conséquences diagnostiques et thérapeutiques ?. Therapies 65:5, pages 401-407.
Crossref
Yumiko Motoi, Naruhiko Sahara, Taiki Kambe & Nobutaka Hattori. (2010) Tau and neurodegenerative disorders. BioMolecular Concepts 1:2, pages 131-145.
Crossref
Katerina Papanikolopoulou, Stylianos Kosmidis, Sofia Grammenoudi & Efthimios M.C. Skoulakis. (2010) Phosphorylation differentiates tau-dependent neuronal toxicity and dysfunction. Biochemical Society Transactions 38:4, pages 981-987.
Crossref

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