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Fecal volatile organic compounds: a novel, cheaper method of diagnosing inflammatory bowel disease?

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Iftikhar Ahmed, Faisal Fayyaz, Moneeb Nasir, Zafar Niaz, Manuele Furnari & Lorna Perry. (2016) Extending landscape of volatile metabolites as novel diagnostic biomarkers of inflammatory bowel disease – a review. Scandinavian Journal of Gastroenterology 51:4, pages 385-392.
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Mai Kato, Momoka Yamaguchi, Akira Ooka, Ryota Takahashi, Takuji Suzuki, Keita Onoda, Yuko Yoshikawa, Yuta Tsunematsu, Michio Sato, Yasukiyo Yoshioka, Miki Igarashi, Sumio Hayakawa, Kumiko Shoji, Yutaka Shoji, Tomohisa Ishikawa, Kenji Watanabe & Noriyuki Miyoshi. (2023) Non-target GC–MS analyses of fecal VOCs in NASH-hepatocellular carcinoma model STAM mice. Scientific Reports 13:1.
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Elora Fournier, Jeremy Ratel, Sylvain Denis, Mathilde Leveque, Philippe Ruiz, Carine Mazal, Frederic Amiard, Mathieu Edely, Valerie Bezirard, Eric Gaultier, Bruno Lamas, Eric Houdeau, Erwan Engel, Fabienne Lagarde, Lucie Etienne-Mesmin, Muriel Mercier-Bonin & Stéphanie Blanquet-Diot. (2023) Exposure to polyethylene microplastics alters immature gut microbiome in an infant in vitro gut model. Journal of Hazardous Materials 443, pages 130383.
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Sofie Bosch, Dion S.J. Wintjens, Alfian Wicaksono, Johan Kuijvenhoven, René van der Hulst, Pieter Stokkers, Emma Daulton, Marieke J. Pierik, James A. Covington, Tim G.J. de Meij & Nanne K.H. de Boer. (2020) The faecal scent of inflammatory bowel disease: Detection and monitoring based on volatile organic compound analysis. Digestive and Liver Disease 52:7, pages 745-752.
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Misaki Uchikawa, Mai Kato, Akika Nagata, Shunsuke Sanada, Yuto Yoshikawa, Yuta Tsunematsu, Michio Sato, Takuji Suzuki, Tsutomu Hashidume, Kenji Watanabe, Yuko Yoshikawa & Noriyuki Miyoshi. (2020) Elevated levels of proinflammatory volatile metabolites in feces of high fat diet fed KK-Ay mice. Scientific Reports 10:1.
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E. Mozdiak, A. N. Wicaksono, J. A. Covington & R. P. Arasaradnam. (2019) Colorectal cancer and adenoma screening using urinary volatile organic compound (VOC) detection: early results from a single-centre bowel screening population (UK BCSP). Techniques in Coloproctology 23:4, pages 343-351.
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Naama Karu, Lu Deng, Mordechai Slae, An Chi Guo, Tanvir Sajed, Hien Huynh, Eytan Wine & David S. Wishart. (2018) A review on human fecal metabolomics: Methods, applications and the human fecal metabolome database. Analytica Chimica Acta 1030, pages 1-24.
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Oliver Gould, Ben de Lacy Costello, Amy Smart, Peter Jones, Angus Macmaster, Karen Ransley & Norman Ratcliffe. (2018) Gas Chromatography Mass Spectrometry (GC-MS) Quantification of Metabolites in Stool Using 13C Labelled Compounds. Metabolites 8:4, pages 75.
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Agnieszka Smolinska, Danyta I. Tedjo, Lionel Blanchet, Alexander Bodelier, Marieke J. Pierik, Ad A.M. Masclee, Jan Dallinga, Paul H.M. Savelkoul, Daisy M.A.E. Jonkers, John Penders & Frederik-Jan van Schooten. (2018) Volatile metabolites in breath strongly correlate with gut microbiome in CD patients. Analytica Chimica Acta 1025, pages 1-11.
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Sofie Bosch, Sofia el Manouni el Hassani, James A. Covington, Alfian N. Wicaksono, Marije K. Bomers, Marc A. Benninga, Chris J. J. Mulder, Nanne K. H. de Boer & Tim G. J. de Meij. (2018) Optimized Sampling Conditions for Fecal Volatile Organic Compound Analysis by Means of Field Asymmetric Ion Mobility Spectrometry. Analytical Chemistry 90:13, pages 7972-7981.
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Shaocun Zhang, Xiaocang Cao & He Huang. (2017) Sampling Strategies for Three-Dimensional Spatial Community Structures in IBD Microbiota Research. Frontiers in Cellular and Infection Microbiology 7.
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Anthony Corfield. (2016) Eukaryotic protein glycosylation: a primer for histochemists and cell biologists. Histochemistry and Cell Biology 147:2, pages 119-147.
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Florian Rieder, Satya Kurada, David Grove, Frank Cikach, Rocio Lopez, Nishaben Patel, Amandeep Singh, Naim Alkhouri, Bo Shen, Aaron Brzezinski, Mark Baker, Claudio Fiocchi & Raed A Dweik. (2016) A Distinct Colon-Derived Breath Metabolome is Associated with Inflammatory Bowel Disease, but not its Complications. Clinical and Translational Gastroenterology 7:11, pages e201.
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D.T. Reid, B. McDonald, T. Khalid, T. Vo, L.P. Schenck, M.G. Surette, P.L. Beck, R.A. Reimer, C.S. Probert, K.P. Rioux & B. Eksteen. (2016) Unique microbial-derived volatile organic compounds in portal venous circulation in murine non-alcoholic fatty liver disease. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1862:7, pages 1337-1344.
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Claire Turner. (2016) Techniques and issues in breath and clinical sample headspace analysis for disease diagnosis. Bioanalysis 8:7, pages 677-690.
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Lucy C. Hicks, Juzheng Huang, Sacheen Kumar, Sam T. Powles, Timothy R. Orchard, George B. Hanna & Horace R.T. Williams. (2015) Analysis of Exhaled Breath Volatile Organic Compounds in Inflammatory Bowel Disease: A Pilot Study. Journal of Crohn's and Colitis 9:9, pages 731-737.
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